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Exposure to negative media messages related to LGBTQ+ issues have been associated with negative affect, depression, stress, and psychological distress among that population (e.g. Rotosky, Riggle, Horne, & Miller, 2009). Frost and Fingerhut (2016) have suggested that this exposure to negative media messages is a form of distal minority stress, which has been theorized to contribute to anticipated stigma or unfair treatment (Meyer, 2003). Thus, in the present study, we predicted that individuals who were exposed to more negative messages in the media will have more negative feelings about the election, report more anxiety and fear, and anticipate more discrimination due to their LGBT identity. Further, we hypothesized that negative feelings about the election would relate to more anxiety, fear, anticipated discrimination. However, because connection with the LGBTQ+ community and spiritual well-being have been associated with better mental health (Pflum et al., 2015; Greenfield et al., 2009), the current study explored whether community connection and spirituality relate to the other relations tested. Participants (N = 207) were recruited online through various social media platforms and participated in an online survey using Survey Monkey. The survey included the following measures: the Exposure to Negative Campaign Messages (adapted; Frost & Fingerhut, 2016), a self-created Presidential Election 2016 Response Questionnaire, Discrimination Scale (adapted; Kessler, Mickelson, and Williams, 1999), Connectedness to the LGBT Community Scale (Frost & Meyer, 2012), State-Trait Anxiety Form for Adults (Form Y1; Spielberg, Gorsuch, Lushene, Vagg, & Jacobs, 1977), Fear and Sense of Control Scale (Salcioglu, Urhan, Pirinccioglu, & Aydin, 2016), Spiritual Index of Well-Being Scale (Daaleman & Frey, 2004), Centrality Scale (Quinn, Williams, Quintana, Gaskins, & Pishori, 2014), and questions about frequently used social media sites. Results revealed, contrary to our hypotheses, that more negative messages in the media was not significantly related to negative feelings about the presidential election, r = .05, p = .524, or state-trait anxiety, r = .079, p = .341. In support of our hypotheses, negative feelings about the presidential election were significantly related to more anticipated discrimination in everyday life, r = .631, p < .001, state-trait anxiety, r = .577, p < .001, and fear, r = .663, p < .001. Exploratory analyses revealed that those with more negative feelings about the election felt less connected to the LGBTQ+ community, r = -.224, p = .001, and had a lower spiritual life schema, r = -.362, p < .001. Additional exploratory findings highlight the possibility that spiritual well-being may moderate the effect of being exposed to negative media messages and should be examined more specifically in the future. In sum, feelings resulting from media exposure may be more influential to mental health than media exposure itself.

Suicide is a leading cause of death in the United States. College students have increased exposure to suicidal ideation and deaths by suicide and may experience suicidal ideation as a means of escape from emotional pain or from severe psychopathology. There are a number of risk factors that are present which make a person more susceptible to dying by suicide. One of those risk factors is past exposure to suicide. The present study is an analysis of the exposure to suicide that is present on a college campus. This report includes an in-depth review of the literature on suicide exposure, the methodology of the current study, and descriptive statistics of the results and a discussion of the likelihood that an individual would intervene with a friend who may be suicidal. The report concludes with a discussion about the study findings, limitations of the research, and implications for future research.

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Indiana University-Purdue University Indianapolis (IUPUI) / The use of maternal urinary fluoride as a biomarker of prenatal fluoride exposure in epidemiology studies is increasing. However, the knowledge on maternal exposure to fluoride and its biomarkers, has not increased alongside. The objective of this dissertation was to improve our understanding of the dietary intake of fluoride (a major source of fluoride exposure), and spot urinary fluoride levels during pregnancy. Two secondary data analyses utilizing data from the Early Life Exposures in Mexico to ENvironmental Toxicants (ELEMENT) project were conducted, in a population of women living in a salt-fluoridated community. The first study estimated the dietary intake of fluoride over the course of pregnancy and assessed the influence of compliance with the dietary recommendations of intake of beneficial nutrients for pregnancy (calcium, iron, folate and protein) on the dietary intake of fluoride. The second study compared spot urinary fluoride in women during pregnancy and non-pregnancy (using one-year postpartum as a proxy for the non-pregnant state) and assessed associations between dietary factors (dietary fluoride intake, addition of table salt, calcium intake from diet and supplements, and dietary acid load) and urinary fluoride levels at each state. Results revealed that the median dietary intake of fluoride in pregnant women was 0.7 mg/day, increased with gestational age and in women who were moderately and highly compliant with recommendations of intake of beneficial nutrients for pregnancy. On the other hand, spot urinary fluoride levels during pregnancy did not significantly differ with those of women one-year postpartum, increased with gestational age, and decreased in calcium-supplemented women only during pregnancy. The dietary intake of fluoride, calcium, and dietary acid load were not associated with urinary fluoride in either state. Finally, reporting the addition of table salt to meals was associated with an increase in urinary fluoride only at one-year postpartum. The studies in this dissertation highlight the need for a deeper understanding of fluoride exposure and its biomarkers in the pregnant population. / 2022-07-01

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BACKGROUND AND OBJECTIVES: Research on in utero opioid exposure impacts has focused on Neonatal Opioid Withdrawal Syndrome (NOWS). However, possible impacts on fetal growth and newborn wellbeing have emerged, with inconsistencies likely driven by methodological issues. Our goal was to compare birth outcomes between newborns with prenatal opioid exposure and a matched control group. METHODS: Participants were identified manual review of electronic medical records of all deliveries over five years within a regional health system (6 delivery hospitals across 2 states). From over 18,000 births, 300 with prenatal opioid exposure and 300 control newborns matched on exposure, medical, and background factors were included. Additional factors were statistically controlled. Outcomes included pregnancy/delivery complications, newborn size, and newborn health complications. RESULTS: Compared to biochemically verified controls, exposed newborns had higher rates of fetal growth restriction, weighed less, had decreased length and head circumference, and had higher rates of respiratory distress, sepsis, and jaundice. No significant differences in gestational length, Apgar scores, or neonatal hypoglycemia were found. Adjusted regression analyses revealed that compared to controls, those exposed had an average 150 g decrease in birth weight, a two-fold increased risk for IUGR (OR = 2.09), a nearly three-fold (OR = 2.80) increased risk for jaundice, a more than seven-fold (OR = 7.40) increased risk for respiratory distress, and a thirty-fold (OR = 30.47) increased risk for sepsis. CONCLUSIONS: Results suggest significant pregnancy and newborn outcomes beyond NOWS following pregnancy opioid use, informing clinical screening and treatment decisions to enhance health and wellbeing in pregnancy, during the neonatal period, and beyond.

Background and objectives: Research on in utero opioid exposure impacts has focused on Neonatal Opioid Withdrawal Syndrome (NOWS). However, possible impacts on fetal growth and newborn wellbeing have emerged, with inconsistencies likely driven by methodological issues. Our goal was to compare birth outcomes between newborns with prenatal opioid exposure and a matched control group. Methods: Participants were identified via manual review of electronic medical records of all deliveries over five years within a regional health system (6 delivery hospitals across 2 states). From over 18,000 births, 300 with prenatal opioid exposure and 300 control newborns matched on exposure, medical, and background factors were included. Additional factors were statistically controlled. Outcomes included pregnancy/delivery complications, newborn size, and newborn health complications. Results: Compared to biochemically verified controls, exposed newborns had higher rates of fetal growth restriction, weighed less, had decreased length and head circumference, and had higher rates of respiratory distress, sepsis, and jaundice. No significant differences in gestational length, Apgar scores, or neonatal hypoglycemia were found. Adjusted regression analyses revealed that compared to controls, those exposed had an average 150 g decrease in birth weight, a two-fold increased risk for IUGR (OR = 2.09), a nearly three-fold (OR = 2.80) increased risk for jaundice, a more than seven-fold (OR = 7.40) increased risk for respiratory distress, and a thirty-fold (OR = 30.47) increased risk for sepsis. Conclusions: Results suggest significant pregnancy and newborn outcomes beyond NOWS following pregnancy opioid use, informing clinical screening and treatment decisions to enhance health and wellbeing in pregnancy, during the neonatal period, and beyond.