Weight loss maintenance and emotional and physical problems were investigated in subjects on a protein-sparing modified fast. Four months following a weight reduction program using the protein-sparing modified fast, twenty of the forty-two subjects were contacted. Each was asked to complete a questionnaire related to emotional and physical effects of the diet and a diet history checksheet. Each subject was weighed to determine if weight loss had been maintained. Results of the questionnaire, diet history, and blood chemistry analysis indicate that for these subjects, the modified fast may be safe and effective in reducing and maintaining weight loss over a short time period under close supervision by a physician.