Kan, Wai Chi. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2010. / Includes bibliographical references (p. 111-116). / Abstract --- p.i / Acknowledgement --- p.iii / List of Publications --- p.vi / List of Figures --- p.xi / List of Tables --- p.xii / Chapter 1 --- Introduction --- p.1 / Chapter 1.1 --- Terahertz Radiation --- p.1 / Chapter 1.2 --- Biomedical Applications of Terahertz Imaging --- p.3 / Chapter 1.3 --- THz Spectroscopy --- p.4 / Chapter 1.4 --- Osteoarthritis --- p.4 / Chapter 1.5 --- Aim and motivation --- p.5 / Chapter 1.6 --- Overview of thesis --- p.5 / Chapter 2 --- Theory --- p.7 / Chapter 2.1 --- Propagation of electromagnetic field through dielectric media --- p.7 / Chapter 2.2 --- Deconvolution --- p.10 / Chapter 2.3 --- Baseline offset --- p.12 / Chapter 2.4 --- Frequency-dependent Refractive Index and Absorption Coefficient --- p.15 / Chapter 2.4.1 --- Reflection Geometry --- p.15 / Chapter 2.4.2 --- Transmission Geometry --- p.17 / Chapter 2.5 --- Conversion of Optical Delay into Depth --- p.22 / Chapter 2.6 --- Finite Difference Time Domain Method --- p.23 / Chapter 2.7 --- Summary --- p.25 / Chapter 3 --- Terahertz Systems --- p.26 / Chapter 3.1 --- Terahertz Pulsed Generation --- p.26 / Chapter 3.2 --- Terahertz Pulsed Detection --- p.28 / Chapter 3.3 --- Terahertz Pulsed Imaging (TPI) System --- p.29 / Chapter 3.4 --- Reflection System --- p.29 / Chapter 3.4.1 --- Flatbed System --- p.29 / Chapter 3.4.2 --- Probe --- p.32 / Chapter 3.5 --- Transmission System --- p.36 / Chapter 3.5.1 --- Antenna --- p.39 / Chapter 3.6 --- Data Acquisition --- p.40 / Chapter 3.6.1 --- Flatbed System --- p.40 / Chapter 3.6.2 --- Probe --- p.42 / Chapter 3.7 --- Baseline Validation --- p.46 / Chapter 4 --- Osteoarthritis --- p.48 / Chapter 4.1 --- Introduction --- p.48 / Chapter 4.2 --- Cartilage Composition and Structure --- p.49 / Chapter 4.3 --- 〇A symptoms --- p.51 / Chapter 4.4 --- Other Imaging Techniques --- p.52 / Chapter 4.5 --- Sample Preparation and Histology --- p.54 / Chapter 5 --- THz Pulsed Imaging of OA --- p.58 / Chapter 5.1 --- Results --- p.58 / Chapter 5.1.1 --- Optical Delays --- p.59 / Chapter 5.1.2 --- Estimation of surface refractive index --- p.69 / Chapter 5.1.3 --- Conversion of Optical Delay into Cartilage Thickness --- p.72 / Chapter 5.1.4 --- Correlation with Histology --- p.74 / Chapter 5.1.5 --- Errors and Problems --- p.80 / Chapter 5.2 --- FDTD of cartilage layers --- p.85 / Chapter 5.3 --- Conclusion --- p.87 / Chapter 6 --- Sliced Cartilage Sample and Bone Measurement --- p.88 / Chapter 6.1 --- Sliced Cartilage Samples --- p.88 / Chapter 6.1.1 --- Multi-reflections of sliced cartilage samples --- p.89 / Chapter 6.1.2 --- The influence of pressure on cartilage thickness --- p.91 / Chapter 6.1.3 --- Estimation of surface refractive index of sliced cartilage samples --- p.93 / Chapter 6.1.4 --- Comparison between sliced cartilage and knee joint measurements --- p.95 / Chapter 6.2 --- Bone --- p.97 / Chapter 7 --- Transmission System Result --- p.99 / Chapter 7.1 --- Data Validation --- p.99 / Chapter 7.1.1 --- Water spectrum --- p.99 / Chapter 7.1.2 --- Quartz measurement --- p.100 / Chapter 7.2 --- Liquid cell --- p.100 / Chapter 7.3 --- Cartilage Transmission Result --- p.103 / Chapter 7.4 --- Difficulties and problems --- p.105 / Chapter 7.5 --- Conclusions --- p.106 / Chapter 8 --- Conclusions and future work --- p.107 / Chapter 8.1 --- Summary --- p.107 / Chapter 8.2 --- Discussion --- p.107 / Chapter 8.3 --- Suggestions for further study --- p.109 / Bibliography --- p.111