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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Non-drug prevention of osteoporosis a thesis submitted in partial fulfillment ... for the degree of Master of Science, Geriatric Nursing ... /

Kao, Li. January 1997 (has links)
Thesis (M.S.)--University of Michigan, 1997. / Includes bibliographical references.
2

Non-drug prevention of osteoporosis a thesis submitted in partial fulfillment ... for the degree of Master of Science, Geriatric Nursing ... /

Kao, Li. January 1997 (has links)
Thesis (M.S.)--University of Michigan, 1997. / Includes bibliographical references.
3

Survey of Saudi Arabian physicians observed use by postmenopausal females of nutrition, lifestyle changes and medication prescriptions for osteoporosis prevention and treatment /

Jamal-Allial, Aziza Abudlah, January 2004 (has links)
Thesis (M.S.)--University of Missouri-Columbia, 2004. / "Master of Science in Nutritional Science with minor in Statistics"--T.p. Typescript. Vita. Includes bibliographical references (leaves 127-146). Also available on the Internet.
4

Survey of Saudi Arabian physicians observed use by postmenopausal females of nutrition, lifestyle changes and medication prescriptions for osteoporosis prevention and treatment

Jamal-Allial, Aziza Abudlah, January 2004 (has links)
Thesis (M.S.)--University of Missouri-Columbia, 2004. / "Master of Science in Nutritional Science with minor in Statistics"--T.p. Typescript. Vita. Includes bibliographical references (leaves 127-146). Also available on the Internet.
5

Therapeutic potential of nucleic acid aptamers against sclerostin in the treatment of osteoporosis

Lyu, Quanxia 21 August 2017 (has links)
Osteoporosis is a skeletal disease characterized with poor bone quality and low bone mineral density. The pathogenesis of osteoporosis is the imbalance of bone resorption and bone formation. Two strategies can be employed to cure osteoporosis. One is to inhibit bone resorption and the other is to stimulate bone formation. Currently, therapeutic drugs approved by FDA are mainly antiresorptive agents. Till now, there is only one bone anabolic agent approved. Obviously, more efforts should be poured into the development of bone anabolic agents. Sclerostin is a key negative regulator of osteoblast Wnt signaling making it a promising therapeutic target for bone anabolic therapy. Anti-sclerostin humanized monoclonal antibody romosozumab, which could effectively promote bone formation, has been accepted by the FDA for the review of biologic license application in 2017. However, there are several concerns about the humanized anti-sclerostin antibody, including immunogenicity, high cost of production and relative low stability. Nucleic acid aptamers are short single stranded oligonucleotides. They can bind to their targets with similar high affinity as antibodies. Moreover, aptamers have some superior advantages compared to antibodies, such as no immunogenicity, easily synthesized, and high stability. Aptamers against sclerostin could be a promising alternative to antibodies in terms of promotion of bone formation and reversal of osteoporosis. In this thesis, 20 rounds of SELEX were performed to select aptamers with high binding affinity and specificity to sclerostin. The inhibition potency of aptamer candidates to the antagonistic effect of sclerostin on Wnt signaling was also evaluated. Low KD and EC50 values of aptamer candidates against sclerostin implied a great potential of sclerostin aptamer being novel agents to promote bone formation. The study establishes the foundation for the next stage of preclinical studies and it will benefit the development of novel bone anabolic agents to reverse osteoporosis.
6

Bone metabolism in men /

Gillberg, Peter, January 2001 (has links)
Diss. (sammanfattning) Uppsala : Univ., 2001. / Härtill 5 uppsatser.
7

Comparison of texture classification methods to evaluate spongy bone texture in osteoporosis /

Bidesi, Anup Singh. January 2004 (has links)
Thesis (M.S.)--University of Missouri-Columbia, 2004. / Typescript. Includes bibliographical references (leaves 80-85). Also available on the Internet.
8

Determinants of peak bone mass in young adult women

Zagarins, Sofija E., January 2009 (has links)
Thesis (Ph. D.)--University of Massachusetts Amherst, 2009. / Includes bibliographical references (p. 169-191). Print copy also available.
9

Comparison of texture classification methods to evaluate spongy bone texture in osteoporosis

Bidesi, Anup Singh. January 2004 (has links)
Thesis (M.S.)--University of Missouri-Columbia, 2004. / Typescript. Includes bibliographical references (leaves 80-85). Also available on the Internet.
10

Risk factors for osteoporosis among Caucasian, Filipina, and Mexican American women /

Morton, Deborah J. January 1900 (has links)
Thesis (Ph. D.)--University of California, San Diego, and San Diego State University, 1999. / Includes bibliographical references (leaves 142-162).

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