Le métabolisme est la somme des réactions chimiques dans un organisme. L’énergie leur permet d’effectuer la biosynthèse, le maintien des fonctions vitales et l’activité physique. Si l’énergie est transformée en chaleur nous pouvons déterminer le taux de transformation d’énergie chimique en taux métabolique (TM) et nous pouvons donc calculer les besoins énergétiques d’un animal. Le principal objectif de ce travail est d’évaluer le métabolisme énergétique chez la punaise hématophage Rhodnius prolixus. Nos résultats montrent, que le TM de l’alimentation chez R. prolixus atteint jusqu’à 17 fois le TM au repos. Le quotient respiratoire est de 0,83 pendant le repos et 0,52 pendant l’alimentation. De plus, la désactivation des protéines permettant gérer le choc thermique, diminuent le TM pendant la digestion. Le coût énergétique (CE) de la marche peut atteindre jusqu’à 1,7 fois le CE pendant le repos. Finalement, le CE de la production d’un oeuf chez R. prolixus est approximativement de 11,7 J. L’ensemble de nos résultats apportent des outils qui fournissent des éléments nécessaires pour mieux contrôler la transmission de maladies vectorielles. / Metabolism is the sum of all the chemical reactions in an organism. Energy uptake allows animals to perform biosynthesis, maintenance, and external work. If the energy produced is converted into heat, we can estimate the energy metabolism as the rate of conversion of chemical energy into metabolic rate (MR), which allows the calculation of energy requirements. The main objective of this work is to assess the metabolic cost of physiological work in the blood-sucking bug Rhodnius prolixus. Our results show that feeding is costly. The MR during feeding in R. prolixus reaches up to 17 times the MR during rest. The mean respiratory quotient is 0.83 during rest and 0.52 during feeding. We showed that the deactivation of Heat Shock Proteins on R. prolixus, causes a diminution of MR during digestion. Then, we showed that the energy cost (EC) during walking can reach up to 1.7 times the EC during rest. Finally, we found that the EC of production of one egg of R. prolixus was 11.7 J. All our results provide tools to a better understanding of biology and ecology of an hematophagous insect to provide the necessary elements to better control of transmission of vector-borne diseases.

The dialectics of globalization and multiculturalism is encountered everywhere and is an inescapable world reality. It has also become a major factor affecting teacher education. As a meeting ground and intercept for educational programs, teacher education provides an interface for both global imperatives and local identities. Ethiopia has pronounced achievements in most education programs at all levels, although official documents indicate variance in the quality of attainment across the levels (ESDP IV, 2011). Local studies (Ambisa, 2008; Amaliraj, 2008) also found that teacher education suffers from a lack of relevance and poor quality. Moreover, the demand for qualified teachers who are competent to shape the young generation through balancing the glocal context is increasing. This study investigated how local identities and global imperatives are integrated in contemporary Ethiopian teacher education at all levels. Critical theory was employed as the paradigm for the study. This epistemological view underpinned a discussion of the effect of globalization and multiculturalism on the world’s functioning. The research approach in the empirical study was qualitative and an interpretive case study method was employed. The units of analysis were literatures, such as The Lexus vs. the Olive Tree; McWorld vs. Jihad; The Clash of Civilization: The West vs. the Rest; and Demonstrating Common World Culture of Education (CWCE) or Locating A Globally Structured Agenda for Education (GSAE); and the contemporary Ethiopian teacher education programs (the PGDT and TESO programs). Data collection tools were basic dialectical questions under Eemeren’s (1986) established ‘system of norms’, observation, interviews and focus group discussions. Confidentiality, anonymity, informed consent, resolution of conflict of interest and intellectual ownership were considered in the study. The dialectical analysis investigated the four quadrant glocal relationships model and described the role players in each quadrant where nations may locate themselves. Moreover, the comparative analysis indicated that globalization has not yet become an issue in contemporary Ethiopian teacher education, while multicultural practices are fragmented and are addressed only in response to ethnic demands for accommodation. To this end, Ethiopian teacher education should redefine its programs in order to adjust to global understanding in an endeavor to produce competent teachers for the global market. / Curriculum and Instructional Studies / D. Ed. (Curriculum Studies)

A energia elétrica de uso doméstico no cenário mundial é um fenômeno recente que incorporou modulações temporais na expressão dos ritmos biológicos, como os hábitos alimentares e de sono. Após sua popularização, tecnologias eletrônicas foram criadas e incorporadas às nossas rotinas diárias. O acesso à iluminação elétrica promove uma maior flexibilidade na organização temporal das nossas atividades por facilitar o controle de extensão da fase de atividade para horas mais tardias da noite. Assim, essa situação pode constituir um desafio temporal ao organismo, gerado pelas oscilações das pistas temporais, adiantando ou atrasando a ocorrência de eventos rítmicos como a alimentação/jejum, atividade/repouso e metabolismo. O estudo foi realizado com 27 universitários entre 18 a 30 anos (17 mulheres; 10 homens) nos quais o comportamento alimentar e de sono foi registrado por meio do uso de diários e os ciclos de atividade/repouso e claro/escuro por meio de actímetros. Observada uma associação indireta entre o uso de equipamentos eletrônicos e o aumento no consumo alimentar. A associação observada em relação ao uso dos equipamentos com a ingesta está mais amparada no atraso do início do sono que propicia o aumento observado da ingesta média na fase noturna. No longo prazo o atraso da fase do sono e a diminuição da sua duração pode gerar um desalinhamento na regulação da expressão dos padrões temporais de atividade/repouso e alimentação/jejum que pode alterar o padrão do comportamento alimentar / Electric energy used widely in domestic context is a recent phenomenon that incorporates temporal modulations on the expression of biological rhythms and behaviour, like food ingestion and sleep patterns. After popularization of electric energy, electronic technologies have been created and incorporated to our routines. Access to electric light can promote more flexibility on temporal organization of our activities which allow for an extension of the wake phase to later portions of the night. Thus, that situation could promote temporal challenges to the organisms, generated by oscillations of temporal signals, which may cause phase advances or delays in rhythmic events like feeding/fasting, rest/activity and metabolic functions. This study involved 27 university students between 18 to 30 years old (17 women; 10 men) where feeding and sleep behavior data were collected with feeding and sleep diaries; the rest/activity rhythm and the light/dark cycle data were collected with actimeters. The association observed in relation to the use of the electronic equipments with the food intake is supported by the delay of the beginning of rest that propitiates the increase of the average intake in the nocturnal phase. In the long term, the delay of the rest phase and the decrease of its duration can generate a misalignment in the regulation of the expression of the temporal patterns of rest/activity and feeding/fasting and thus change the temporal pattern of the feeding behavior

L'imagerie par résonance magnétique (IRM) est un outil remarquable pour le diagnostic clinique, aussi bien pour l'imagerie cérébrale que pour l'imagerie cardiaque et abdominale. En IRM cardiaque, deux problèmes sont récurrents : la non reproductibilité des cycles cardiaques et le mouvement respiratoire. L'IRM cardiaque morphologique est généralement faite avec une séquence composée d'une préparation longue, visant à annuler le signal du sang pour accentuer le contraste au niveau du myocarde, et de l?acquisition à proprement parler. Ces acquisitions sont généralement faites en mésodiastole (phase de relaxation passive du coeur) ce qui permet de satisfaire les contraintes liées à l'annulation du sang et d'éviter les problèmes liés aux non reproductibilités des cycles cardiaques car la mésodiastole est longue. Il est donc difficile de satisfaire les contraintes liées à l?annulation du sang pour faire les acquisitions en télésystole (phase où le coeur est contracté) à cause des non reproductibilités cardiaques car la télésystole est courte. Afin de passer outre ces limitations et de pouvoir acquérir ces mêmes images morphologiques en télésystole, nous proposons une nouvelle méthode adaptative qui permet à la fois de placer la fenêtre d'acquisition de manière optimale et de satisfaire les contraintes liées à l'annulation du sang. Une application de cette méthode a également été mise en place pour estimer et comparer les temps de relaxation transversale (T2) entre télésystole et mésodiastole. Pour la gestion prospective du mouvement respiratoire, le point crucial est d'estimer les mouvements en temps réel en perturbant au minimum les signaux de résonance magnétique. Pour ce faire nous proposons une méthode basée sur l'estimation paramétrique des mouvements en temps réel à partir des signaux physiologiques disponibles (ceintures respiratoires et ECG). Cette méthode a été testée et les résultats montrent son intérêt et sa fiabilité par rapport aux erreurs faites au niveau du mouvement. Une méthode de reconstruction incluant les mouvements a également été utilisée pendant ces travaux afin de faire de l'imagerie en télésystole en respiration libre et d'utiliser d'autres types de capteurs respiratoires comme certains signaux de résonance magnétique. Ainsi pendant ces travaux, des méthodes adaptatives ont été mises en place afin de mieux gérer le mouvement et de prendre en compte les spécificités de chaque patient. Ces travaux ouvrent la voie de l'imagerie par résonance magnétique adaptative pleinement fonctionnelle dans un contexte clinique / Magnetic resonance imaging (MRI) is a valuable tool for the clinical diagnosis for brain imaging as well as cardiac and abdominal imaging. In cardiac MRI, there are two challenging issues: the non reproducibility of cardiac cycles and respiratory motion. Morphological cardiac MRI is generally performed with a pulse sequence composed of a long preparation, to cancel the blood signal and thus enhance the contrast of the myocardium, and the acquisition itself. These acquisitions are performed during the mid-diastolic rest (relaxation period of the heart) to satisfy constraints to cancel the blood signal and to avoid problems linked to the cardiac non reproducibility because the mid-diastolic rest is long. Consequently, to acquire images in end-systolic rest (when the heart is fully contracted) while taking into account constraints to cancel the blood signal is not straight forward due to cardiac non reproducibility because the end-systolic rest is short. To overcome these limitations and to acquire images in end-systolic rest, a new adaptive method is introduced that allows to optimally placing acquisition windows while taking constraint for the cancellation of the blood signal into account. This method was applied to measure and compare transverse relaxation time (T2) between end-systolic and mid-diastolic rests. For prospective respiratory motion correction, the crucial point is to estimate motion in real-time without perturbing MR signal used for imaging. In order to solve this issue, a new method is introduced aiming at estimating motion parameters in real-time based on physiological signals such as respiratory bellows and ECG. This method is evaluated and results show its interest and its reliability regarding motion estimation errors. A reconstructions algorithm is also used in order to perform cardiac imaging during the end-systolic rest in free breathing and to use different kind of respiratory motion sensors such as MR signals. Hence, during this research work, several adaptive method were developed to get a better management of motion and to take into account specificity of each patient. These works open the way of fully functional adaptive magnetic resonance imaging in a clinical situation

The main purpose of the project was to investigate existing markets within the food- and cosmetic industry in order to determine a strategy for market entrance with the bonus product of Fresenius Kabi. The original bonus product, P080, is a rest product from the process where phospholipids are extracted from egg yolk powder. P80 is a refine version of the P080 where egg yolk oil has been extracted, hence the protein content in P80 is higher. The extracted egg yolk oil is the final portion of the bonus product. Thereby, the original bonus product can be divided into two refined fractions. This project investigates the potential for each of these three substances to be a part of a fictive product.  By scanning the global protein market as well as the egg yolk protein and egg oil market, seven potential product segments were discovered. These segments were further evaluated in order to bring out specific products that were potential candidates as products based on the bonus product.  The analysis resulted in two fictive products based on P080; high value nutrition bars and snacks for seniors, one based on P80; protein powder, and one based on egg yolk oil; dietary supplement. All presented in three business cases.

Toute cette recherche se concentre sur le portrait en peinture comme possibilité de la rencontre, de moments d’amitié. Il s’agit d’en analyser les enjeux en utilisant la philosophie et la psychanalyse comme outils théoriques. Comprendre combien cette pratique de corps-à-corps, de présence à présence s’inscrit dans le temps, le déploie, le relate. La rencontre, tout comme ma pratique, a pour origine le désir de l’Autre. Chacune de mes peintures est une réponse à cette demande : «Comment désires-tu être peint ?». Mes pinceaux, guidés par les paroles livrées dans mon atelier, tentent de s’approcher au plus près de ce qui est dit : quête impossible !... tant le langage implique une perte, nous divise. Nous nous percevons comme uniques car nous sommes séparés de l’autre, nous sommes entourés de vide. L’autre et le vide ne sont pas seulement extériorités, ils sont en nous, et pour la psychanalyse c’est par l’imaginaire que nous trouvons notre unité. La psychanalyse, la méditation, l’alchimie et la peinture ont ceci de commun qu’elles sont toutes des disciplines construites à partir de la pratique et chacune d’entre elles aborde l’introspection à sa manière, qui peuvent s’enrichir les unes les autres. / The present research work focuses on the painted portrait and the opportunity it offers to meet people and exchange moments of friendship. It aims at analyzing what is at stakes in this process by means of theoretical tools such as psychology and psychoanalysis. It is also concerned with the understanding of how this «hand to hand» and «presence to presence» practice gets its anchorage in time and how it unfolds it and refers to it. The get together process, as well as my own practice, are the expression of desire – desire of the Other. Each of my paintings is an attempt to answer this single question: «How would the person posing for me like to be painted?». Then, as if guided by his or her wish, my brushes enter into action in order to fulfill it to the best of my abilities – the task is of course impossible, because language implies a loss and gets us apart from one another. Each of us sees oneself as unique, for we are separated from each other: we are indeed surrounded by emptiness. The Other and emptiness don’t belong to the outside, they are part of ourselves. In the field of psychoanalysis, we manage to find our unity through imagination. Psychoanalysis, meditation, alchemy and painting have all in common to be based on practice. Each of these disciplines deals with insight in its own way: in the end they all benefit from each other.

Game theory and mechanism design have emerged as an important tool to model, analyze,and solve decentralized design problems involving multiple agents that interact strategically in a rational and intelligent way. Some examples of these design problems include: auctions and markets in electronic commerce; network economics; dynamic pricing; routing protocols in wireless networks; resource allocation in computational grids; algorithms for selfish agents;etc. The motivation for this doctoral work springs from the high level of current interest indesigning innovative mechanisms for solving emerging game theoretic problems in the area of electronic commerce. In this thesis, we focus on three such problems and advance the current art in mechanism design while developing new, innovative mechanisms to solve the problems. The first problem we explore is the highly strategic problem of forming a high value E-business supply chain by choosing the best mix of supply chain partners. In our research, we formulate the supply chain formation problem as a mechanism design problem in a generic wayand show that the well known VCG (Vickrey-Clarke-Groves) mechanisms provide an apt frame-work for solving this problem. We provide a compelling example of a three stage automotive distribution network to illustrate the power and e±cacy of the proposed methodology. The second problem we model and solve is that of designing a revenue maximizing sponsored search auction. This is a problem that is faced by every Internet search engine, such as Google,MSN, and Yahoo!, whenever it receives a search query. In our research, we take a comprehensivelook at existing auction mechanisms for this problem. Our work leads to an innovative new auction mechanism, which we call OPT (optimal mechanism), that exhibits a superior level ofperformance. The proposed mechanism extends, in a non-trivial way, the well known Myersonoptimal auction to the specific setting of sponsored search auctions. The proposed mechanism maximizes the revenue to the search engine and also satisfies two crucial properties, Bayesian incentive compatibility and interim individual rationality. The third contribution is in respect of Stackelberg problems, which are game theoretic problems that involve hierarchical and sequential decision making. By focusing attention on an important subclass of these problems, namely the Single-Leader-Rest-Followers (SLRF) problems, we extend all relevant aspects of classical mechanism design theory to the case of SLRF problems. We derive many important results in respect of procurement auctions with reserve prices using the developed theory. The research carried out as part of this doctoral work, we believe, advances the current art in mechanism design while developing innovative mechanisms to solve those problems.

Thesis (Ph.D.); Submitted to the Univ. of California, Berkeley, CA (US); 24 Nov 2004. / Published through the Information Bridge: DOE Scientific and Technical Information. "UCRL-TH-208645" Allen, M. 11/24/2004. Report is also available in paper and microfiche from NTIS.

The aim of this thesis is to describe information about GERD, its etiology, anatomy, pathology, treatment options and rehabilitation in patients with GERD. Lower oesophageal sphincter and antireflux barrier. The study was approved by the ethics committee. 30 probands were included in the study and their health status was verified using the Health Related Quality of Life questionnaire. A manometric catheter was inserted, proband was instructed to maintain various postural positions. Lying supine with lower limbs elevated above the surface, lying supine with lower limbs elevated above the surface with head fixated manualy, sitting and standing position, load in the center of gravity 3/6/9 kg, load outside the center of gravity 3/6/9 kg, lifting of the office chair. It has been shown that LES pressure increases in all postural positions compared to resting pressure. The positions activate the diaphragm to demonstrate the postural function of the diaphragm. The most significant change in LES pressures was in the postural position of lying supine with lower limbs elevated above the surface, the LES resting pressure of 20.34mmHg changed to the pressure of LES 40.92mmHg. Clinical experience and studies have shown that patients with GERD have disposition for respiratory and / or vertebrogenic difficulties....

The chapter titled Present state focuses on the problem of gerontology and geriatrics. Other chapters include description of the most outstanding neuropsychical and somatic changes in the old-age. Next chapters deal with functional examine and geriatric rehabilitation problem.The objective of the thesis was assessing the extent of self-reliance and psychical changes affecting all the occupants of using Crichton Geriatric Rating Scale.146 seniors were tested according to the Crichton Geriatric Rating Scale.Three hypotheses were stated. It was expected that the results of the Crichton tests would correlate with the results of MiniMental Test. Another hypothesis was that there would be better results of the test done to the people whose family care for them actively. The last hypothesis expected worse results of the people who have been in the retirement home for more than three years.The research has confirmed that the results of the Chrichton test and MiniMental test correlate. Correlation of the Crichton test with the active care and interest of the family for the senior and the length of their stay was not proved.