Thesis (M.S.)--University of Michigan, 1974. / Typescript (photocopy). Includes bibliographical references (leaves 65-69). Also issued in print.

Thesis (M.S.)--University of Michigan, Ann Arbor, 1971. / Typescript (photocopy). Includes bibliographical references (leaves 48-51). Also issued in print.

Thesis (M.S.)--University of Michigan, 1974. / Typescript (photocopy). eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 65-69).

Thesis (M.S.)--University of Michigan, Ann Arbor, 1971. / Typescript (photocopy). eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 48-51).

Thesis--Universidad Autónoma de Guadalajara, 1977.

Thesis--Universidad Autónoma de Guadalajara, 1977.

Indiana University-Purdue University Indianapolis (IUPUI) / A study was conducted on the effects in a rhesus monkey of increasing the surface area of pulpal tissue available for revascularisation and regeneration of nerves after replantation of permanent teeth. Four teeth were replanted and used for controls, including two with incomplete apical development. Twelve teeth with completed apical development were replanted immediately after apical modification to increase the surface area of exposed pulp. The technique consisted of creating a facial and lingual groove in the apical region and exposing additional pulpal tissue. Radiographs were taken periodically and the replanted teeth were stable during the study period. The monkey was sacrificed after 93 days. The first hypothesis, that the apically modified teeth would sustain a healthy periodontium clinically for a period of ninety days, was disproved. Histological sections of the teeth and their supporting tissues showed varying amounts of root resorption and ankylosis. All of the apically modified teeth showed pulp necrosis, while three of the four control teeth had reestablished blood and vascular supplies and appeared vital. Ingrowth of granulation tissue was seen in the replanted teeth with pulp necrosis including one control tooth which had failed to revascularize. The second hypothesis, that the apically modified teeth would demonstrate significantly more apical revascularisation and nerve regeneration than the control teeth, was also disproved. In conclusion, the apical modification technique as performed to increase the area available for regeneration of nerves and vessels was not a success. As expected, however, immediate replantation of avulsed teeth resulted in reestablishment of periodontal membrane attachments.

Made available in DSpace on 2014-06-11T19:31:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2004Bitstream added on 2014-06-13T19:40:58Z : No. of bitstreams: 1 moro_ma_dr_araca.pdf: 3174992 bytes, checksum: e66ab0779c0d8d9f38619779521c7bdc (MD5) / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / Reimplantes experimentais de incisivos centrais e intermédios ou laterais, foram efetuados em cães, após 45 minutos da extração e contidos com fios de aço e resina fotopolimerizável. Sete dias após, realizou-se as intervenções endodônticas através da obturação dos canais radiculares com os cimentos Sealapex ou Endofill ou com a aplicação das medicações intracanal de hidróxido de cálcio ou hidróxido de cálcio associado à calcitonina. Como controle, alguns canais, após pulpectomia e preparo biomecânico, permaneceram vazios durante todo o período experimental. Decorridos mais 14 dias, os curativos foram trocados e as contenções removidas. Finalmente, após mais 40 dias, as medicações intracanais foram novamente trocadas e os resultados avaliados histologicamente, quatro meses após o início do tratamento. A análise estatística dos escores atribuídos aos diversos eventos histomorfológicos considerados demonstrou que os grupos de dentes reimplantados e tratados com o hidróxido de cálcio, hidróxido de cálcio associado à calcitonina ou com o cimento Sealapex proporcionaram resultados semelhantes entre si e superiores ao grupos Endofill e controle, os quais tiveram comportamentos semelhantes. / Experimental reimplants of central and intermediate incisors were made in dogs, 45 minutes after the extraction and contained with steel strings and photo-polymerable resin. Seven days after, it had been made the root canal with the endodontic interventions through the filling of the root canal with the cements Sealapex or Endofill or with the application of the intracanal medications calcium hydroxide or calcium hydroxide associated to calcitonin. As control, some canals, after pulpectomy and biomechanical prepare, remained empty through the whole experimented period. Fourteen more days passed, the contention were changed and the restrictions removed. Finally, after 40 more days, the intra-canal medications were changed again and the results evaluated histologically, four months after beginning of the treatment. The statistical analysis of the scores attributed to the several considered histomorphological events demonstrated that the teeth groups replanted and treated with calcium hydroxide, calcium hydroxide associated to calcitonin or the cement Sealapex had similar results and superior to those treated with Endofill and control, which results had similar behavior.

Post Traumatic Cold Intolerance is the most common, and often the most prominent disabilityfrom hand trauma. The discomfort caused by cold is believed to be linked to a dysfunction o f thedigital vasoregulation, but its pathophysiology is poorly understood. Cold induced vasospasm, i.e.the pathologically increased reactivity o f the digital vessels to cold, is commonly found in handsthat have sustained trauma, especially with damage to vascular and neural structures. This thesis is based upon a series o f clinical and laboratory studies on cold induced vasospasm andcold intolerance in 35 patients treated for digital amputation. The replanted digit was used as astudy model, since it represents a body part which at the moment o f reconstruction is devoid o f allinnervation. Replantations were performed according to two different principles o f vascularreconstruction; using long or short vessel grafts. Finger Systolic Pressure (FSP) was used as aparameter o f digital vasoregulation at different temperatures, and cold intolerance was assessedusing a logarithmic rating scale (Borg). Non-injured fingers and amputation stumps were used ascontrols. Clinical and laboratory investigations were performed at different intervals from oneweek to three years after the reconstruction. During the first two weeks following replantation, whole body cold exposure, or cooling o f thereplanted part to 10°C, did not cause serious spasm in the replanted vessels. Follow upinvestigations demonstrated that a cold related vasospastic tendency is established inapproximately 60% o f the replanted parts within one year after trauma. The once establishedpathologic vasoregulation, is unlikely to normalize spontaneously. Whether a cold related arterialspasticity will develop in the replanted digit or not, is not related to the surgeon's choice o ftechnique for vascular reconstruction. Cold related arterial spasticity was more common inamputation stumps than in replanted digits, Our findings suggest that there is a pathologicalreaction to cold in the distal palm vessels but the nature o f this disturbance is not clear. All patients developed some degree o f Post Traumatic Cold Intolerance. Approximately 60% o fthe patients stated that some improvement took place, but none o f the patients was free o f coldintolerance 1-7 years after the injury. Patients with a pathological cold induced vasospasm is likelyto present with severe cold intolerance, which indicates that the vasospasm is involved as one o fthe causes o f Post Traumatic Cold Intolerance. / <p>S. 1-48: sammanfattning, s. 51-110: 5 uppsatser</p> / digitalisering@umu

Thesis (doctoral)--Karolinska Institutet, 1985. / Added t.p. with thesis statement inserted. Includes bibliographical references.