611 |
Time dependent characteristics in tablet compactionHo, A. Y. K. January 1986 (has links)
A single punch tablet machine has been instrumented to measure top and bottom punch force and punch displacement. A system has been developed for instrumenting rotary tablet machines using radio telemetery techniques and compared with conventional instrumentation systems. It is shown that the positioning of the measuring devices is critical for accurate measurements of forces and punch displacement. Samples of Micro crystalline cellulose (Avicel PH-102) and various grades of Lactose have been characterised and their compaction properties measured by a variety of techniques including breaking strength, changes in bed density under compaction and stress relaxation. The properties were determined using a specially constructed laboratory compaction simulator capable of reproducing compaction events typical of full scale production. It is shown that none of the conventional indices of compaction behaviour adequately predict the compaction properties of materials as described by their breaking strength: force profile. A phenomenon is described whereby the measurement of maximum force is not coincidental with the measurement of maximum punch penetration. Using model materials it is suggested that these differences are due to the visco elastic and plastic components of materials during compression. A new index - rise time - (the time between the initiation of compression and the point of maximum force application) is proposed as a useful means of predicting the behaviour of pharmaceutical solids during compression.
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612 |
Studies on drug molecules by theoretical methods, NMR and computer graphicsPooler, G. W. January 1986 (has links)
No description available.
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613 |
Cracking of laminated glass initiated by low velocity impactsCoward, David Paul January 2001 (has links)
No description available.
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614 |
Molecular studies of some excitatory neurotransmitters and a preliminary study of prostaglandin flexibilityDerricott, C. January 1983 (has links)
No description available.
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615 |
An experimental and computer study of a heat pump assisted solar energy heating systemGata, Z. S. January 1980 (has links)
No description available.
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616 |
Application of scattering models to optical surface inspectionObray, C. D. January 1983 (has links)
No description available.
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617 |
The kinetics of reaction epoxy powder coatingsProsser, J. L. January 1992 (has links)
No description available.
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618 |
Finite element methods for computational nonlinear opticsBuah, Patrick Asebiah January 1996 (has links)
No description available.
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619 |
Aspects of self stratifying coatingsBenjamin, Susan January 1994 (has links)
No description available.
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620 |
The economics of pharmaceutical research development : investment models, capital market imperfections and policy considerationsVernon, John A. January 2001 (has links)
No description available.
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