<p dir="ltr">Background. Although depression is a risk factor for cardiovascular disease (CVD), few clinical trials in people without CVD have examined the effect of depression treatment on CVD-related outcomes. It’s unknown if successful depression treatment improves indicators of CVD risk, such as CVD-relevant health behaviors, traditional CVD risk factors, and CVD events. </p><p dir="ltr">Methods. We examined data from eIMPACT trial, a phase II randomized controlled trial conducted from 2015-2020. Depressive symptoms, CVD-relevant health behaviors (self-reported CVD prevention medication adherence, sedentary behavior, and sleep quality) and traditional CVD risk factors (blood pressure and lipid fractions) were assessed. Incident CVD events over four years were identified using a statewide health information exchange. </p><p dir="ltr">Results. The intervention group exhibited greater improvement in depressive symptoms (p < 0.01) and sleep quality (p < 0.01) than the usual care group, but there was no intervention effect on systolic blood pressure (p = 0.36), low-density lipoprotein cholesterol (p = 0.38), high-density lipoprotein cholesterol (p = 0.79), triglycerides (p = 0.76), CVD prevention medication adherence (p = 0.64), or sedentary behavior (p = 0.57). There was an intervention effect on diastolic blood pressure that favored the usual care group (p = 0.02). CVD-relevant health behaviors did not mediate any intervention effects on traditional CVD risk factors. Twenty-two participants (10%) experienced an incident CVD event. The likelihood of an CVD event did not differ between the intervention group (12.1%) and the usual care group (8.3%; HR = 1.45, 95% CI: 0.62-3.40, p = 0.39). </p><p dir="ltr">Conclusions. Successful depression treatment alone improves self-reported sleep quality but is not sufficient to lower CVD risk of people with depression. Alternative approaches may be needed reduce CVD risk in depression. </p><p dir="ltr">Trial Registration: ClinicalTrials.gov Identifier: NCT02458690 </p><p dir="ltr">Keywords: depression, cardiovascular disease, blood pressure, lipids, medication adherence, sedentary behavior, sleep quality, collaborative care, internet interventions, clinical trial</p>

The aim of this qualitative study was to explore hospital-counselors view on collaboration in thedischarge-process from inpatient psychiatric care regarding individuals with comorbidity in form ofserious mental illness and substance abuse. Six hospital-counselors from different psychiatric in-patient wards in Stockholms county participated in the study. All participants had a degree in socialwork and five of them had earlier experience working in the municipality as social workers. Theresearch process was conducted using qualitative interviews, further applying a systemic view oncollaboration which consisted of three levels: structural-, organizational- and individual, which wasbased on the core concepts of integrated care and person-centered care. The results showed that thehospital-counselors acted as a “link” between the health care, municipality, and patient duringcollaboration. Collaboration itself was described as a process involving different actors andorganizations within the two main principal sectors. The complexity of the differences in economicinterests, view on support needs and responsibilities regarding treatment and further care seemed to becentral aspects influencing collaboration. Although the results largely confirm previous research, it hasbrought attention to specific claims on what facilitates collaboration and what undermines it.

Objectif principal: Il n’est pas démontré que les interventions visant à maîtriser voire modérer la médicamentation de patients atteints d’hypertension peuvent améliorer leur gestion de la maladie. Cette revue systématique propose d’évaluer les programmes de gestion contrôlée de la médicamentation pour l’hypertension, en s’appuyant sur la mesure de l’observance des traitements par les patients (CMGM). Design: Revue systématique. Sources de données: MEDLINE, EMBASE, CENTRAL, résumés de conférences internationales sur l’hypertension et bibliographies des articles pertinents. Méthodes: Des essais contrôlés randomisés (ECR) et des études observationnelles (EO) ont été évalués par 2 réviseurs indépendants. L’évaluation de la qualité (de ce matériel) a été réalisée avec l’aide de l’outil de Cochrane de mesure du risque de biais, et a été estimée selon une échelle à quatre niveaux de qualité Une synthèse narrative des données a été effectuée en raison de l'hétérogénéité importante des études. Résultats: 13 études (8 ECR, 5 EO) de 2150 patients hypertendus ont été prises en compte. Parmi elles, 5 études de CMGM avec l’utilisation de dispositifs électroniques comme seule intervention ont relevé une diminution de la tension artérielle (TA), qui pourrait cependant être expliquée par les biais de mesure. L’amélioration à court terme de la TA sous CMGM dans les interventions complexes a été révélée dans 4 études à qualité faible ou modérée. Dans 4 autres études sur les soins intégrés de qualité supérieure, il n'a pas été possible de distinguer l'impact de la composante CMGM, celle-ci pouvant être compromise par des traitements médicamenteux. L’ensemble des études semble par ailleurs montrer qu’un feed-back régulier au médecin traitant peut être un élément essentiel d’efficacité des traitements CMGM, et peut être facilement assuré par une infirmière ou un pharmacien, grâce à des outils de communication appropriés. Conclusions: Aucune preuve convaincante de l'efficacité des traitements CMGM comme technologie de la santé n’a été établie en raison de designs non-optimaux des études identifiées et des ualités méthodologiques insatisfaisantes de celles-ci. Les recherches futures devraient : suivre les normes de qualité approuvées et les recommandations cliniques actuelles pour le traitement de l'hypertension, inclure des groupes spécifiques de patients avec des problèmes d’attachement aux traitements, et considérer les résultats cliniques et économiques de l'organisation de soins ainsi que les observations rapportées par les patients. / Objective: Whether interventions including measurement and correction of patients’ attitude to antihypertensive medication can improve hypertension management is unclear. The review aims to determine the effectiveness of patient compliance measurement-guided medication management (CMGM) programs in essential hypertension. Design: Systematic review. Data sources: MEDLINE, EMBASE, CENTRAL, hypertension meetings abstracts, and bibliographies of identified articles. Methods: Randomized controlled trials (RCT) and observational studies (OS) were assessed by 2 reviewers independently. Quality assessment was performed with the Cochrane risk of bias tool and evaluated in a four-point continuum. A narrative data synthesis was performed due to significant heterogeneity among studies. Results: 13 studies (8 RCT, 5 OS) involving 2150 hypertensives were included. Five trials of CMGM with electronic devices as a sole intervention suggested decrease in blood pressure (BP) but the result may have been due to bias. Short-term BP improvement under CMGM in complex interventions was revealed in 4 studies of low-to-moderate quality. In 4 integrated care studies of higher quality the impact of CMGM component was not possible to distil and may be compromised by medication regimens. Regular feedback to the treating physician seems to be an essential component of CMGM and may be effectively mediated by a nurse or a pharmacist and via telecommunication. Conclusions: No convincing evidence for the effectiveness of CMGM as a health technology was found due to non-optimal study designs and methodological quality. Future research should follow accepted quality standards and current guidelines for the treatment of hypertension, include specific groups of patients with compliance problems and consider clinical, economic, patient-reported and organizational outcomes.

Objectif principal: Il n’est pas démontré que les interventions visant à maîtriser voire modérer la médicamentation de patients atteints d’hypertension peuvent améliorer leur gestion de la maladie. Cette revue systématique propose d’évaluer les programmes de gestion contrôlée de la médicamentation pour l’hypertension, en s’appuyant sur la mesure de l’observance des traitements par les patients (CMGM). Design: Revue systématique. Sources de données: MEDLINE, EMBASE, CENTRAL, résumés de conférences internationales sur l’hypertension et bibliographies des articles pertinents. Méthodes: Des essais contrôlés randomisés (ECR) et des études observationnelles (EO) ont été évalués par 2 réviseurs indépendants. L’évaluation de la qualité (de ce matériel) a été réalisée avec l’aide de l’outil de Cochrane de mesure du risque de biais, et a été estimée selon une échelle à quatre niveaux de qualité Une synthèse narrative des données a été effectuée en raison de l'hétérogénéité importante des études. Résultats: 13 études (8 ECR, 5 EO) de 2150 patients hypertendus ont été prises en compte. Parmi elles, 5 études de CMGM avec l’utilisation de dispositifs électroniques comme seule intervention ont relevé une diminution de la tension artérielle (TA), qui pourrait cependant être expliquée par les biais de mesure. L’amélioration à court terme de la TA sous CMGM dans les interventions complexes a été révélée dans 4 études à qualité faible ou modérée. Dans 4 autres études sur les soins intégrés de qualité supérieure, il n'a pas été possible de distinguer l'impact de la composante CMGM, celle-ci pouvant être compromise par des traitements médicamenteux. L’ensemble des études semble par ailleurs montrer qu’un feed-back régulier au médecin traitant peut être un élément essentiel d’efficacité des traitements CMGM, et peut être facilement assuré par une infirmière ou un pharmacien, grâce à des outils de communication appropriés. Conclusions: Aucune preuve convaincante de l'efficacité des traitements CMGM comme technologie de la santé n’a été établie en raison de designs non-optimaux des études identifiées et des ualités méthodologiques insatisfaisantes de celles-ci. Les recherches futures devraient : suivre les normes de qualité approuvées et les recommandations cliniques actuelles pour le traitement de l'hypertension, inclure des groupes spécifiques de patients avec des problèmes d’attachement aux traitements, et considérer les résultats cliniques et économiques de l'organisation de soins ainsi que les observations rapportées par les patients. / Objective: Whether interventions including measurement and correction of patients’ attitude to antihypertensive medication can improve hypertension management is unclear. The review aims to determine the effectiveness of patient compliance measurement-guided medication management (CMGM) programs in essential hypertension. Design: Systematic review. Data sources: MEDLINE, EMBASE, CENTRAL, hypertension meetings abstracts, and bibliographies of identified articles. Methods: Randomized controlled trials (RCT) and observational studies (OS) were assessed by 2 reviewers independently. Quality assessment was performed with the Cochrane risk of bias tool and evaluated in a four-point continuum. A narrative data synthesis was performed due to significant heterogeneity among studies. Results: 13 studies (8 RCT, 5 OS) involving 2150 hypertensives were included. Five trials of CMGM with electronic devices as a sole intervention suggested decrease in blood pressure (BP) but the result may have been due to bias. Short-term BP improvement under CMGM in complex interventions was revealed in 4 studies of low-to-moderate quality. In 4 integrated care studies of higher quality the impact of CMGM component was not possible to distil and may be compromised by medication regimens. Regular feedback to the treating physician seems to be an essential component of CMGM and may be effectively mediated by a nurse or a pharmacist and via telecommunication. Conclusions: No convincing evidence for the effectiveness of CMGM as a health technology was found due to non-optimal study designs and methodological quality. Future research should follow accepted quality standards and current guidelines for the treatment of hypertension, include specific groups of patients with compliance problems and consider clinical, economic, patient-reported and organizational outcomes.

No description available.

Background: Modern health systems are increasingly faced with the challenge to provide effective, affordable and accessible health care for people with chronic conditions. As evidence on the specific unmet needs and their impact on health outcomes is limited, practical research is needed to tailor chronic care to individual needs of patients with diabetes. Qualitative approaches to describe professional and informal caregiving will support understanding the complexity of chronic care. Results are intended to provide practical recommendations to be used for systematic implementation of sustainable chronic care models. Method: A mixed method study was conducted. A standardised survey (n = 92) of experts in chronic care using mail responses to open-ended questions was conducted to analyse existing chronic care programs focusing on effective, problematic and missing components. An expert workshop (n = 22) of professionals and scientists of a European funded research project MANAGE CARE was used to define a limited number of unmet needs and priorities of elderly patients with type 2 diabetes mellitus and comorbidities. This list was validated and ranked using a multilingual online survey (n = 650). Participants of the online survey included patients, health care professionals and other stakeholders from 56 countries. Results: The survey indicated that current care models need to be improved in terms of financial support, case management and the consideration of social care. The expert workshop identified 150 patient needs which were summarised in 13 needs dimensions. The online survey of these pre-defined dimensions revealed that financial issues, education of both patients and professionals, availability of services as well as health promotion are the most important unmet needs for both patients and professionals. Conclusion: The study uncovered competing demands which are not limited to medical conditions. The findings emphasise that future care models need to focus stronger on individual patient needs and promote their active involvement in co-design and implementation. Future research is needed to develop new chronic care models providing evidence-based and practical implications for the regional care setting.

Les personnes atteintes de troubles concomitants (TC) de santé mentale et d’usage de substances présentent des besoins biopsychosociaux particuliers et complexes, qui peuvent rendre leurs prises en charge plus ardue pour les professionnels de la santé. Au Canada comme dans d’autres pays, les infirmières et les infirmiers sont fréquemment appelés à intervenir auprès de personnes atteintes de TC par le biais d’une approche intégrée des soins centrés sur leurs besoins particuliers. Toutefois, les études soulignent des difficultés et barrières inhérentes à la complexité de cette prise en charge par les infirmières, comme le sentiment de fardeau ou d’échec professionnel, les attitudes défavorables ou l’inconfort à l’égard de ces personnes et le manque de connaissances ou d’habiletés quant à certaines approches psychothérapeutiques essentielles. Qui plus est, rares sont les occasions de formation continue portant spécifiquement sur les TC pour soutenir et mieux outiller les infirmières dans le développement de leurs compétences. Cette thèse par articles présente les résultats d’une étude visant à comprendre dans quelle mesure et de quelles manières un programme de formation continue virtuel portant sur les TC a contribué au développement des compétences des infirmières. Le programme de formation continue virtuel sur les TC développé et mis en place en 2018 au Centre hospitalier de l’Université de Montréal (CHUM) en s’appuyant sur le modèle Extension for Community Healthcare Outcomes (©ECHO), s’adresse à l’ensemble des professionnels de la santé et des services sociaux du Québec. Celui-ci constitue un modèle de formation continue visant à soutenir le développement des compétences de ces professionnels dans la prise en charge de conditions de santé chroniques et complexes. Le modèle ECHO repose sur trois théories sociales de l’apprentissage, incluant la Théorie sociale cognitive, la Théorie des communautés de pratique et la Théorie de l’apprentissage situé. Le programme ECHO sur les TC comprend des séances éducatives virtuelles offertes en continu, d’une durée de 90 minutes à chaque deux semaines, guidées par une équipe interprofessionnelle d’experts dans le domaine des TC. La participation au programme s’effectue par l’entremise de visioconférences simultanées, au cours desquelles les professionnels inscrits au programme sont invités à présenter une situation clinique vécue, laquelle faisant ensuite l’objet d’une riche discussion entre pairs et d’une rétroaction personnalisée par l’équipe d’experts. Des capsules didactiques portant sur les pratiques exemplaires dans le domaine des TC sont également présentées aux participants, en fonction de leurs besoins d’apprentissage. Un devis mixte convergent a été utiliser pour collecter et analyser les données QUANtitatives et QUALitatives issues d’une population potentielle de 65 infirmières ayant participé au programme de formation ECHO sur les TC pour les vagues de formation 2018-2019 et 2019-2020. Dans le volet QUAN, une étude de cohorte prospective observationnelle a été mené pour mesurer l’évolution des infirmières à six mois (T1) et 12 mois (T2) suivant leur entrée au programme (T0) quant à leur: 1) sentiment d’auto-efficacité; 2) participation; 3) satisfaction et acceptabilité; 4) connaissances; 5) attitude; et 6) perception de la performance clinique. Dans le volet QUAL, une étude descriptive interprétative a été réalisée auprès de 10 infirmières ayant participé au programme ECHO, afin d’explorer leur expérience et perceptions à l’égard du développement et de la mise en pratique de leurs compétences, ainsi que des facteurs ayant influencé ce processus. Enfin, l’emploi d’une stratégie de comparaison des résultats QUAN et QUAL a facilité leur intégration, permettant ainsi de mettre en évidence leurs similitudes, différences ou éléments de complémentarité. Les analyses de variance effectuées dans le volet QUAN de l’étude ont indiqué une amélioration significative quant au niveau de connaissances sur les TC (pT1–T0 = 0,0045; pT2–T0 = 0,0014) et au score d’attitude à l’égard des TC (pT1–T0 = 0,0472 ; pT2–T0 = 0,0139) des infirmières (n = 28) à T1 et T2. En contrepartie, seules les infirmières (n = 16/28) ayant participé à au moins 25 % des 20 séances virtuelles offertes au cours d’un curriculum de formation ont montré une augmentation significative de leur sentiment d’auto-efficacité à T2 (pT2–T0 = 0,0213). En complémentarité, l’analyse thématique réalisée dans le volet QUAL de l’étude a mis en lumière qu’au cours de leur participation, les infirmières ont davantage développé huit éléments de compétences propres à la pratique auprès de personnes atteintes de TC, et que plusieurs facteurs d’ordre personnel, interpersonnel, contextuel et organisationnel avaient facilité ou contraint ce processus. Enfin, les constats mixtes de l’étude, illustrés par six thèmes, font état de six conditions clés pour favoriser le développement des compétences et leur mise en œuvre dans la pratique: 1) des expériences de mise en pratique et de validation; 2) des relations de réciprocité et de confiance en contexte de formation interprofessionnelle; 3) un partage d’expériences similaires entre pairs et des activités de mentorat; 4) une collaboration avec des experts; 5) une attitude positive solidifiée à l’égard de l’exercice de son rôle professionnel en situation de complexité et d’adversité; et 6) des expériences d’apprentissage d’équipe, adaptées aux particularités des milieux et en partenariat avec les organisations. Cette étude a permis de mieux comprendre comment un programme de formation continue virtuel sur les TC reposant sur le modèle ECHO a contribué au développement des compétences des infirmières. Les résultats suggèrent que dans certaines conditions, le programme de formation ECHO sur les TC peut favorablement contribuer au développement des compétences des infirmières et au renouvellement de leur pratique. Des recommandations sont formulées à l’effet d’orienter la recherche vers l’évaluation des effets du modèle ECHO sur le changement des pratiques et la santé des personnes atteintes; et d’explorer des avenues de recherche visant la conjugaison de stratégies auprès des professionnels et sur le plan de l’intervention, du contexte et des organisations, pour favoriser la mise en œuvre effective des pratiques exemplaires. / People with concurrent disorders (CD) in mental health and substance use have specific and complex biopsychosocial needs, which can make their care more challenging for healthcare professionals. In Canada, as in other countries, nurses are frequently called upon to intervene with people with CD through an integrated approach to care that focuses on their specific needs. However, studies point to difficulties and barriers for nurses caused by the complexity of this care. These include feelings of being burdened or of professional failure, judgmental attitudes about or discomfort with these individuals, and lack of knowledge or skills in certain essential psychotherapeutic approaches. Moreover, there are few continuing education opportunities specifically focused on CD to support nurses and give them the tools they need to develop their skills. This article-based thesis presents the results of a study carried out to understand how, and to what extent, a virtual continuing education program on CD contributed to nurses’ competency development. The virtual continuing education program for CD was developed and implemented in 2018 at the Centre hospitalier de l’Université de Montréal (CHUM), based on the Extension for Community Healthcare Outcomes (©ECHO) model. It is intended for all health and social services professionals in Quebec. ECHO is a model of continuing education designed to support the competency development of these professionals in the management of chronic and complex health conditions. The ECHO model is based on three social theories of learning, including the Social Cognitive Theory, the Communities of Practice Theory, and the Situated Learning Theory. The ECHO program for CD consists of 90 minute virtual educational sessions, offered bi-weekly on an ongoing basis. The sessions are guided by an interprofessional team of experts in the field of CD. Participation in the program takes place through videoconferences, during which professionals enrolled in the program are invited to present a real-life clinical situation, which is then the subject of a rich peer discussion and personalized feedback from the team of experts. Short didactic presentations on best practices in the field of CD are also presented to participants, based on their learning needs. A convergent mixed-methods design was used to collect and analyze QUANtitative and QUALitative data from a potential population of 65 nurses who participated in the ECHO CD program during its first two cycle (2018–2019 and 2019–2020). In the QUAN component, a prospective observational cohort study was conducted to measure nurses’ evolution at six months (T1) and 12 months (T2) following their entry into the program (T0) with respect to their: 1) self-efficacy; 2) participation; 3) satisfaction and acceptability; 4) knowledge; 5) attitude; and 6) perceived clinical performance. In the QUAL component, an interpretive descriptive study was conducted with 10 nurses who had participated in the ECHO program. The study explored their experiences and perceptions regarding the development of their competency and their clinical practice, as well as factors that influenced this process. Finally, a strategy of comparing QUAN and QUAL results facilitated their integration and thus highlighted their similarities, differences, or complementary elements. Longitudinal analyses of variance performed in the QUAN component of the study indicated a significant increase in the level of knowledge about CD (pT1–T0 = 0.0045; pT2–T0 = 0.0014) and in the attitude score toward CD (pT1–T0 = 0.0472; pT2–T0 = 0.139) of nurses (n= 28) at T1 and T2. In contrast, only nurses (n = 16/28) who participated in at least 25% of the 20 virtual sessions offered during a program cycle showed a significant increase in their self-efficacy score at T2 (pT2–T0 = 0.0213). In addition, the thematic analysis conducted in the QUAL component of the study revealed that, during their period of participation, nurses further developed eight competency elements specific to practice with people with CD, and that several personal, interpersonal, contextual, and organizational factors either facilitated or constrained this process. Finally, the study’s mixed-methods findings, illustrated by six themes, point to six key conditions that foster the development of nurses’ competencies and their implementation in clinical practice: 1) Opportunities for practice and validation; 2) Reciprocal and trusting relationships in an interprofessional learning environment; 3) Peer-to-peer sharing of similar experiences and mentoring activities; 4) Collaboration with experts; 5) Reinforcement of positive attitudes about performing professional role in complex and adverse situations; and 6) Learning experiences that are team-based, tailored to the setting specifics and receive organizational support. This study provides a better understanding of how a virtual continuing education program for CD, based on the ECHO model, contributed to nurses’ competency development. The results suggest that under certain conditions, the ECHO program for CD can contribute positively to the development of nurses’ competencies and the renewal of their clinical practice. Recommendations are made in two areas: first, to direct research toward evaluating the impact of the ECHO model on practice change and health outcomes; and, second, to explore research avenues for combining strategies among professionals and with regard to intervention, context and organizations, to support effective implementation of best practices.

No description available.

Advances in medical technology have altered the need for certain types of surgery to be performed in traditional inpatient hospital settings. Less invasive surgical procedures allow a growing number of medical treatments to take place on an outpatient basis. Hospitals face growing competition from ambulatory surgery centers (ASCs). The competitive threats posed by ASCs are important, given that inpatient surgery has been the cornerstone of hospital services for over a century. Additional research is needed to understand how surgical volume shifts between and within acute care general hospitals (ACGHs) and ASCs. This study investigates how medical technology within the hospital industry is changing medical services delivery. The main purposes of this study are to (1) test Clayton M. Christensen’s theory of disruptive innovation in health care, and (2) examine the effects of disruptive innovation on appendectomy, cholecystectomy, and bariatric surgery (ACBS) utilization. Disruptive innovation theory contends that advanced technology combined with innovative business models—located outside of traditional product markets or delivery systems—will produce simplified, quality products and services at lower costs with broader accessibility. Consequently, new markets will emerge, and conventional industry leaders will experience a loss of market share to “non-traditional” new entrants into the marketplace. The underlying assumption of this work is that ASCs (innovative business models) have adopted laparoscopy (innovative technology) and their unification has initiated disruptive innovation within the hospital industry. The disruptive effects have spawned shifts in surgical volumes from open to laparoscopic procedures, from inpatient to ambulatory settings, and from hospitals to ASCs. The research hypothesizes that: (1) there will be larger increases in the percentage of laparoscopic ACBS performed than open ACBS procedures; (2) ambulatory ACBS will experience larger percent increases than inpatient ACBS procedures; and (3) ASCs will experience larger percent increases than ACGHs. The study tracks the utilization of open, laparoscopic, inpatient and ambulatory ACBS. The research questions that guide the inquiry are: 1. How has ACBS utilization changed over this time? 2. Do ACGHs and ASCs differ in the utilization of ACBS? 3. How do states differ in the utilization of ACBS? 4. Do study findings support disruptive innovation theory in the hospital industry? The quantitative study employs a panel design using hospital discharge data from 2004 and 2009. The unit of analysis is the facility. The sampling frame is comprised of ACGHs and ASCs in Florida and Wisconsin. The study employs exploratory and confirmatory data analysis. This work finds that disruptive innovation theory is an effective model for assessing the hospital industry. The model provides a useful framework for analyzing the interplay between ACGHs and ASCs. While study findings did not support the stated hypotheses, the impact of government interventions into the competitive marketplace supports the claims of disruptive innovation theory. Regulations that intervened in the hospital industry facilitated interactions between ASCs and ACGHs, reducing the number of ASCs performing ACBS and altering the trajectory of ACBS volume by shifting surgeries from ASCs to ACGHs.