Thesis (Ph. D.)--University of Nevada, Reno, 2005. / "December, 2005." Includes bibliographical references (leaves 194-212). Online version available on the World Wide Web. Library also has microfilm. Ann Arbor, Mich. : ProQuest Information and Learning Company, [2005]. 1 microfilm reel ; 35 mm.

Epidemiological studies in humans have revealed a relationship between altered development in utero and an increased incidence of pathophysiology during postnatal life. One of the mechanisms underlying this relationship is thought to be exposure to excess glucocorticoids during critical phases of brain development. The aim of the current set of studies was to determine the effects of prenatal stress during discrete developmental windows on behaviour and endocrine function in male and female guinea pig offspring. Guinea pigs were used as the model for these studies as they are a long-gestation species that give birth to neuroanatomically mature young and fetal brain development is well characterized. Pregnant guinea pigs were exposed to a high frequency strobe light during the period of rapid fetal brain growth or the period of rapid brain myelination. Pregnant guinea pigs were allowed to deliver normally and guinea pig offspring were tested for ambulatory activity, anxiety and hypothalamic-pituitary-adrenal (HPA) axis function. Male offspring whose mothers were exposed to stress during the period of rapid brain growth exhibited increased anxiety behaviour, increased basal plasma cortisol levels and decreased plasma testosterone levels. We found that replacing testosterone in these animals reversed the behavioural and endocrine differences. Male offspring whose mothers were exposed to stress during the period of rapid myelination exhibited an increased plasma cortisol response to activation of the HPA axis. Female offspring whose mothers were exposed to stress during the period of rapid brain myelination exhibited decreased ambulatory activity and a blunted salivary cortisol response to the stress of the strobe light, but only during the estrous phase of the reproductive cycle. Therefore, the current set of studies has demonstrated the effects of prenatal stress on behaviour and HPA axis activity are dependent on; 1) the timing of the prenatal stress and 2) the hypothalamic-pituitary-gonadal axis in both male and female offspring. These studies have begun to uncover the mechanisms underlying programming and provide the basis for continuing research in humans.

Since the end of French colonial rule in Guinea, “independence” has held a central place in its political culture. Implying both dignity and self-determination for the sovereign people which possesses it, independence is a concept that has meaning only in relation to other nation-states and cultures. Yet the political elite that dominated Guinea’s First Republic constructed a new national culture around this concept. The Challenge of Guinean Independence, 1958-1971 examines Guinea’s assertion of its right to independence and the response of powerful Western players, especially the United States and France, as Guinea challenged their assumptions about the nature of African sovereignty. Considering the history of the international relations of a single African state that enjoyed limited international power and prestige challenges conventions in the historiography of both Africa and international relations. It illuminates and contextualizes expectations concerning the meaning of modernity, African sovereignty as a matter of international law, and the end of formal colonial rule coinciding with the tensions and competitions of the Cold War. The study demonstrates that the international context played a crucial role, both in conditioning the timing and form of decolonization and in shaping the international community’s adaptation of colonial patterns of economic and political interaction to the new reality of African nation-states. Focusing on the invention, development and reception of one country’s insistence on independence in turn illuminates significant issues and events: the end of French colonial rule; limitations on the sovereignty of non-European postcolonial states; the advent of neocolonialism and the failure of the nominally anti-colonial United States to oppose it; the ideological appeal of African unity as a means of safeguarding sovereignty and the compromises that its institutional form entailed; foreign aid and the notion that development for modernization could be stimulated from outside; and the implications of unlimited internal autonomy for a state’s people. Guinea’s independence ultimately challenged developing norms of Western economic and political interaction with new African states by complicating assumptions about the universality of Western notions of economic development, justice and morality.

This thesis investigates the efforts of the West Indian Church to establish and run a fascinating Mission in an area of West Africa already influenced by Islam or traditional religion. It focuses mainly on the Pongas Mission’s efforts to spread the Gospel but also discusses its missionary hierarchy during the formative years in the Pongas Country between 1855 and 1863, and the period between 1863 and 1873, when efforts were made to consolidate the Mission under black control and supervision. Between 1873 and 1900 when more Sierra Leonean assistants were hired, relations between them and African-descended West Indian missionaries, as well as between these missionaries and their Eurafrican host chiefs, deteriorated. More efforts were made to consolidate the Pongas Mission amidst greater financial difficulties and increased French influence and restrictive measures against it between 1860 and 1935. These followed an earlier prejudiced policy in the mission that was strongly influenced by the hierarchical nature of nineteenth-century Barbadian society, which was abandoned only after successive deaths and resignations of white superintendents and the demonstrated ability of black pastors to independently run the Mission. Instrumentalism aided the conversion process and the increased flow of converts threatened both the traditional belief systems and social order of the Pongas Country, resulting in confrontation between the Mission and traditional religion worshippers, while the lack of more legitimate trade in the Pongas Country and allegations of black missionaries’ illicit sexual relations and illegal trading caused the downfall of John Henry A. Duport, the Mission’s first black Head Missionary. In the late 1800s, efforts to establish a self-supporting, self-generating, and self-propagating church together with initiatives toward African agency in the Pongas Country failed. However, it was French activities and eventual consolidation of their interests in the Pongas Country from 1890 and their demand that Mission schools teach in French, together with successful recruiting of Mission students by the Roman Catholics and Muslim clerics in Guinea, that finally crippled it. Thus, by 1935 when the Gambia-Pongas Bishopric was established in the hope of rescuing the Mission, this gender-biased Christian enterprise in West Africa was already a spent force.

Esta tesis examina cómo las narrativas de María Nsué Angüe, Joaquín Mbomio Bacheng, Donato Ndongo-Bidyogo, y Juan Tomás Ávila Laurel re-escriben la historia de Guinea Ecuatorial. Los autores articulan un discurso contestatario a las construcciones sociales afincadas por el discurso homogéneo colonialista. Los análisis textuales se realizan tomando en cuenta la vigencia cultural española en el discurso político nacional inmediato a la independencia del país en 1968. Las obras cuestionan la definición de la identidad guineana con respecto a la implementación de los valores culturales, históricos, lingüísticos, religiosos, y políticos en el territorio guineano. Las indagaciones, los rechazos, las condenas, y las rupturas que se analizan las representaciones literarias son posibles mediante el acercamiento teórico de la memoria. A partir de esta interacción discursiva literaria surgen nuevas interpretaciones que permiten entender la experiencia histórica del sujeto guineano.

This thesis investigates the efforts of the West Indian Church to establish and run a fascinating Mission in an area of West Africa already influenced by Islam or traditional religion. It focuses mainly on the Pongas Mission’s efforts to spread the Gospel but also discusses its missionary hierarchy during the formative years in the Pongas Country between 1855 and 1863, and the period between 1863 and 1873, when efforts were made to consolidate the Mission under black control and supervision. Between 1873 and 1900 when more Sierra Leonean assistants were hired, relations between them and African-descended West Indian missionaries, as well as between these missionaries and their Eurafrican host chiefs, deteriorated. More efforts were made to consolidate the Pongas Mission amidst greater financial difficulties and increased French influence and restrictive measures against it between 1860 and 1935. These followed an earlier prejudiced policy in the mission that was strongly influenced by the hierarchical nature of nineteenth-century Barbadian society, which was abandoned only after successive deaths and resignations of white superintendents and the demonstrated ability of black pastors to independently run the Mission. Instrumentalism aided the conversion process and the increased flow of converts threatened both the traditional belief systems and social order of the Pongas Country, resulting in confrontation between the Mission and traditional religion worshippers, while the lack of more legitimate trade in the Pongas Country and allegations of black missionaries’ illicit sexual relations and illegal trading caused the downfall of John Henry A. Duport, the Mission’s first black Head Missionary. In the late 1800s, efforts to establish a self-supporting, self-generating, and self-propagating church together with initiatives toward African agency in the Pongas Country failed. However, it was French activities and eventual consolidation of their interests in the Pongas Country from 1890 and their demand that Mission schools teach in French, together with successful recruiting of Mission students by the Roman Catholics and Muslim clerics in Guinea, that finally crippled it. Thus, by 1935 when the Gambia-Pongas Bishopric was established in the hope of rescuing the Mission, this gender-biased Christian enterprise in West Africa was already a spent force.

Epidemiological studies in humans have revealed a relationship between altered development in utero and an increased incidence of pathophysiology during postnatal life. One of the mechanisms underlying this relationship is thought to be exposure to excess glucocorticoids during critical phases of brain development. The aim of the current set of studies was to determine the effects of prenatal stress during discrete developmental windows on behaviour and endocrine function in male and female guinea pig offspring. Guinea pigs were used as the model for these studies as they are a long-gestation species that give birth to neuroanatomically mature young and fetal brain development is well characterized. Pregnant guinea pigs were exposed to a high frequency strobe light during the period of rapid fetal brain growth or the period of rapid brain myelination. Pregnant guinea pigs were allowed to deliver normally and guinea pig offspring were tested for ambulatory activity, anxiety and hypothalamic-pituitary-adrenal (HPA) axis function. Male offspring whose mothers were exposed to stress during the period of rapid brain growth exhibited increased anxiety behaviour, increased basal plasma cortisol levels and decreased plasma testosterone levels. We found that replacing testosterone in these animals reversed the behavioural and endocrine differences. Male offspring whose mothers were exposed to stress during the period of rapid myelination exhibited an increased plasma cortisol response to activation of the HPA axis. Female offspring whose mothers were exposed to stress during the period of rapid brain myelination exhibited decreased ambulatory activity and a blunted salivary cortisol response to the stress of the strobe light, but only during the estrous phase of the reproductive cycle. Therefore, the current set of studies has demonstrated the effects of prenatal stress on behaviour and HPA axis activity are dependent on; 1) the timing of the prenatal stress and 2) the hypothalamic-pituitary-gonadal axis in both male and female offspring. These studies have begun to uncover the mechanisms underlying programming and provide the basis for continuing research in humans.

Since the end of French colonial rule in Guinea, “independence” has held a central place in its political culture. Implying both dignity and self-determination for the sovereign people which possesses it, independence is a concept that has meaning only in relation to other nation-states and cultures. Yet the political elite that dominated Guinea’s First Republic constructed a new national culture around this concept. The Challenge of Guinean Independence, 1958-1971 examines Guinea’s assertion of its right to independence and the response of powerful Western players, especially the United States and France, as Guinea challenged their assumptions about the nature of African sovereignty. Considering the history of the international relations of a single African state that enjoyed limited international power and prestige challenges conventions in the historiography of both Africa and international relations. It illuminates and contextualizes expectations concerning the meaning of modernity, African sovereignty as a matter of international law, and the end of formal colonial rule coinciding with the tensions and competitions of the Cold War. The study demonstrates that the international context played a crucial role, both in conditioning the timing and form of decolonization and in shaping the international community’s adaptation of colonial patterns of economic and political interaction to the new reality of African nation-states. Focusing on the invention, development and reception of one country’s insistence on independence in turn illuminates significant issues and events: the end of French colonial rule; limitations on the sovereignty of non-European postcolonial states; the advent of neocolonialism and the failure of the nominally anti-colonial United States to oppose it; the ideological appeal of African unity as a means of safeguarding sovereignty and the compromises that its institutional form entailed; foreign aid and the notion that development for modernization could be stimulated from outside; and the implications of unlimited internal autonomy for a state’s people. Guinea’s independence ultimately challenged developing norms of Western economic and political interaction with new African states by complicating assumptions about the universality of Western notions of economic development, justice and morality.

Esta tesis examina cómo las narrativas de María Nsué Angüe, Joaquín Mbomio Bacheng, Donato Ndongo-Bidyogo, y Juan Tomás Ávila Laurel re-escriben la historia de Guinea Ecuatorial. Los autores articulan un discurso contestatario a las construcciones sociales afincadas por el discurso homogéneo colonialista. Los análisis textuales se realizan tomando en cuenta la vigencia cultural española en el discurso político nacional inmediato a la independencia del país en 1968. Las obras cuestionan la definición de la identidad guineana con respecto a la implementación de los valores culturales, históricos, lingüísticos, religiosos, y políticos en el territorio guineano. Las indagaciones, los rechazos, las condenas, y las rupturas que se analizan las representaciones literarias son posibles mediante el acercamiento teórico de la memoria. A partir de esta interacción discursiva literaria surgen nuevas interpretaciones que permiten entender la experiencia histórica del sujeto guineano.

Med hjälp av tidigare forskning från västvärlden om lycka och kunskapen om vad tre guineaner finner värdefullt i vardagen kommer resonemang föras om vilka komponenter som kan vara viktigast i sökandet efter tillfredsställelse och lycka. Syftet är att identifiera dessa aspekter och tillföra något till den tidigare forskningen och att synliggöra hur de tre guineanernas syn på lycka kan vidga vårt (svenskarnas) perspektiv lycka. En kritisk jämförelse kommer göras mellan den tidigare forskningen och tolkningar av intervjuerna. För att undersöka området bör några frågeställningar besvaras: Vad prioriteras i vardagen, värdesätts som viktigast, för de tre  intervjuadeguineanerna? Hur är deras syn på lycka och tillfredsställelse? Vilka komponenter tycks för de intervjuade vara de viktigaste för eftersträvan avtillfredsställelse? Hur kan detta sättas i relation till västvärldens tidigare forskning och få en ny mening?