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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
301

The DNA-damaging effect of bile acids and the protective effect of cellulose.

Cheah, Peh Yean. January 1989 (has links)
Colon cancer is the second most common type of cancer in the United States. Its incidence is linked epidemiologically to high levels of bile acids in the feces. Bile acids have been implicated as promotors and cocarcinogens in the etiology of colon cancer and as comutagens and mutagens in bacteria. These observations suggest the hypothesis that bile acids may interact directly with DNA. Using agarose gel electrophoresis we showed that bile acids convert covalently closed circular plasmid DNA to the open circular form, indicating strand breakage. We next treated the single stranded circular DNA of phage M13 with bile acids and found that the transfection efficiency of this DNA declined up to a thousand-fold. The concentrations of bile acids used were of the same magnitude as the fecal bile acid concentrations found in colorectal cancer patients. This inactivation was largely prevented when the bile acids were pretreated with cellulose fiber.
302

An investigation into different responses of a Pakistani biotype of Callosobruchus maculatus (Bruchidae: Coleoptera) to four new varieties of pulses from Pakistan

Sulehrie, Mohammad Abid Qaiyum January 2000 (has links)
No description available.
303

A study of graphoepitaxially grown Al and Cu interconnects

Weaver, David John January 1998 (has links)
No description available.
304

Abiotic stress effects in potato (Solanum tuberosum L.) and sweet potato (Ipomoea batatas [L.] Lam.)

Richardson, Kenneth Vincent Austin January 2000 (has links)
No description available.
305

Analysis of gene regulation by mycobacterium tuberculosis LexA

Dullaghan, Edith Mary January 2000 (has links)
No description available.
306

Inducible tolerance and sensitivity to stress responses in 'Escherichia coli' with particular reference to copper and pH

Hussain, Noor Hana January 1996 (has links)
No description available.
307

Characterisation of the RuvB branch migration motor

George, Helen Marion January 2000 (has links)
No description available.
308

The mechanism by which hyperammonaemia may cause hepatic encephalopathy

Smart, Kevin Arthur January 1997 (has links)
No description available.
309

Mechanisms of regulation of liver metabolism and growth

Marker, Alison Jean January 1998 (has links)
No description available.
310

The evaluation of p53 function in cells from members of cancer prone families

Lomax, Martine Elizabeth January 1998 (has links)
No description available.

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