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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
171

Metamorfoses de Venus na poesia de Ovídio / Metamorphosis of Venus in Ovid¿s poetry

Orosco, Gabriela Strafacci, 1984- 11 July 2011 (has links)
Orientador: Isabella Tardin Cardoso / Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Estudos da Linguagem / Made available in DSpace on 2018-08-19T11:37:47Z (GMT). No. of bitstreams: 1 Orosco_GabrielaStrafacci_M.pdf: 1499304 bytes, checksum: 8dcba777729471fd896b80f8ef7a63bc (MD5) Previous issue date: 2011 / Resumo: O interesse deste estudo é observar a presença da deusa romana Vênus, cujo principal atributo é o amor, em obras do poeta romano Públio Ovídio Nasão (43 a. C - 17 / 18 d. C.), mais especificamente nos poemas Os Remédios do amor (Remedia Amoris) e em passagens selecionadas das Metamorfoses (Metamorphoseon Libri). Ao cotejar esses excertos, verifica-se que a deusa, seja metonimicamente (por exemplo, como sinônimo do substantivo "amor"), seja como personagem de aventuras e desventuras amorosas, abrange muito da poesia ovidiana e configura-se de diversas maneiras: no poema didático Remedia Amoris, por exemplo, Vênus é relacionada, com frequência, a narrativas de infelicidade amorosa. Nessa obra, o eu poético, propondo a cura do amor, cita a deusa como referência a histórias amorosas malfadadas. Observar a participação da deusa do amor em Metamorfoses, em que ela não é apenas referida como metonímia de seu atributo, como também é personagem de narrativas míticas, permite perceber com mais clareza em que medida os respectivos episódios mitológicos são mencionados ou aludidos também em Os Remédios do amor. Os excertos de Metamorfoses respectivos aos mitos referidos em Remedia compõem o corpus traduzido, a saber, Met. IV 169-189, X 298-739 e XIV 441-608 (bem como a comparação com sua menção em Remedia Amoris) é ponto de partida para uma análise da figura de Vênus. O estudo visa, ainda, contribuir modestamente para a discussão sobre a concepção do sentimento amoroso em Ovídio, em particular a ideia de amor como doença / Abstract: This study has as a central interest observing the presence of the Roman goddess Venus, whose main attribute is love, in Publius Ovidius Naso?s work (43 B. C - 17 / 18 A. D.), more specifically in the poems Remedia Amoris (Remedies for Love) and in selected passages of Metamorphoseon Libri (Metamorphoses). Throught the comparison among the latin passages pertaincing to both ovidian works, it is noticed that the goddess presence - either metonymically (for instance, as a synonymous for the noun "love") or as a character of amorous adventures or misadventures - comprises much of the ovidian poetry. In the didactic poem Remedia Amoris, for example, Venus is frequently related to unhappy love narratives. In Remedia the lyric self, purposing the cure for love, mentions the goddess as a reference to unlucky love stories. Observing in the Metamorphoses how the goddess of love participates as a mythical character, helps to perceive the allusion to mythological episodes that also takes part in Remedia Amoris. The respective excerpts of Metamorphoses (namely Met. IV 169-189, X 298-739 e XIV 441-608) that are mentioned in Remedia Amoris compose the corpus of our study. The translation of the selected passages of Metamorphoses, as well as a comparison with their mention in Remedia amoris, is the starting point for the analysis. The study aims also to modestly contribute for the reflection on the conception of the love feeling constituted in Ovid, mainly the idea of love as a disease / Mestrado / Linguistica / Mestre em Linguística
172

L'art urbain des graffitis : expérimentation des frontières esthétiques / Urban art of graffitis : experimentation of aesthetic boundaries

Burgi, Gary 14 November 2016 (has links)
Un graffiti est exposé à la vue de tous dans la rue : lieu du passage, de l’échange, de l’intenseproximité. Un regard doit-il/peut-il se constituer, se conformer à un lieu d’approximation, dedistance, de rencontre, de conflit ?Or, exposer ce type d’oeuvre ailleurs, semble, a priori, une hérésie ; sa décontextualisation, unpléonasme. En quoi l’acte d’exposer contredit-il cette pratique urbaine, si, littéralement, un graffitiest directement accessible à nos sens, exposé ? Le mur est-il une frontière qui fait écran, entre lemonde du réel et de l’irréel ?Une représentation persiste inconsciemment : l’art urbain peut aussi faireconsensus. Comment autrui intervient-il dans ce type de représentation ?Avec des hypothèses élaborées à partir d’oeuvres urbaines, un corpus d’image constituera uneméthode de recherche pour engager un dialogue avec le corps du passant, suivant les modalités deproduction ou de création de cette vision de graffiti.Une expérimentation des frontières esthétiques, peut-elle rendre compte, a posteriori, dudevenir de l’anonymat d’une oeuvre d’art réalisée sur les surfaces anonymes et phénoménales de laville ?La comparaison du corps d’un être humain à celui d’une ville, est-elle fortuite ? Cetteréduction de l’homme au mur, dit métaphoriquement, est-elle constitutive de rapportshumains ? Réels, fictifs ? Relatifs ?Comment l’art peut-il former dans l’urgence un regard historique, voire collectif, sans ladistance ? / A graffiti is exposed for every body in the street : place of passage, exchange, of the intenseproximity. Should or could a glance be able to constitute itself or to observe itself, a place ofapproximation, of distance, of meeting, of conflict ?But, to expose this type of work elsewhere, seems, a priori, a heresy ; its decontextualization,a pleonasm. How does the act of exposing contradict this urban practice, if, literally, a graffiti isdirectly accessible to our senses, exposed ? Is the wall a boundary between the real and the unreal ?A representation persists unconsciously : urban art can also make a consensus. How doesanother person intervene in this type of representation ?With hypotheses developed from urban works, a corpus of images will constitute a researchmethod for engaging a dialogue with the body of the passer-by, according to the modalities ofproduction or creation of this vision of graffiti.Can an experiment on aesthetic borders explain, a posteriori, the future of the anonymity of apiece of art produced on the anonymous and phenomenal surfaces of the city ?Is the comparison between the body of a human being and the corpse of a city, fortuitous ? Isthis reduction of the man to the wall, metaphorically speaking, constitutive of human relationships ?Real, fictional ? Relative ?How can art form in the emergency a historical view and collective, without distance ?
173

Identité en suspens et Métamorphose dans Garçons de cristal de Bai Xian-Yong, Espèces de Ying Chen et Middlesex de Jeffrey Eugenides / Identity in suspense and Metamorphose in Cristal boy of Bai Xian-Yong, Espèces of Ying Chen and Middlesex of Jeffrey Eugenides

Hung, Shiau-Ting 17 December 2016 (has links)
Cette thèse a pour objet la question de l’identité dans les romans suivants : Garçons de cristal de Bai Xian-Yong, Middlesex de Jeffrey Eugenides, Espèces de Ying Chen. La recherche interroge l’opposition entre identité initiale et celle en rupture par rapport à la norme familiale, sociale et politique dans des contextes romanesques différents. Cette opposition apparaît comme le lieu propre de l’identité en suspens et constitue les enjeux de la métamorphose. Quels sont les facteurs qui contraignent les personnages à se métamorphoser et à s’exiler ? Comment le rapport à soi, confronté à la crise identitaire, est-il évoqué dans ces romans à la première personne ?Dans ces trois romans, l’homosexualité, l’hermaphrodisme, la transformation en animal provoquent la mise en suspens de l’identité et l’exil des personnages. La métamorphose effective ou métaphorique met à l’épreuve le sentiment de l'identité, le rapport à soi et à autrui. Mais la métamorphose établit aussi des ponts grâce auxquels les personnages des trois textes pourront, à des degrés divers, se rejoindre eux-mêmes. / The subject of this thesis is the question of identity in the following novels: Bai Xian-Yong’s Cristal Boys, Jeffrey Eugenides’ Middlesex, and Ying Chen’s Espèces. This research interrogates the opposition between the initial identity and that in rupture concerning the familial, social, and political norm in three different contexts. Such opposition seems to be the place proper to the identity in suspense and constitutes the issues about metamorphosis. What are the factors constraining the characters to metamorphosis and exile? How does the connection to self confront the crisis of identity, is it evoked in these novels in the first-person narrative?In these three novels, the homosexuality, the hermaphrodisme, and the transformation to animal provoke the suspense of identity and the exile of the characters. The effective or metaphoric metamorphosis proves the sense of the identity, the connection of the self and the other. Meanwhile, the metamorphosis establishes the bridges upon which the characters in the three novels could join each other to varying extents.
174

Multiplexed matrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI) biomarker discovery

Luehr, Teesha Crystal 22 December 2017 (has links)
The work presented herein is a method optimization for biomolecule detection and identification using Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging (MALDI-MSI). MALDI-MSI is a unique form of mass spectrometry that is highly multiplexed; it can simultaneously retain location information of the mass of multiple ions, allowing for correlation of morphology or pathology to reconstructed ion heat maps. There were three main objectives for the research - 1) A method optimization of sample preparation techniques for bottom-up proteomic MALDI-MSI was performed. This included the optimization of tissue wash steps, trypsin digestion incubation times, and matrix deposition techniques. The results included identifying the appropriate pH for the wash steps to optimize trypsin digestion, an overnight trypsin incubation to allow for complete digestion, and the inclusion of MCAEF – Matrix Coating Assisted by an Electric Field – during matrix coating for enhanced spectra. 2) An unbiased statistical data processing workflow for simultaneous processing of multiple datasets was performed. This was done using a thyroid hormone treated tadpole dataset to gain insight into the metabolism of anuran metamorphosis. Results found included a finalized data processing workflow that detected 5000 metabolite features from five organs were detected in pre-metamorphic tadpoles. Of these detected metabolites, 136 were significantly affected upon exposure to thyroid hormone and 64 metabolites were putatively identified. 3) A sample preparation technique for metabolomic analysis of formalin-fixed paraffin embedded (FFPE) colorectal liver metastasis samples was performed. Results included the importance of using a high mass resolution mass spectrometer while emphasizing more appropriate use of fresh-frozen tissue sections for metabolomic analysis. / Graduate
175

Les êtres fantastiques dans les contes et légendes de Théodor Vernaleken : étude comparative / Fantastic creatures in Theodor Vernaleken's tales and legends : Comparative Study

Yanez, Séverine 30 April 2011 (has links)
« Il était une fois »… un professeur autrichien, Theodor Vernaleken, qui souhaitait diffuser les récits populaires et coutumes traditionnelles des régions alpines. Ce « Grimm autrichien » les restitue si fidèlement dans ses Contes des Alpes pour les enfants et le foyer et ses Légendes des Alpes qu’il adopte la forme dialectale. Pédagogue émérite, il annote ses récits de nombreuses remarques explicatives rendant ainsi ces témoignages accessibles. Le conte est un récit se déroulant « autrefois » « dans une contrée lointaine ». Les êtres fantastiques surgissent tout naturellement au moment opportun, pour permettre ou empêcher le héros de vivre heureux et d’avoir beaucoup d’enfants. Pour sa part, la légende vise à être crue. Dans ces contes et légendes, les habitants ou un membre de la communauté villageoise ont vu de leurs propres yeux, dans leur village, des êtres surnaturels. Ils nous racontent leur étonnement, leur peur découlant de leur confrontation à cet autre monde peuplé de démons. C’est ainsi qu’apparaissent des homoncules, des géants, des dragons et autres animaux fantastiques, qui parlent, se transforment, etc. L’homme est également confronté à des protagonistes démonologiques tels que sorcières, diables et revenants. Celui qui a transgressé les interdits ne pourra échapper à son destin, tel est le message de ces récits exemplaires et instructifs. Jusqu’à présent, aucune étude exhaustive, ni classification de ce genre littéraire n’a été réalisée. Ainsi, cette étude analysera, par une approche comparative, les récits démonologiques à travers l’étude des êtres fantastiques des textes rassemblés par Theodor Vernaleken. / “Once upon a time”… an austrian professor, Theodor Vernaleken, wanted to spread popular stories and traditional uses from the alpine areas. This “Austrian Grimm” restores them in his books Tales From the Alps for children and home and Legends from the Alps so faithfully that he writes them in dialect form. Highly skilled teacher, he writes lots of explicative notes on his stories making them understandable. A tale is a story, which takes place “a long time ago” “in a far faraway country”. Fantastic creatures appear quite naturally at the right time to allow the heroes to live happy and have lots of children or to prevent it to happen. As for it the legend aims to be believed. In these tales and legends inhabitants or a member of the village community have really seen supernatural creatures in their village. They tell us about their amazement, their fear from the confrontation with this other world populated with daemons. So dwarfs, giants, drakes and other fantastic animals and so on appear, speak and are completely transformed. Humans are also confronting demonologic protagonists such as witches, devils and ghosts. Who transgresses the interdicts cannot escape from his fate. That is the message of these exemplary and instructive stories. Up to now, no exhaustive survey or classification of this literary genre has been carried out. So, this work will analyse demonologic stories in a comparative way through the study of fantastic creatures in texts gathered by Theodor Vernaleken.
176

O futuro do corpo: tecnociência, pirataria e metamorfose

Duarte, Bárbara Nascimento 06 March 2015 (has links)
Submitted by Renata Lopes (renatasil82@gmail.com) on 2015-12-03T11:17:01Z No. of bitstreams: 1 barbaranascimentoduarte.pdf: 2112433 bytes, checksum: fce94787e42900386c7986b66a5b6644 (MD5) / Made available in DSpace on 2015-12-03T11:17:01Z (GMT). No. of bitstreams: 1 barbaranascimentoduarte.pdf: 2112433 bytes, checksum: fce94787e42900386c7986b66a5b6644 (MD5) Previous issue date: 2015-03-06 / CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / O corpo humano está agora enredado numa trama muito particular, característica de nossa era tecnocientífica: seu valor e seu destino estão submetidos aos processos racionais e às novas técnicas que são continuamente desenvolvidas nos laboratórios. A partir de uma visão algo utópica, muito além de uma simples materialidade orgânica, as fronteiras da corporalidade estão assim sendo radicalmente questionadas e transformadas. E, neste passo, os conhecimentos científicos e sua mística transbordam seus campos estritos de aplicação, para alcançar e mobilizar o desejo e a vontade de indivíduos e do público em geral. Em nosso trabalho, buscamos investigar a relação entre as experiências de laboratório e aquilo que identificamos como o panorama underground de tecnologização do corpo. Procuramos assim circunscrever certas modificações corporais extremas, definidas como body hacktivism, body hacking ou pirataria do corpo, que se fundam numa perspectiva lúdica e exploratória, realizadas por amadores com o propósito de ampliar os limites sensoriais do homem. Tal reapropriação individual das tecnologias se converte, então, em inovações e em práticas inusitadas, por exemplo: implantes de microchips RFID, de magnetos, de vibradores genitais ou placas de titânio para substituir a pele, e mesmo próteses robóticas feitas com peças de Lego. A pesquisa de campo foi empreendida entre 2011 e 2013, em contato com vários praticantes selecionados na Europa, nos Estados Unidos e no Brasil. A metodologia qualitativa privilegiou a aplicação de entrevistas semiestruturadas e visitas a lojas de tatuagem/piercing, hotéis, eventos e seminários. O objetivo desta tese é, portanto, compreender qual corpo os body hackers constroem para si e projetam para os outros, explorando assim suas concepções acerca do sujeito humano. O argumento principal é de que os body hackers, por suas palavras e suas práticas, reverberam a mesma ontologia radical do individualismo moderno, ao tomar o indivíduo como a unidade social básica e a apropriação de seu próprio corpo como a relação fundamental. A simbiose do corpo com artefatos variados, que as novas tecnologias possibilitam, faculta ao indivíduo percepções exclusivas, nas quais os elementos inorgânicos se tornam não apenas mediadores da experiência pessoal, mas uma extensão ou parte articulada de si mesmo. Em suma, a tecnologia inserida no corpo além de modificá-lo, também transforma a forma de perceber, de estar e de ser-no-mundo. A pirataria do corpo, enfim, chama a atenção para uma realidade insofismável: se um dia a natureza concedeu aos seres humanos um corpo, para tê-lo, atualmente, é preciso superar o simples evento biológico e buscar incansavelmente o seu aperfeiçoamento, a quimera extraordinária de uma perfeição e de uma imortalidade vindoura. / In the present technoscientific era, the body is involved in a particular scheme: its value is directly related to its rational and technical production in scientific laboratories, where a utopian vision of corporeality has been delineated. In these, its boundaries are radically challenged and transformed, moving beyond organic materiality. Nevertheless, scientific development goes beyond its pre-set field of action, and its resulting knowledge touches society in a singular way. In our investigation, we seek to discover the relationships between laboratory experiments and what we identify as the underground scene of body technologization. Within it, we circumscribe extreme body modifications, defined as body hacktivism and body hacking, which stand for a playful and exploratory perspective, performed by scientifically-inclined amateurs whose purpose consists of amplifying a person’s sensory limits. This individual reappropriation of technologies turns out in innovations, including RFID microchip and magnetic implants, genital vibrators, engineering of titanium skin interfaces, and even robotic prostheses made with Legos. Through an empirical study undertaken from 2011 through 2013, we conducted participant observations with a number of privileged proponents of these practices in Europe, in the United States and in Brazil. Our methodology was qualitative, notably through the application of semi-directive interviews. The research focused on tattoo/piercing shops, hotels, body modification events and seminars. Our problem is to understand which body the body hackers build and design, and to view the conception of the human subject. Our principal argument is that body hackers are on record for self-production in a radical individualism that has, as a privileged analytical unit, the individual (and its growing individualization) and the self-ownership of the body as its fundamental measures. Then, the symbiosis of the individual with the environment, through new technologies, creates a distinctive perception in which an inorganic element becomes the mediator of the experience of the self and of the other. Lastly, they come together in such a way that the individual becomes a unity with it. In short, these embedded technologies not only modify the body, but also change the way of perceiving, living, and being in the world. The body hacking draws our attention to the understanding of a scientific reality: if one day nature granted man a body, to have currently, it is fundamental to overcoming this biological event, endlessly seeking its improvement, until the day that man will attain the chimera of perfection and immortality.
177

Aspectos bioquímicos da hemolinfa e do casulo coletivo de Rhynchosciara americana / Biochemical aspects of hemolymph and cocoon collective Rhynchosciara Americana

Walter Ribeiro Terra 14 June 1972 (has links)
Os resultados obtidos nesta tese podem ser distribuídos em três grupos: composição química da hemolinfa e do casulo coletivo e determinação química de alguns componentes principais do corpo gorduroso e túbulos de Malpighi ao longo do desenvolvimento. Os principais resultados referentes à química da hemolinfa de larvas maduras são: 1) A hemolinfa possui uma densidade 1,043, pH = 7,27, osmolaridade = 216 miliosmoles e corresponde a 37% do pêso-úmido do animal e 26% de seu pêso-sêco. A hemolinfa não se coagula e possui um volume de células correspondente a 0,3% de seu volume total. 2) A análise química realizada deu conta de 88% do peso-sêco total da hemolinfa e revelou que entre os componentes presentes mais importantes em massa estão as proteínas, seguidas dos aminoácidos livres, enquanto que os osmóticamente mais ativos são os aminoácidos livres seguido de Mg++ e Na+. Entre os aminoácidos é notável a presença de ornitina e cistationina em concentrações relativamente elevadas e a ausência, mesmo em traços, de cisteína e/ou cistina e citrulina. 3) Os peptídeos ocorrem em concentrações elevadas, mas em pequeno número, e são compostos de 2 a 3 resíduos de aminoácidos em média; o mais abundante dos quais deve ser um dipeptídeo de histidina e ácido aspártico. 4) Citrato é o ânion mais importante da hemolinfa, seguido dos fosfatos orgânicos, enquanto que trealose é o principal carboidrato presente. 5) Existem pelo menos 6 carotenóides ligados de forma não covalente a proteínas da hemolinfa e uma cromoglicoproteína, de côr amarelo-limão, fluorescente, de natureza desconhecida. Os carotenóides mais importantes quantitativamente são: β-caroteno e um similar ao astaceno. A composição em massa do casulo coletivo na véspera da muda pupal é a seguinte, em números inteiros: 44% de CaCO3; 34% de proteínas e 10% de carboidratos, ambos insolúveis em todos solventes utilizados (SDS 10%, uréia 6M, ácido fórmico 50%, HCl 2N, KOH 1M e Na HCO3 1M); 10% de material hidrossolúvel 4% de cinzas não identificadas. O material hidrossolúvel foi parcialmente identificado como: proteína (4%), carboidratos (2%), enquanto que 4% ainda permanece desconhecido. O correlacionamento da análise química da hemolinfa, casulo, túbulos de Malpighi e corpo gorduroso ao longo do desenvolvimento, possibilitou ainda as seguintes conclusões: 1) A fração insolúvel do casulo (proteínas e carboidratos) corresponde à sêda secretada pelas glândulas salivares da larva, enquanto que o CaCO3 presente provém dos túbulos de Malpighi. 2) As proteínas do casulo devem originar-se, pelo menos em parte, das proteínas da hemolinfa, enquanto que seus carboidratos devem provir do glicogênio do corpo gorduroso. Os resultados são considerados em têrmos de seus possíveis significados metabólicos e eventualmente fisiológicos. Ênfase é dada na discussão do papel metabólico dos componentes orgânicos e inorgânicos da hemolinfa, assim como dos mecanismos de secreção da sêda e CaCO3 e sua possível regulação hormonal. / The results of this thesis are concerned to three main lines of research: the chemical composition of the hemolymph, of the communal cocoon, and the chemical determination of some components in the rat body and Malpighian tubules along larval development. The chief results on the hemolymph chemistry of mature larvae are: 1) The hemolymph has a density = 1.043, pH = 7.27, osmolarity = 2l6 miliosmols and corresponds to 37% of the larva (Wet-Weight) or to 26% of the larva (dry weight). The hemolymph does not clott and the volume of the hemocytes is 0.3% of blood total volume. 2) The chemical analysis dealt with 88% (dry-weight) of the hemolymph and showed that proteins are the most important component in mass, while free amino acids, Mg++ and Na+ are the most osmotically active substances. Among the amino acids is remarkable the titres of ornithine and cystathionine, and the complete absence of cysteine and/or cystine and citrulline. 3) There are few peptides, but present in high titres. They are built of two to three amino acids residues, and the most concentrated of them must be a dipeptide of histidine and aspartic acid. 4) Citrate and organic phosphates are the most important anions in the hemolymph. Trehalose is the chief carbohydrate present. 5) There are at least 6 non-covalentely protein-bound carotenoids and one lemon-yellow, fluorescent chromoglycoprotein of unknown nature. The chemical composition of the communal cocoon of R. americana expressed in percentage of its total dry weigth (numbers rounded to the nearest unity) are: 44% of CaCO3; 34% of proteins and 10% of carbohydrates both insoluble in all solvents used (10% SDS, 6M urea, 50% formic acid, 2N HCl, 1M KOH and 1M NaHCO3 ); 10% of water soluble material and 4% of unknown nature. The water soluble material was identified in part as: protein (4%) and carbohydrates (2%), while 4% remained unknown. The interrelationship among the results of the chemical analysis of the hemolymph, cocoon, Malpighian tubules and fat body during larval development was used to draw the conclusions: 1) The insoluble fraction of the cocoon proteins and carbohydrates) corresponds to the silk produced by the larval salivary glands, while CaCO3 comes from Malpighian tubules. 2) The cocoon proteins must come, at least in part, from the hemolymph proteins, while its carbohydrates must come from the fat body glycogen. The results are discussed in terms of its possible metabolic and eventually physiological meanings. Emphasis is given in the discussion of the metabolic role of the inorganic and organic components of the hemolymph, as yet in the the mechanisms of the silk secretion and CaCO3 deposition and their possible hormonal regulation.
178

Music as a Woven Narrative to an Absurd Tale in Act One of The Metamorphosis

Poovey, Christopher, 1993- 05 1900 (has links)
Act one of The Metamorphosis is based on the novella by Franza Kafka of the same title. In the writing of the act, George Benjamin's Into the Little Hill and Oliver Knussen's Where the Wild Things Are provide a model of using musical material as a storytelling device. Benjamin emphasizes the parallel nature of Crimp's text through the manipulation of similar music between the acts. Knussen uses form and color to emphasize Max's childlike energy and his desire to return home. In act one of The Metamorphosis these approaches are combined to enhance Kafka's absurd narrative through a rapid collage of texture and form that is influenced by both events and characters in the opera.
179

Cross-Talk Between Estrogen and Thyroid Hormones During Amphibian Development

Duarte Guterman, Paula January 2011 (has links)
It is generally thought that in amphibians, thyroid hormones (THs) regulate metamorphosis, while sex steroids (estrogens and androgens) regulate gonadal differentiation. However, inhibition of TH synthesis in frogs alters gonadal differentiation, suggesting instead that these two endocrine axes interact during development. Specifically, THs may be involved in male development, while estrogens may inhibit tadpole metamorphosis. However, we do not currently know the mechanisms that account for these interactions, let alone how such mechanisms may differ between species. To develop and test new hypotheses on the roles of sex steroids and THs, I first examined transcriptional profiles (mRNA) of enzymes and receptors related to sex steroids and THs during embryogenesis and metamorphosis in Silurana tropicalis. Tadpoles were exposed to either an estrogen synthesis inhibitor (fadrozole) or TH (triiodothyronine, T3) during early larval or tadpole development. Acute exposures of S. tropicalis to fadrozole or T3 during early development resulted in increased expression of androgen- and TH-related genes in whole body larvae, while chronic exposure to fadrozole during metamorphosis affected gonadal differentiation but did not affect tadpole development. On the other hand, acute exposure to T3 during metamorphosis increased the expression of androgen-related transcripts both in the brain and gonad. In S. tropicalis, the results suggested that cross-talk is primarily in one direction (i.e., effect of THs on the reproductive axis) with a strong relationship between TH and androgen status. Lastly, I established developmental transcript profiles and investigated T3 regulation of brain and gonad transcripts in Engystomops pustulosus. I then compared these results with S. tropicalis and an earlier study in Lithobates pipiens. While each species developed with similar profiles, they differed in their response to T3. Exposure to T3 resulted in either an increase in androgen-related genes (S. tropicalis) or a decrease in estrogen-related genes (E. pustulosus and L. pipiens). In conclusion, these data demonstrated that cross-talk mechanisms differ among these three evolutionary separate species, but in all cases, T3 appears to affect the balance of sex steroids, stimulating the androgen system and providing potential mechanisms of the masculinising effects of THs. These results will contribute to understanding the mechanisms of hormone interactions and their evolutionary basis in frogs.
180

Desperate Coral Larvae? Behavioral Responses to Settlement Cues in Aging Agaricia agaricites Larvae

Fulmore, Helena Sasha 24 July 2019 (has links)
The global stressors of ocean warming and acidification, as well as local stressors such as eutrophication, overfishing, and coastal construction, have all contributed to the severe decline in coral populations worldwide. Recovery of coral reefs depends partly on recruitment, which relies on the response of larvae to settlement cues indicative of habitat quality; however, it remains unclear whether recruitment in disturbed areas will be compromised. Specifically, as reefs become more disturbed and dominated by macroalgae, it is important to understand larval behavior in response to changes in habitat quality. In this study, we first assessed the settlement success of newly released Agaricia agariciteslarvae in response to several settlement cues, including temperature and water movement. Then, to test the Desperate Larva Hypothesis, the ability of larvae of different ages (0-7 days) to settle and discriminate between inducing and inhibitory settlement cues was assessed. Newly released larvae displayed a stronger preference for settling on crustose coralline algae (93%) than on ceramic plates in macroalgae- (30%) or conspecific-treated seawater (5%), or filtered seawater (13%) (control). Older larvae became progressively less discriminatory of settlement cues, settling even in response to inhibitory cues. This confirms that, although the absence of good settlement cues initially deters settlement, larvae become desperate as they become older and settle even on unfavorable substrates, thus contributing to recruitment in poor quality habitats.

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