A review of the literature on homophobia indicates that negative attitudes toward homosexuals and homosexuality have been empirically related to numerous socio-demographic and attitudinal variables. Research to this date has focused on the relationship between individual variables and homophobia rather than examining multiple variables simultaneously. The purpose of the present investigation was to identify the factors which are predictive of homophobia. One hundred and ninety-four female and 115 male participants completed a biographical information questionnaire requesting socio-demographic information, self-proclaimed religiosity, frequency of church attendance, self-proclaimed political orientation, and political party identification. Participants also completed measures of attitudes toward male homosexuality, attitudes toward lesbianism, attitudes toward women, authoritarianism, sex anxiety, sexual attitudes, and socio-economic status. Statistical treatment of the data through principal components analysis indicated that homophobic attitudes are best predicted by a factor identified as "conservatism". Other factors were identified which predicted homophobia to a lesser extent. Male participant gender was determined to predict homophobia toward male homosexuals, but gender was not found to predict homophobic attitudes toward lesbians.