Implantation of a left ventricular assist device (LVAD) is a potential treatment in terminal heart failure. Right ventricular (RV) failure is a severe complication in these patients and sometimes requires additional placement of a right ventricular assist device (RVAD). RVAD implantation, however, is an invasive treatment associated with both increased mortality and morbidity. The aim of this thesis was to study whether partial volume exclusion of the RV through a modified Glenn shunt or cavoaortic shunt could treat severe RV failure. The ultimate goal would be to use it as an alternative to a RVAD in RV failure during LVAD therapy. Swine were used as the model animal in all studies. In Study I, experimental RV failure was induced by ischemia, and verified by hemodynamic measurements and genetic expression. Treatment with a modified Glenn shunt reduced venous stasis and improved hemodynamics in general. In Study II, experimental RV failure was induced by the same method as in Study I. Treatment with a cavoaortic shunt in addition to LVAD therapy proved to reduce venous stasis and improved hemodynamics in general, which was feasible with preserved oxygen delivery despite cyanotic shunting. In Study III, experimental RV failure was induced by pulmonary banding, and verified by hemodynamic measurements and genetic expression. Treatment with a modified Glenn shunt reduced venous stasis but did not improve hemodynamics in general compared with a control group. In Study IV, the effects of LVAD therapy and subsequent treatment with a modified Glenn shunt on the normal RV function were studied. It demonstrated that LVAD therapy can put strain on the RV by increasing stroke work and end-diastolic volume, and that these effects can be reversed by treatment with a modified Glenn shunt during LVAD therapy. In conclusion, partial volume exclusion through a modified Glenn shunt or cavoaortic shunt is a feasible treatment of experimental RV failure. Thus, it could potentially be used as an alternative treatment to a RVAD in severe RV failure during LVAD therapy.

Since the face forms over the brain in the course of embryonic development, facial anthropometry may reflect brain structure. The motor functions of each side are controlled by the side of the brain opposite the body side. The purpose of this study was to establish whether a correlation exists between handedness and the location of the external auditory meatuses, as a possible consequence of brain asymmetry. Facial photographs were taken of 78 volunteers. Straws, placed in the external ear canals, were used to mark the external auditory meatuses. The level of the top of each meatus was measured from each volunteer's visual plane, as established by connecting the center of a point of reflected light in each pupil. Each volunteer was also given the Edinburgh Laterality Inventory (Durden-Smith and DeSimone, 1984:53) to determine "true" handedness (50 right-handers and 28 left-handers). Right-handers, as determined by either writing hand or laterality inventory, were found to exhibit a greater tendency for the left auditory meatus to be lower. Specifically, 68% of the right-handers, as opposed to 39% of the left-handers, exhibited a left external auditory meatus located at a lower position on the skull than the right meatus. This was significant at the 0.05 level. The differences in external auditory meatal distances from the visual plane were greater on the left in right-handers 68% of the time, equal 10%, and greater on the right 22% of the time. A reverse correlation for the right asymmetry for left-handers was not found. Instead, for the left-handed sample a nearly even distribution for meatal location was found: 39% left asymmetry, 29% symmetry, and 32% right asymmetry.The study strongly supported the hypothesis that right-handers have a significant tendency for left asymmetry in location of the external auditory meatuses. The study did not support the hypothesis that the meatal asymmetry correlates to the side opposite the handedness of the individual. Of-perhaps greater significance is the finding that the percentages of left asymmetry of both groups match the brain asymmetry percentages found by Galaburda (1984:15) for the planum temporale, an extension on the upper surface of the temporal lobe of the brain. The level of the external auditory meatuses, as a reflection of brain asymmetry, may serve as an external measurement of the location of Wernicke's area which is located near the planum temporale and has a major role in speaking and comprehension of the spoken word and in reading and writing. Simple techniques for locating the language centers of the brain would be an advantage in developing education plans and teaching strategies for students with each of the possible hemispheric dominance patterns. / Department of Anthropology

A name identity task was used to assess the language processing abilities of the right hemisphere of the brain. Ten undergraduates participated in each of three experimental conditions; nouns presented below threshold, nouns presented above threshold and verbs presented above threshold. Significant priming effects occurred when a picture of a noun or verb was presented above threshold and followed by a word which named the picture. The priming effect for nouns presented below threshold was not significant. No hemispheric asymmetries were found for the recognition of nouns or verbs.

Nordic right wing populism began in Denmark with the requisite growth in the political and societal power of the Danish People’s Party during the Liberal-Conservative coalition government from 2001 to 2011. As the number of immigrants and asylum-seekers from Middle Eastern countries continues to grow, the “other,” the definition of which is a perceived threat against an ill-defined “people,” is increasingly understood by the Danish People’s Party as Muslim immigrants and their descendants. This thesis will use both a wide array of literature and evidence from an original research project using a Danish Prison as a loose microcosm for Danish society. The research traces the influence of the Danish People’s Party on public policy. This thesis will conclude that blatant Islamophobia has seeped into the following sectors of Danish policy: the media, social services and the refugee and asylum system. Denmark, while being an internationally revered example of good governance, represents the dangerous proliferation of illiberalism in the modern, small welfare state in response to globalization.

Intellectual property rights (IPRs) are becoming increasingly important due to their inevitable link to technology and economic development. This highlighted role has resulted in the emergence and development of over-protections that are beyond the ideal scope of IPRs. As the scope of IPRs expands, competition concerns are also intensifying and, as a result, the interface between IP and competition law is expanding in new directions. To address these new developments, trans-Atlantic jurisdictions have developed new policies based on the general provisions of their competition laws. Canada’s current policy toward the IP/competition law interface is affected by the existence of a unique section in its Competition Act, section 32, which directly refers to the anti-competitive usage of IPRs. Despite section 32’s long presence in the Act and its role as a basis of the Competition Bureau’s analysis of the IP/competition law interface in Canada, this section has not been judicially considered to date. This thesis re-examines the role of section 32 and explores some of the reasons behind its current obsolescence. The main claim of this thesis is that the current interpretations of the role of section 32 are not as broad as envisaged in the statute. On the one hand, the Competition Bureau’s interpretation in the Intellectual Property Enforcement Guidelines (IPEGs) limits the scope of section 32 to the unilateral refusal to license IPRs. The approach that the Bureau has adopted toward the unilateral refusal to license is more in line with the American restrictive approach, which allows very limited scope for competition law interventions in the IP realm. From the author’s point of view, such a restrictive approach is not consistent with the underlying principles of Canadian competition policies. On the other hand, section 32 has not been amended since 1935. This has led to the generation of some procedural restrictions in the application of this section. The author claims that the procedural requirements of section 32 need to be amended in order to parallel the modernization of the Competition Act that has occurred over the last few decades. / Graduate

In 1996, a new left of centre party emerged in Japan called the Democratic Party of Japan (DPJ) and effectively replaced the Japan Socialist Party (JSP) as the main opposition party. This thesis asks what conditions caused this realignment and how the DPJ differs from the JSP. An increasing distrust and disinterest of politics and politicians has meant that the non-aligned voter in Japan forms the largest group of the electorate. Every party has lost support, but the left faced the worst drop of support. With the end of the Cold War, and the intensifying call for Japan to reassess its role on the World stage, the traditional ideology of the Japanese left, which has become synonymous with peace and preservation of the Peace Constitution, has lost its stabilising effect on the party and on its supporters. The labour unions, which were once the key mobilisational force for the left-wing parties at election time, began to question their relationship with the JSP and found new links to government. Simultaneously, they were also losing members so mobilisation of voters for the left also declined. Finally, a new electoral system did not reward the opposition as much as the LDP. Overall, the mobilisation of the electorate has become increasingly difficult for the Japanese left as a result of these factors. The DPJ has had to find ways of dealing with them and also has had to create its own identity. The way in which the party has dealt with this is by 'widening out' its types of candidate and using new methods to attract support. Furthermore, the DPJ has become more aware of its party coherence and has ensured that party unity is maintained even when ideological disputes occur.

The right in Chile has been crucial to the democratic politics of the country ever since the development of the party system. In the period covered by this thesis (1939- 1964) the Chilean right faced the combined challenge of reformist governments and the emergence of mass political parties on the left. This thesis describes the Chilean right as being composed by political parties, entrepreneurial associations and a leading newspaper, El Mercurio. which represented and expressed the interests, thoughts and common perspectives of the right as a whole. This thesis argues that the right in Chile was able not only to survive the reformist governments of the 1940s, but that it remained very influential politically and as an economic force. The strategies it successfully carried out were those of negotiation and co-optation, which rested in the right's congressional power. With the advent of populism at the beginning of the 1950s, the argument goes, the right faced new threats, especially the discredit of political parties and of Congress conceived as the arena par excellence for negotiation and compromise. The danger came both from within the right itself, threatening to divide it, and from populist governments, which put at risk the right's sources of influence. Thus, the rightist sectors had to develop new political strategies, which in essence pointed towards the formulation of a project of capitalist modernisation centered in private enterprise and free markets. With the election of Jorge Alessandri --an entrepreneurial figure-- as President of the Republic, the right had the opportunity to put into practice its novel economic ideas. In the long run, though, the results were negative. The thesis analises the political dimension of this failure. Once its project collapsed, the right became ideologically marginal, just at a time when Chilean politics had become strongly ideological as well as reformist if not revolutionary. This explains why the leaders of the long established parties of the right, the Conservatives and Liberals, dissolved themselves in 1965. Finally this dissertation speculates on the right at the present time looking for elements of continuity and change between today's right and the one studied for the 1939-1964 period.

No description available.

This essay examines the indirect effects of the local strength of the Swedish Democrats on refugee acceptance in the Swedish municipalities. With statistical methods this essay has aimed to investigate if such effects exist and by using statistical data from three periods of time - 2002, 2006 and 2010 – the investigation has been able to measure effects over time. Based on former research and reasonable expectations the hypothesis for the essay claims that the Swedish Democrats has got an indirect effect upon the refugee acceptance. With the statistical analyses made, the essay is able to conclude that the strength of the Swedish Democrats in municipality elections as well as the change of this strength between the elections does have a negative effect upon refugee acceptance in the Swedish municipalities. With this conclusion, the idea of the Swedish Democrats as an isolated and insignificant party is questioned.

This thesis analyzes the rationale, appropriateness and value of the available legal and regulatory means to deal with genetic discrimination in the context of insurance. Insurance is used as a paradigm case for discussing the legal means to address the concerns related to the impact of new medical technologies. A new framework is proposed for evaluating the potential impact of such new technologies on people's ability to participate fully in social life and to have access to important social goods without unfair discrimination based on certain inherited traits. / A "thick" contextual method is used, which involves a detailed description of the medical, social, and legal context of the debate. The approach is based on Michael Walzer's theory of justice, which posits that in assessing the fairness of the distribution of a particular good, one must take into account the nature of the good as determined by the specific socio-historical context in which it obtains its shared meaning. Walzer's theory is used in the thesis to critically analyze the regulatory and legislative means introduced in several countries to curb genetic discrimination. It is further argued that Walzer's contextual analysis resembles the approach taken by the Canadian Supreme Court in the context of anti-discrimination law. Canadian human rights law is analyzed in detail to describe how genetic discrimination could be dealt with under the current provisions and how human rights law can be used to create conditions of substantive equality. The thesis concludes with an analysis of various legal and regulatory options to deal with genetic discrimination and its impact on human rights in the Canadian context. The establishment of a regulatory body is proposed, with the mandate to review the appropriateness of the use of new tests in the context of insurance. I argue that this review process, and the contextual analysis that should be involved in this process, would constitute a useful step towards creating conditions for substantive equality, not only for those who are genetically disabled, but for all those who are affected by real or perceived disabling conditions and stigmatizing traits.