Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / This research, linked to the Teaching Post-Graduating Course, Arts Educational field, has been developed in a third (3rd) grade class of the Antônio Alves Ramos school, at the city of Santa Maria, RS. Aimed to know and analyze the under constructing creative process of the Initial Years children, providing time and space to the poetic action-experience, in the interacting with the education of the sensorial aspects. For that, articulates a dialogue with voices and ideas of Bachelard (1988, 1989, 1994), Richter (2005), Duarte Jr. (2001), Martins(1998), Maturana and Varela (2002) and Barbosa (2001, 2002). The methodology used in the research was based in the qualitative nature principles by the action-research. Presents itself as participant research, sustained by experiences of art poetics and fruition of daily school experience, emphasizing the imaginary, the creative process and dimension of being a person, not just the final artistic product. The instruments used for gathering data for this research were participative and free observation, field diary and portfolio. For that, in the creative process of children visual poetics, became obvious that the body carries a history - body time - and we can not teach them how to see, imagine, think or act like the adults. The act of creation demanded differentiated times, since each child understood the world in a different way, in their inexperience - another time aspect - admired, enamored, wondered, curious. The under constructing visual poetics allow with pleasure, internal discoveries which feed the person essence in a way to be able to feel, touch, mix, stick together, shape, plot, collect. Therefore, work with art is to believe in the tuning between pleasure and feeling, emotion and thought to construct a world of significance and significants. A world of colors, words, thoughts and actions, where art and knowledge interact on the poetic work and collaborate significantly in childish formation. / Esta pesquisa vinculada ao Curso de Pós-Graduação em Educação, Linha de Pesquisa em Educação e Artes, foi desenvolvida com uma turma de 3ª série da Escola Antônio Alves Ramos, na cidade de Santa Maria-RS. Objetivou conhecer e analisar o percurso criativo das poéticas visuais em construção de crianças dos Anos Iniciais, proporcionando tempo e espaço para experenciAÇÃO poética, na interação com a educação (do) sensível. Para tanto, articula um diálogo com as vozes e idéias de Bachelard (1988, 1989, 1994), Richter (2005), Duarte Jr.(2001), Martins(1998), Maturana e Varela (2002) e Barbosa (2001, 2002). A metodologia utilizada na pesquisa tem por base os princípios de natureza qualitativa através da pesquisa-ação. Apresentase como pesquisa participante, sustentada na experiência para poetizar e fruir arte no cotidiano escolar, enfatizando o imaginário, o processo poético e as dimensões de pessoalidade, e não apenas o resultado plástico obtido. Os instrumentos de coleta de dados utilizados nesta pesquisa foram: observação livre e participante, diário de campo e portfólio. Para tanto, nos percursos criadores das poéticas visuais das crianças, tornou-se evidente que o corpo traz uma história um tempo corporalizado e que não podemos ensina-las a ver e muito menos a imaginar, pensar e agir como nós adultos. Os fazeres exigiam tempos diferenciados, já que cada criança abordava o mundo de modo diferente, em sua inexperiência outra temporalidade o abordavam encantadas, admiradas, espantadas, instigantes. As poéticas visuais em construção permitiram prazerosamente, descobertas internas que nutrem a essência do sujeito de forma a poder sentir, tocar, misturar, agregar, colar, juntar, modelar, esculpir, traçar. Por isso, trabalhar com a arte é apostar na sintonia do prazer com o sentimento, o afeto e o pensamento para a construção de um mundo de significado e significantes. Um mundo de cores, palavras, pensamentos e ações, onde arte e cognição interagem no trabalho poético e colaboram significativamente na formação infantil.

La métamorphose est une étape cruciale du cycle de vie de beaucoup de métazoaires. Elle est définie comme la transition d’une larve en un juvénile, souvent accompagnée de changements drastiques de morphologie, physiologie et de niche écologique. Le rôle des hormones thyroïdiennes a été mis en évidence dans la métamorphose des amphibiens, mais aussi de nombreux autres chordés comme certains poissons téléostéens ou l'amphioxus, suggérant que ce système était déjà présent et impliqué dans la métamorphose chez l'ancêtre commun de tous les chordés.Nous avons étudié le lien entre hormones thyroïdiennes et métamorphose selon deux axes. Premièrement, nous avons étudié la coordination entre la métamorphose et le recrutement larvaire, chez le chirurgien bagnard Acanthurus triostegus. Ce travail nous a permis de mieux comprendre le rôle de l’hormone thyroïdienne comme signal déclencheur d'une transition écologique importante. Dans le second axe de travail nous avons examiné l’origine de la signalisation thyroïdienne. Chez l’annélide Platynereis dumerili, nous avons identifié un récepteur fonctionnel des hormones et un rôle de l’hormone thyroïdienne dans son développement. Cela qui nous permet de démontrer que la signalisation thyroïdienne était présente à l’origine des bilateriens. Nous avons également mis en évidence un rôle des hormones thyroïdiennes dans le développement de cette espèce. Enfin dans le troisième axe nous nous sommes penchés sur l’origine de la synthèse de l’hormone thyroïdienne en retraçant l’évolution de la thyroglobuline, la protéine nécessaire à la production d’hormone chez les vertébrés. Son absence dans les autres taxons, alors que les dérivés de l’hormone y ont un rôle biologique, pose la question des mécanismes ancestraux de synthèse de ces hormones.Ces travaux explorent l’évolution de la signalisation thyroïdienne et proposent d’aborder la question du lien avec la métamorphose d’un point de vue évolutif et non-seulement développemental, afin de mieux comprendre la diversité des métamorphoses observées dans le monde animal. / Metamorphosis is a critical life step of many metazoans. It is defined as the transition between a larva and a juvenile. It comes with major changes of morphology, physiology and ecology. The role of thyroid hormone has been proven in the metamorphosis of amphibians but also in many other chordates such as teleost fishes or the amphioxus. This suggests that this system was functional and involved in the metamorphosis of the common ancestor of all chordates.We studied the link between thyroid hormones and metamorphosis according to two axes. First, we studied the coordination between metamorphosis and the larval colonization, using the convicted surgeon fish Acanthurus triostegus as a model. This work allowed us to better understand the role of thyroid hormones as a trigger signal of a major ecological transition. On the second axis, we investigated the origin of thyroid hormone signalization. In the annelid Platynereis dumerilii, we identified a functional thyroid hormone receptor and a role of TH in its development. This proves that thyroid hormone signaling was present at the basis of bilaterians. We also assessed the question of the origin of thyroid hormone synthesis by tracing back the evolution of the thyroglobulin, the protein mandatory for thyroid hormone synthesis in vertebrates. It absence in the other taxa, whereas thyroid hormone derivatives have a biological role, asks the question of the ancestral mechanisms of thyroid hormone synthesis.These works investigate the evolution of the thyroid hormone signalization and suggest to tackle the question of the link with metamorphosis from an evolutionary perspective, and not only from a developmental one, in order to better understand the diversity of metamorphosis overserved in the animal kingdom.

Amphibians develop in aquatic environments where they are very susceptible to the effects of pesticides and other environmental contaminants. Glyphosate-based herbicides are widely used and have been shown to affect survival and development of tadpoles under laboratory conditions. The goal my thesis is to determine if agriculturally relevant exposure to Roundup WeatherMax®, a herbicide formulation containing the potassium salt of glyphosate and an undisclosed surfactant, influences the survival and development of wood frogs tadpoles (Lithobates sylvaticus) under both laboratory and field conditions. In the field, experimental wetlands were divided in half using an impermeable curtain so that each wetland contained a treatment and control side. Tadpoles were exposed to two pulses of this herbicide at environmentally realistic concentration (ERC, 0.21 mg acid equivalent (a.e.)/L) and predicted environmental concentrations (PEC, 2.89 mg a.e./L), after which survival, growth, development, and expression of genes involved in metamorphosis were measured. Results indicate that exposure to the PEC is extremely toxic to tadpoles under laboratory conditions but not under field conditions. Results from both experimental conditions show sublethal effects on growth and development, and demonstrate that ERC of glyphosate-based herbicides have the potential to alter hormonal responses during metamorphosis. My secondary objectives were to compare the effects of Roundup WeatherMax® to the well-studied Vision® formulation (containing the isopropylamine (IPA) salt of glyphosate and POEA), and to determine which ingredient(s) are responsible for the sublethal effects on development. Survival, growth and gene expression results indicate that Roundup WeatherMax® has greater toxicity than Vision® formulation. Contrary to my prediction, results suggest that, under realistic exposure scenarios, POEA is not the sole ingredient responsible for the observed developmental effects. However, my results demonstrate that chronic exposure to the POEA surfactant at the PEC (1.43 mg/L) is extremely toxic to wood frog tadpoles in laboratory. As part of the Long-term Experimental Wetlands Area (LEWA) project, this research contributes to overall knowledge of the impacts of glyphosate-based herbicides on aquatic communities.

L’œuvre romanesque d’Amin Maalouf propose un traitement particulier du personnage qui dépasse le cadre habituel de son analyse. Objet de toutes les attentions mais aussi de tous les débordements, le personnage reflète l’ensemble des problématiques qui opèrent à l’intérieur de la fiction. On trouve ainsi dans les romans d’Amin Maalouf une contamination, voire même une dissémination, du personnage vers d’autres instances. Ces instances le prolongent en peuplant, à leur tour, le roman et en se proposant d’y laisser une empreinte poétique.Les métamorphoses et les mutations successives, dont le roman fait l’objet, viennent relayer sa présence, lui octroyant une dimension nouvelle. En multipliant ses appartenances et ses origines, la fiction propose un voyage à travers les multiples facettes du personnage qui lui permettent de renouer avec sa nature originelle. Tourné vers le mouvement, aspirant à se redéfinir au travers des autres instances textuelles, le personnage s’impose comme un véritable agent romanesque. La thèse propose ainsi de révéler précisément les tenants de ces métamorphoses et de ces mutations romanesques, afin de mettre en lumière les infinis prolongements qui concourent à l’élaboration d’une poétique singulière. / Amin Maalouf’s novels offer a special treatment of the character beyond the usual scope of its analysis. The object of all attention and excesses, the character reflects all issues operating within the fiction. Thus we find in Amin Maalouf’s fiction a sort of contamination, even a release of the character to other authorities. Throughout the novel these authorities extend adopt traits of the main character as personifications. They extend its presence their presence, occupy the fiction in their turn and try to leave a poetic mark.Metamorphoses and successive mutations, of which the novel is the subject, just relay its presence, giving it a new dimension. Increasing its appurtenances and its origins, fiction offers a journey through the many facets of character that allow it to return to its original nature. Facing movement, aspiring to redefine itself through other textual authorities, the character stands out as a true romantic agent.The thesis proposes to reveal precisely the proponents of these metamorphosis and mutations of fictions to highlight the infinite extensions that contribute to the development of a singular poetic.

Au cours de la métamorphose, les amphibiens subissent une réorganisation complète de leur anatomie et de leur physiologie. Chez Xenopus laevis le système locomoteur est un des plus affecté au cours de cette phase développementale, l’animal passant d’une nage ondulatoire à une nage appendiculaire. Cette transformation du mode locomoteur implique une réorganisation du réseau locomoteur central. Dans une première étude, nous avons mis en évidence que les muscles axiaux s’activent de manière bilatéralement alternée chez le têtard alors que les muscles équivalents chez l’adulte s’activent de manière synchrone au cours de la nage. Nous avons montré que ce nouveau patron d’activation musculaire, accompagné d’une synchronisation avec les muscles appendiculaires extenseurs, reposent principalement sur la mise en place de nouvelles projections propriospinales lombo-thoraciques. Ces résultats suggèrent l’existence d’un contrôle postural proactif au cours de la locomotion, reposant directement sur le CPG des membres postérieurs. Dans une deuxième étude, nous nous sommes intéressés à l’influence d’un déséquilibre des afférences vestibulaires sur le développement du réseau locomoteur spinal au cours de la métamorphose. Pour cela nous avons réalisé une suppression unilatérale des organes vestibulaires avant ou après la métamorphose. Dans les deux cas, cette lésion aigue génère d’importants troubles locomoteurs et posturaux. Nous avons montré que la lésion chronique au cours de la métamorphose entraîne une modification ipsi-lésionnelle du développement du réseau locomoteur lombo-thoracique, de manière concomitante à une compensation comportementale. De façon intéressante, cette plasticité développementale ainsi que la compensation des troubles locomoteurs sont absentes chez les animaux lésés au stade adulte. Ces résultats suggèrent que les informations sensorielles sont un facteur déterminant pour le développement du réseau locomoteur spinal. Enfin, dans une troisième étude, nous avons analysé le développement du réseau locomoteur supra-spinal et en particulier les propriétés de déclenchement et de contrôle de la région locomotrice mésencéphalique (MLR). Nous avons mis en évidence l’existence fonctionnelle des deux noyaux de cette structure, le noyau pédonculopontin (PPN) et le noyau latérodorsal du tegmentum (LDT) tout au long de la métamorphose du xénope, ainsi qu’une fréquence d’activation optimale de 10-20 Hz pour le PPN. / Throughout the course of metamorphosis, amphibians undergo a complete anatomical and physiological reorganization. In Xenopus laevis, the locomotor system is one of the most affected during this developmental phase where the animal passes from undulatory swimming to limb-based propulsion. This transformation implies a parallel reorganization of the central locomotor network. In an initial study we showed that axial muscles which are activated in bilateral alternation in tadpoles mature to dorsal muscles that are synchronously active during adult locomotion. We found that this new pattern, accompanied by coordination of dorsal and hindlimb muscle activities, is principally sustained by the development of new propriospinal lumbo-thoracic projections, suggesting proactive postural control coming from the hindlimb CPG during ongoing locomotion. In a second study, we examined the influence of disequilibrium in vestibular inputs on the metamorphic development of the spinal locomotor network. To induce this sensory asymmetry we performed unilateral removal of vestibular end organs either before or after metamorphosis. Acutely, in both cases, the lesion induced dramatic postural and locomotor changes. Chronically, the lesion altered the metamorphic development of the lumbo-thoracic network on the lesioned side, concomitantly with compensation for locomotor defects. Interestingly, animals lesioned after metamorphosis neither compensated nor expressed this developmental spinal plasticity. Altogether, these results suggest that descending sensory inputs are crucial cues for the development of the spinal locomotor network. Finally, we studied the metamorphic development of the supra-spinal network, focusing our attention on the locomotor triggering and control properties of the mesencephalic locomotor region (MLR). We showed that both subparts of this structure, the laterodorsal tegmentum (LDT) and the pedunculopontine (PPN) nuclei, are present and functional during the entire period of metamorphosis and that the PPN has an optimal activation frequency of 10-20 Hz.

Le fard est une composition dont l’application sur la peau donne à celle-ci plus d’éclat ou masque un défaut physique. Accusé de tromper, instrument futile ou diabolique auquel fut comparée la peinture, le fard se définit par sa fonction mais ne s’y réduit pas. L’observation de trois vidéos permet d’étudier le fard en tant qu’il est matière colorée et conduit à déterminer ses propriétés spécifiques et les possibilités plastiques qu’elles véhiculent.Cette recherche vise à établir les modalités d’une relation entre le fard, la couleur, et le corps support au travers d’expériences plastiques filmées pour le caractériser ensuite comme médium à partir d’une pratique personnelle. / Makeup is a composition which when applied to the skin gives it more brightness or hides a physical defect. Accused of cheating, a futile or diabolical instrument, which paint has been compared, make-up is defined by its function but has lost nothing through this.The plastic arts experience allows study of make-up because it is colored and this helps determine its specific properties and plastic possibilities.This research aims to establish the details of a relationship between makeup, color and the body, using several videos to characterize it as a medium based on personal practice.

Triclosan (TCS) and triclocarban (TCC) are antimicrobials found in U.S. surface waters. This dissertation assessed the effects of TCS and TCC on early development and investigated their potential to bioaccumulate using Xenopus laevis as a model. The effects of TCS on metamorphosis were also investigated. For 0-week tadpoles, LC50 values for TCS and TCC were 0.87 mg/L and 4.22 mg/L, respectively, and both compounds caused a significant stunting of growth. For 4-week tadpoles, the LC50 values for TCS and TCC were 0.22 mg/L and 0.066 mg/L; and for 8-week tadpoles, the LC50 values were 0.46 mg/L and 0.13 mg/L. Both compounds accumulated in Xenopus. For TCS, wet weight bioaccumulation factors (BAFs) for 0-, 4- and 8-week old tadpoles were 23.6x, 1350x and 143x, respectively. Lipid weight BAFs were 83.5x, 19792x and 8548x. For TCC, wet weight BAFs for 0-, 4- and 8-week old tadpoles were 23.4x, 1156x and 1310x. Lipid weight BAFs were 101x, 8639x and 20942x. For the time-to-metamorphosis study, TCS showed an increase in weight and snout-vent length in all treatments. Exposed tadpoles metamorphosed approximately 10 days sooner than control tadpoles. For the hind limb study, although there was no difference in weight, snout-vent length, or hind limb length, the highest treatment was more developed compared to the control. There were no differences in tail resorption rates between the treatments and controls. At relevant concentrations, neither TCS nor TCC were lethal to Xenopus prior to metamorphosis. Exposure to relatively high doses of both compounds resulted in stunted growth, which would most likely not be evident at lower concentrations. TCS and TCC accumulated in Xenopus, indicating that the compound has the potential to bioaccumulate through trophic levels. Although TCS may increase the rate of metamorphosis in terms of developmental stage, it did not disrupt thyroid function and metamorphosis in regards to limb development and tail resorption.

This thesis deals with translation and interpretation of pseudovergilian epyllion Ciris, which tells a story of traitorous princess of Megara, Scylla, who betrays her father Nísos by cutting off his magical purple lock. With it she surrenders the entire city to the enemy Minos in order to secure his love. Her plan ultimately fails and as a result she is transformed into a brand new bird named the ciris. The first part of the thesis provides a literary-theoretical study of the epyllion based on comparison with the sources of the myth and other latin poems, as it seems as if Ciris was composed by an anonymous young disciple in a late latin cento style but only published in his older age. Some ascribe it to young Virgil or Cornelius Gallus. In the course of the study the following questions will be answered: Is Scylla's transformation a liberation or punishment for her crime? What is the role of nutrix in the epyllion and what is her literary origin? How does the author deal with the weaving metaphore? The second part of the thesis offers a first prosaic translation of Ciris into czech language with a humble commentary where deemed necessary.

This thesis deals with translation and interpretation of pseudovergilian epyllion Ciris, which tells a story of traitorous princess of Megara, Scylla, who betrays her father Nísos by cutting off his magical purple lock. With it she surrenders the entire city to the enemy Minos in order to secure his love. Her plan ultimately fails and as a result she is transformed into a brand new bird named the ciris. The first part of the thesis provides a literary-theoretical study of the epyllion based on comparison with the sources of the myth and other latin poems, as it seems as if Ciris was composed by an anonymous young disciple in a late latin cento style but only published in his older age. Some ascribe it to young Virgil or Cornelius Gallus. In the course of the study the following questions will be answered: Is Scylla's transformation a liberation or punishment for her crime? What is the role of nutrix in the epyllion and what is her literary origin? How does the author deal with the weaving metaphore? The second part of the thesis offers a first prosaic translation of Ciris into czech language with a humble commentary where deemed necessary.

Opus Alchemicum explores the fabrication of “reality” upon imagination, and the affective relation between ideas and matter in the built environment. Like an alchemic experiment, through the manipulation of real facts and their transformation into myth, stories, rituals and objects, the project tries to demonstrate how myths are not just produced but also produce “real” by creating a collective understanding and a pattern of relations, roles and ideas. This project’s attempt is to reveal the mechanisms of reality in an act of analogy. The role of architecture, buildings and objects is investigated in its transfigured correspondent. Myths are both constructed and revealed as the language code of a discourse. The result is a work of alchemy, a product of imagination as a path of understanding. The project starts with traveling to Romania as a study case, in a journey where encounters and empathy win over maps and scheduled visits. What I bring back with me is a series of situations, assemblages, a pattern of history, places, culture and affections belonging to the very present of Romania.These situations are plunged in another larger assemblage, the European one, with Sweden as a partaker. In this country’s desires and metamorphoses we can discover those myths that belong and affect our culture and our spaces.  Opus Alchemicum is a tale about myths, behavior and built environment. About Romania, or somewhere else. About ruins and gold. About invisible values and material affects. About a vanished land, about desire and nostalgia. About displacement, diaspora and costumes. About migration. About a journey and the gas station at the mid of the road. About metamorphoses, gypsy palaces and dowries. About matter, produced, traded and extinguished. About Prussian Blue and honey. About a tower, a fountain and a secret garden. About the alchemic process of making reality out of ideas. / Opus Alchemicum utforskar fabricering av verklighet genom fantasi, den affektiva relationen mellan ide och materia i en bygg omgivning. Ett alkemiskt experiment, genom manipulation av verkliga fakta och deras transformation till myter, berättelser, ritualer och objekt, försöker detta projekt att påvisa hur myter inte bara är producerade utan hur de också producerar en ”verklighet” genom att skapa en kollektiv förståelse och ett mönster av relationer, roller och föreställningar. Projektet försöker att avslöja mekanismerna av verklighet i en handling av analogi. Rollen av arkitektur, byggnader och objekt undersöks i sin förvandlade korrespondens. Myter är både konstruerade och avslöjade genom språkkoden för en diskurs. Resultatet är ett verk av alkemi, en produkt av inbillningsförmåga längst en väg för förståelse. Projektet startar med en resa till Rumänien som studie fall, i en färd där möten och empati segrar över kartor och schemalagda möten. Det jag tog med mig tillbaka var en serie av situationer, samlingar och mönster av historien. Platser, kultur och känslor som representerar det nuvarande Rumänien. Situationer som störtar in till ett större sammanhang i form av det Europeiska med Sverige som deltagare. I detta lands önskningar och metamorfoser kan vi upptäcka de myter som tillhör och påverkar vår kultur och dess rum. Opus Alchemicum är en berättelse om myter, beteenden och byggd omgivning. Om Rumänien eller någon annanstans. Om ruiner och guld. Om osynliga värden och materiell inverkan. Om ett försvunnet land av begär och nostalgi. Om förskjutningar, förskingringar och kostymer. Om migration. Om färder och bensinstationen i mitten av resan. Om metamorfoser, romerska palats och hemgifter. Om materia, producerad, handlad och utsläckt. Om preussiskt blått och honung. Om ett torn en fontän och en hemlig trädgård. Om den alkemiska processen av att skapa verklighet genom idéer.