The thesis is concerning rotator assembly at Indexator. A need to increase production has been seen and it can be done by implementing an optimized assembly process. In addition to the assembly process a new design on workstations and new test equipment is needed.The study resulted into three assembly process proposals. The processes were balanced, layouts were produced and Plant simulation was utilized to produce simulation models. Each proposal were analyzed based on cost, performance, ease of implementation, flexibility and worker condition. This resulted in a stationary assembly process being most promising and a 3D simulation model was produced for visualization and better understanding. The stationary assembly process has a capacity for 90 rotators per day, while reducing the amount of workers by one.The layout of the workstations was done based on the assembly process layout and further developed to make the work cell lean and ergonomic. It resulted in three workstations to perform the assembly. The test bench was developed by creating target specifications, establish a test procedure and decide components for the test bench layout. The finished test bench can measure dynamic torque, count particles to ensure cleanliness and is able to run the test unattended. / Examensarbetet handlar om montering av rotatorer på Indexator. Målet är att ta fram en optimerad monteringsprocess som kan implementeras i Indexators fabrik utan svårigheter. Den nya monteringsprocessen kommer kräva en ny design på arbetsstationerna och nya testbänkar.Fyra koncept på monteringsprocessen togs fram, baserat på monteringens behov och målsättning. Efter utvärdering så modifierades de fyra koncepten till tre förslag på monteringsprocesser. Processerna balancerades, layouter utvecklades och simuleringsmodeller producerades för varje process. Varje förslag analyserades baserat på kostnad, prestanda, implementation,flexibilitet och arbetar-förhållande. Resultatet blev en stationär monteringsprocess och en 3Dsimulering gjordes för visualisering och förståelse. Den stationära monteringsprocessen har en kapacitet på 90 rotatorer per dag och reducerar behovet av montörer.Layouten för monteringsstationerna baseras på processens layout och har modifierats för ergonomiska aspekter. Inom monteringsstationerna så utvecklades layouten för att minimera antalet onödiga rörelser för montören. Testriggens design utvecklades genom att analysera de behov som fanns, skapa en kravspecifikation samt utvärdera och besluta om testprocedur, upplägg för testrigg och dess ingående komponenter. Testriggen uppfyller målsättningen som är att kunna mäta dynamiskt vridmoment, räkna partiklar för att säkerställa renhet i rotatorn och kunna utföra testningen självgående för att frigöra montören under testprogrammet.

Orientador: Carol Hollingworth Collins / Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Química / Made available in DSpace on 2018-08-22T07:24:16Z (GMT). No. of bitstreams: 1 Silva_CarlaGrazieliAzevedoda_D.pdf: 4489958 bytes, checksum: f1c0299f6db7beed410c437dcdfc5886 (MD5) Previous issue date: 2013 / Resumo: Este trabalho apresenta o desenvolvimento de fases estacionárias (FE) para cromatografia líquida de alta eficiência em fase reversa (CLAE-FR) e cromatografia com fluido supercrítico (CFS) a partir da imobilização térmica de poli(metiloctadecilsiloxano) (PMODS) sobre suportes de sílicas metalizadas com zircônio e titânio. O processo de imobilização térmica do PMODS foi otimizado aplicando-se planejamento composto central. O polímero, os suportes e as fases estacionárias foram caracterizados por testes físicoquímicos e cromatográficos. As fases estacionárias Si(PMODS), Si-Zr(PMODS) e Si-Ti(PMODS) apresentaram os melhores resultados quando foi aplicada a temperatura de 120 °C por 16 horas. As melhores FE foram submetidas ao processo de capeamento. Estas FE mostraram eficiências entre 82.000 e 90.000 pratos m e boas separações com picos simétricos para compostos apolares e picos com simetria adequada, segundo parâmetros estabelecidos pela Farmacopéia Americana (United States Pharmacopeia), para compostos polares, avaliados pelos testes de Engelhardt, Tanaka, Neue, SRM 870 e pelo modelo dos parâmetros de solvatação utilizando CFS. A presença do óxido metálico no suporte resultou em FE com maior estabilidade química em condições drásticas de fase móvel (pH 1,7 e pH 10 a 50 °C), quando comparada com fases similares baseadas em sílica nua. A reação de capeamento melhorou a estabilidade química das FE e diminuiu o número de silanóis residuais. As FE Si-Zr(PMODS), Si-Ti(PMODS), Si-Zr(PMODS)ec e Si- Ti(PMODS)ec apresentam potencialidade na separação de fármacos psicoativos, filtros ultravioleta (UV), xantinas e hidrocarbonetos policíclicos aromáticos (HPA), utilizando CLAE e CFS. / Abstract: This work presents the development of stationary phases (SP) for high performance liquid chromatography in the reversed phase (RP-HPLC) and for supercritical fluid chromatography (SFC) prepared by the sorption and thermal immobilization of poly(methyloctadecylsiloxane) (PMODS) onto silica and metalized silica supports modified with zirconium and titanium. The immobilization process was optimized using central composite design for determination of the best conditions of time and temperature. The polymer, supports and stationary phases were characterized with physico-chemical and chromatographic tests. The stationary phases Si(PMODS), Si-Zr(PMODS) and Si-Ti(PMODS) presented the best results when a temperature of 120 °C for 16 hours was applied. The best SP were submitted to endcapping processes. These SP showed efficiencies between 82,000 and 90,000 plates m and good separations with symmetric peaks for apolar and polar compounds evaluated by the Engelhardt, Tanaka, Neue and SRM 870 tests and the solvation parameter model using supercritical fluid chromatography (SFC). The presence of metallic oxide on the supports resulted in stationary phases with better chemical stability under drastic conditions of mobile phase (pH 1.7 and pH 10 at 50 °C), when compared to similar stationary phases based on bare silica. The endcapping reaction improved the chemical stability. The SP Si-Zr(PMODS), Si- Ti(PMODS), Si-Zr(PMODS)ec e Si-Ti(PMODS)ec presented potentialities for the separation different pharmaceutical compounds used as psychotropic drugs, ultraviolet (UV) filters, xanthines, and polycyclic aromatic hydrocarbons (PAH), using separations in HPLC and SFC. / Doutorado / Quimica Analitica / Doutor em Ciências

Master thesis presents overview of existing types of check valves, their features, uses and issue called "cracking". Experimental part of this thesis focuses on the lift and swing check valves. Results of the measurement are evaluated from non-stationary flow point of view by developing and analyzing static and dynamic characteristics. This thesis takes into account losses and dynamic effects as main viewpoints. Two methods for measuring non-stationary velocities are used. Direct method called Gibson and indirect method laser doppler anemometry. Goal of the master thesis is to increase understanding of the check valves and their applicability.

This master´s thesis describes the design and realization of the simulation in program Tecnomatix Process Simulate. The thesis deals with the creation of a simulated assembly line of gluing a protective glass to the headlight. For this operation is using four stationary robotic arms. Created simulation behaves like a real robotic assembly line. In simulation is implemented several input sensors, robotic operations and conveyer structure. The control is done with PLC programmed, designed in TIA portal 14. Thesis includes a detailed description of the design whole simulation, together with the Tecnomatix Process Simulate environment. This software offer a many external commissioning and three bigger were tested, two kinds of OPC servers and PLCSIM Advanced. The conclusion of the diploma thesis describes the way of simulation control with visualization of whole process cell.

[pt] As fluorquinolonas constituem uma importante classe de agentes antimicrobianos sintéticos utilizados clinicamente por mais de 30 anos. Além da atividade antibacteriana, algumas fluorquinolonas, assim como seus complexos metálicos, mostraram ter atividade citotóxica, sendo, portanto, promissores como agentes antitumorais. Neste trabalho, obtivemos complexos de Au(III), Cu(II) e Bi(III) com as seguintes fluorquinolonas: norfloxacina, levofloxacina e esparfloxacina. Esses novos complexos foram caracterizados por diversas técnicas, tais como: análise elementar, condutimetria, espectroscopia na região do infravermelho, ressonância paramagnética eletrônica (RPE), ressonância magnética nuclear (RMN) de 1H e 13C, espectroscopia UV-Vis, fluorescência estacionária e resolvida no tempo. Atividades biológicas foram realizadas para todos os complexos. Usualmente, as fluorquinolonas coordenam-se aos íons metálicos de modo bidentado, através da carbonila do ácido carboxílico e da carbonila cetônica. Esta coordenação foi confirmada para os complexos de Cu(II), entretanto, para os complexos de Au(III) e Bi(III), os resultados de infravermelho e do RMN de 1H e 13C mostraram que a coordenação foi feita através dos nitrogênios do anel piperazina, uma coordenação não encontrada usualmente para as fluorquinolonas. Os complexos de Au(III) mostraram ser ativos frente às linhagens tumorais A20 (Linfoma murino), B16-F10 (Melanoma murino) e K562 (Leucemia mielóide humana). Os complexos de Cu(II) mostraram significativa atividade antiparasitária, enquanto os complexos de Bi(III), mostraram atividade antibacteriana. / [en] The fluoroquinolones are an important class of synthetic antimicrobial agents clinically used for over 30 years. In addition to antibacterial activity, some fluoroquinolones, as well as their metal complexes, presented cytotoxic activity and are therefore promising as antitumor agents. In order to obtain new complexes of Au (III) and other metal ions that have biological activity, this work had the objective to synthesize new complexes using ligands of the group of fluoroquinolones. These new complexes were characterized by various techniques such as elemental analysis, conductometry, infrared spectroscopy, electron paramagnetic resonance (EPR), nuclear magnetic resonance (NMR) of 1H and 13C NMR, UV-Vis, stead state and time-resolved fluorimetry studies. Biological activities were analized for all complexes. Usually, the fluoroquinolones coordinate to the metal ions as bidentate through the carbonyl and carboxylic acid ketonic carbonyl group. This was confirmed Cu(II) complex, however, for Au(III) and Bi (III) complexes, the results of IR and 1H and 13C NMR showed that the coordination was trough the nitrogen using the piperazine ring, a coordination not usually found for fluoroquinolones. The complexes of Au(III) shown to be active against the A20 tumor cell lines (murine lymphoma), B16-F10 (murine melanoma) and K562 (human myeloid leukemia). Complexes of Cu(II) showed significant antiparasitic activity, whereas complexes of Bi(III) have shown antibacterial activity.

Under the framework of this PhD project, a study on chromatographic behaviour of selected azaarenes on octadecylsilica stationary phases during their separation by reversed phase liquid chromatography was developed. The main goal was aimed at an application of the basic RPLC principles on the retention behaviour of azaarenes including the effects such as peak tailing, peak broadening, irreproducible retention or strong retention on a stationary phase. This study was particularly focused on basic azaarenes, also called acridines, which belong to a group of persistent organic pollutants providing mutagenic and/or carcinogenic activity. The retention patterns were studied on a group of eight acridines that are often present in environmental samples polluted with polycyclic aromatic compounds. The mixture of acridines was separated under isocratic elution conditions on three octadecylsilica stationary phases using two different binary mixtures as a mobile phase. Evaluation of the surface properties of the selected stationary phases was firstly performed, followed by the separation experiments. The structure of the experiments was designed to evaluate the effect of three different factors on the retention behaviour of acridines: properties of a stationary phase, composition of a mobile phase and physical-chemical properties of acridines. The treatment of the results was based on the capacity factor values providing the best fitting and repeatability of data, but other parameters that evaluate thermodynamic and kinetic aspects of the separation process were also given. Simple correlations between the three factors and a character of retention mechanism of acridines on the given separation system were found. Application of this knowledge simplifies an optimisation process and helps to solve common separation problems for acridines, but also for other basic analytes displaying similar physical-chemical properties (Mr and pKa).

The topic of this master's thesis is the time lapse from stationary camera images. Unwanted phenomena, which arise in time lapse, were analyzed and algorithms to overcome these limitations were designed. The algorithms were implemented and compared using the captured dataset. The resulting application creates time lapse from the video input and allows users to choose the processing technique including the setting of appropriate parameters.

Dissertation thesis is a 5-publications' collection concerning characterization and application potential of cyclodextrins, polysaccharides and macrocyclic antibiotics based chiral stationary phases. The effects of stationary phase and mobile phase are studied. This approach ensures the complex insight into separation systems studied. Systems with different nature of chiral selector were studied by HPLC. Namely, macrocyclic antibiotics and derivatized polysaccharides were used for experiments. Former ones provided better results for enantioseparation of non-coded amino acids than latter ones. Dynamic coating procedure was used for preparation of a new chiral stationary phase. Characterization of new cationic cyclodextrin based chiral stationary phase was performed. Linear free energy relationship method was used for characterization of two different separation systems, i.e. newly prepared stationary phase and commercially available stationary phase. Based on results obtained, newly prepared stationary phase showed better results for separation of different achiral groups of analysts. New stationary phase prepared by dynamic coating was compared with chromatographic system, in which the chiral selector was used as a mobile phase additive. The chiral selector used for the two different approaches was...

Målet med detta projekt var att utforma ett tidsrapporteringssystem åt Online CC AB för att effektivisera deras kunders tidsrapportering. Systemet är en webbapplikation som ska användas till att rapportera in tid som framdeles kan exporteras till valfritt lönesystem för lönehante-ring av personal. Detta system är grunden för ett framtida, fulländat system som har utökad funktionalitet. Produkten togs fram med Ex-treme Programming samt testdriven utveckling. Under utvecklingen jobbade utvecklingsgruppen med välkända och beprövade metoder för att säkerställa ett system av hög kvalité. Webbapplikationen nyttjar moderna teknologier och ramverk för webbutveckling – inklusive Microsofts ASP.NET MVC 4 och Entity Framework. Det visade sig att apputveckling är ett diffust område där de senaste verktygen inom verksamhetsgrenen inte förhållandevis förenklade arbetet. Ett system som fungerar såväl på mobila enheter, i form av en hybridapplikation, som stationära enheter, som webbapplikation, krävde att utvecklings-gruppen var erfarna inom respektive områden. I slutet av projektet var inte alla ställda krav uppfyllda - men eftersom vi använder oss av testdriven utveckling så är systemet fullt operationsdugligt. De krav som implementerades, gjordes det till fullo. Till sist så kan det visa sig att de senaste teknologierna och ramverken inte alltid är de bästa att nyttja. Mer beprövade metoder och teknologier kan i vissa fall vara mer lämpliga. / The goal of this project was to design a timesheet system for Online CC AB in order to make time reporting more efficient for their customers. The system is a web application that is to be used for time reporting in-which, later on can be exported to a salary system of their choice for salary transactions of personnel. This system is the foundation for a future, all-in-one system with extended functionality. The product was produced using Extreme Programming and Test-Driven Development. During development the development team worked with well-renowned and well-tried methods to ensure a system with the utmost quality. The web application utilizes modern technologies and frame-works for web development – including Microsoft’s ASP.NET MVC 4 and Entity Framework. It’s shown that app development is a diffuse field in which the latest tools within the field do not comparatively simplify the work. A system that works on as-well as mobile units, in the form of a hybrid application, as stationary units, in the form of a web application, demands the development team to be experienced within respective fields. At the end of the project not all requirements are met – however due to us using Test-Driven Development, the system is fully operational. Those requirements that were implemented are done so fully. Furthermore, it’s shown that the latest technologies and frame-works not always are best-suited for usage. More well-tried methods and technologies can in some cases be more appropriate

Der stationäre Einzelhandel ist eine Domäne, die sowohl unter der digitalen Transformation als auch unter dem Einfluss der COVID-19-Pandemie leidet. Besonders das Wachstum des E-Commerce und die Möglichkeit des mobilen Einkaufs über Smart Devices schaffen neue Herausforderungen (Fulgoni, 2015; Reinartz et al., 2019). Dabei zeigen sich eine rückläufige Kund:innenfrequenz und stagnierende Umsätze als Folge eines veränderten Kund:innenverhaltens (Handelsverband Deutschland, 2019, 2020). Diese Situation macht es für den stationären Einzelhandel unerlässlich innovative Services zu gestalten, um den neuen Anforderungen gerecht zu werden (Doherty & Ellis-Chadwick, 2010; Fulgoni, 2015; Geiger et al., 2021; Reinartz et al., 2019). Eine vielversprechende Herangehensweise kann es sein, an dem Alleinstellungsmerkmal des stationären Einzelhandels, der Serviceinteraktion (Interaktion zwischen Servicepersonal und Kund:innen), anzusetzen und diese zu stärken. Emotionen sind im Servicekontext hochrelevant und machen einen wichtigen Teil der Serviceerfahrung aus (Bagozzi et al., 1999; Burns & Neisner, 2006). Insbesondere die Fähigkeit des Servicepersonals, die Emotionen der Kund:innen zu verstehen und darauf zu reagieren, ist erfolgsentscheidend für Serviceinteraktionen (Bahadur et al., 2018; Bitner et al., 1994; Mattila & Enz, 2002). ... Im Rahmen dieses Betrags adressieren wir folgende Forschungsfrage: Wie kann eine digital gestützte und emotionsbasierte Interaktion zwischen Kund:innen und Servicepersonal wertvoll gestaltet werden? Methodisch orientiert sich der Beitrag an dem Design Science Research (DSR) Paradigma (Hevner et al., 2004; Vaishnavi et al., 2015). Zunächst werden der theoretische Hintergrund zur Relevanz von Emotionen in Serviceinteraktionen und der Wert von Interaktionen vermittelt. Danach wird in zwei Designzyklen die Entwicklung und Evaluation eines IT-Artefakts und eines Interaktionsartefakts vorgestellt. Dabei werden insbesondere die Auswirkungen der Interaktion hinsichtlich ihres Einflusses auf die emotionale Situation der Kund:innen und den resultierenden Value in Interaction untersucht. [Aus: Einleitung]