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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Kvetching with Comics: How 20th Century American Comics Reflect the Ashkenazi Ethos of Pride and Shame

Kellerman, Aliza C 01 January 2013 (has links)
One of the most fundamental ways of understanding the struggles and delights of an ethnic group is to study the art the group produces. Art –visual, literary, auditory– functions as an expression of the history of the group. Often, what is considered great art in one culture is disparaged in many others. In my thesis, I will be examining how comics function as an expression of simultaneous pride and shame among Ashkenazi Jews, particularly comics created in the 20th century. Perhaps comics do not seem like an obvious expression of Eastern European Judaism. After all, there are far more renowned, and even sophisticated works to look at, such as the whimsical art of Marc Chagall and stately rabbinical paintings of Isidor Kauffman, or even the heady philosophical work of Theodor W. Adorno. “Ashkenazi expression” and “comics” do not seem intuitively connected. This disconnect is precisely why I want to explore the relationship between comics and Ashkenazi Jewry. In addition to many of the most prominent comic creators being Jewish, I posit that there is something inherently yiddish, Jewish, about American comics. The purpose of this essay is not to name individual comic artists in an attempt to prove the Jewishness of the the comic-book industry. Rather, I will explore why Jews of Eastern European descent gravitated toward the comic-book industry in the early to mid 20th century. I posit that American comics acted as an expression of a pride-shame tension found in American Jews of Eastern European descent. To explore this connection, I will first examine the origins of simultaneous Jewish pride and shame by tracing the roots of Eastern European Jewish self-hatred. Next, I will delve into why comics encapsulate this balance of self-deprecation and self-glorification. I will analyze both the nature of the medium itself, and the circumstances grounding the formation of American comics. Ashkenazi Jews, or Jews of Eastern European, specifically German descent, have been at the center of much scholarly literature. Although an extremely small percentage of the world's population, the bulk of Jews are Ashkenazi, as opposed to Sefardic. Much literature has been devoted to Ashkenazi Judaism, as the ethnic division has produced an impressive body of scientific and literary accomplishment. Although the countries from which Ashkenazi Jews originate are diverse, the key words surrounding Ashkenazi discourse are reoccurring. Concepts such as “exile,” “self-hatred,” and “Jewish humor” all arise. Another central concept is Yiddishkeit. Yiddishkeit literally translates to “Jewishness” in none other but the language of Yiddish. Yiddish has been the subject of both outward Ashkenazi expression –there is a great deal of Yiddish literature and art– and scholarly examination. Perhaps most recently, Michael Wex published a book called Born to Kvetch, an in-detail study of the history of Yiddish, and how it embodies Ashkenazi culture. Within this book, a particular theme appears: the theme of simultaneously occuring pride and shame. Jews created Yiddish as a result of the primary culture's rejection. However, after this initial dismissal, great pride emerged out of Yiddish, manifesting itself in rich Yiddish culture. Other scholars have explored the concept of Jewish self-hatred, and the fine line this self-hatred straddles between bona fide self-hatred and isolationist pride. Sander Gilman, who writes extensively about the topic, discusses how language and literature embody this dichotomous tension of pride and shame. While conducting research for the connection between comics and class in 20th century American, I came to the understanding that many of the founders of and participants in the American comic industry were Jewish. I dug up analyses of specific comics/graphic novels (usually Maus) exploring certain Jewish themes in comics, yet I had a hard time finding extensive research asking the question as to why comics and Jews have such a strong connection. In my thesis, I hope to further this question by not only investigating the circumstances surrounding comics that made Jews turn to the industry, but why comics themselves embody Jewish pride and shame. On a much humbler scale, I hope to accomplish what Wex has in Born to Kvetch, a linguistic analysis that provides insight into the greater ethnic group engaging with it. In chapter one, I will establish the pride-shame dichotomy found in Ashkenazi Judaism. I will first explore several biblical passages, including Lamentations, Micah, and Isaiah. By exploring these instances in the tanach, I will try to establish the uniqueness the Jews feel due to their personal and punitive relationship with God. Throughout these passages, we will see the Jews taking pride in the punishment God doles out for them, because such pain is indicative of the Jews' superiority among other nations. Next, I will provide a brief explanation of why I am choosing to focus on the act of conversion in the Medieval time period as an indicator of Jewish pride and shame. In specific, I will focus on infamous Johannes Pfefferkorn, who converted from Judaism to Christianity. Pfefferkorn is the perfect example of a Jew who both detested his Judaism, yet used it to his advantage to speak authoritatively about Judaism to Christians, as his professed textual knowledge gave him clout. Next, I will give an introduction on the connection between Otherness and language, explaining how Hebrew and the Talmud spurred both fascination and disgust toward Jews from their surrounding neighbors. After segueing into the origins of Yiddish as a language created out of exile, I will explain how though Yiddish originated out of spurning, the language became a source of pride of its rejected roots. I will consider the statements of various Yiddish authors, in particular American immigrant Isaac Bashevis Singer. Through both an analysis of Singer's self-reflection of his own life and an analysis of his short story, Gimpel the Fool, I will establish the pride Ashkenazi Judaism takes in its outsider status. Singer himself remarks of the positivity of being lonely and different. His character, Gimpel, is a foolish outcast. Much like the Jews in the biblical passages explored earlier in the chapter, he suffers constant misfortune and mockery, yet his very pain is what lends him favor in God's eyes. In chapter two, I will explore how 20th century American comics reflect the Ashkenazi dichotomy of pride and shame. Much like Yiddish is not a mainstream language, the idea of comics as mainstream art or literature has been greatly contested. I will try to determine which circumstances surrounding 20th century comics, and the comics themselves, connect with this pride-shame tension. I will use Paul Buhle's Jews and American Comics as a frame of reference, since the book often links comics and Yiddish. I will first give a brief history of the American comic-book, starting with the Hogan's Alley comics strip, and exploring up until the mid 20th century. By understanding the working-class origins of comics, we can better understand the low-brow perception of them from the standpoint of both their readers and their critics. I will then explain how American comics in the 20th century contained Jewish themes of pride and shame, despite their characters not being explicitly Jewish. I will more closely explore this idea through an analysis of the character Superman, drawing on both the commentary from the character's creators and the content clues of the character himself. A true foreigner, Superman masks his real identity, his superhuman powers. While his alias is what makes him exceptional, it is also the thing he abhors the most. Will Eisner, a giant in the world of comics, denies inserting Jewish identity in his own characters. However, his assistant, Jules Feiffer, half-jokingly claimed that his character, Denny Colt, featured in Eisner's The Spirit series, is in actuality a secret Jew. Instead of focusing on Colt and The Spirit, I will do a close reading of one of Eisner's other works, A Contract with God, which is an exemplary work of Jewish pride and shame. Contract contains a motif that is similar to that of the biblical passages analyzed in chapter one. The protagonist, Russian-American immigrant Frimme Hershe, has a personal relationship with God that leaves him demoralized and punished. I will then explore the use of visual stereotype in Contract, comparing it to that of Art Spiegelman's Maus, and contrasting it with that of the film Inglorious Basterds. I will argue that through engaging with Jewish visual stereotypes, the first two reveal them as falsehoods. Thus, through an admittance of these shamed images, the comics mock them. The latter film chooses to ignore stereotypes, thus leaving them extant. I will conclude the chapter by positing that Jews have coped with their constant exile through through the self-deprecation of comics. Buhle mentions that comics about Jewish-American gangsters turned into a source of pride, presumably for Ashkenazi American Jews. The trope, hated by others, was lauded by those it was forced upon. Much like Yiddish, comics may have been born out of exclusion, but they came to be a source of pride among Ashkenazi Jews.
2

Genetics of the immune cell receptors TCRB and CCR5 in human disease

Buhler, Marc McWilliams January 2003 (has links)
Abstract Early in the evolution of the vertebrates it is thought that two genomic duplications occurred, providing a basis for the evolution in body plan and neural crest of very early vertebrates and substantive material for further evolution of various gene families such as those making up a number of components of the adaptive vertebrate immune system. While the bony fish possibly had another, genome duplications are not generally a feature of vertebrate evolution and indeed the appearance of an antigen-adaptive immune recognition system may have served to limit the size that various vertebrate genomes, including that of the human, can in fact achieve. This initial step in vertebrate immune evolution, the establishment of recognition of non-self against the unique set of 'self' epitopes for an individual, provided an immensely powerful weapon in immune function with the ability to tailor a defense against as-yet-unseen dangers at any time albeit with the pitfall of autoimmune disease. As the recognition sites of the antigen receptor molecules such as TcR are produced by clonal modification of the segments provided in the germline and are thus not in the genome itself, pathogens have not been able to hijack this one component of the immune system in the way so many other components have been put to use throughout evolution, nor do these components necessarily reveal themselves as associated with disease through genome screens. Importantly, overall immune function is determined not just by the potential repertoire of recognition receptors but also by the ability of immunocompetent cells to migrate in a tissue specific fashion through the use of various chemokines and their receptors. Typical of the hijacking of an immune system component by a pathogen is the use of a chemokine ligand gene in the viral ancestor to SIV and HIV, allowing for virus binding to immunocompetent cells as is seen in the use of the CCR5 chemokine receptor by macrophage-tropic HIV strains. This thesis describes the allele and genotype frequencies for several TcR beta-chain variable segment polymorphisms in a population of MS patients compared with controls before and after stratification for HLA-DR15, polymorphism in the Apo-1 / Fas promoter, the DRB1 Val86/Val86 genotype, CCR5-delta32 and the HLA-DRA promoter. The thesis continues with CCR5-delta32 genotyping in IDDM, MS and SLE cohorts and then examines the question of the population of origin of the delta-32 allele of the CCR5 receptor for chemokine. Here, a case / control comparison of 122 RR-MS patients with 96 normal individuals was made for allele and genotype frequencies and for haplotypes formed by pairs of TCRB markers. Further analysis was made after HLA-DR15 stratification. Linkage disequilibrium was found between pairs of alleles of bv8s1, bv10s1, bv15s1 and bv3s1 loci in both patients and controls. In the RR-MS cohort, an increase in the allele frequency of bv8s1*2 was seen (p = 0.03) and the haplotype bv8s1*2 / bv3s1*1 was increased (p = 0.006), and both were found to be statistically significant. In the DR15-positive group, association between MS and TCRB was seen with the bv8s1*2 allele (p = 0.05) and the bv8s1*2 / bv10s1 haplotypes (p = 0.048), while the haplotype associations seen among the DR15-negative patients included the bv3s1*1 allele (bv10s1*1 / bv3s1*1, p = 0.022; bv8s1*2 / bv3s1*1, p = 0.048). While no associations were found after stratification for SDF1-3'A, Apo-1 / Fas or DRB1 there were modest interactions between bv3s1, bv10s1 and bv15s1 and the HLA-DRA promoter. These results support the involvement of the TCRB region in MS susceptibility. The further study of autoimmune disease here includes genotype analysis of CCR5-delta32 in type 1 diabetes (IDDM) and SLE. CCR5 is the major co-receptor for viral entry used by macrophage-tropic HIV strains and protection from infection is seen in homozygotes for CCR5-delta32. In diabetes, infiltration of pancreatic tissue by autoreactive T-cells involves secretion of multiple cytokines and chemokine receptor expression. Variation in the chemokine receptor CCR5 may result in differences in inflammatory cell migration in response to relevant chemokines. Adolescents with type 1 diabetes were genotyped for CCR5-delta32 (n = 626). The allele frequency was compared with that of 253 non-diabetic adolescents and with that of 92 adults with SLE. A reduced allele frequency was seen in type 1 diabetes compared with controls (0.092 vs 0.123, p = 0.05). This difference was not seen for the cohort of patients with SLE (freq = 0.114). A reduction in the number of CCR5-delta32/delta32 homozygotes, who lack CCR5, in the type 1 diabetes cohort was also seen and while not statistically significant (2 observed compared to 5.25 expected; p = 0.12) is interesting. These results suggest a partial protection from type 1 diabetes for CCR5-delta32 homozygous individuals is possible and that CCR5 has a potential role in the pathogenesis of type 1 diabetes. Global surveys of the CCR5-delta32 allele have confirmed a single mutation event in a Northeastern European population as the source of this allele. Here, Australian Ashkenazi Jews (n = 807) were found to have a CCR5-delta32 allele frequency of 14.6% while Australian Sephardic Jews (n = 35) had a frequency of 5.7% and non-Jewish Australian controls (n = 311) had an allele frequency of 11.25%. Data on birthplace of grandparents showed a gradient with highest CCR5-delta32 frequencies from Eastern European Ashkenazim (~19.5% for those whose four grandparents come only from Russia, Poland, Hungary, Austria and Czechoslovakia; n = 197) which differs significantly from the frequency seen in Ashkenazi Jews from Western Europe (n = 101, p = 0.001). Homozygotes for CCR5-delta32 were genotyped with 3p21 region microsatellites. This has defined an ancestral haplotype on which the mutation first occurred and helped to date this event to between 40 and 50 generations ago or just over a thousand years ago. The population gradient, combined with the dating of the mutation by microsatellite allele frequencies, suggests an origin for the CCR5-delta32 allele in a population ancestral to the Ashkenazim. The distribution in non-Jewish populations in northern Europe has led others to postulate spread of the mutation by Vikings. It is hypothesised here that the link between the two populations could be the kingdom of Khazaria with subsequent admixture into both Swedish Vikings and Ashkenazi Jews. The basic driving force of evolution is through selection and the immune system has a role which, through the survival pressure exerted by viruses and other pathogens, has the potential to exert a great deal of selective force on the various components of this system. The effects of this pronounced selection on an immune system component can be seen for example in the increase of the CCR5-delta32 allele over the last thousand years to the current frequency. As mentioned, some immune system components are not affected by such straightforward selection. In the case of the TCRBV segments, effects on the immune repertoire can occur through MHC interaction at the point of thymic entry and in the effects of various superantigens, but the actual binding pockets that recognise antigen are themselves unable to be selected for (or against). The findings presented in this thesis provide support for the association of TCRBV gene segments with multiple sclerosis and also provide support for the further study of the role of the CCR5-delta32 allele in type 1 diabetes. Furthermore, data presented here suggests that the CCR5-delta32 allele had an origin in the Khazar Kingdom just over a thousand years ago, accounting for the allele frequencies in both the Ashkenazi Jews and in lands frequented by the Vikings. The definition of an extended ancestral haplotype for the CCR5-delta32 allele shows how the effect of selection of an allele of one gene can carry with it specific alleles of a large number of other genes as well.
3

Genetics of the immune cell receptors TCRB and CCR5 in human disease

Buhler, Marc McWilliams January 2003 (has links)
Abstract Early in the evolution of the vertebrates it is thought that two genomic duplications occurred, providing a basis for the evolution in body plan and neural crest of very early vertebrates and substantive material for further evolution of various gene families such as those making up a number of components of the adaptive vertebrate immune system. While the bony fish possibly had another, genome duplications are not generally a feature of vertebrate evolution and indeed the appearance of an antigen-adaptive immune recognition system may have served to limit the size that various vertebrate genomes, including that of the human, can in fact achieve. This initial step in vertebrate immune evolution, the establishment of recognition of non-self against the unique set of 'self' epitopes for an individual, provided an immensely powerful weapon in immune function with the ability to tailor a defense against as-yet-unseen dangers at any time albeit with the pitfall of autoimmune disease. As the recognition sites of the antigen receptor molecules such as TcR are produced by clonal modification of the segments provided in the germline and are thus not in the genome itself, pathogens have not been able to hijack this one component of the immune system in the way so many other components have been put to use throughout evolution, nor do these components necessarily reveal themselves as associated with disease through genome screens. Importantly, overall immune function is determined not just by the potential repertoire of recognition receptors but also by the ability of immunocompetent cells to migrate in a tissue specific fashion through the use of various chemokines and their receptors. Typical of the hijacking of an immune system component by a pathogen is the use of a chemokine ligand gene in the viral ancestor to SIV and HIV, allowing for virus binding to immunocompetent cells as is seen in the use of the CCR5 chemokine receptor by macrophage-tropic HIV strains. This thesis describes the allele and genotype frequencies for several TcR beta-chain variable segment polymorphisms in a population of MS patients compared with controls before and after stratification for HLA-DR15, polymorphism in the Apo-1 / Fas promoter, the DRB1 Val86/Val86 genotype, CCR5-delta32 and the HLA-DRA promoter. The thesis continues with CCR5-delta32 genotyping in IDDM, MS and SLE cohorts and then examines the question of the population of origin of the delta-32 allele of the CCR5 receptor for chemokine. Here, a case / control comparison of 122 RR-MS patients with 96 normal individuals was made for allele and genotype frequencies and for haplotypes formed by pairs of TCRB markers. Further analysis was made after HLA-DR15 stratification. Linkage disequilibrium was found between pairs of alleles of bv8s1, bv10s1, bv15s1 and bv3s1 loci in both patients and controls. In the RR-MS cohort, an increase in the allele frequency of bv8s1*2 was seen (p = 0.03) and the haplotype bv8s1*2 / bv3s1*1 was increased (p = 0.006), and both were found to be statistically significant. In the DR15-positive group, association between MS and TCRB was seen with the bv8s1*2 allele (p = 0.05) and the bv8s1*2 / bv10s1 haplotypes (p = 0.048), while the haplotype associations seen among the DR15-negative patients included the bv3s1*1 allele (bv10s1*1 / bv3s1*1, p = 0.022; bv8s1*2 / bv3s1*1, p = 0.048). While no associations were found after stratification for SDF1-3'A, Apo-1 / Fas or DRB1 there were modest interactions between bv3s1, bv10s1 and bv15s1 and the HLA-DRA promoter. These results support the involvement of the TCRB region in MS susceptibility. The further study of autoimmune disease here includes genotype analysis of CCR5-delta32 in type 1 diabetes (IDDM) and SLE. CCR5 is the major co-receptor for viral entry used by macrophage-tropic HIV strains and protection from infection is seen in homozygotes for CCR5-delta32. In diabetes, infiltration of pancreatic tissue by autoreactive T-cells involves secretion of multiple cytokines and chemokine receptor expression. Variation in the chemokine receptor CCR5 may result in differences in inflammatory cell migration in response to relevant chemokines. Adolescents with type 1 diabetes were genotyped for CCR5-delta32 (n = 626). The allele frequency was compared with that of 253 non-diabetic adolescents and with that of 92 adults with SLE. A reduced allele frequency was seen in type 1 diabetes compared with controls (0.092 vs 0.123, p = 0.05). This difference was not seen for the cohort of patients with SLE (freq = 0.114). A reduction in the number of CCR5-delta32/delta32 homozygotes, who lack CCR5, in the type 1 diabetes cohort was also seen and while not statistically significant (2 observed compared to 5.25 expected; p = 0.12) is interesting. These results suggest a partial protection from type 1 diabetes for CCR5-delta32 homozygous individuals is possible and that CCR5 has a potential role in the pathogenesis of type 1 diabetes. Global surveys of the CCR5-delta32 allele have confirmed a single mutation event in a Northeastern European population as the source of this allele. Here, Australian Ashkenazi Jews (n = 807) were found to have a CCR5-delta32 allele frequency of 14.6% while Australian Sephardic Jews (n = 35) had a frequency of 5.7% and non-Jewish Australian controls (n = 311) had an allele frequency of 11.25%. Data on birthplace of grandparents showed a gradient with highest CCR5-delta32 frequencies from Eastern European Ashkenazim (~19.5% for those whose four grandparents come only from Russia, Poland, Hungary, Austria and Czechoslovakia; n = 197) which differs significantly from the frequency seen in Ashkenazi Jews from Western Europe (n = 101, p = 0.001). Homozygotes for CCR5-delta32 were genotyped with 3p21 region microsatellites. This has defined an ancestral haplotype on which the mutation first occurred and helped to date this event to between 40 and 50 generations ago or just over a thousand years ago. The population gradient, combined with the dating of the mutation by microsatellite allele frequencies, suggests an origin for the CCR5-delta32 allele in a population ancestral to the Ashkenazim. The distribution in non-Jewish populations in northern Europe has led others to postulate spread of the mutation by Vikings. It is hypothesised here that the link between the two populations could be the kingdom of Khazaria with subsequent admixture into both Swedish Vikings and Ashkenazi Jews. The basic driving force of evolution is through selection and the immune system has a role which, through the survival pressure exerted by viruses and other pathogens, has the potential to exert a great deal of selective force on the various components of this system. The effects of this pronounced selection on an immune system component can be seen for example in the increase of the CCR5-delta32 allele over the last thousand years to the current frequency. As mentioned, some immune system components are not affected by such straightforward selection. In the case of the TCRBV segments, effects on the immune repertoire can occur through MHC interaction at the point of thymic entry and in the effects of various superantigens, but the actual binding pockets that recognise antigen are themselves unable to be selected for (or against). The findings presented in this thesis provide support for the association of TCRBV gene segments with multiple sclerosis and also provide support for the further study of the role of the CCR5-delta32 allele in type 1 diabetes. Furthermore, data presented here suggests that the CCR5-delta32 allele had an origin in the Khazar Kingdom just over a thousand years ago, accounting for the allele frequencies in both the Ashkenazi Jews and in lands frequented by the Vikings. The definition of an extended ancestral haplotype for the CCR5-delta32 allele shows how the effect of selection of an allele of one gene can carry with it specific alleles of a large number of other genes as well.
4

Auschwitz has happened: an exploration of the past, present, and future of Jewish redemption

Marcus, Alexander Warren 24 April 2009 (has links)
Ch. 1: Introduction: A Destruction without Adequate Precedent. Ch. 2: Rupture and the Holy Ideal: Redemption in the Hebrew Bible. Ch. 3: Giving the Sense: The Rise of Commentary. Ch. 4: Rabbi Eliezer’s Silence. Ch. 5: Gold and Glass: Ethical Rupture in Mystical Union? Ch. 6: Our Impossible Victory.
5

Les pseudonymes dans les littératures yiddish et hébraïque du millieu du XIXe siècle au milieu du XXe siècle / Pseudonyms in Yiddish and Hebrew Literatures, from the Mid-19th Century to the Middle of the 20th Century

Bar-Kochva, Sharon 06 February 2015 (has links)
Les littératures yiddish et hébraïque modernes sont étroitement liées par une histoire commune et partagent également de multiples traits stylistiques et thématiques. Or, une différence importante peut être remarquée quant à l’usage des pseudonymes dans les deux langues. Dans la littérature yiddish moderne, la pseudonymie est très importante, aussi bien du point de vue quantitatif que qualitatif, et une grande partie des plus importants auteurs yiddish sont connus principalement sous leur pseudonyme, alors que dans la littérature hébraïque moderne les noms de plume restent un phénomène relativement marginal. La présente recherche analyse la pseudonymie dans les deux littératures, dans le but d’expliquer cet écart. Nous commençons par une analyse des modes de construction des pseudonymes pour en constituer une typologie générale. Par la suite, nous nous concentrons sur les pseudonymes « durables », c'est-à-dire ceux qui accompagnent les auteurs sur le long terme et façonnent leur image publique, pour décrire en détail dans quelles circonstances et de quelles manières ils sont utilisés. Enfin, nous utilisons les informations recueillies pour démontrer que la pseudonymie est un phénomène social, et pour isoler les facteurs sociaux et historiques qui ont conduit à l’adoption de la pseudonymie comme l’une des « traditions inventées » de la littérature yiddish moderne. / Modern Yiddish and Hebrew literatures are closely connected by a common long history, sharing many stylistic and thematic features. However, both literatures significantly differ in their use of pseudonyms. In Yiddish literature, authors’ pseudonyms appear rather frequently, and a significant number of the most important writers are known mainly in their pseudonyms, while in modern Hebrew literature pen names remained a relatively marginal occurrence. This research analyses pseudonymity in both literatures in order to explain this discrepancy. In the first chapter, the various patterns used in building pseudonyms are analysed, so to establish a general typology of the phenomenon. Subsequently, I focus on the "lasting" pseudonyms, namely those that accompany authors for a long time, shaping and determining their public image. In the second chapter I describe in detail under which circumstances and in what ways the "lasting" pseudonyms were created and used. Finally, in the last part the information analysed previously is utilised, clarifying that pseudonymity is actually a social phenomenon, and defining the social and historical factors that led to the adoption of pseudonymity as one of the "invented traditions" of modern Yiddish literature.
6

Inside/Outside/In-between: Understanding how Jewish Identity Impacts the Lives and Narratives of Ashkenazi Female Public School Educators

Benditson, Mindi Ellen 01 April 2016 (has links)
Since Ashkenazi Jews in the United States are not a visible minority, it often becomes difficult to distinguish what/who is a Jew. As many Jewish females may appear to be of the dominant culture, they often get overlooked in discussions and courses on teacher education and multiculturalism/multicultural education. However, their identity as both Jewish and White and the absence of conversation regarding their multiple positions in education and in society can contest, as well as support, their connection to multiculturalism. The purpose of this research was to identify how four middle class Ashkenazi females in the greater Los Angeles area understand their identities and experiences as Jews and as public school educators, how these multiple identities impact their perceptions of their pedagogy, and how these women navigate the structures of public schooling. Narrative Inquiry and Listening Guide method of analysis were utilized to present multilayered portraits of these women in order to challenge the status quo of the White female teacher identity and the positioning of Jewish females in regards to the perseverance of Christianity in public education. Story threads emerged from the narratives which indicated that while Jewish identity is fluid and exists on a continuum over time, it was not a primary reason why these women became teachers. Although each woman made individual decisions regarding the degree to which her Jewishness was presented in the classroom and on campus, they did not actively design their curriculum due to them being Jewish; rather they unconsciously incorporated aspects of Judaism in their pedagogy.
7

Auschwitz has Happened: An Exploration of the Past, Present, and Future of Jewish Redemption

Marcus, Alexander Warren 24 April 2009 (has links)
Ch. 1: Introduction: A Destruction without Adequate Precedent. Ch. 2: Rupture and the Holy Ideal: Redemption in the Hebrew Bible. Ch. 3: Giving the Sense: The Rise of Commentary. Ch. 4: Rabbi Eliezer’s Silence. Ch. 5: Gold and Glass: Ethical Rupture in Mystical Union? Ch. 6: Our Impossible Victory.
8

Prevalência do polimorfismo R72P no gene TP53 E C677T / A1298C do gene da metilenotetrahidrofolato redutase (MTHFR) em mulheres judias ashkenazi de Porto Alegre

Silva, Isabel Cristina Bandeira da January 2011 (has links)
A suscetibilidade ao câncer se apresenta com diferentes freqüências em diferentes populações. Dentre muitas das estudadas está a população judaica Ashkenazi, que vêm sendo alvo de muitos trabalhos por apresentarem doenças genéticas em proporção maior do que seria esperado para outra população qualquer. Tal incidência provavelmente advém do fato de terem sofrido dois grandes bottlenecks ao longo de sua história, gerando um efeito fundador que seria responsável pela alta incidência de doenças genéticas. O gene TP53 tem papel importante em um grande número de processos celulares e o polimorfismo Arg72Pro (R72P) deste gene leva a diferenças funcionais em atividades biológicas e bioquímicas, o que parece estar intimamente ligado ao câncer de mama. Da mesma forma, acredita-se que a variação genética de genes para metilenotetrahidrofolato redutase (MTHFR), enzima essencial no metabolismo um-carbono, pode alterar os níveis de metilação do DNA e influenciar a carcinogênese. Buscou-se então verificar qual a prevalência do polimorfismo R72P e dos polimorfismos de MTHFR (A1298C e C677T) em mulheres judias Ashkenazi de Porto Alegre. Para isto, foi utilizado material biológico proveniente de 255 mulheres Ashkenazi residentes na cidade de Porto Alegre e 255 amostras de um grupo controle de doadores saudáveis do hospital de clínicas de Porto Alegre, para amplificação das regiões de interesse através da técnica de PCR seguida por digestão com enzimas de restrição específicas. O polimorfismo R72P mostrou uma freqüência genotípica de ~61% Arg/Arg, ~37% Arg/Pro e ~2% Pro/Pro nas mulheres judaicas Ashkenazi; em comparação com a amostra controle que mostrou uma freqüência genotípica de ~43% Arg/Arg, ~44% Arg/Pro e 13% Pro/Pro. Com relação aos polimorfismos de MTHFR, obteve-se os seguintes resultados para judias e controles, respectivamente: 677CC (31 e 42%), 677CT (47 e 48%), 677TT (22 e 10%), 1298AA (49,4 e 60%), 1298AC (43,1 e 35%) e 1298CC (7,5 e 5%). Os resultados estatísticos mostraram-se significativos para as freqüências alélicas e genotípicas (P<0,001 para R72P; P=0,000 para C677T e P=0,041 para A1298C). Ampliar e diversificar as amostras se faz necessário para avaliar consistentemente como a influência das diferenças étnicas e raciais podem afetar os resultados dos estudos, além de aspectos como alimentação, fumo, hábito de beber, casamentos consangüíneos, entre outros, devem ser considerados nas análises de dados, buscando uma melhor resposta em relação às hipóteses levantadas e assim eliminando da análise possíveis fatores de confusão. / Cancer susceptibility is presented with different frequencies in different populations. Among the many populations studied, the Ashkenazi Jewish have been the subject of several scientific publications due to the greater proportion of genetic diseases observed than would be expected for any other population. This effect probably stands from the fact that they had suffered two major bottlenecks throughout its history, resulting in a founder effect that would be responsible for high incidence of genetic diseases. TP53 gene has an important role in many cellular processes and the Arg72Pro (R72P) polymorphism of this gene leads to functional differences in biochemical and biological activities, which seems to be closely linked to breast cancer. It is also believed that the genetic variation of genes for methylenetetrahydrofolate reductase (MTHFR), an essential enzyme of the one-carbon metabolism, can alter levels of DNA methylation and influence carcinogenesis. We sought to determine how prevalent are R72P and MTHFR (C677T; A1298C) polymorphisms in a group of Ashkenazi Jewish women from Porto Alegre. For this, we used biological material from 255 Ashkenazi women living in Porto Alegre and 255 samples from a control group of healthy donors of Hospital de Clinicas de Porto Alegre, for amplification of interest regions by PCR followed by digestion with specific restriction enzymes. The R72P polymorphism showed a genotype frequency of ~ 61% Arg / Arg, ~ 37% Arg / Pro and ~ 2% Pro / Pro in the Ashkenazi Jewish, compared to the control sample which showed a genotype frequency of ~ 43% Arg /Arg, Arg ~ 44% / 13% Pro and Pro / Pro. Regarding the MTHFR polymorphisms we obtained the following results for Jewish and controls, respectively: 677CC (31 and 42%), 677CT (47 and 48%), 677TT (22 and 10%), 1298AA (49.4 and 60%), 1298AC (43.1 and 35%) and 1298CC (7.5 and 5%). The statistical results were significant for allele and genotype frequencies (P <0.001 for R72P, P = 0.000 for C677T and A1298C to P = 0.041). Increasing the sample number and studying several worldwide populations is needed to consistently evaluate the influence of ethnic and racial differences which may affect the results obtained. In addition to that, aspects such as diet, smoking, drinking, consanguineous marriages, among others, should be considered in the data analysis in order to seek for a better response to the hypotheses raised, thus eliminating possible confounding factors.
9

Prevalência do polimorfismo R72P no gene TP53 E C677T / A1298C do gene da metilenotetrahidrofolato redutase (MTHFR) em mulheres judias ashkenazi de Porto Alegre

Silva, Isabel Cristina Bandeira da January 2011 (has links)
A suscetibilidade ao câncer se apresenta com diferentes freqüências em diferentes populações. Dentre muitas das estudadas está a população judaica Ashkenazi, que vêm sendo alvo de muitos trabalhos por apresentarem doenças genéticas em proporção maior do que seria esperado para outra população qualquer. Tal incidência provavelmente advém do fato de terem sofrido dois grandes bottlenecks ao longo de sua história, gerando um efeito fundador que seria responsável pela alta incidência de doenças genéticas. O gene TP53 tem papel importante em um grande número de processos celulares e o polimorfismo Arg72Pro (R72P) deste gene leva a diferenças funcionais em atividades biológicas e bioquímicas, o que parece estar intimamente ligado ao câncer de mama. Da mesma forma, acredita-se que a variação genética de genes para metilenotetrahidrofolato redutase (MTHFR), enzima essencial no metabolismo um-carbono, pode alterar os níveis de metilação do DNA e influenciar a carcinogênese. Buscou-se então verificar qual a prevalência do polimorfismo R72P e dos polimorfismos de MTHFR (A1298C e C677T) em mulheres judias Ashkenazi de Porto Alegre. Para isto, foi utilizado material biológico proveniente de 255 mulheres Ashkenazi residentes na cidade de Porto Alegre e 255 amostras de um grupo controle de doadores saudáveis do hospital de clínicas de Porto Alegre, para amplificação das regiões de interesse através da técnica de PCR seguida por digestão com enzimas de restrição específicas. O polimorfismo R72P mostrou uma freqüência genotípica de ~61% Arg/Arg, ~37% Arg/Pro e ~2% Pro/Pro nas mulheres judaicas Ashkenazi; em comparação com a amostra controle que mostrou uma freqüência genotípica de ~43% Arg/Arg, ~44% Arg/Pro e 13% Pro/Pro. Com relação aos polimorfismos de MTHFR, obteve-se os seguintes resultados para judias e controles, respectivamente: 677CC (31 e 42%), 677CT (47 e 48%), 677TT (22 e 10%), 1298AA (49,4 e 60%), 1298AC (43,1 e 35%) e 1298CC (7,5 e 5%). Os resultados estatísticos mostraram-se significativos para as freqüências alélicas e genotípicas (P<0,001 para R72P; P=0,000 para C677T e P=0,041 para A1298C). Ampliar e diversificar as amostras se faz necessário para avaliar consistentemente como a influência das diferenças étnicas e raciais podem afetar os resultados dos estudos, além de aspectos como alimentação, fumo, hábito de beber, casamentos consangüíneos, entre outros, devem ser considerados nas análises de dados, buscando uma melhor resposta em relação às hipóteses levantadas e assim eliminando da análise possíveis fatores de confusão. / Cancer susceptibility is presented with different frequencies in different populations. Among the many populations studied, the Ashkenazi Jewish have been the subject of several scientific publications due to the greater proportion of genetic diseases observed than would be expected for any other population. This effect probably stands from the fact that they had suffered two major bottlenecks throughout its history, resulting in a founder effect that would be responsible for high incidence of genetic diseases. TP53 gene has an important role in many cellular processes and the Arg72Pro (R72P) polymorphism of this gene leads to functional differences in biochemical and biological activities, which seems to be closely linked to breast cancer. It is also believed that the genetic variation of genes for methylenetetrahydrofolate reductase (MTHFR), an essential enzyme of the one-carbon metabolism, can alter levels of DNA methylation and influence carcinogenesis. We sought to determine how prevalent are R72P and MTHFR (C677T; A1298C) polymorphisms in a group of Ashkenazi Jewish women from Porto Alegre. For this, we used biological material from 255 Ashkenazi women living in Porto Alegre and 255 samples from a control group of healthy donors of Hospital de Clinicas de Porto Alegre, for amplification of interest regions by PCR followed by digestion with specific restriction enzymes. The R72P polymorphism showed a genotype frequency of ~ 61% Arg / Arg, ~ 37% Arg / Pro and ~ 2% Pro / Pro in the Ashkenazi Jewish, compared to the control sample which showed a genotype frequency of ~ 43% Arg /Arg, Arg ~ 44% / 13% Pro and Pro / Pro. Regarding the MTHFR polymorphisms we obtained the following results for Jewish and controls, respectively: 677CC (31 and 42%), 677CT (47 and 48%), 677TT (22 and 10%), 1298AA (49.4 and 60%), 1298AC (43.1 and 35%) and 1298CC (7.5 and 5%). The statistical results were significant for allele and genotype frequencies (P <0.001 for R72P, P = 0.000 for C677T and A1298C to P = 0.041). Increasing the sample number and studying several worldwide populations is needed to consistently evaluate the influence of ethnic and racial differences which may affect the results obtained. In addition to that, aspects such as diet, smoking, drinking, consanguineous marriages, among others, should be considered in the data analysis in order to seek for a better response to the hypotheses raised, thus eliminating possible confounding factors.
10

Les pseudonymes dans les littératures yiddish et hébraïque du milieu du XIXe siècle au milieu du XXe siècle / Pseudonyms in Yiddish and Hebrew Literatures, from the Mid-19th Century to the Middle of the 20th Century

Bar-Kochva, Sharon 06 February 2015 (has links)
Les littératures yiddish et hébraïque modernes sont étroitement liées par une histoire commune et partagent également de multiples traits stylistiques et thématiques. Or, une différence importante peut être remarquée quant à l’usage des pseudonymes dans les deux langues. Dans la littérature yiddish moderne, la pseudonymie est très importante, aussi bien du point de vue quantitatif que qualitatif, et une grande partie des plus importants auteurs yiddish sont connus principalement sous leur pseudonyme, alors que dans la littérature hébraïque moderne les noms de plume restent un phénomène relativement marginal. La présente recherche analyse la pseudonymie dans les deux littératures, dans le but d’expliquer cet écart. Nous commençons par une analyse des modes de construction des pseudonymes pour en constituer une typologie générale. Par la suite, nous nous concentrons sur les pseudonymes « durables », c'est-à-dire ceux qui accompagnent les auteurs sur le long terme et façonnent leur image publique, pour décrire en détail dans quelles circonstances et de quelles manières ils sont utilisés. Enfin, nous utilisons les informations recueillies pour démontrer que la pseudonymie est un phénomène social, et pour isoler les facteurs sociaux et historiques qui ont conduit à l’adoption de la pseudonymie comme l’une des « traditions inventées » de la littérature yiddish moderne. / Modern Yiddish and Hebrew literatures are closely connected by a common long history, sharing many stylistic and thematic features. However, both literatures significantly differ in their use of pseudonyms. In Yiddish literature, authors’ pseudonyms appear rather frequently, and a significant number of the most important writers are known mainly in their pseudonyms, while in modern Hebrew literature pen names remained a relatively marginal occurrence. This research analyses pseudonymity in both literatures in order to explain this discrepancy. In the first chapter, the various patterns used in building pseudonyms are analysed, so to establish a general typology of the phenomenon. Subsequently, I focus on the "lasting" pseudonyms, namely those that accompany authors for a long time, shaping and determining their public image. In the second chapter I describe in detail under which circumstances and in what ways the "lasting" pseudonyms were created and used. Finally, in the last part the information analysed previously is utilised, clarifying that pseudonymity is actually a social phenomenon, and defining the social and historical factors that led to the adoption of pseudonymity as one of the "invented traditions" of modern Yiddish literature.

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