Die gegenwärtigen Möglichkeiten der 3D-Computergrafik, insbesondere der Visualisierung und interaktiven Manipulation virtueller Welten, sind schon länger ins Blickfeld geraten. Eine, dem menschlichen Wahrnehmungsvermögen angepasste Technik, verbessert und erleichtert dabei das Verstehen komplexer mehrdimensionaler Strukturen wesentlich. Diese Arbeit zeigt einen Weg der Realisierung eines 3D-Stadtmodells als neuartiges Werkzeug für die Stadtplanung auf, welches einerseits neue Methoden des interaktiven Stadtplanens einräumt und andererseits interessante Perspektiven für den menschlichen Sinn aufzeigt. Zunächst sind stadtplanerische und computergrafische Grundlagen erläutert und daraus Anforderungen an ein virtuelles Stadtmodell abgeleitet. Anschließend werden einige im Kontext stehende Arbeiten betrachtet. Der Schwerpunkt der Arbeit beschäftigt sich mit der Aufstellung einer Methodik für die semiautomatische Erstellung eines dreidimensionalen Stadtszenarios zum Zwecke der virtuellen Stadtplanung. Hierfür werden diverse bestehende Daten- und Informationsbestände analysiert und hinsichtlich ihrer Eignung für die Erstellung eines 3D-Stadtmodells bewertet. Im Weiteren werden diesbezüglich angewandte Datenbeispiele und Visualisierungsergebnisse vorgestellt. Besonderer Wert wird insgesamt auf die Fortführung bzw. die Wiederverwendbarkeit des 3D-Stadtmodells gelegt, um spätere Ergänzungen von größeren Bestandteilen zu gewährleisten. Zum Schluss wird das Ergebnis bewertet und daraus erwachsene forschungsrelevante Ausblicke aufgezeigt.

A new district is going to be built in the center of Västerås. The area is an old industrial area and the buildings in this area are considered as an cultural heritage environment. When Västerås Stad is planning for development in the central parts of Västerås there are a number of rules to adhere to. For example, Västerås Stad wants the new buildings to incorporate the existing buildings. They want, that an, urban environment is created and that buildings that are already built is telling a story and that history should be preserved. The design program, authored by the City of Västerås and the other stakeholders, has in Kopparlunden Syd, created a clear change in functions and buildings. The district has a clear vision of the relationship between the residents and the city's desired functions. The construction of a vibrant urban environment should be seen as fulfilled. This essay will look how Västerås Stads guidelines for cultural heritage is used in this new district and it will also look at how the design plan for the area will work.Kopparlunden Syd is the first stage of three developments and in case the other two stages follow the same line, Västerås, will receive a much-needed addition of a district with several functions as well as an architectural mix between old and new. If the design program is taking care of other interests is more questionable. The cultural heritage risks being lost among all the new buildings and functions for relaxation and leisure activities are minimal. The district has a tendency to become a transport route through or to once home. It is clear that rules are built in if you look at the design program when it comes to the functions of the buildings. Relationship between the cultural heritage and the vision is fulfilled when it comes to rules to relate to. But the cultural heritage is more than just rules to be followed. The legacy is history. The heritage should be highlight and that the district should not distort the cultural heritage environment.

Die systemische Verabreichung von Amoxizillin/Metronidazol (AM) als Zusatz zu Scaling/Root planing (SRP) in der Behandlung der generalisierten Aggressiven Parodontitis (gAP) führt zu guten klinischen und mikrobiologischen Ergebnissen. Die lokale antiseptische Zusatzmedikation mit Chlorhexidin in einem Controlled-Delivery-Device (PerioChip, PC) verbessert das Ergebnis von SRP in der Behandlung der Chronischen Parodontitis. Die Anwendung in der Behandlung der gAP ist bisher noch nicht untersucht worden. Ziele: Der Effekt von PC als Zusatz zu SRP in der Therapie der gAP wurde untersucht. Die Wirksamkeit wurde mit der Standardmedikation AM verglichen. Neben klinischen Parametern wurde die Konzentration des Entzündungsmarkers Calprotectin in der Sulkusflüssigkeit (SF) bestimmt. Material/Methode: 36 gAP-Patienten (18/Gruppe, 35+/-4 Jahre) wurden mit SRP und randomisiert entweder mit AM oder PC behandelt. Zur Baseline, 3 und 6 Monate nach SRP wurden die klinischen Parameter PD, CAL, BoP, Pus erhoben sowie SF-Proben tiefer und flacher Referenzstellen entnommen. Die Calprotectin-Konzentration in der SF wurde mittels ELISA bestimmt. Ergebnisse: 3 Monate nach SRP zeigten beide Gruppen signifikante Verbesserungen der klinischen Parameter, wobei noch keine Unterschiede zwischen den Gruppen bestanden. Während die AM-Gruppe stabil blieb, verschlechterten sich mehrwurzelige Zähne und tiefe Referenzstellen der PC-Gruppe wieder signifikant. Nach 6 Monaten wies die AM-Gruppe signifikant mehr CAL-Gewinn und PD-Reduktion auf. Pus war nur noch in der PC-Gruppe nachweisbar. Die Calprotectin-Konzentration war zwar in beiden Gruppen signifikant gesunken, Unterschiede zwischen den Gruppen bestanden jedoch aufgrund hoher Standardabweichungen nicht. Schlussfolgerung: AM zeigte eine bessere klinische Wirksamkeit und Langzeitstabilität als PC. Aufgrund großer interindividueller Variabilität spiegelte die SF-Konzentration von Calprotectin die klinischen Unterschiede nicht wider. / Adjunctive systemic administration of amoxicillin/metronidazole (AM) in generalized aggressive periodontitis (gAP) therapy results in good clinical and microbiological outcome. Adjunctive use of chlorhexidine within a controlled-delivery-device (PerioChip, PC) improves the outcome of scaling/root planing (SRP) in chronic periodontitis therapy. Its effect in the treatment of gAP has not been evaluated. Aims: The effect of adjunctive use of PC in the treatment of gAP was investigated. Efficacy of PC was compared to the standard treatment with AM. Clinical parameters and the concentration of the inflammation marker calprotectin within gingival crevice fluid (GCF) were measured. Material/methods: 36 gAP patients (18/group, 35+/-4 years) were treated by SRP either AM or PC. Clinical parameters PD, CAL, BoP and Pus were recorded at baseline, 3 and 6 months after therapy. GCF was sampled at deep and shallow reference sites and the concentration of calprotectin was measured by ELISA. Results: Both groups showed significant improvements of clinical parameters 3 months after SRP, however differences between groups were not significant. While the AM-group remained clinically stable, multirooted teeth and deep reference sites of the PC-group showed significant deterioration again. 6 months after SRP, the AM-group showed significant more CAL gain and PD reduction. Pus was detectable in the PC group only. The concentration of calprotectin in GCF had significantly decreased in both groups; however differences between groups were not significant due to high standard deviations. Conclusion: AM showed higher efficacy in terms of clinical treatment outcome and long-term stability than PC. Due to high interindividual variability, GCF-concentrations of calprotectin failed to reflect clinical differences.

Background: Hitherto no study has been published on the effect of the adjunctive administration of essential oils following scaling and root planing (SRP). This study describes the effect of a mouthrinse consisting of essential oils (Cymbopogon flexuosus, Thymus zygis and Rosmarinus officinalis) following SRP by clinical and microbiological variables in patients with generalized moderate chronic periodontitis. Methods: Forty-six patients (aged 40–65 years) with moderate chronic periodontitis were randomized in a double-blind study and rinsed their oral cavity following SRP with an essential oil mouthrinse (n = 23) or placebo (n = 23) for 14 days. Probing depth (PD), attachment level (AL), bleeding on probing (BOP) and modified sulcus bleeding index (SBI) were recorded at baseline and after 3 and 6 months. Subgingival plaque was taken for assessment of major bacteria associated with periodontitis. Results: AL, PD, BOP and SBI were significantly improved in both groups after three (p < 0.001) and 6 months (p ≤ 0.015). AL improved significantly better in the test than in the control group after 3 and 6 months (p < 0.001), so did PD after three months in the tendency (p = 0.1). BOP improved better in the test group after 3 months (p = 0.065). Numbers of Treponema denticola (p = 0.044) and Fusobacterium nucleatum (p = 0.029) decreased more in the test than in the control group after 3 months, those of Tannerella forsythia after 6 months (p = 0.039). Prevotella micra (p < 0.001,p = 0.035) and Campylobacter rectus (p = 0.002,p = 0.012) decreased significantly in both groups after 3 months. Conclusions: The adjunctive use of a mouthrinse containing essential oils following SRP has a positive effect on clinical variables and on bacterial levels in the subgingival biofilm.

Abstract OBJECTIVES: The objective of the present study is to compare the effect of systemic adjunctive use of azithromycin with amoxicillin/metronidazole to scaling and root planing (SRP) in a clinical study. MATERIALS AND METHODS: Data from 60 individuals with chronic periodontitis were evaluated after full-mouth SRP. Antibiotics were given from the first day of SRP, in the test group (n = 29), azithromycin for 3 days and, in the control group (n = 31), amoxicillin/metronidazole for7 days. Probing depth (PD), attachment level (AL), and bleeding on probing (BOP) were recorded at baseline and after 3 and 12 months. Gingival crevicular fluid was analyzed for matrix metalloprotease (MMP)-8 and interleukin (IL)-1beta levels. Subgingival plaque was taken for assessment of the major bacteria associated with periodontitis. RESULTS: In both groups, PD, AL, and BOP were significantly reduced (p < 0.001). A few significant differences between the groups were found; AL and BOP were significantly better in the test than in the control group at the end of the study (p = 0.020 and 0.009). Periodontopathogens were reduced most in the test group. CONCLUSIONS: A noninferiority of the treatment with azithromycin in comparison with amoxicillin/metronidazole can be stated. The administration of azithromycin could be an alternative to the use of amoxicillin/metronidazole adjunctive to SRP in patients with moderate or severe chronic periodontitis; however, a randomized placebo-controlled multicenter study is needed. CLINICAL RELEVANCE: Application of azithromycin as a single antibiotic for 3 days might be considered as an additional adjunctive antibiotic to SRP in selected patients.

Balance between matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) is required for normal wound healing. Chronic inflammation, such as that seen in cardiovascular and periodontal diseases, may upset this balance. The aim of this study was to determine whether initial periodontal therapy would have an effect systemically on the levels of MMP-9 and TIMP-1. Twenty-one patients with generalized chronic periodontitis were enrolled in the study. Clinical examinations were conducted and parameters measured. Scaling and root planing was performed and blood analysis done to determine the plasma concentrations of MMP-9 and serum concentrations of TIMP-1. Initial periodontal therapy resulted in improvements in gingival inflammation and plaque levels. No effect on the plasma concentrations of MMP-9 and serum concentrations of TIMP-1 could be found following therapy.

Avec la mondialisation, le Maghreb a connu, ces dernières années, de nombreux bouleversements dans les grandes villes. Les médinas et centres anciens ne sont plus au centre des débats comparativement aux morceaux de villes internationales, réalisés par des mécanismes d'investissement ou de partenariat entre les gouvernements maghrébins et les investisseurs originaires des pays arabes du Golfe Persique.Ces nouveaux projets urbains, localisés principalement dans les sites offrant un grand potentiel touristique –tel les fronts d'eau- témoignent d'une part, de l'ampleur des opérations, de leurs implications, et d'autre part, indiquent des changements profonds qui interrogent le chercheur dans de multiples directions : sociale, économique, architecturale, urbanistique...En effet, et en dépit du fait que les avantages de ce genre d'opérations sont multiples, la projection au sein des capitales maghrébines d'une architecture de haut-standing importée des pays émiratis, donne naissance à ce que les spécialistes de l'urbain appellent «des greffes urbaines» qui marquent profondément les espaces urbains concernés.La présente recherche tente de cerner les différentes dynamiques urbaines, nées de l'ouverture des territoires urbains maghrébins à l'investissement étranger et d'étudier le passage des façons de faire la ville dites locales, à une nouvelle fabrique de la ville, importée d'ailleurs. Il s'agit de mesurer les impacts sur la ville-hôte et son système de gestion et d'interroger les changements introduits du point de vue social et économique tout en l'inscrivant dans les politiques de développement durable. / Since the opening of the Maghreb to the world, many changes were recorded in large cities. Many big urban projects, whose realization is provided by investors from Arab countries of the Persian Gulf and located in sites with great potential like waterfronts, are carried out like in international cities.Those projects demonstrate the originality of the operations, their implications and indicate profound changes.Despite the fact that the benefits of such operations are manifold, the projection of architecture imported from Persian Golf countries in the capitals of the Maghreb, give rise to what town planners call "urban transplants".This research will identify the different urban dynamics, born after the opening of the territories and especially strategic sites of the region to foreign investment.In a nutshell, this research identifies the impacts of projects on the city and its management system, and examine changes relative to the concept of sustainable development.

La ville africaine est marquée par un dualisme du modèle urbain. A côté de la ville moderne, administrée, équipée, " légale ", se développent les quartiers " illégaux ", sans équipements ni services urbains de base. La Côte d'Ivoire n'échappe pas à cette situation. Au lendemain des indépendances, elle entreprend la plus vaste opération de géographie volontaire en vue de réduire les injustices spatiales et les inégalités entre régions du Sud forestier ; « l'opération San-Pedro ». Objectif: mettre en valeur une région jusqu'alors totalement enclavée et en marge du « miracle économique ivoirien » ; le Sud-ouest du pays avec comme point d'ancrage, la création d'un port en eau profonde et d'une ville nouvelle. Malgré un projet d'urbanisme largement concerté, San-Pedro abrite aujourd'hui l'un des plus grands quartiers précaires de l'Afrique de l'ouest, favorisant ainsi une fragmentation de plus en plus accentuée de la ville. On observe aujourd'hui dans la ville, moins de 10% des occupations immobilières ayant faits l'objet d'un enregistrement cadastral et d'un droit foncier réel inattaquable. Ce faible pourcentage illustre l'échec du système de l'immatriculation foncière, seule voie légale de sécurisation foncière et immobilière. Cela pose la question fondamentale d'autres voies alternatives à la sécurisation foncière et immobilière. D'où le nécessaire développement des systèmes d'adressage qui, à l'absence de cadastre général, permet de localiser les parcelles à partir de l'espace public afin d'améliorer la connaissance du patrimoine immobilier c'est-à-dire assurer une identification publique des biens et des droits existants facilitant ainsi leur sécurisation et leur reconnaissance juridique ultérieure. A cet effet, de nombreux pays africains ont lancé ces dernières années, des opérations d'adressage visant à servir d'alternative au cadastre fiscal et aux projets difficiles et lents de « régularisation foncière » en promouvant des formes simplifiées et principalement littérales d'identification des parcelles.Cette thèse vise donc à établir à San-Pedro, l'intérêt de l'utilisation d'un système d'adressage dans les politiques de sécurisation foncière et immobilière. Elle cherche à comprendre les relations entre l'adressage et le "droit à la ville", c'est-à-dire le droit d'accès aux ressources urbaines notamment d'accès à la propriété et à la sécurité du logement. Pour appréhender ces relations, il s'avère nécessaire d'entreprendre l'analyse sous l'angle de la justice spatiale tout en soulignant l'importance de l'adressage comme outil de reconnaissance des droits fonciers locaux et surtout d'intégration sociale et économique des populations.Cette approche ouvre de nouvelles perspectives méthodologiques à exploiter dans la réforme des systèmes fonciers et cadastraux des pays africains. / The African city is marked by a dualism of urban model. Alongside the modern city, administered equipped "legal" grow "illegal" areas, no equipment or basic urban services. Côte d'Ivoire is no exception to this. After independence, she undertook the largest operation of voluntary geography to reduce spatial injustices and inequalities between regions of southern forest; "Operation San Pedro." Objective: To develop a region until completely enclosed and outside the "Ivorian economic miracle", the South-west of the country with as an anchor, creating a deep water port and a new city . Despite a largely collaborative project planning, San Pedro now houses one of the largest shantytowns of West Africa, thereby promoting fragmentation increasingly accentuated the city. We observe today in the city, less than 10% of real estate occupations having made the subject of a land registration and real property of an indefeasible right. This low percentage shows the failure of the system of land registration, the only legal way of land and property security. This raises the fundamental question of alternative ways to land and property security. Where necessary the development of addressing systems, the lack of general survey, used to locate plots from public space to improve the knowledge of the real estate that is to say, ensure public identification of property and existing rights and facilitating their security and their subsequent legal recognition. To this end, many African countries have launched in recent years, addressing operations to serve as an alternative to fiscal cadastre and slow and difficult projects "land regularization" promoting simplified forms and mostly literal identification plots.Therefore this thesis aims to establish in San Pedro, the interest of the use of an addressing system in the policies of land and property security. It seeks to understand the relationship between the address and the "right to the city", that is to say, the right of access to urban resources including homeownership and housing security. To understand these relationships, it is necessary to undertake an analysis in terms of spatial justice while emphasizing the importance of addressing as a tool for recognition of local land rights, especially social and economic integration populations.This approach opens new methodological perspectives to operate in the reform of land tenure and cadastral African

A ênfase em se abordar um tema de tese cujas reflexões e análises se pautam na relação entre o homem e o espaço nas áreas centrais, tendo a 'rua' como referência, reflete uma preocupação, enquanto estudioso do espaço urbano, de um problema cada vez maior em nossas cidades, a perda gradativa dos espaços públicos de circulação para a convivência, os encontros e a recreação. Essa problemática urbana vem se acirrando há várias décadas, em função da depreciação acelerada desses ambientes ditos 'comuns a todos', acompanhada da respectiva perda de sua função, ou inversão de funções, em consequência do processo de 'esvaziamento do homem público' e do correspondente alargamento da esfera privada no meio urbano, acarretando um incentivo à busca cada vez mais acentuada de espaços privados de consumo, lazer, cultura, práticas esportivas, como também respaldando o significativo avanço da iniciativa privada nas (re)adequações das formas espaciais públicas e sua respectiva 'gestão'. Esta pesquisa teve como objetivo avaliar as condições de uso atual do espaço público da rua nas áreas centrais, identificando as variáveis que acarretaram e acarretam sua depreciação acelerada e sua respectiva perda de função, para que se possam propor formas adequadas de aproveitamento e destinação desse espaço a toda a população. Observou-se que não há uma preocupação real em se criarem políticas públicas que possibilitem uma readequação dos espaços públicos nas áreas centrais, devolvendo-os a todos os cidadãos indistintamente, pois elas esbarram em prioridades que resguardam os valores dos grupos sociais de renda média e alta. Faz-se necessário, dessa forma, recompor os espaços destinados ao pedestre. Os órgãos públicos responsáveis pelo planejamento e gerenciamento de tráfego, como também pelo planejamento urbano, juntamente com a comunidade e pesquisadores de diversas áreas de conhecimento, devem criar um fórum de debate onde possam estabelecer novas formas de intervenções no espaço urbano, de modo que os aspectos técnicos, sociais, econômicos e culturais se integrem de forma a repensar a cidade a curto, médio e longo prazo. Nota-se, atualmente, em diversos municípios, um verdadeiro frenesi relativo às intervenções públicas, na tentativa de recuperar espaços históricos; porém, pode-se indagar se essas propostas de resgate da história, identidade e memória dos patrimônios não é uma necessidade de reafirmar o próprio sistema. A simples recuperação estética não leva a um resultado satisfatório; falta recuperar os símbolos historicamente importantes e significativos e devolver de fato o espaço público ao cidadão. A criação de vias exclusivas para pedestres, alargamento de calçadas, alterações físicas para circulação de portadores de deficiência física, ciclovias, canaletas exclusivas para ônibus, implementação de espaços adequados para o comércio informal, áreas de convivência e lazer, restaurantes populares e outras soluções podem ser implementadas, num processo de revitalização das áreas centrais, com o objetivo de tornar esse espaço um ambiente agradável a todos, devolvendo-o à população, considerando-se como vital a participação efetiva dos diversos agentes envolvidos. Diante disso, o espaço público da rua deve ser rediscutido de maneira a abarcar sua realidade histórico-social e cultural, sua construção subjetiva, uma espacialidade onde as pessoas se identificam por símbolos comuns, representações e mediações, para que se possa efetivamente torná-lo um espaço de sociabilidade, um espaço humanizado. / The emphasis in broaching a thesis subject which reflections and analysis deal whith the relationship between men and downtown areas, having the “street" as a reference, reflects a concern, as a urban space researcher, of a problem that grows in our cities, the gradual lost of recreational and social public spaces. This urban problematic has been growing for decades as the so called “common space" is rapidly depreciated and lost its functions, as a consequence of the “public men loss of importance" process and the growth of the private sphere in the urban areas, leading to a growing search of private spaces for shopping, leisure, culture and sports, therefore supporting the strong advance of the private iniciative in (re)adequacy the public space and its “management". This research had as objective the evaluation of the currently use of the public space in downtown areas of the city, identifying the variables that led and still lead to its fast depreciation and loss of function, therefore proposing adequated means of use and destination of this space for the hole population. It was observed that there is no real concearn in creating public policies that lead to a readaptation of the public space in the downtown areas, giving it back to all citizens, indistinctly, for those confront with priorities that preserve the values of the medium and high income groups. Therefore it's necessary to recompose the pedestrian public space. The public departments responsible for the transport planning and management, and also for the urban planing, should work together with the community and researchers of various areas of knowledge to create a forum where new forms of intervention in the urban space may be created, integrating technical, social, economical and cultural aspects and helping to rethink the city in short, medium and long terms. It is currently seen, in many cities, a great effort to recuperate the historical spaces; but it can be asked if those attempts of rescuing the history, the identity and the memory of this patrimony is not just a necessity of reassuring the system itself. The mere esthetical recuperation does not lead to a satisfactory result; it lacks the recuperation of the historically important and significant symbols and the real devolution of the public space to the citizens. The creation of pedestrian streets, the widening of sideways and its adequation to handicaps, bicycles streets, bus tracks, implementation of informal commerce spaces, sociability and leisure areas, popular restaurants and others solutions can be implemented, in a process of revitalizing downtown areas, with the objective of transforming this space in a pleasant ambient, giving it back to the population, considering as vital the effective participation of all involved agents. Considering that, the public space in the streets must be rediscussed in a search for its historical-social and cultural reality, its subjective construction, a place where people can identify with each other by common symbols, representations and mediations, so that it can be effectively transformed in a socializing space, a humanized space.

Made available in DSpace on 2016-08-10T10:50:11Z (GMT). No. of bitstreams: 1 Adriane Tavares Borges.pdf: 5728173 bytes, checksum: dcfbf094b8acbf93b957f9b1cf2a5e80 (MD5) Previous issue date: 2015-08-14 / The present study aims at understanding urban mobility in Goiânia and the contributions provided by the corridors created for public transportation. The concept and history of mobility were researched, going back to the formation of urban settlements, the evolution of the means of transportation and the negative impact generated by the increasingly intense use of motorized transport. Based on significant experiences at global, national and local scales, the study highlighted several alternatives used to mitigate the negative externalities created by the excessive use of motorized vehicles in the cities. Giving priority to the pedestrias, to non-motorized means of transportation and public transport were some of the strategies used in the three scales. In Goiânia, as well as in other cities, priority was given to public transport, by the creation of exclusive or preferential bus corridors. The results point to a better ordering of the traffic, with a more inclusive and equitable distribution of the street space. / Compreender a mobilidade urbana em Goiânia e a contribuição dada pelos corredores de transporte coletivo de passageiros constituiu-se no objetivo principal deste trabalho. Para tanto, buscou-se uma base conceitual e histórica da mobilidade, contemplando a formação das urbanidades, a evolução dos meios de transporte e os impactos negativos gerados a partir da intensificação do uso de transporte motorizado. Por meio de experiências expressivas em escala mundial, nacional e local, o estudo apontou diversas alternativas utilizadas para combater as externalidades negativas geradas pelo excedente veicular motorizado em circulação nas cidades. Dentre as estratégias utilizadas, nas três escalas, foi constatada a priorização de pedestres, de modos não motorizados e do transporte coletivo. Em Goiânia, assim como em outras cidades, por meio da estruturação de corredores de transporte coletivo, exclusivos e preferenciais, procurou-se estabelecer a priorização do transporte coletivo. Os resultados apontaram um melhor ordenamento no trânsito, com uma distribuição do espaço viário mais inclusiva e equânime.