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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
41

Synthèse chimioenzymatique d'analogues de l'acide glutamique potentiellement actifs dans le système nerveux central / Chemoenzymatic synthesis of analogs of glutamic acid potentially active in the central nervous system

Assaf, Zeinab 26 November 2010 (has links)
Pas de résumé disponible / Pas de résumé disponible
42

GAD 65 and its role in pancreatic tissue survival

Unknown Date (has links)
We employed three genotypes of GAD 65, wildtype (GAD 65 +/+), heterozygous (GAD 65 +/-) and knockout (GAD 65 -/-) to investigate the role of GAD 65 in survival of pancreatic islets. We analyzed the mRNA expression of pro-survival proteins including Bcl2 and Bax in pancreas of wildtype, heterozygous and knockout using Reverse Transcriptase Polymerase Chain Reaction (RTPCR). The level of expression of Bcl2 mRNA was down regulated in knockout mice pancreas and Bax to Bcl2 ratio was found higher in knockout mice pancreas suggesting higher cell death rate. However, further studies are required to recognize and understand the specific connections between apoptotic pathways and GAD 65 in pancreatic islets. / by Neeta Kumari. / Thesis (M.S.)--Florida Atlantic University, 2012. / Includes bibliography. / Electronic reproduction. Boca Raton, Fla., 2012. Mode of access: World Wide Web.
43

Group I and II metabotropic glutamate receptors are necessary for the activity-dependent maintenance of ribosomal integrity in chick auditory neurons

Nicholas, Alexander H. Hyson, Richard Lee. January 2004 (has links)
Thesis (M.S.)--Florida State University, 2004. / Advisor: Dr. Richard L. Hyson, Florida State University, College of Arts and Sciences, Dept. of Psychology. Title and description from dissertation home page (viewed 6/16/04). Includes bibliographical references.
44

Retinal ganglion cells vulnerability in a rat glaucoma model

Lau, Hoi-shan, Flora., 劉凱珊. January 2005 (has links)
published_or_final_version / Medical Sciences / Master / Master of Medical Sciences
45

Glutamatergic and GABAergic transmission regulate the maturation of vestibular circuitry for spatial recognition

Ng, Ka-pak., 吳嘉白. January 2010 (has links)
published_or_final_version / Physiology / Doctoral / Doctor of Philosophy
46

Immunocytochemical study of the developmental profile of glutamate receptor subunits in otolith neurons of the rat vestibular nucleus

羅凱恩, Law, Hoi-yan. January 2001 (has links)
published_or_final_version / Physiology / Master / Master of Philosophy
47

The role of growth factors and glutamate signalling in CNS myelination

Luzhynskaya, Aryna January 2012 (has links)
No description available.
48

The effects of guanidinium chloride, urea and sodium dodecyl sulfate on the endoproteinase Glu-C- catalyzed hydrolysis of N-t-BOC-L-glutamic acid-gas-phenyl ester

Delk, Roger Dale January 1994 (has links)
Endoproteinase Glu-C (EPGIu-C, EC 3.4.21.19), an enzyme isolated from the bacteria Staphylococcus aureus, has been found to cleave specifically at the carboxyl-terminal side of glutamyl and aspartyl peptide bonds. EPGIu-C has been reported to be stable and active in the presence of common denaturants such as guanidinium chloride, urea and sodium dodecyl sulfate (Drapeau, G.R. (1977) Methods in Enzymology, 47:189-191). In order assess the denaturant stability and activity of EPGIu-C, the effect of three common protein denaturants, guanidinium chloride, urea, and sodium dodecyl sulfate (SDS) on the proteolytic activity of EPGIu-C was studied.The kinetics of the hydrolyis reaction catalyzed by EPGIu-C was determined using the chromophoric substrate N-tBOC-L-glutamic acid-a-phenyl ester (BGPE).To compare theurea is significantly greater at the higher concentrations of urea. These results suggest that a complete cleavage of proteins substrate by EPGlu-C might occur more rapidly in 8.0 M urea than in 6.0 M GuCl, since EPGlu-C will be operating at a significantly higher catalytic efficiency in the urea solution. / Department of Chemistry
49

Autocrine/paracrine interactions modulating hormone release in the endocrine pancreas /

Cabrera, Over, January 2007 (has links)
Diss. (sammanfattning) Stockholm : Karolinska institutet, 2007. / Härtill 4 uppsatser.
50

The role of Hox cofactors in vertebrate spinal coed development

Rottkamp, Catherine Anne-Marie. January 2007 (has links)
Thesis (Ph. D.)--Case Western Reserve University, 2007. / [School of Medicine] Department of Neurosciences. Includes bibliographical references.

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