Thesis (M.S.)--University of Wisconsin--Madison. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 131-141).

Thesis (M.S.)--University of Wisconsin--Madison. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 48-54).

Thesis (M.S.)--University of Wisconsin--Madison, 1981. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references.

Thesis--Wisconsin. / Includes bibliographical references (leaves 34-36).

No description available.

No description available.

No description available.

The design and synthesis of two heterocyclic thioanalogues of 7-deoxy daunomycinone, 9-acetyl-6,9,11-trihydroxythioxantho{2,3-g}- and -{3,2-g}tetralin, was accomplished. Various synthetic methodologies to accomplish this were evaluated and two key steps necessary for this synthesis were developed. The first consisted of a novel annulative synthetic sequence utilizing a biacetyl synthon, 3,3-diethoxy-2-butanone cyclohexylimine, and an ortho bis-halomethylarene. The second consisted of the use of o-chlorosulfenylbenzoyl chloride as a thiosalicyclic acid equivalent. Model studies toward the further elaboration of these 7-deoxy aglycones to the active glycosides were also studied. / In addition, 1-{{2-{(2-dydroxyethyl)amino}ethyl}amino}-4-hydroxythioxanthone was prepared and found not to have antitumor properties against P-388 leukemia in vivo.

Tübingen, Univ., Diss., 2002.

Universiẗat, Diss., 2006--Frankfurt (Main).