by Ka-Fai Ng. / Thesis (M.Phil.)--Chinese University of Hong Kong, 1999. / Includes bibliographical references (leaves 51-54). / Abstracts in English and Chinese. / Contents --- p.i / Acknowledgments --- p.iii / Abstract --- p.iv / Abbreviations --- p.vi / Chapter Chapter I --- Introduction / Chapter I-1 --- General background of dendrimers --- p.1 / Chapter I-2 --- Synthesis of dendritic molecules --- p.2 / Chapter I-2-1 --- Divergent methods --- p.2 / Chapter I-2-2 --- Convergent methods --- p.4 / Chapter Chapter II --- Functional dendrimers / Chapter II-1 --- Catalytically active dendrimers --- p.8 / Chapter II-2 --- Polyhydrocarbon-based dendrimers --- p.17 / Chapter Chapter III --- Results and Discussion / Chapter III-1 --- Solvent dependence of the rate of Diels-Alder reaction --- p.23 / Chapter III-2 --- Synthesis and characterization of polyhydrocarbon-based dendritic fragments --- p.25 / Chapter III-2-1 --- Architecture of the dendritic fragments --- p.25 / Chapter III-2-2 --- The iterative cycle --- p.27 / Chapter III-2-3 --- Synthesis of GO dendrimer --- p.28 / Chapter III-2-4 --- Construction of G1 dendrimers --- p.29 / Chapter III-2-5 --- Construction of the G2 dendrimers --- p.31 / Chapter III-3 --- Conclusions --- p.36 / Chapter Chapter IV --- Summary --- p.37 / Chapter Chapter V --- Experimental --- p.38 / References --- p.51 / Spectra --- p.55

by Pui-Shan Fung. / Thesis submitted in: December 1999. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2000. / Includes bibliographical references (leaves 67-69). / Abstracts in English and Chinese. / Acknowledgments --- p.ii / Abstract --- p.iii / Abbreviations --- p.v / Chapter Chapter I. --- Introduction / Chapter 1. --- General background of dendrimers --- p.1 / Chapter 2. --- Metallodendrimers --- p.4 / Chapter 3. --- Fluorinated dendrimers --- p.12 / Chapter Chapter II. --- Synthesis and characterization / Chapter 1. --- Structure of the dendritic fragments --- p.15 / Chapter 2. --- Synthesis of the terpy-based metallodendrimers --- p.16 / Chapter 3. --- Characterization / Chapter 3.1 --- Characterization of fluorinated dendrimers --- p.31 / Chapter 3.2 --- Characterization of non-fluorinated dendrimers --- p.36 / Chapter Chapter III. --- Redox properties of metallodendrimers / Chapter 1. --- Cyclic voltammetric studies --- p.38 / Chapter 1.1 --- Cyclic voltammograms of fluorinated metallodendrimers --- p.40 / Chapter 1.2 --- Cyclic voltammograms of non-fluorinated metallodendrimers --- p.44 / Chapter Chapter IV. --- Summary --- p.47 / Chapter Chapter V. --- Experimental --- p.49 / References --- p.67 / Spectra --- p.70

by Vincent Yam-Fat Lau. / Thesis submitted in: November 1998. / Thesis (M.Phil.)--Chinese University of Hong Kong, 1999. / Includes bibliographical references (leaves 53-57). / Abstract also in Chinese. / Contents --- p.i / Acknowledgments --- p.ii / Publication --- p.iii / Abstract --- p.iv / Abbreviations --- p.vi / Chapter Chapter I. --- Introduction / Chapter 1. --- General background of synthetic chemistry in dendrimers --- p.1 / Chapter 2. --- Accelerated approaches --- p.5 / Chapter Chapter II. --- Synthesis and Characterization / Chapter 1. --- Structure of the dendritic fragments --- p.17 / Chapter 2. --- Synthesis of the dendritic fragments --- p.18 / Chapter 3. --- Characterization --- p.26 / Chapter Chapter III. --- Attempted Synthesis of Electrochemically Active Metallodendrimers / Chapter 1. --- Background --- p.30 / Chapter 2. --- Synthesis of a ferrocene containing spacer for the construction of metallodendrimers containing multiple redox active units --- p.35 / Chapter 3. --- Conclusions --- p.41 / Chapter Chapter IV. --- Summary --- p.42 / Chapter Chapter V. --- Experimental --- p.43 / References --- p.53 / Spectra --- p.58

The synthetic efficacy of the dendrimer backbone rearrangement was examined by conducting heterogeneous Ramburg-Backlund rearrangements (alumina supported KOH, CBr2F2/THF/t-BuOH = 1/1/1) on dibenzylsulfone G3-CCSO2-dendrimer 141 and G3-CSO2C-dendrimer 142. Again, steric inhibition was found to play a prominent role in dictating the chemical reactivity of the sulfone moieties under heterogeneous conditions. The innermost sulfones in compound 141 were found to be relatively inert and at most only 1 out of the 3 sulfones could undergo the rearrangement, and the major product was the starting material. On the other hand, up to 3 or 4 of the intermediate layer sulfone moieties underwent the rearrangement reaction to give the triene-tris(sulfone) 145 or tetraene-bis(sulfone) 144 products. For the first time in the literature, conclusive mass spectral evidence was obtained to unveil the detailed outcome of such complex dendrimer backbone rearrangement reactions. / The synthetic efficiency of the dendrimer interior functional group conversion method was exemplified by converting the dibenzyl sulfide moieties in G3-CCS-dendrimer 68 and G3-CSC-dendrimer 69 to the corresponding dibenzyl sulfone under either heterogeneous (oxone in CH2Cl2) or homogeneous (35% H2O2 in CH2Cl2/HOAc) conditions. The effect of steric inhibition was prominent under the heterogeneous conditions as the solid oxone particles failed to penetrate into the dendrimer interior to initiate the oxidation reaction. On the other hand, dendrimers 68, 69 and 136 could be oxidized to the corresponding dibenzyl sulfones via the dibenzyl sulfoxides under homogeneous conditions. For the first oxidation to the dibenzyl sulfoxides, both compounds 68 and 69 proceeded with similar speed, indicating the similar steric environment between the innermost and intermediate layers of dibenzylsulfide moieties. On the other hand, the innermost dibenzyl sulfoxides in compound 68, in comparison to the dibenzyl sulfoxides in the middle layer in compound 69, underwent further oxidation to the dibenzyl sulfones with greater ease. This finding suggested that there were other factors, in addition to steric inhibition, in controlling the chemical reactivity of functional groups inside the dendrimer matrix. Our speculation was that the microenvironment polarity of the dendrimer interior could also play an important role in facilitating/retarding the diffusion of external chemical reagents into the interior of the dendrimer. / Two layer-block G3-CCS-dendrimer 68 and G3-CSC-dendrimer 69 with dibenzylsulfide functionalities embedded in the innermost and intermediate dendritic layers, respectively, were synthesized by a convergent method. The key steps involved in their constructions were Horner-Wadsworth-Emmons olefination and thiol-mediated alkylation reaction. A third target G3-SCC-dendrimer 70, with dibenzylsulfide moieties located in the outermost dendritic layer, could not be synthesized despite many attempts. A fourth model G3-SSS-dendrimer 136 containing 21 dibenzyl sulfone moieties in the innermost, middle and outermost layers was also prepared. All synthesized compounds were characterized by 1H and 13C nuclear magnetic resonance spectroscopy, mass spectrometry, elemental analysis and/or size exclusion chromatography. They were prepared in order to probe the feasibility of and the effect of dendritic shielding on two novel dendrimer synthesis methodologies, namely, dendrimer interior functional group conversion and dendrimer backbone rearrangement. / Cheng, Wing Sum. / Adviser: H. F. Chow. / Source: Dissertation Abstracts International, Volume: 73-01, Section: B, page: . / Thesis (Ph.D.)--Chinese University of Hong Kong, 2010. / Includes bibliographical references (leaves 117-124). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [201-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstract also in Chinese.

by Mong Kwok Kong Tony. / Thesis (Ph.D.)--Chinese University of Hong Kong, 2000. / Includes bibliographical references (p. 95-101). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Mode of access: World Wide Web. / Abstracts in English and Chinese.

by Chi-Wing Leung. / Thesis (M.Phil.)--Chinese University of Hong Kong, 1999. / Includes bibliographical references (leaves 56-58). / Abstract also in Chinese. / Contents --- p.i / Acknowledgments --- p.ii / Abstract --- p.iii / Abbreviations --- p.v / Chapter Chapter I. --- Introduction / Chapter 1. --- Synthesis of Dendrimer --- p.2 / Chapter 2. --- The Ramberg-Backlund rearrangement --- p.9 / Chapter 3. --- Poly(phenylenevinylene) Dendrimer --- p.11 / Chapter Chapter II. --- "Synthesis, Results and Discussion" / Chapter 1. --- Synthesis --- p.15 / Chapter 2. --- Results and Discussion --- p.18 / Chapter Chapter III. --- Characterization / Chapter 1. --- Nuclear Magnetic Resonance Spectroscopy --- p.32 / Chapter 2. --- Ultra-Violet Spectroscopy --- p.36 / Chapter 3. --- Size Exclusion Chromatography --- p.36 / Chapter 4. --- Mass Spectrometry --- p.38 / Chapter Chapter IV. --- Conclusion --- p.40 / Chapter Chapter V. --- Experimental --- p.41 / References --- p.56 / Spectra --- p.59

Joseph Chung-Yin Lam. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2000. / Includes bibliographical references (leaves 62-64). / Abstracts in English and Chinese. / Contents --- p.i / Acknowledgements --- p.ii / Abstract --- p.iii / Abbreviations --- p.v / Chapter Chapter I. --- Introduction / Chapter (1) --- General background of dendrimers --- p.1 / Chapter (2) --- Electrochemically active dendrimers --- p.2 / Chapter (3) --- Electrochemically active dendrimers as models for studying the redox behaviour of complex proteins --- p.11 / Chapter Chapter II --- . Synthesis and Characterization / Chapter (1) --- Structure of the electrochemically active dendrimers --- p.16 / Chapter (2) --- Retrosynthetic analysis --- p.17 / Chapter (3) --- Synthesis --- p.18 / Chapter (4) --- Structural Characterization --- p.26 / Chapter (5) --- Conclusion --- p.33 / Chapter Chapter III. --- Physical and Electrochemical Properties / Chapter (1) --- Physical appearance and solubility properties --- p.34 / Chapter (2) --- Cyclic voltammetry studies --- p.34 / Chapter Chapter IV. --- Summary --- p.40 / Chapter Chapter V. --- Experimental --- p.41 / References --- p.62 / Spectra --- p.65

Wong Chun Ho. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2006. / Includes bibliographical references (leaves 72-77). / Abstracts in English and Chinese. / Contents --- p.i / Acknowledgments --- p.iii / Abstract --- p.iv / Abbreviations and acronyms --- p.vi / Publications originated from the work of this thesis --- p.viii / Chapter Chapter 1 - --- Dendritic Macromolecules and Dendronized Polymers / Chapter 1.1 --- Introduction to Dendrimers and Dendronized Polymers --- p.1 / Chapter 1.2 --- Overview of the Synthesis of Dendronized Polymers --- p.4 / Chapter 1.2.1 --- Graft-from Approach --- p.4 / Chapter 1.2.2 --- Graft-to Approach --- p.5 / Chapter 1.2.3 --- Macromonomer Approach --- p.6 / Chapter 1.2.3.1 --- Step Growth Polymerization --- p.6 / Chapter 1.2.3.2 --- Chain Growth Polymerization --- p.8 / Chapter 1.2.3.3 --- Supramolecular Polymerization --- p.9 / Chapter Chapter 2 - --- En Route to Hydrogen Bond-Mediated. Supramolecular Dendronized Polymers / Chapter 2.1 --- Design of Supramolecular Dendronized Polymers --- p.15 / Chapter 2.1.1 --- Binding Modes in Supramolecular Polymers --- p.15 / Chapter 2.1.1.1 --- Hetero-Complementary Polymerization --- p.16 / Chapter 2.1.1.2 --- Self-Complementary Polymerization --- p.17 / Chapter 2.1.2 --- The Effect of Binding Constant on the Degrees of Polymerization --- p.18 / Chapter 2.1.3 --- The Effect of Dimerization Constant on the Molecular Weight Distribution --- p.21 / Chapter 2.1.4 --- The Dendritic Effect on the UPy Binding Behavior --- p.21 / Chapter 2.2 --- Summary --- p.24 / Chapter Chapter 3 - --- "Design, Synthesis, and Structural Characterization of Dendronized Dimers" / Chapter 3.1 --- Design of Dendronized Dimers --- p.25 / Chapter 3.1.1 --- The Nature of R and R on the Dimerization Behavior --- p.25 / Chapter 3.1.2 --- Selection of Dendrons --- p.26 / Chapter 3.1.3 --- Positioning of Dendrons and the Synthetic Feasibility --- p.27 / Chapter 3.2 --- Synthesis of Dendronized Dimers --- p.28 / Chapter 3.3 --- Characterizations of the Intermediates and Target Dimers --- p.31 / Chapter 3.3.1 --- 1H NMR Spectroscopy --- p.31 / Chapter 3.3.2 --- 13C NMR Spectroscopy --- p.38 / Chapter 3.3.3 --- Mass Spectrometry --- p.41 / Chapter 3.3.4 --- Vapor Pressure Osmometry --- p.43 / Chapter 3.3.5 --- Infrared Spectroscopy --- p.43 / Chapter 3.3.6 --- Gel Permeation Chromatography --- p.44 / Chapter 3.4 --- Conclusions --- p.46 / Chapter Chapter 4 - --- Determination of Dimerization Constants / Chapter 4.1 --- Overview of the Self-Assembling Process in UPy System --- p.47 / Chapter 4.2 --- Determination of the Dimerization Constants (Kdim*) --- p.49 / Chapter 4.2.1 --- Dimerization Constants in CDCl3 at 25 °C --- p.50 / Chapter 4.2.2 --- Dimerization Constants in 10% (v/v) DMSO-d6/CDCl3 at 25 °C --- p.53 / Chapter 4.2.3 --- Dimerization Constants in CDCl3 at 50 °C --- p.56 / Chapter 4.3 --- Heterodimerization Experiment --- p.56 / Chapter 4.4 --- Conclusions --- p.57 / Chapter Chapter 5 - --- Experimental Procedures / Chapter 5.1 --- General Information --- p.60 / Chapter 5.2 --- General Synthetic Procedures --- p.61 / Chapter 5.3 --- Experimental Procedures --- p.62 / References --- p.72 / Appendix / NMR Spectra --- p.78 / GPC results --- p.119

by Chi-wai Wan. / Thesis (Ph.D.)--Chinese University of Hong Kong, 1999. / Includes bibliographical references (p. 129-136). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Mode of access: World Wide Web. / Abstracts in English and Chinese.

本論文敘述了 III-B類輪烷樹狀物的人工合成及其表徵。透過重覆(1) 經改良的 銅(I) 催化炔烴 -疊氮偶極環加成反應 (2) 生成醯胺鍵以及最後 (3) 格拉澤 -希偶聯反應合成第一代 (G1) 及第二初代 (G2 ’)IIIB類輪烷樹狀物。 銨鹽啞及冠醚被採用來組合成分支結構的偽輪烷。 III B類輪烷樹狀物被核磁共振波譜法及電噴霧離子化法－質譜所表徵。這項研究為 III-B類輪烷樹狀物合成研究提供不可或缺的雛型 。這項研究為超分子及高化學家開拓新的領域，給予他們研究III-B類輪烷樹狀物的特性及其生醫學和電子應用機會。 / In this thesis, the syntheses and characterizations of a series of Type III-B Rotaxane Dendrimers are described. First generation (G1) and prototypical second generation (G2’) Type IIIB Rotaxane Dendrimer, which incorporate rotaxane features as the branching units, were synthesized by employing consecutive (1) modified Copper-Catalyzed Alkyne-Azide Cycloaddition (CuAAC), (2) amide formation through stopper molecule and pseudorotaxanes, and (3) GlaserHay’s acetylene homo-coupling reaction. Pseudorotaxanes with ammonium thread and crown ether macrocycle were employed. The Type III-B Rotaxane Dendrimers were characterized by nuclear magnetic resonance (NMR) spectroscopy, electrospray ionisationmass spectrometry (ESI-MS). This study provides an indispensable prototype to the synthesis of novel Type III-B Rotaxane Dendrimer. It opened up great opportunity for supramolecular and polymer chemists to further explore the properties and biomedical and electronic application of the novel dendrimers. / Detailed summary in vernacular field only. / Ho, Kwok Wai. / "October 2012." / Thesis (M.Phil.)--Chinese University of Hong Kong, 2013. / Includes bibliographical references (leaves 49-51). / Abstracts also in Chinese. / Contents --- p.i / Acknowledgments --- p.ii / Abstract --- p.iii / Abbreviations and Acronyms --- p.v / Synthetic Studies Towards Type III-B Rotaxane Dendrimer / Chapter Chapter 1 --- Introduction / Chapter 1.1 --- Classification of Rotaxane Dendrimers --- p.2 / Chapter 1.2 --- Type II-B Rotaxane Dendrimer --- p.5 / Chapter 1.3 --- Application of Copper Catalyzed Alkyne Azide Cycloaddtion(CuAAC) in Rotaxane Synthesis --- p.8 / Chapter 1.4 --- Potential Application of Type III-B Rotaxane Dendrimer --- p.12 / Chapter 1.5 --- Aim of Project --- p.14 / Chapter Chapter 2 --- Synthetic Studies Towards of Type III-B Rotaxane Dendrimer / Chapter 2.1 --- Design and Synthesis of Type III-B Rotaxane Dendrimer --- p.15 / Chapter 2.2 --- Characterization of G1 and G2’ Type III-B Rotaxane Dendron/Dendrimer --- p.27 / Chapter 2.2.1 --- ¹H NMR Spectroscopy --- p.27 / Chapter 2.2.2 --- ¹³C NMR Spectroscopy --- p.32 / Chapter 2.2.3 --- Mass Spectrometry --- p.32 / Chapter 2.3 --- Conclusion --- p.38 / Chapter Chapter 3 --- Experimental Procedures / Chapter 3.1 --- General Information --- p.39 / Chapter 3.2 --- Experimental Procedures --- p.40 / References / Appendix / List of Spectra --- p.A1