Made available in DSpace on 2015-04-14T13:32:58Z (GMT). No. of bitstreams: 1 439172.pdf: 4325979 bytes, checksum: fb686c7a6cc068a1adc08b2feaab0ecb (MD5) Previous issue date: 2011-03-15 / Background: Alterations to lung development in preterm infants is characterized by decreased alveolarization and dysmorphic vasculature. Has been considered the possibility that changes associated with perinatal factors decrease lung volume and quality of ventilation distribution. Objective: To measure the functional residual capacity and heterogeneity of ventilation in preterm infants and to study their association with perinatal factors. Methods: This is a cross-sectional study involving preterm infants corrected age of 8 to 13 months. Were measured at functional residual capacity (FRC) and ventilation inhomogeneity using the lung clearance index (LCI) by the technique multiple breath inert gas washout (MBW) with sulfur hexafluoride (SF6) to 4%, with sedation, using a ultrasonic flowmeter. The statistical analysis used the Student t test and linear regression. Results: We studied 28 preterm infants with gestational age (GA) (mean ?SD) of 31? 2.9 weeks, with of 7.88 ?0.6 and equal to 19.7 ?4.3 ml.kg-1. Positive correlation were found between LCI and males and intrauterine growth restriction (p <0.05). Premature rupture of membranes were negative correlation with LCI (p <0.05). Conclusion: The results suggest that this sample, male sex, the IUGR and premature rupture of membranes affect LCI in preterm infants. The FRC was not associated with prematurity or other pre-natal and post-natal factors. / Introdu??o: A altera??o no desenvolvimento pulmonar em prematuros ? caracterizada por redu??o na alveolariza??o e vasculariza??o dism?rfica. Tem sido considerada a possibilidade de que altera??es associadas a fatores perinatais diminuam volumes pulmonares e a qualidade da distribui??o da ventila??o. Objetivo: Medir a heterogeneidade da ventila??o e a capacidade residual funcional em prematuros e estudar suas associa??es com fatores perinatais. M?todos: Este ? um estudo transversal envolvendo prematuros com idade corrigida de 8 a 13 meses. Foram medidas a capacidade residual funcional (CRF) e a ventila??o heterog?nea utilizando o lung clearence ?ndex (LCI) atrav?s da t?cnica multiple breath inert gas washout (MBW) com hexafluoreto de enxofre (SF6) a 4%, com seda??o, usando um medidor de fluxo ultrass?nico. Na an?lise estat?stica foi usado o teste t de Student e a regress?o linear. Resultados: Foram estudados 28 prematuros com idade gestacional (IG) (m?dia?dp) de 31?2,9 semanas, com LCI de 7,88?0,6 e CRF igual a 19,7?4,3 ml.kg-1. Houve correla??o positiva entre LCI e sexo masculino e restri??o do crescimento intrauterino (RCIU) (p<0,05). Houve correla??o negativa entre LCI e ruptura prematura das membranas (ruprema) (p<0,05). Conclus?o: Os resultados encontrados sugerem, que nesta amostra, o sexo masculino, o RCIU e a ruprema influenciaram o LCI em prematuros. A CRF n?o foi associada ? prematuridade ou outros fatores perinatais.

Made available in DSpace on 2015-04-14T13:33:02Z (GMT). No. of bitstreams: 1 446507.pdf: 436565 bytes, checksum: 4c823a43f4c8a59fe78a718fa8291c1a (MD5) Previous issue date: 2013-03-04 / Aims: The aims of the study were to assess the necessity of lateral chest X-rays in newborns on mechanical ventilation in a neonatal intensive care unit, and to estimate the dose of radiation exposure during such exams. Methods: Cross-sectional study performed at the neonatal intensive care unit of a city hospital in Porto Alegre (Brazil). Patients were followed on daily basis, and all chest x-rays were registered while they were on mechanical ventilation, including the first day postextubation. Two experienced neonatologists were included as external observers, to assess, independently, the necessity of having performed each of the lateral views of chest x-rays all newborns had. Results: Sixty five newborns were included. There were 426 chest x-rays requisitions during the study period. Of these, 374 were antero-posterior plus lateral views and 52 were only antero-posterior views. The index of chest x-rays requisitions was of 0,8 x-rays per newborn per day, corresponding to 0,7 antero-posterior and lateral views per newborn per day and 0,1 antero-posterior x-rays per newborn per day. The use of the antero-posterior view associated with the lateral view compared to only the antero-posterior view increases three-fold the exposition of the newborn to ionizing radiation. Conclusion: We noticed the lack of well-defined guidelines on the use of the lateral view of chest x-rays in neonatal intensive care units. Many institutions, including ours, are performing chest-x-rays lateral views at a rate greater than needed. This behavior leads to an elevated exposition of radiation dose to the newborns, potentially leading to future consequences. / Objetivos: Os objetivos do presente estudo s?o avaliar a necessidade das radiografias de t?rax em perfil dos rec?m-nascidos submetidos ? ventila??o mec?nica de uma Unidade de Tratamento Intensivo Neonatal, bem como determinar a dose de exposi??o ? radia??o durante esses exames.M?todos: Estudo prospectivo, transversal, conduzido na Unidade de Tratamento Intensivo Neonatal de um hospital em Porto Alegre (Brasil). O estudo foi realizado entre 01 de dezembro de 2011 e 01 de junho de 2012. O paciente foi acompanhado diariamente, anotando-se todas as radiografias de t?rax realizadas durante o tempo em que permaneceu em ventila??o mec?nica at? o 1? dia p?s-extuba??o (inclusive). Participaram, como avaliadores externos, dois neonatologistas com longa experi?ncia na ?rea. Ambos avaliaram, de forma independente, a necessidade ou n?o de se realizar a radiografia de t?rax na posi??o em perfil para cada exame solicitado. Resultados: Sessenta e cinco crian?as foram inclu?das. Houve 426 requisi??es de radiografias de t?rax durante o per?odo do estudo. Dessas, 374 foram proje??es ?ntero-posteriores e perfil, enquanto que, em 52, foi realizado somente o ?ntero-posterior. O ?ndice de solicita??es de radiografias de t?rax equivaleu a 0,8 radiografias por crian?a por dia de interna??o, correspondendo a 0,7 radiografias ?ntero-posterior e perfil por crian?a por dia e 0,1 radiografia ?ntero-posterior por crian?a por dia. O fato de se realizar um exame de t?rax em ?ntero-posterior e perfil, comparado quando realizado apenas o ?ntero-posterior, aumenta em mais de 3 vezes a exposi??o do rec?m- nascido ? radia??o ionizante. Conclus?o: Observamos que n?o existem diretrizes bem definidas e claras sobre a realiza??o da radiografia de t?rax em perfil nas Unidades de Tratamento Intensivo Neonatais. Muitas institui??es, assim como a nossa, est?o realizando proje??es em perfil em uma frequ?ncia muito maior do que a necess?ria. Esse comportamento resulta em uma exposi??o de dose elevada para esses rec?m-nascidos, podendo gerar consequ?ncias futuras.

Made available in DSpace on 2015-04-14T13:37:47Z (GMT). No. of bitstreams: 1 411289.pdf: 593663 bytes, checksum: 88c6457e519fda0394637ef4894afaf9 (MD5) Previous issue date: 2009-01-13 / A partir da defini??o de mal e da caracteriza??o da personagem esta disserta??o prop?e uma analise do mal como conceito moral que forma o car?ter da personagem. Para isso obedecemos a seguinte ordem: conceituar e mal atrav?s de premissas filos?ficas; apresentar como o mal aparece na obra A laranja mec?nica de Anthony Burgess e apontar como o mal ? representado atrav?s da personagem protagonista.

O tema desta pesquisa refere-se ao tratamento numérico de estruturas de pavimentos, dando ênfase à utilização do método dos elementos de contorno - MEC para o tratamento de elementos planos, enquanto os elementos lineares serão tratados através do método dos elementos finitos - MEF. Busca-se contribuir com uma série de trabalhos realizados nesta área, principalmente com a consideração do efeito da excentricidade do eixo neutro das barras em relação à superfície neutra da placa somando-o, portanto, ao fenômeno de flexão desta última. A técnica de acoplamento dos elementos estruturais utilizada foi a técnica das sub-regiões, que facilita a visualização do problema da combinação e viabiliza o uso da técnica de condensação estática na resolução do sistema de equações. / This research refers to the numeric analysis of structures, emphasizing the use of the boundary element method - BEM - in the discretization of the plates, while the linear elements wil be formulated through the finite element method - FEM. The aim is to contribute with a number of works related to this subject, specially in the consideration of the effect of the stiffeners eccentricity in relation to the plates neutral surface, in addition to its bending state. The tool adopted to fulfill the coupling among these kinds of structural elements is the well-known sub region or multi-domain technique, which works well with the static condensation technique for solving the sparse system of equation generated.

Submitted by Sandra Pereira (srpereira@ufrrj.br) on 2016-10-13T12:25:00Z No. of bitstreams: 1 2016 - Sheyla Moreira Gon?alves.pdf: 3716146 bytes, checksum: eaee6e62414cd3d497528f597f1abab5 (MD5) / Made available in DSpace on 2016-10-13T12:25:00Z (GMT). No. of bitstreams: 1 2016 - Sheyla Moreira Gon?alves.pdf: 3716146 bytes, checksum: eaee6e62414cd3d497528f597f1abab5 (MD5) Previous issue date: 2016-02-23 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / The use of active packaging incorporated with natural antimicrobials as essential oils (EOs) for food preservation is a modern concept for the food industry. The objective of this study was to characterize cellulose acetate film (CA) incorporated with EOs and their combinations and/or added plasticizer, evaluating the influence of additives on the behavior of these materials. It is characterized as the thickness of the films, visual aspect, chemical structure, surface, mechanical strength, water vapor rate of transmission (WVRT) and antimicrobial activity. Through technique "casting" were obtained films incorporated with 50% (w/v) of EOs oregano or cinnamon or sweet fennel or combinations thereof and/or glycerol (5, 10, 20 and 30% (w/v)). Having as controls only films containing 50% (w/v) glycerol, and CA pure film, a total 41 treatments. The incorporation of EOs did not change the thickness and transparency of the films, but it reduced the WVRT. The color parameters L *, a* and b* were affected by the incorporation with EOs and/or glycerol the films exhibited clear with different colors compared with the AC pure film. Incorporating the most EOs cause increased tensile strength (TS) of the modulus of elasticity (ME) and reduced elongation at break (EB), except for the film with fennel EO (FEO) who presented plasticizer power differing from the other for all the evaluated mechanical parameters. The drilling force (DF) has increased to most films EOs incorporated with the exception of the film incorporated with the three EOs. The scanning electron microscopy (SEM) images revealed that most of the EOs and their combinations did not cause changes in the surface and cross-sectional area of the films, except the film with FEO. In the spectra of infrared spectroscopy with Fourier transform (FTIR), it observed that the interactions between the polymer matrix and most EOs were similar except for the film with FEO. As for the antibacterial efficiency in vitro, only the film incorporated with FEO showed no efficacy against Staphylococcus aureus (Gram +) and Escherichia coli (Gram +). It was observed that glycerol causes increased thickness and WVRT the AC films, however, the active films with EOs does not modify the parameter to most treatments. Transparency was not affected for most films. The addition of glycerol for most films incorporated with EOs caused reduction of TS, the ME and increased EB and DF. From the SEM pictures it can be observed that the glycerol promoted the emergence of porous structures, networked or compact, depending on the EO concentration and glycerol. The FTIR spectral showed that glycerol has different interactions, depending on the embedded EOs. The antibacterial efficiency of films with EO oregano or cinnamon or oregano more cinnamon has been improved with the presence of glycerol, while the others were not affected. In the face of changes in functional properties observed, it appears that with the additivation materials it is necessary to characterize them to define their applicability / O emprego de embalagens ativas incorporadas com antimicrobianos naturais, como os ?leos essenciais (OEs) para conserva??o de alimentos, representa um conceito moderno para a ind?stria aliment?cia. Objetivou-se neste trabalho caracterizar filmes de acetato de celulose (AC) incorporados com OEs e suas combina??es e/ou adi??o de plastificante, avaliando as influ?ncias da aditiva??o no comportamento f?sico e mec?nico destes materiais. Caracterizou-se os filmes quanto ? espessura, aspectos visuais, estrutura qu?mica, superf?cie, resist?ncia mec?nica, taxa de transmiss?o ao vapor de ?gua (TTVA) e atividade antimicrobiana. Atrav?s da t?cnica ?casting? foram obtidos filmes incorporados com 50% (p/v) de OEs de or?gano, canela, funcho doce ou suas combina??es e/ou glicerol (5, 10, 20 e 30% (p/v)). Tendo como controles filmes contendo somente 50% (p/v) de glicerol, e filme de AC puro, totalizando 41 tratamentos. A incorpora??o de OEs n?o modificou a espessura e transpar?ncia dos filmes, por?m causou redu??o da TTVA. Os par?metros de cor L*, a* e b* foram afetados pela incorpora??o de OEs e/ou glicerol tendo os filmes apresentado-se claros com diferentes cores em compara??o com o filme de AC puro. A incorpora??o da maioria dos OEs causou aumento da resist?ncia ? tra??o (RT), do m?dulo de elasticidade (ME) e redu??o do alongamento na ruptura (AR), com exce??o para o filme com OE de funcho (OEF) que apresentou poder plastificante diferindo dos demais para todos os par?metros mec?nicos avaliados. A for?a de perfura??o (FP) aumentou para a maioria dos filmes incorporados com OEs, a exce??o do filme incorporado com os tr?s OEs. As imagens de microscopia eletr?nica de varredura (MEV) revelaram que a maioria dos OEs e suas combina??es n?o causaram mudan?as na superf?cie e regi?o transversal dos filmes, a exce??o do filme com OEF. Nos espectros da espectroscopia no infravermelho com transformada de Fourier (FTIR), notou-se que as intera??es entre a matriz polim?rica e a maioria dos OEs foram semelhantes, com exce??o para o filme com OEF. Quanto ? efici?ncia antibacteriana in vitro, somente o filme incorporado com OEF n?o apresentou efetividade contra Staphylococcus aureus (Gram +) e Escherichia coli (Gram -). Foi observado que o glicerol causou aumento da espessura e TTVA nos filmes de AC, por?m, nos filmes ativos com OEs n?o modificou o par?metro para maioria dos tratamentos. A transpar?ncia n?o foi afetada para a maioria dos filmes. A adi??o de glicerol para a maioria dos filmes incorporados com OEs causou redu??o da RT, do ME e aumento do AR e FP. Pelas imagens do MEV observa-se que o glicerol promoveu o surgimento de estruturas porosas, em rede ou compactas, dependendo do OE e concentra??o de glicerol. Os espectros da FTIR demonstraram que o glicerol apresentou diferentes intera??es, dependendo do OE incorporado. A efici?ncia antibacteriana dos filmes com OE de or?gano ou canela ou or?gano mais canela foi melhorada com a presen?a de glicerol, enquanto os demais n?o sofreram influ?ncia. Diante das varia??es nas propriedades funcionais observadas, verifica-se que com a aditiva??o dos materiais ? necess?rio caracteriza??o para definir sua aplicabilidade

Submitted by PPG Medicina e Ci?ncias da Sa?de (medicina-pg@pucrs.br) on 2018-12-05T13:29:31Z No. of bitstreams: 1 RUY_DE_ALMEIDA_BARCELLOS.pdf: 2171813 bytes, checksum: d242fe874538146ea8081420b788cadb (MD5) / Approved for entry into archive by Sheila Dias (sheila.dias@pucrs.br) on 2018-12-06T18:13:57Z (GMT) No. of bitstreams: 1 RUY_DE_ALMEIDA_BARCELLOS.pdf: 2171813 bytes, checksum: d242fe874538146ea8081420b788cadb (MD5) / Made available in DSpace on 2018-12-06T18:20:07Z (GMT). No. of bitstreams: 1 RUY_DE_ALMEIDA_BARCELLOS.pdf: 2171813 bytes, checksum: d242fe874538146ea8081420b788cadb (MD5) Previous issue date: 2018-09-24 / Objective: To evaluate the impact of the implantation of a checklist during multidisciplinary daily round in the period of using invasive mechanical ventilation (MV) and permanence in the ICU. Methods: In a non-randomized clinical trial with historical controls, 466 patients submitted to MV were evaluated in a Hospital in Caxias do Sul (RS). Of this total, 235 and 231 were evaluated in the pre-intervention and post-intervention phases, respectively. The outcomes studied were SAPS-3, SOFA, frequency of infections, ICU stay, days of MV, reintubations, rehospitalizations, deaths in the ICU and hospital. Results: There was a significant reduction after the routine use of the checklist in the lenght of permanence in 37.5% (p <0.001) and 60% (p <0.001) in the time of mechanical ventilation. The frequency of pulmonary focus infection was reduced by 11.9% (p = 0.030). Conclusions: The multidisciplinarity structured through the use of checklists has an impact on the reduction of the days of use of mechanical ventilation and stay in the ICU. / Objetivo: Avaliar o impacto da implanta??o de uma lista de verifica??o durante round di?rio multiprofissional nos tempos de ventila??o mec?nica invasiva (VM) e perman?ncia na UTI. M?todos: Em um ensaio cl?nico n?o randomizado com controles hist?ricos, foram avaliados 466 pacientes submetidos ? VM em um hospital em Caxias do Sul (RS). Foram avaliados 235 e 231 pacientes nas fases pr?-interven??o e p?s-interven??o respectivamente. As vari?veis estudadas foram: Simplified Acute Physiology Score (SAPS-3), Sequential Organ Failure Assessment (SOFA), frequ?ncia de infec??es, perman?ncia na UTI, dias de VM, reintuba??es, reinterna??es, ?bitos na UTI e hospitalar. Resultados: Houve redu??o significativa ap?s a implanta??o da lista de verifica??o no tempo de perman?ncia em 37,5% (p<0,001) e de 60% (p<0,001) no tempo de ventila??o mec?nica. A frequ?ncia de infec??o de foco pulmonar teve redu??o 11,9% (p=0,030). Conclus?es: A multidisciplinaridade estruturada atrav?s da utiliza??o da lista de verifica??o teve impacto na redu??o dos dias de utiliza??o de ventila??o mec?nica e perman?ncia na UTI.

Ce travail est consacré à l'étude des processus d'échange de charge et de perte d'énergie d'ions lourds très chargés ralentis, canalisés dans des cristaux minces de silicium. Les deux premiers chapitres présente le principe de la canalisation des ions lourds dans un cristal, l'ensemble des processus d'interaction ion-électrons et le principe de nos simulations d'échanges de charge et de trajectoires en conditions de canalisation.<br />Les chapitres suivants décrivent deux expériences réalisées à l'accélérateur de GSI de Darmstadt dont les principaux résultats sont les suivants : la probabilité par atome cible de capture mécanique (MEC) des ions U91+ de 20 MeV/u en fonction du paramètre d'impact (à l'aide de nos simulations), l'observation de la forte polarisation du gaz d'électrons cible par l'intermédiaire de la capture radiative (REC) et le ralentissement d'ions Pb81+ de 13 à 8,5 MeV/u en conditions de canalisation, pour lesquelles la capture électronique est fortement réduite.

Thèse numérisée par la Division de la gestion de documents et des archives de l'Université de Montréal

Methicillin-resistenta Staphylococcus aureus (MRSA) som bär på genen mecA, har förekommit och spridit sig över hela världen, främst i sjukhusmiljö, och orsakat utbrott av vårdrelaterade (så kallade nosokomiala) infektioner. Dessa infektioner kan inte behandlas med stafylokock-penicilliner och MRSA-bakterierna är ofta resistenta även mot flera andra grupper av antibiotika vilket medför att infektionerna ofta är påtagligt svårbehandlade. Under senare år har emellertid allt fler fall beskrivits av samhällsförvärvad MRSA infektion, det vill säga uppträdande av MRSA hos personer som tidigare ej har haft kontakt med sjukhusvård eller behandlats med antibiotika. Det har länge varit oklart om de samhällsförvärvade MRSA [community-acquired (CA-MRSA)] representerar spridning av bakterier från sjukhusmiljön ut till samhället eller om dessa MRSA är spontant uppträdande. Många av dessa stammar har dessutom visat sig bära på sjukdomsrelaterade gener som vanligen inte återfinns hos S. aureus, t.ex. Panton Valentine leukocidin (PVL) som associeras med hudinfektioner och allvarlig lunginflammation med hög dödlighet hos unga och annars friska individer. Denna avhandling beskriver den molekylära epidemiologin hos MRSA med fokus på samhällsförvärvade MRSA som utgjorde mer än hälften av samtliga fall av MRSA i Örebro län och som dessutom ofta producerade PVL toxinet, vars funktion vidare analyserades i detalj. Undersökning av ursprung och släktskap hos samtliga MRSA som isolerats i Örebro län, samt karaktärisering av det genetiskt element som kallas staphylococcal cassette chromosome mec (SCCmec) vilket innehåller genen mecA och ibland även andra resistensgener, visade att CA-MRSA inte är relaterade till de nosokomiala MRSA, och att dessa har uppstått oberoende av varandra. Flertalet MRSA visade sig dessutom bära på SCCmec, och resistensmekanismer, som tidigare inte beskrivits. Troligen har dessa MRSA uppstått genom ett genetiskt utbyte av SCCmec mellan methicillin-resistenta koagulas-negativa stafylokocker (MR-KNS), som utgör huvudparten av normalfloran på huden, och methicillin-känsliga S. aureus som därvid erhåller genen mecA och resistensmekanismer mot samtliga stafylokockantibiotika. I den här avhandlingen framläggs bevis för att ett sådant genetiskt utbyte har skett på Barnkliniken på Universitetssjukhuset i Örebro i slutet på 1990-talet, vilket resulterade i uppkomsten av en ny klon av MRSA som därefter orsakade ett allvarligt utbrott. Kartläggning av DNA-sekvensen hos flertalet unika SCCmec från svenska MRSA gav dessutom en bättre förståelse för hur resistens uppkommer och sprider sig, samt mekanismerna bakom detta. Dessa nya kunskaper kan bidra till en förbättrad diagnostik av MRSA. Detta är framför allt av stor betydelse eftersom nya effektiva kloner av MRSA verkar kunna uppstå ute i samhället med potential att orsaka svårbehandlade infektioner men även att sprida sig bland den friska befolkningen. / Material and methods - During a period of 14 years, around 2000 patients with head injuries were admitted to the emergency ward at Lindesberg County Hospital and Örebro Medical Centre Hospital. Six hundred subjects suffered from skull fracture and/or brain contusion and diagnosis was established using a computed tomography scan (CT). The degree of initial brain injury was estimated using the Swedish Reaction Level Scale (RLS). Sixty-six subjects were investigated with pure tone audiometry in close proximity to the trauma, and this gave an opportunity to study the issue of progress. The investigation took place two to 14 years after trauma, and the results were compared to matched control groups. A battery of different audiological methods was used to investigate peripheral and central auditory function, and a specially designed acoustic environmental room was also utilized. Cognition was investigated using a computer-based test-battery, text information process system (TIPS). Self-assessed hearing, cognition and quality of life were explored using different questionnaires. Results - A high percentage of peripheral and central auditory impairments and also cognitive shortcomings were demonstrated. Progress of SNHL was a common finding, and fracture, high age at trauma and large initial hearing loss predicted progress. Antibody-mediated autoimmunity as a mechanism behind posttraumatic progress of SNHL or clear evidence for sympathetic cochleolabyrinthitis could not be demonstrated. Binaural auditory deficits could be demonstrated when tested in a realistic acoustic environment. Tinnitus, vertigo and memory shortcomings proved to be common sequelae, even in a long-term perspectiveCognitive shortcomings were found in several of these well-rehabilitated subjects.On a group level, there was a good correlation between self-assessments and audiometric results, even if some individuals had a tendency to over- or underestimate their abilities. Conclusion - Auditory and cognitive long-term sequelae of CHI are a common finding even in well-rehabilitated and socially well-functioning subjects, as are vertigo and tinnitus. Vertigo and tinnitus are also common sequelae after CHI, therefore a basic audiovestibular investigation after CHI is recommended, at least in selected cases.Early awareness of the risk for hearing and cognitive sequelae after CHI could lead to measurements taken to prevent tension-related symptoms.Early detection of HI offers an opportunity to try immunosuppressive treatment in cases with a large initial SNHL.

Made available in DSpace on 2014-12-17T15:47:52Z (GMT). No. of bitstreams: 1 CassioHF_DISSERT.pdf: 1503543 bytes, checksum: f8c5d434affbf0ef65dde0a97d3eb071 (MD5) Previous issue date: 2010-02-22 / Despite the emergence of other forms of artificial lift, sucker rod pumping systems remains hegemonic because of its flexibility of operation and lower investment cost compared to other lifting techniques developed. A successful rod pumping sizing necessarily passes through the supply of estimated flow and the controlled wear of pumping equipment used in the mounted configuration. However, the mediation of these elements is particularly challenging, especially for most designers dealing with this work, which still lack the experience needed to get good projects pumping in time. Even with the existence of various computer applications on the market in order to facilitate this task, they must face a grueling process of trial and error until you get the most appropriate combination of equipment for installation in the well. This thesis proposes the creation of an expert system in the design of sucker rod pumping systems. Its mission is to guide a petroleum engineer in the task of selecting a range of equipment appropriate to the context provided by the characteristics of the oil that will be raised to the surface. Features such as the level of gas separation, presence of corrosive elements, possibility of production of sand and waxing are taken into account in selecting the pumping unit, sucker-rod strings and subsurface pump and their operation mode. It is able to approximate the inferente process in the way of human reasoning, which leads to results closer to those obtained by a specialist. For this, their production rules were based on the theory of fuzzy sets, able to model vague concepts typically present in human reasoning. The calculations of operating parameters of the pumping system are made by the API RP 11L method. Based on information input, the system is able to return to the user a set of pumping configurations that meet a given design flow, but without subjecting the selected equipment to an effort beyond that which can bear / Apesar do surgimento de outras t?cnicas de eleva??o artificial de petr?leo, sistemas de bombeio mec?nico mant?m-se hegem?nicos devido ? sua flexibilidade de atua??o e custo menor de investimento se comparada com outras t?cnicas de eleva??o desenvolvidas. Um dimensionamento de bombeio mec?nico bem sucedido necessariamente passa pelo atendimento da vaz?o prevista e pelo desgaste controlado dos equipamentos de bombeio utilizados na configura??o montada. Entretanto, a concilia??o destes elementos mostrase particularmente desafiadora, sobretudo para a maioria dos projetistas que lidam com este trabalho, que n?o possuem ainda a experi?ncia necess?ria para chegar a bons projetos de bombeio em tempo h?bil. Mesmo com a exist?ncia de diversos aplicativos computacionais no mercado com o objetivo de facilitar esta tarefa, eles precisam enfrentar um exaustivo processo de tentativa e erro at? chegar a combina??o mais adequada de equipamentos para instala??o no po?o. A proposta do presente trabalho consiste em desenvolver um sistema especialista no dimensionamento de sistemas de bombeio mec?nico. Ele tem a miss?o de guiar um engenheiro de petr?leo na tarefa de selecionar um conjunto de equipamentos apropriados ao contexto provido pelas caracter?sticas do ?leo que ser? produzido. Caracter?sticas como o n?vel de separa??o do g?s, presen?a de elementos corrosivos, possibilidade de produ??o de areia e de parafina??o s?o levados em considera??o na escolha da bomba de fundo, coluna de hastes e unidade de bombeio, bem como as caracter?sticas de opera??o dos mesmos. Ele ? capaz de aproximar seu processo de infer?ncia da forma do racioc?nio humano, o que gera resultados mais pr?ximos daqueles obtidos por um especialista. Para tanto, suas regras de produ??o foram elaboradas com base na teoria dos conjuntos fuzzy, capazes de modelar conceitos imprecisos tipicamente presentes no racioc?nio humano. Os c?lculos dos par?metros operacionais do sistema de bombeio s?o feitos por meio do m?todo API RP 11L. Com base em informa??es de entrada, o sistema ? capaz de retornar ao usu?rio um conjunto de configura??es de bombeio mec?nico que atendam uma determinada vaz?o de projeto, por?m sem submeter os equipamentos selecionados a um esfor?o al?m daquele que possam suportar