Thesis (M. Eng. Sc.)--University of Adelaide, Dept. of Electrical and Electronic Engineering, 1994? / Includes bibliographical references (leaves 91-93).

Thesis (M.S.)--University of Wisconsin--Madison, 1982. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaf 23).

Thesis (Ph. D.)--University of Wisconsin--Madison, 1981. / Typescript. Vita. Description based on print version record. Includes bibliographical references (leaves 258-267).

Master of Science / Department of Computer Science / Daniel A. Andresen / With an improvement in technology and miniaturization of sensors, there have been attempts to utilize the new technology in various areas to improve the quality of human life. One main area of research that has seen an adoption of the technology is the healthcare sector. The people in need of healthcare services find it very expensive this is particularly true in developing countries. As a result, this project is an attempt to solve a healthcare problem currently society is facing. The main objective of the project was to design a remote healthcare system. It’s comprised of three main parts. The first part being, detection of patient’s vitals using sensors, second for sending data to cloud storage and the last part was providing the detected data for remote viewing. Remote viewing of the data enables a doctor or guardian to monitor a patient’s health progress away from hospital premises. The Internet of Things (IoT) concepts have been widely used to interconnect the available medical resources and offer smart, reliable, and effective healthcare service to the patients. Health monitoring for active and assisted living is one of the paradigms that can use the IoT advantages to improve the patient’s lifestyle. In this project, I have presented an IoT architecture customized for healthcare applications. The aim of the project was to come up with a Remote Health Monitoring System that can be made with locally available sensors with a view to making it affordable if it were to be mass produced. Hence the proposed architecture collects the sensor data through Arduino microcontroller and relays it to the cloud where it is processed and analyzed for remote viewing. Feedback actions based on the analyzed data can be sent back to the doctor or guardian through Email and/or SMS alerts in case of any emergencies.

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Recent guidelines recommend oxygen saturation (SpO(2)) levels of 90%-95% for preterm neonates on supplemental oxygen but it is difficult to discern such levels with current pulse oximetry sonifications. We tested (1) whether adding levels of tremolo to a conventional log-linear pulse oximetry sonification would improve identification of SpO(2) ranges, and (2) whether adding a beacon reference tone to conventional pulse oximetry confuses listeners about the direction of change. Participants using the Tremolo (94%) or Beacon (81%) sonifications identified SpO(2) range significantly more accurately than participants using the LogLinear sonification (52%). The Beaton sonification did not confuse participants about direction of change. The Tremolo sonification may have advantages over the Beacon sonification for monitoring SpO(2) of preterm neonates, but both must be further tested with clinicians in clinically representative scenarios, and with different levels of ambient noise and distractions. Crown Copyright (C) 2016 Published by Elsevier Ltd. All rights reserved.

published_or_final_version / Orthopaedic Surgery / Doctoral / Doctor of Philosophy

The use of optical methods for performing non-invasive physiological and biochemical monitoring has been investigated, with particular emphasis on the application of near-infrared spectrophotocetry for following changes in the redox state of cytochrome oxidase. Initial studies of the gross optical properties of in vivo tissue were made using an image intensifier. These demonstrated that some light is transmitted through biological tissues and that such material is very highly scattering. In order to investigate the feasibiity of non-invasively monitoring changes in the redox state of cytochrome oxidase in vivo. spectrophotometric and oxygen measurements were made on solutions containing the pure enzyme and yeast cell suspensions. These demonstrated the high affinity that the enzyme has for oxygen in such preparations, in contrast to the much lower apparent affinities in vivo that have been reported. These results were then modelled mathematically, and a possible-explanation for this anomaly suggested. Potential problems with applying this method are also presented. The interest in cytochrome oxidase is due to its importance in oxidative metabolism. However in performing this role it also assists in the prevention of oxidative damage, whose contribution to various disease states in paediatrics is briefly considered. Two instruments were also constructed, and used, firstly to measure the spectral characteristics of transmitted and reflected light in vivo. ana secondly to study the cardiac synchronous pulsatile component of this light (commonly referred to as the photoplethysmogram).

Failure to recognize and respond to changes in a patient’s condition is a limitation in the effective utilization of Medical Emergency Teams (METs). A system that uses smartphone technology to facilitate vital signs collection at bedside has been developed. The alerts engine, based upon Mount Sinai Hospital’s (MSH) MET calling criteria, can automatically alert the MET of patients exhibiting abnormal vital signs. The system, without automated alerting, was piloted at MSH. Sensitivity and specificity calculations revealed that the MSH algorithm had a lower sensitivity and specificity than the Cuthbertson or the Modified Early Warning Score algorithms. This suggests that the MSH algorithm, compared to the others, was poor at identifying patients that did and did not require a MET consultation. Furthermore, the low positive predictive value suggests that the majority of alerts were not associated with a MET call. Therefore, the MSH algorithm is not recommended for the automated system.