Ce travail doctoral propose une théorisation enracinée du phénomène de survie locale au sein de la firme multinationale. L'objectif est d'apporter des éléments de réponse à la problématique suivante : quelles sont les stratégies locales élaborées par les sites industriels de multinationales afin de survivre et de se maintenir au sein de la chaîne de valeur de l'entreprise malgré un contexte de globalisation et de rationalisation des coûts de production ? L'étude historique du cas d'IBM Montpellier nous permet d'interpréter le phénomène de survie locale comme résultant d'un processus managérial de maturation de la survie par la transformation. Ce processus se décompose en trois étapes successives : une phase de conformité pendant laquelle les acteurs locaux ressentent peu de pressions exogènes et se contentent d'adopter et d'exécuter les pratiques et les directives globales ; une phase d'opposition qui émerge en réaction à des menaces soudaines et qui consiste à contester certaines logiques globales afin de protéger les acquis locaux ; et une phase de transformation pendant laquelle les acteurs locaux cherchent à anticiper les futures évolutions de la compagnie et à redéfinir les pratiques et les logiques locales afin d'être en mesure d'influencer ou de contourner des décisions jugées menaçantes. La thèse met en exergue le caractère paradoxal du processus stratégique de survie en le situant à l'interface entre résistance et conformité. La démarche étudiée consiste à traduire les transformations organisationnelles insufflées par le siège, à les négocier, à les dévier et à se les approprier. Au final, nos observations montrent qu'une stratégie de survie pour la filiale revient non pas à combattre le changement mais à l'accompagner de manière à trouver ou à créer sa nouvelle place dans la chaîne de valeur globale. / This thesis proposes a grounded theory of the phenomenon of local survival within multinational corporations. The aim is to study the following question: what kind of strategies might be developed by manufacturing plants in order to survive and remain in the value chain of a multinational despite a context of globalization and costs rationalization? The historical analysis of the case of IBM Montpellier allows us to interpret the phenomenon of local survival as resulting from the maturation of a managerial process of survival by transformation. This process is composed of three stages: a compliance phase during which local actors feel little exogenous pressures and simply adopt and implement practices and directives coming from headquarter; an opposition phase that emerges in response to sudden threats and consists in contesting the diffusion of some logics in order to protect and maintain the established local order; and a transformation phase during which local actors seek to anticipate future evolutions of the company and redefine local practices and logics in order to influence or bypass certain decisions deemed to threaten the future of the site. The thesis highlights the paradoxical nature of this survival strategic process since it lies at the interface between resistance and compliance. The approach studied consists in translating, negotiating, or deviating organizational changes instilled by headquarter. Finally, our observations show that for subsidiaries, a survival strategy entails not to fight change but to support it in order to find or to create their new place in the global value chain.

Title: Evaluating the success of participants practical, summer and winter survival training. Objectives: The aim of this thesis was to evaluate and interpret the data. This data was collected over a period of several years, and observations were made by experts in the field of survival. Based on the course of the winter and summer survival, the idea was to observe if there are differences between successful men and women who best cope with stress. Observed people are generally students at Charles University. Methods: Data were collected during the course of survival thanks to observing instructors, who in no way influenced the behavior of the students in all activities associated with survival. Evaluating of behavior was conducted on the basis of six criteria established by survival instructors. The students completed the five-factor questionnaire NEOPS that was used to obtain personal profile of individual students. Results: For interpretation of the results was used Eyseneck's coordinate model of temperament. In this model they were recorded individual personality profiles obtained thanks to two fundamental dimensions - neuroticism and extroversion. Over 72% of students participating the survival seminar belong to a sanguine temperament, a person who is emotionally stable and openminded. Along...

<p>The work presented in this dissertation is focused on applying engineering methods to develop and explore probabilistic survival models for the prediction of decompression sickness in US NAVY divers. Mathematical modeling, computational model development, and numerical optimization techniques were employed to formulate and evaluate the predictive quality of models fitted to empirical data. In Chapters 1 and 2 we present general background information relevant to the development of probabilistic models applied to predicting the incidence of decompression sickness. The remainder of the dissertation introduces techniques developed in an effort to improve the predictive quality of probabilistic decompression models and to reduce the difficulty of model parameter optimization.</p><p>The first project explored seventeen variations of the hazard function using a well-perfused parallel compartment model. Models were parametrically optimized using the maximum likelihood technique. Model performance was evaluated using both classical statistical methods and model selection techniques based on information theory. Optimized model parameters were overall similar to those of previously published Results indicated that a novel hazard function definition that included both ambient pressure scaling and individually fitted compartment exponent scaling terms. </p><p>We developed ten pharmacokinetic compartmental models that included explicit delay mechanics to determine if predictive quality could be improved through the inclusion of material transfer lags. A fitted discrete delay parameter augmented the inflow to the compartment systems from the environment. Based on the observation that symptoms are often reported after risk accumulation begins for many of our models, we hypothesized that the inclusion of delays might improve correlation between the model predictions and observed data. Model selection techniques identified two models as having the best overall performance, but comparison to the best performing model without delay and model selection using our best identified no delay pharmacokinetic model both indicated that the delay mechanism was not statistically justified and did not substantially improve model predictions.</p><p>Our final investigation explored parameter bounding techniques to identify parameter regions for which statistical model failure will not occur. When a model predicts a no probability of a diver experiencing decompression sickness for an exposure that is known to produce symptoms, statistical model failure occurs. Using a metric related to the instantaneous risk, we successfully identify regions where model failure will not occur and identify the boundaries of the region using a root bounding technique. Several models are used to demonstrate the techniques, which may be employed to reduce the difficulty of model optimization for future investigations.</p> / Dissertation

Etude à l'aide des outils de transcriptomique de 17 cultures primaires, maintenues à l'état vivant par xénogreffes et cultures cellulaires, et issues de patients ayant présenté un adénocarcinome pancréatique. Par clustering hiérarchique basée sur l'ensemble des gènes du transcriptome tumoral, 5 patients avec dénomination anonyme se sont fortement distingués des autres patients et présentaient de façon similaire des tumeurs peu différenciées sur le plan histologique et une survie péjorative de moins de 8 mois. Dans cette population de « courts survivants », un total de 942 gènes exprimés de façon significativement différentielle a été retrouvé. Parmi ces gènes, 439 gènes sont apparus significativement sous exprimés et 505 gènes significativement surexprimés (fold change ≥2). L'analyse par GO a montré que parmi ces 942 gènes différentiellement exprimés, nous avons retrouvé un enrichissement important chez les courts survivants, des gènes impliqués dans le cycle cellulaire et l'activité mitotique, la réponse cellulaire au stress, le métabolisme cellulaire ainsi que le métabolisme de l'ADN et l'organisation chromosomique. Par ailleurs, nous avons choisi parmi les 17 cultures primaires, les 3 lignées cellulaires les plus sensibles et les 3 les plus résistantes aux drogues selon les résultats des tests de « Chimiogramme ». Plusieurs gènes ont été identifiés comme spécifiquement surexprimés ou sous-exprimés en relation avec une sensibilité ou une résistance particulières des cellules aux drogues utilisées. Nous avons identifié 671 gènes associés à la gemcitabine, 1107 à l'oxaliplatine, 308 au 5-FU et seulement 34 et 46 au docétaxel et au SN38 respectivement. / We developed an efficient strategy in which PDAC samples from 17 consecutive patients were collected by Endoscopic Ultrasound-Guided Fine-Needle Aspiration (EUS-FNA) or surgery and preserved, by an original approach, as breathing tumors by xenografting and as a primary culture of epithelial cells. Transcriptomic analysis was performed from breathing tumors by an Affymetrix approach. We observed a significant heterogeneity in the RNA expression profile of tumors. However, the bioinformatic analysis of this data was able to discriminate between patients with long- and short-term survival corresponding to patients carrying poorly-differentiated PDAC tumors respectively. We identified 942 genes with statically different expression. Among these genes, 439 were under-expressed and 505 genes over-expressed (fold change ≥2) in short survivors. Primary culture of cells allowed us to analyze their relative sensitivity to anticancer drugs in vitro by a "Chemogram", by similarity with the antibiogram for microorganisms, establishing an individual profile of drug sensitivity. As expected, the response was patient-dependent. Interestingly, we also found that the transcriptome analysis predict the sensitivity of cells to the five anticancer drugs the most frequently used to treating patients with PDAC. In conclusion, using this approach, we found that the transcriptomic analysis could predict the sensitivity to anticancer drugs and the clinical outcome of patients with PDAC.

Thesis advisor: Susan Michalczyk / This 2005-2006 Senior Honors Thesis is the story of Holocaust survivor Edgar Krasa and his experience in the Nazi concentration camps. As a human, I felt it was my duty to share his remarkable account with the world. As a writer, I have sought to leave him with something tangible, a small tribute to the suffering he endured. I have attempted to maintain a delicate balance between research and storytelling, as Mr. Krasa's story exists in the context of the theoretical framework I have studied. This work is not meant to speak only of gas chambers, death marches, bitter cold, and death. Rather, it stands as a testament to human loyalty, hope, determination, and unwavering belief in life. It is meant to expose the depths and resilience of the human soul. / Thesis (BA) — Boston College, 2006. / Submitted to: Boston College. College of Arts and Sciences. / Discipline: College Honors Program.

An important factor in the rise of health care costs is the structure and performance of health care markets. This is an area in which policy can be particularly effective. Health care markets are characterized by complex interactions between consumers, physicians, insurers, facilities, and government agencies. Physicians, insurers, and facilities operate under a mix of objectives and governance structures. The many varieties of objectives and governance structures can be broadly categorized as for-profit, not-for-profit, and governmental. In the three chapters that follow I construct a theoretical framework to analyze hospital behavior and use a 30 year panel of data on Californian hospitals to assess the validity of the models and to identify the impact of governance structure on behavior. Chapter II addresses firm objectives. I find that firms have a continuum of weighting allocations, with for-profit firms placing greater weight on profit, government firms placing greater weight on social objectives, and not-for-profit firms locating in a middle ground. All three types of governance structures display overlap in their objectives. In Chapter III, I identify patterns in hospital entry and exit. Like most manufacturing industries, entering hospitals are significantly smaller than incumbent hospitals and exiting hospitals are significantly smaller than surviving hospitals. The patterns of entry and exit for hospitals vary systematically with both governance structure and geographic diversification. In Chapter IV, I develop a model of hospital entry that explains heterogeneous entry size and firm survival. I find entry size to be a relatively important factor in firm survival. In general entering on a larger scale increases the probability of survival. Despite this fact many firms enter relatively small. The model that I develop resolves small entry as a rational choice for uncertain firms.

Procedimentos endodônticos regenerativos proporcionaram mudanças no tratamento de pacientes com dentes imaturos e periodontite apical possibilitando desenvolvimento radicular completo e menor incidência de fratura dental. Medicações intracanal são utilizadas para a realização da desinfecção; entretanto, o efeito delas sobre às células da papila apical é pouco elucidado. Adicionalmente, pouco se conhece a respeito do efeito destas substâncias sobre células previamente submetidas à condição pró- inflamatória. O objetivo deste estudo foi avaliar a citotoxicidade de medicações intracanal empregadas em procedimentos regenerativos em Endodontia sobre células de papila humana em cultura em condição fisiológica e ativada. Cultura de células foi estabelecida a partir da papila apical removida de um terceiro molar imaturo extraído. As substâncias estudadas foram a pasta tripla antibiótica modificada: ciprofloxacina, metronidazol e cefalosporina (1:1:1); CFC: ciprofloxacina, metronidazol e hidróxido de cálcio (1:1:2) e CFC modificado: ciprofloxacina, metronidazol e hidróxido de cálcio (2:2:1). Parte das células foram estimuladas previamente por ácido lipoteicóico (LTA) de Enterococcus faecalis por 7 dias. Após plaqueamento, células foram expostas a concentrações crescentes das medicações por 1, 3, 5 e 7 dias. Foram avaliados viabilidade celular por meio de brometo de 3-(4,5-dimetiliazol-2-il)-2,5-difeniltetrazólio (MTT) e liberação de óxido nítrico (NO) pelo método de Griess. A análise estatística foi realizada por meio de análise de variância a 1 critério (ANOVA) seguida de pós teste de Tukey, com nível de significância de 5%. O CFC modificado foi a medicação que demonstrou menor efeito citotóxico sobre a viabilidade celular nos tempos experimentais estudados, o CFC promoveu queda da viabilidade celular especialmente após 7 dias de contato. A pasta tripla antibiótica modificada resultou em comprometimento importante da viabilidade podendo ser considerada a mais citotóxica. A ativação celular por LTA resultou em níveis aumentados de atividade mitocondrial para todas as medicações sendo mais evidente nos períodos experimentais mais longos. A ativação celular também contribuiu para níveis maiores de óxido nítrico. Conclui-se que o efeito citotóxico das medicações testadas é dependente de sua concentração, tempo de contato e condição celular, sendo a pasta tripla antibiótica modificada a mais citotóxica em concentrações elevadas podendo implicar clinicamente na diminuição da viabilidade das células da papila apical podendo diminuir o sucesso dos procedimentos regenerativos. / Regenerative Endodontic procedures have provided changes in treatment of patients with immature teeth and apical periodontitis enabling full root development and lower incidence of dental fracture. Intracanal dressings are used for disinfection; however, their effect on apical papilla cells is poorly elucidated. Additionally, the effect of these substances on cells previously subjected to proinflammatory condition is still unknown. The aim of this study was to evaluate the cytotoxicity of intracanal dressings used in Endodontics regenerative procedures on cultured human apical papilla cells at physiologic and activated condition. Cell culture was established from the apical papilla removed from an extracted immature third molar. The substances studied were triple antibiotic modified paste: ciprofloxacin, metronidazole and cephalosporin (1:1:1); CFC: ciprofloxacin, metronidazole and calcium hydroxide (1:1:2) and modified CFC: ciprofloxacin , metronidazole and calcium hydroxide (2:2:1). Part of the cells was stimulated previously with lipotheichoic acid (LTA) of Enterococcus faecalis por 7 days. Once plated, cells were exposed to increasing concentration of the medications for 1, 3, 5 and 7 days. Cell viability was evaluated by means of 3-bromide (4.5-dimetiliazol-2-yl) -2.5-difeniltetraze (MTT) and Nitric Oxide (NO) release was assessed by the Griess method. The statistical analysis was done through analysis of variance with 1 criteria (ANOVA) followed by Tukey test with 5% of significance level. Modified CFC was the medication that demonstrated the less cytotoxic effect on cell viabilityat the experimental periods studied while CFC promoted significant decrease on cell viability specially after 7 days of contact. The modified triple antibiotic paste resulted in important alteration of cell viability being considered the most citotoxic. Cellular activation by LTA resulted in increased levels of mitochondrial activity for all medications being more evident at the longer experimental periods. Cellular activation also contributed to higher levels of nitric oxide release. In conclusion, the cytotoxic effect of the tested medications is dependent on concentration, time of contact and cellular condition, being the triple antibiotic modified paste the most cytotoxic in high concentrations leading clinically in the decreased of the cells viability of the apical papilla, decreasing the success of regenerative procedures.

Introdução: A estimativa de sobrevida de pacientes com HIV/aids aumentou após a terapia antirretroviral de alta potência: no entanto, a mortalidade por doenças hepáticas também cresceu. Objetivos: Estimar a probabilidade acumulada de sobrevida após o diagnóstico de aids entre pacientes coinfectados HIV/HCV e realizar análise exploratória para investigar fatores relacionados à sobrevida desses pacientes. Metodologia: Estudo de coorte não concorrente, utilizando sistemas de Informações: o de Agravos de Notificação, o de informação laboratorial e o de informação da vigilância epidemiológica do Centro de Referência e Treinamento DST/AIDS-SP, de pacientes com aids maiores de 13 anos, acompanhados no ambulatório geral. As variáveis estudadas foram: hepatite C, hepatite B, categoria de exposição, contagem de células T CD4+, faixa etária, escolaridade, cor, sexo e períodos de diagnóstico de aids: 1986 a 1993, 1994 a 1996, 1997 a 2002 e 2003 a 2010. Foi utilizado o estimador de Kaplan-Meier, o modelo de Cox e as estimativas das hazard ratio (HR) com os respectivos intervalos de confiança (IC 95 por cento ). Resultados: De um total de 2.864 pessoas incluídas, com idade mediana de 35 anos, 219 foram a óbito (7,5 por cento ). De 358 (12,5 por cento ) coinfectados, 159 (45,1 por cento ) eram usuários de drogas injetáveis (UDI) e de 2.506 não coinfectados, 96 (3,9 por cento ) eram UDI. A probabilidade acumulada de sobrevida entre coinfectados, a partir do diagnóstico de aids, foi 100 por cento aos 60 meses no período de 1986 a 1993; 27,8 por cento aos 168 meses no período de 1994 a 1996; 76,3 por cento aos 168 meses no período de 1997 a 2002 e 92,8 por cento aos 96 meses no período de 2003 a 2010. As curvas de sobrevida foram diferentes entre coinfectados e não coinfectados no período de 1994 a 1996 (log rank = 19,8; p < 0,001) e no período de 1997 a 2002 (log rank = 38,8; p < 0,001). No modelo de Cox multivariado, mostraram-se preditores de óbito, independentemente das outras variáveis: ter hepatite C (HR = 2,9; IC 2,1-3,9), ter hepatite B (HR = 2,5; IC 1,7-3,6), ter até 3 anos de estudo (HR = 2,3; IC 1,5-3,6), ter 50 anos ou mais de idade (HR = 2,1; IC 1,3-3,2). Ter diagnóstico de aids no período entre 1997 a 2002 mostrou-se fator de proteção ao óbito (HR = 0,4; IC 0,3-0,5). Conclusões: Coinfectados HIV/HCV apresentaram menor sobrevida quando comparado com não coinfectados nos períodos de diagnóstico de aids 1994 a 1996 e 1997 a 2002. A partir do período 1994 a 1996, observou-se aumento significativo na probabilidade acumulada de sobrevida entre coinfectados, sendo que no período 2003 a 2010, essa probabilidade foi semelhante entre coinfectados e não coinfectados, refletindo possível impacto do tratamento da hepatite C / Introduction: The estimated survival of patients with HIV/AIDS has increased after highly active antiretroviral therapy; mortality due to liver diseases, however, has also increased. Objectives: To estimate the accumulated probability of survival after AIDS diagnosis among HIV/HCV co-infected individuals and to perform an exploratory analysis to investigate factors related to the survival of these patients. Method: Non-concurrent cohort study, using data from the National Disease Reporting Information System, the laboratory and epidemiological surveillance information systems of the SP-STD Reference and Training Center-CRT, of patients over 13 years of age, followed at the general outpatient clinic. The following variables were studied: hepatitis C, hepatitis B, exposure category, T CD4+ cell count, age group, schooling, color, sex, and AIDS diagnostic periods: 1986 to 1993, 1994 to 1996, 1997 to 2002 and 2003 to 2010. Survival analysis was performed using the Kaplan-Meier estimator and the Cox model, with estimates of the hazard ratio (HR) and respective confidence intervals (95 per cent CI). Results: Of a total of 2,864 individuals included, with a median age of 35 years, 219 died (7.5 per cent ). Of the 358 (12.5 per cent ) HIV/HCV co-infected individuals, 159 (45.1 per cent ) were injecting drug users (IDU), and of the non-co-infected 2,506, 96 (3.9 per cent ) were IDU. The accumulated probability of survival among HIV/HCV co-infected individuals at 60, 168, 168 and 96 months as of AIDS diagnosis, was 100 per cent in the 1986 -1993 period; 27,8 per cent in the 1994-1996 period; 76,3 per cent in the 1997-2002 period; and 92,8 per cent in the 2003-2010 period. The survival curves were different between co-infected and non-co-infected individuals in the 1994-1996 (log rank = 19,8; p < 0,001) and in the 1997-2002 (log rank = 38,8; p < 0,001). In the multivariate model, regardless of other variables, the following were predictors of death: having hepatitis C (HR = 2.9; CI 2.1-3.9); having hepatitis B (HR = 2.5; CI 1.7-3.6); being 50 years old or over (HR = 2.1; CI 1.3-3.2) and having up to 3 years of schooling (HR = 2.3; CI 1.5-3.6). AIDS diagnosis between 1997 and 2010 was shown to be a protective factor for death (HR = 0.4; CI 0.3-0.5). Conclusions: HIV/HCV co-infected individuals had shorter survival, when compared to non-co-infected individuals in the 1994-1996 and in the 1997-2002 AIDS diagnostic periods. As of the 1994-1996 period, a significant increase in the accumulated probability of survival among HIV/HCV co-infected individuals was observed. In the 2003-2010 period, the probability was similar between co-infected and non-coinfected individuals, showing the possible impact of hepatitis treatment

A reposição de dentes perdidos por meio de próteses implanto-suportadas tornou-se uma opção de tratamento previsível e aceitável tanto para pacientes parcialmente como totalmente desdentados. Após sua instalação, os implantes de titânio interagem com fluidos biológicos e tecidos, sendo que a direta aposição óssea sobre a superfície do titânio é fundamental para o carregamento desses implantes. As características superficiais dos implantes podem influenciar na interação implanteosso, na taxa e qualidade da osseointegração. O objetivo desse estudo clínico retrospectivo foi avaliar a taxa de sobrevivência de implantes osseointegrados com superfície Acqua e verificar se existe interferência de determinadas variáveis na perda de implantes: região de instalação, tipo de reabilitação protética, tipo de carregamento, tempo de carregamento, experiência do cirurgião, enxertos ósseos, tipo de sítio para instalação, uso de tabaco e diabetes. Foram avaliados 131 pacientes, totalizando 331 implantes instalados com conexão interna tipo cone Morse e superfície Acqua. Os dados foram coletados de prontuários clínicos e tabulados e nenhum paciente foi excluído devido a qualquer doença sistêmica, gênero, raça, hábitos parafuncionais e tabagismo. A análise estatística incluiu estatísticas descritivas para todos os parâmetros clínicos avaliados e foi aplicado o método exato de Fisher. Foram avaliados implantes instalados anteriormente a março de 2014 e o tempo de acompanhamento do carregamento dos implantes foi de 0 a 55 meses. Entre as variáveis avaliadas apenas o tipo de reabilitação protética influenciou de forma significativa na falha de implantes. Sete implantes (2,11%) foram considerados perdidos, totalizando uma taxa de sobrevivência de 97,89%. Os implantes com superfície Acqua apresentaram alto índice de sobrevivência nas mais diversas situações e com a associação de diversos fatores de risco, provando ser uma superfície confiável e apropriada para a aplicação na prática clínica diária. / The replacement of lost teeth by dental implant has become a predictable and acceptable treatment option for patients either partially or fully edentulous. After place, titanium implants surface interact with biological fluids and tissues, and direct bone apposition on the titanium surface is critical for loading these implants. The surface characteristics of implants can influence the implant-bone interaction in the rate and quality of osseointegration. The aim of this retrospective clinical study was to evaluate the dental implants survival rate with Acqua surface and check for interference of certain variables in the loss of implants: placed region, type of prosthetic rehabilitation, loading type, load time, surgeon experience, bone grafts, installation site, tobacco use and diabetes. One hundred thirty one patients, totaling 331 implants inserted with internal Morse taper connection and Acqua surface. Data were collected from medical records and tabulated and no patient was excluded due to any systemic disease, gender, race, parafunctional habits and smoking. Statistical analysis included descriptive statistics for all clinical parameters evaluated and was applied Fishers exact test. Were evaluated implants placed prior to March 2014 and the follow-up time of loading of the implants was 0-55 months. Among the variables evaluated only the type of prosthetic rehabilitation influenced significantly in implant failure. Seven implants (2.11%) were considered lost, amounting to a survival rate of 97.89%. Implants with Acqua surface showed high survival rate in different situations and with the association of various risk factors, proving to be a reliable and suitable surface for application in clinical practice.

Os cânceres ou neoplasias malignas vêm assumindo um lugar cada vez mais importante entre as doenças que acometem a população feminina, representando no Brasil e no mundo, importante causa de morte. O câncer de mama é o segundo tipo de câncer mais freqüente no mundo e o primeiro entre as mulheres. Os avanços da medicina, possibilitando tratamentos mais eficientes e técnicas que viabilizam a detecção precoce, têm contribuído para o aumento da sobrevida das mulheres com câncer de mama.Tendo em vista a alta incidência do câncer de mama eo aumento da sobrevida, faz-se cada vez mais necessário compreender a realidade destas mulheres que experienciam o adoecimento e a sobrevivência a ele. Este trabalho teve como objetivo compreender a experiência de sobreviver ao câncer de mama a partir de elementos presentes nas histórias de mulheres sobreviventes. O estudo é de natureza qualitativa, realizado com 15 mulheres sobreviventes de câncer de mama, que haviam concluído o tratamento há no mínimo cinco anos. A técnica utilizada para coleta de dados foi a entrevista narrativa e a análise foi feita com base nos estudos de Little et al. (2002) e Frank (2012). Os dados foram organizados em torno de três momentos principais: o início da história - o diagnóstico; o enfrentamento - tratamento; e o desfecho - retomando a vida, buscando compreender o sentido que cada participante atribuía a sua história enquanto uma pessoa que passou pelo tratamento do câncer e sobreviveu. Foi percebido que muitas mulheres tiveram sua identidade mudada após a experiência do adoecimento e a maioria delas conseguiu retomar sua vida a uma condição semelhante à anterior à doença. Assim os resultados revelam a singularidade e diversidade no modo de experienciar o adoecimento e a sobrevivência e as repercussões desta experiência na identidade da mulher. / Cancers or malignant neoplasias have been reported as important diseases among women, representing causes of death not only in Brazil but in the whole world. Breast cancer is the second most frequent type of cancer worldwide and the first among women. Medical advancements have improved the survival rates for women with breast cancer through more efficient treatments and techniques. Considering the high incidence of breast cancer and the increase of survival rates, the understanding of these women\'s realities - being sick and recovering from it - has become extremely important. The objective of this study was to understand the experiences of surviving breast cancer from elements present in the stories of women survivors. The study is qualitative - 15 surviving breast cancer women were studied and their treatments had been finished 5 years earlier at least. The technique used to collect data was through interviews and the analysis was done based in the studies of Little et al. (2002) and Frank (2012). The data was organised considering 3 main moments: the beginning of the disease (medical diagnosis); the confrontation (treatment); and the end (regaining life). The main objective was to understand the meaning each woman gave to her experience after having survived. Many women have had their identities changed after the disease and most of them have managed to regain their lives. Thus, the results show the singularity and the diversity in experiencing getting sick and surviving and the effects of these experiences in women\'s identities.