The thesis is focused on creation of B2B market place design to support small and medium size enterprises. It is based on research of issues of small and medium size enterprises and system complexity. Study of logistics, logistic distribution and contemporary supply chains in the Czech Republic from the point of view of small and medium size enterprises is another part of the thesis. The design is based on research of semantic web and is created according to MMSP methodology. The design is created to eliminate pressure points of studied areas such as small ability of semantic web to become a communication system used in exchange of enterprises' offers and demands, limited cooperation of small and medium enterprises, prices which do not depend on logistics costs and door to door deliveries which supports the prominent position of large retail companies.