Global ETD Search

191	Xeroderma Pigmentosum Type A Deficiency Results in Increased Generation of Microvesicle Particles in Response to Ultraviolet B Radiation and Solar Simulated Light via Platelet-activating Factor Receptor Signaling Pathway Manjrekar, Pranali Sushil 16 May 2023 (has links) No description available. Pharmacology Toxicology Xeroderma Pigmentosum Ultraviolet B Radiation UVB microvesicle particles Solar Simulated Light Platelet-activating Factor acid sphingomyelinase XPA deficiency photosensitivity
192	Computationally Efficient Method in Predicting Axonal Excitation Izad, Olivier 27 March 2009 (has links) No description available. Anatomy and Physiology Bioinformatics Biomedical Research Mathematics activating function Deep Brain Stimuatlion, DBS Functional Electrical Stimulation, FES NEURON real time axon behavior algorithm recruitment order linear algorithm axon behavior
193	A New Role for Vitamin D Binding Protein in Bipolar Disorder Petrov, Brawnie Rebecca 03 August 2017 (has links) No description available. Nutrition vitamin D binding protein bipolar disorder major depressive disorder inflammation DBP-MAF macrophage activating factor inflammation western blot glycosylation actin immunoprecipitation bait
194	An investigation of Atf3, an adaptive-response gene, in breast cancer chemotherapy and stress response. Jalgaonkar, Swati 01 September 2016 (has links) No description available. Molecular Biology Cellular Biology Developmental Biology Oncology Activating Transcription Factor 3 Host tumor microenvironment breast cancer metastases paclitaxel chemotherapy stress gene in vivo cell fate tracing
195	The Roles Of ATF3, An Adaptive-response Gene, In Pancreatic Islet beta-cell Stress Response And Function Zmuda, Erik Jason 01 October 2009 (has links) No description available. Biology Cellular Biology Molecular Biology ATF3 Activating Transcription Factor 3 Islet Islet Transplantation Stress Response Diabetes High Fat Diet Insulin Apoptosis Inflammation
196	L'étude du "cross-talk" des voies de synthèse des prostaglandines E₂ et des leucotriènes B₄ dans le fonctionnement altéré des ostéoblastes sous-chondraux humains arthrosiques Maxis, Kelitha January 2004 (has links) Mémoire numérisé par la Direction des bibliothèques de l'Université de Montréal. Arthrose Os sous-chondral Ostéoblaste 5-lipoxygenase (5-LO) 5-lipoxygenase-activating protein (FLAP) PGE₂ LTB₄ TGF-[bêta]1 IL-18
197	Odborný anglický jazyk pro lékařské účely: Aktivizační metody a jejich vliv na osvojování slovní zásoby / English for Medical Purposes: Activating Teaching Methods and their Influence on Vocabulary Acquisition Vrběcká, Dagmar January 2019 (has links) The thesis deals with activating teaching methods and their influence on vocabulary acquisition in the field of English for Medical Purposes. The experimental research explores the extent to which activating teaching methods influence the acquisition of professional vocabulary. For this purpose, a set of activities (didactic games and role-plays) was created and implemented at the beginning of each teaching block for the subject Medical English I and II. The main objective of these activities was the review of word stock from the previous lessons. The review was focused on the form, meaning, and use of words. In the research, both quantitative and qualitative methods of data collection were used, including progress tests, credit tests, and questionnaires. Progress tests and credit tests were used to measure whether there was a significant statistical difference regarding the professional vocabulary acquisition between the experimental and control groups. A statistically significant difference was found between the experimental and control groups at the B2 level only. The questionnaires showed that activating teaching methods were positively evaluated by the B1 and B2 participants and were appreciated for their practical benefits (professional vocabulary acquisition, the positive influence on...
198	Therapeutic Antibody Against Neisseria gonorrhoeae Lipooligosaccharide, a Phase-variable Virulence Factor Chakraborti, Srinjoy 25 May 2017 (has links) Neisseria gonorrhoeae (Ng) which causes gonorrhea has become multidrug-resistant, necessitating the development of novel therapeutics and vaccines. mAb 2C7 which targets an epitope within an important virulence factor, the lipooligosaccharide (LOS), is a candidate therapeutic mAb. Ninety-four percent of clinical isolates express the 2C7-epitope which is also a vaccine target. Ng expresses multiple LOS(s) due to phase-variation (pv) of LOS glycosyltransferase (lgt) genes. mAb 2C7 reactivity requires a lactose extension from the LOS core Heptose (Hep) II (i.e. lgtG ‘ON’ [G+]). Pv results in HepI with: two (2-), three (3-), four (4-), or five (5-) hexoses (Hex). How HepI glycans impact Ng infectivity and mAb 2C7 function are unknown and form the bases of this dissertation. Using isogenic mutants, I demonstrate that HepI LOS glycans modulate mAb 2C7 binding. mAb 2C7 causes complement (C’)-dependent bacteriolysis of three (2-Hex/G+, 4-Hex/G+, and 5-Hex/G+) of the HepI mutants in vitro. The 3-Hex/G+ mutant (resistant to C’-dependent bacteriolysis) is killed by neutrophils in the presence of mAb and C’. In mice, 2- and 3-Hex/G+ infections are significantly shorter than 4- and 5-Hex/G+ infections. A chimeric mAb 2C7 that hyperactivates C’, attenuates only 4- and 5-Hex/G+ infections. This study enhances understanding of the role of HepI LOS pv in gonococcal infections and shows that longer HepI glycans are necessary for prolonged infections in vivo. This is the first study that predicts in vitro efficacy of mAb 2C7 against all four targetable HepI glycans thereby strengthening the rationale for development of 2C7-epitope based vaccines and therapeutics. monoclonal antibody therapy mAb mAb 2C7 chimeric antibody therapeutic antibody complement complement activation classical complement pathway phagocytosis neutrophil opsonophagocytosis vaccine engineered antibody antibody engineering C1q C3 gonorrhea Neisseria gonorrhoeae vaccines for gonorrhea treatments for gonorrhea hexamerizing antibody hexamerizing IgG antibody hexamers IgG hexamers complement activating antibody complement activating IgG Amino Acids, Peptides, and Proteins Bacteriology Immunology of Infectious Disease Immunoprophylaxis and Therapy Pathogenic Microbiology
199	Streshantering by studente aan 'n teologiese kollege deur middel van Rasioneel Emotiewe Terapie Booyens, Lorraine 11 1900 (has links) Text in Afrikaans / Students who study part time find themselves in a situation, with much pressure, which causes stress. The reason for this study was therefore to investigate the effectiveness of Rational Emotive Therapy as a coping technique for students in order to handle stress. A qualitative analysis was conducted and data was gathered primarily through group therapy and interviewing. The results of the research led to the conclusion that Rational Emotive Therapy could be effectively applied by students as a stresscoping mechanism / Educational Studies / M.Ed. Rational beliefs Stress Stresscoping Irrational beliefs Activating event Emotional consequences Behavioural consequences Disputing of irrational beliefs Fundamental goals Coping technique 616.8914 Rational-emotive psychotherapy Behavior therapy Stress management Counseling -- Religious aspects Psychology and religion Life skills
200	Využití problémového vyučování při výuce účetnictví na středních školách / The Use of Problem-based Teaching in Accounting Education in Secondary Schools Fišerová, Marie January 2008 (has links) This dissertation deals with the possibilities of using the teaching methods offered by the concept of teaching through problem solving in accounting education in business academies and economic lyceums. The main aim of this type of teaching should be above all the introduction of accounting as an important part of the students' economic thinking. The use of problem-based teaching is especially useful when explaining topics fundamental for the understanding of the basic principles of accounting. Accrual Basis Accounting being one of these topics, the thesis presents didactic material suited for problem-based teaching of this subject matter. It falls into the area of didactics of accounting, i.e. a scientific discipline deriving from the didactics of economic subjects.

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