This work tries to describe the possibility of implementation of Protocol NISO Circula-tion Interchange Protocol. In the theoretical part will be mentioned the history, structure and importance of the protocol. There will also be mentioned the mark-up language XML and protocol HTTP. In the practical part will be created application in C # which com-municates through NCIP protocol. The XML processing ensures XmlSerializer class. For testing will be modified NCIP V2 Dummy Responder, which uses Java XC NCIP Toolkit.