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11	The efficacy of hydroxyurea in decreasing transfusion requirements and hospital admission in children with sickle cell disease Mackinnon, Diane 20 May 2014 (has links) The burden of sickle cell disease lies in Africa where resources are limited . Hydroxyurea may be an affordable treatmentoption for these patients. Purpose To asses whether hydroxyurea has any effect in reducing vaso-occlusive crises, hospitalization and transfusion requirements in children with homozygous sickle cell a n a e m i a . To e v a l u a t e t h e t o x i c i t y o f h y d r o x y u r e a . M e t h o d s T h i s i s a r e t r o s p e c t i v e , d e s c r i p t i v e s t u d y o f c l i n i c a l and h a e m a t o l o g i c a l o u t c o m e s i n c h i l d r e n w i t h s i c k l e c e l l a n a e m i a t r e a t e d w i t h h y d r o x y u r e a . R e s u 1t s Ten p a t i e n t s w e r e e v a l u a t e d . H y d r o x y u r e a d e c r e a s e d t h e r a t e o f v a s o - o c c 1 u s i o n and d e c r e a s e d t h e t r a n s f u s i o n r e q u i r e m e n t s . The c l i n i c a l and h a e m a t o l o g i c a l b e n e f i t s w e r e g r e a t e s t when f o e t a l h a e m o b l o b i n was m a x i m a l . T h e r e was no s h o r t - t e r m t o x i c i t y . C o n c l u s i o n H y d r o x y u r e a a m e l i o r a t e s symptoms in sickle cell disease. On going studies are n e e d e d t o a s s e s s l o n g - t e r m e f f e c t s . Anemia, Sickle Cell--therapy
12	Impact of carrier screening on pregnant women's knowledge of sickle cell anemia Moxley, Kristan Michelle. January 2008 (has links) Thesis (M.S.)--Case Western Reserve University, 2008. / [School of Medicine] Department of Genetics. Includes bibliographical references.
13	Positional and functional approaches towards the cloning of a QTL for heterocellular HPFH on chromosome 6q23 Stephens, Philip James January 2000 (has links) No description available. 572.8 Leukemia; Sickle-cell; Haemoglobin
14	Biophysical analysis of receptor mediated erythrocyte adherence in sickle cell anemia : involvement of infection and hemodynamics Smolinski, Paula A. 12 1900 (has links) No description available. Sickle cell anemia Erythrocytes Hemodynamics
15	Effects of a classroom-based direct instruction reading intervention for young children with sickle cell disease. Newton, Sandra Claire, January 2004 (has links) Thesis (M.A.)--University of Toronto, 2004. / Adviser: Thomas Humphries. Sickle cell anemia in children. Reading
16	Determination of the variation in the iTRAQ protein profiling technique / Vanarsa, Kamala, January 2008 (has links) Thesis (M.S.)--University of Texas at Dallas, 2008. / Includes vita. Includes bibliographical references (leaf 22) Proteins Proteins Sickle cell anemia.
17	Proteomic modifications of the sickle red blood cell membrane caused by hydroxyurea / Ghatpande, Swati Sudhir, January 2008 (has links) Thesis (Ph.D.)--University of Texas at Dallas, 2008. / Includes vita. Includes bibliographical references. Sickle cell anemia. Proteomics. Proteins
18	Universal metastability of sickle hemoglobin polymerization / Weng, Weijun. Ferrone, Frank A. January 2008 (has links) Thesis (Ph.D.)--Drexel University, 2008. / Includes abstract and vita. Includes bibliographical references (leaves 152-157).
19	A microrheological study of sickle hemoglobin polymerization / Zakharov, Mikhail N. Ferrone, Frank A. January 2009 (has links) Thesis (Ph.D.)--Drexel University, 2009. / Includes abstract and vita. Includes bibliographical references (leaves 98-101). Physics. Sickle cell anemia. Rheology.
20	Neuropsychological functioning in preschool-aged children with sickle cell disease : the role of illness-related and psychosocial factors / Tarazi, Reem A. January 2004 (has links) Thesis (Ph. D.)--Drexel University, 2004. / Includes abstract and vita. Includes bibliographical references (leaves 106-117).

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