Global ETD Search

1	Studies of functional interactions within yeast mediator and a proposed novel mechanism for regulation of gene expression / Hallberg, Magnus, January 2004 (has links) Diss. (sammanfattning) Umeå : Univ., 2004. / Härtill 4 uppsatser.
2	Yeast telomere structure : genetic analysis implicating a novel terminus-specific factor in telomeric silencing / Wiley, Emily A. January 1996 (has links) Thesis (Ph. D.)--University of Washington, 1996. / Vita. Includes bibliographical references (leaves [95]-102).
3	Gene-environment interaction in yeast gene expression / Smith, Erin N. January 2008 (has links) Thesis (Ph. D.)--University of Washington, 2008. / Vita. Includes bibliographical references (leaves 108-114).
4	DNA microarray approaches to understanding the regulation and evolution of gene expression networks Xue-Franzén, Yongtao, January 2009 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2009.
5	Evidence for the involvement of the zinc cluster protein Asg1p in the transcriptional regulation of some stress response genes in Saccharomyces cerevisiae Drolet, Jessica Ann. January 2007 (has links) Saccharomyces cerevisiae has developed mechanisms in order to survive harsh environmental conditions. This species responds to stresses such as ethanol, heat, and weak acid exposure via two well-characterized stress response pathways. These typically involve either the Hsf1p or the Msn2/4p transcriptional regulators. Recently, our lab has begun to characterize a member of the zinc cluster protein family: Asg1p (Activator of Stress Genes, systematic name: YIL130W), which is presumed to stimulate stress response genes independently of the Hsflp and Msn2/4p pathways. Previous work has revealed five target genes of Asg1p (HSP30, STP4, YER130C, TPO2, YRO2) thought to be involved in this novel stress response pathway. In this study, we attempted to better characterize the role of Asg1p and its target genes during stress induction. We first determined if the induction of certain Asg1p target genes by stress is strain specific. HSP30 induction by heat shock is specific to the W303 strain as shown by primer extension analysis. We then generated the deletion strains Deltaasg1 and Astp4 in W303. We observed a loss of induction of HSP30 in the Deltaasg1 deletion strain when cells were exposed to ethanol. This led us to believe that Asg1p does play a role in the stress response pathway. Also, we attempted to globally define the target sites of Asg1p in vivo on a genome-wide scale by combining Chromatin Immuno Precipitation with microarrays (ChIP-chip). We identified eight putative Asg1p target genes: YRO2, HSP78, ZRT2, ZRT1, MSN4, STP4, TPO2, and HSP30. Zinc -- metabolism. Zinc Fingers.
6	Structure and function of the yeast mediator tail domain / Béve, Jenny, January 2006 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2006. / Härtill 5 uppsatser.
7	Genome-wide patterns of histone modifications in fission yeast Sinha, Indranil, January 2010 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2010.
8	Isw2 complex slides nucleosomes to create repressive chromatin structure in vivo / Fazzio, Thomas G. January 2004 (has links) Thesis (Ph. D.)--University of Washington, 2004. / Vita. Includes bibliographical references (leaves 110-128).
9	Genome-wide patterns of histone modifications in fission yeast Sinha, Indranil, January 2010 (has links) Diss. (sammanfattning) Stockholm : Karolinska institutet, 2010.
10	Evidence for the involvement of the zinc cluster protein Asg1p in the transcriptional regulation of some stress response genes in Saccharomyces cerevisiae Drolet, Jessica Ann. January 2007 (has links) No description available. Zinc Fingers. Zinc -- metabolism.

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