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The treatment of paediatric asthma in the private health care sector of South Africa : a retrospective drug utilisation review / J. MoutonMouton, Jeanine January 2010 (has links)
Asthma is the most common chronic disease among children worldwide. The prescribing
patterns of the medication used to treat asthma in South Africa, as well as the prevalence of
paediatric asthma are of interest and need to be investigated.
A drug utilisation review was performed to determine the prevalence of asthma, and in
particular paediatric asthma in a section of the private health care sector of South Africa. The
prescribing patterns of asthma medication were investigated according to different
demographic factors, such as gender, geographical area and prescriber type. Data from a
medical claims database were extracted and processed to reveal the different prescribing
patterns from 1 January 2005 to 31 December 2008. Medication from the MIMS®
pharmacological groups 10.2 and 10.4 were used as a basis for asthma medication. Patients
had to use at least one medicine item from one of these groups to be included in the study.
The prevalence of asthma in the general population showed an increase from 2005 to 2008.
The prevalence of asthma as a part of the total database according to the number of patients
increased from 23.01% in 2005 (n=347342) to 24.72% in 2008 (n=240854), although the
number of patients on the total database decreased from 2005 to 2008. When investigating
the number of prescriptions that were dispensed during 2008, asthma prescriptions
comprised 7.16% (n=484983) of all prescriptions and the number of asthma medicine items
that were dispensed made up 3.72% (n=611139) of the total number of medicine items
dispensed in 2008.
Paediatric asthma was divided into two age groups for the purpose of this study namely, 0 -
4 years of age and older than 4 years, but younger or equal to 11 years of age ( >4 - 11
years), according to a previous study done by the National Heart Lung and Blood Institute
(NHLBI). The results from the data confirmed that the prevalence of asthma was higher in
the younger age group. The number of patients using asthma medication in the 0 - 4 years
age group comprised 44.40% (n=11306) of the total number of patients in this age group on
the database in 2008, compared to 32.84% (n=28347) in the >4 - 11 years age group.
Asthma was more common among male patients, whether they were included in the
paediatric groups or not. The geographical distribution of paediatric asthma seemed to be
connected to the provinces without coastlines and different mining facilities. The combination of asthma medication with antibiotics and systemic corticosteroids were investigated and it
was concluded that antibiotics that were used for respiratory tract infections were prescribed
the most frequently to asthma patients.
The refill–adherence rates of patients with asthma were not satisfactory when considering
that asthma is a chronic disease. The average adherence rate for all the asthma products
that were brought into account when calculating the refill–adherence rate was 60.95%. A rate
above 90% indicates optimal patient adherence.
In conclusion this study determined that asthma has a significant prevalence among children
in South Africa. The prescribing patterns for the different medication used in the treatment of
asthma were investigated and recommendations for further research in this field of study
were made. / Thesis (M.Pharm. (Pharmacy Practice))--North-West University, Potchefstroom Campus, 2011.
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Comparison of waist circumference distribution of South African black children from different study populations / Boitumelo Stokie MotswagoleMotswagole, Boitumelo Stokie January 2010 (has links)
Studies in both children and adults indicate that waist circumference (WC), a measure of abdominal obesity is closely related to cardiovascular risk factors. The accurate identification of abdominally obese children in health screening programmes for early intervention is of importance. There are, however, concerns about using international definitions for screening purposes because in most instances these have been derived from Western populations and, therefore, may have limited usefulness to children in other parts of the world. When these cut–off points are used in developing countries, they ignore the fact that the growth patterns of children and burdens of disease vary between countries. Due to lack of population specific cut–off points for children in the developing world it may be tempting and convenient to use the same cut–off points as for children in developed countries, but such a practice runs the risk of exporting failure. Ideally, a screening tool should have both high sensitivity and specificity, and these are important considerations in choosing the definition for the detection of childhood abdominal obesity. High sensitivity is necessary to avoid failure of identifying obese children and high specificity of the screening tool ensures that non–obese children are not misclassified as obese, which may otherwise lead to unnecessary treatment and psychosocial implications of stigmatisation. Failure to identify the abdominally obese child may have more serious consequences than misclassification, since it results in an increase in adult morbidity and mortality. Therefore, the main aim of this thesis was to examine fat distribution patterns of black South African (SA) children in relation to health risk. The specific objectives were to: compare the body composition of black stunted and non–stunted children from two rural communities in South Africa; to describe and compare the age and sex specific WC percentile distribution for black SA children from different study populations and compare the WC percentile distribution with those for African–American (A–A) children and to assess the diagnostic accuracy of waist–to–height ratio (WHtR) as a marker for high blood pressure, a cardiovascular risk factor in SA children.
Findings of this study demonstrated increased total adiposity in non–stunted children, but trends of increased central adiposity, measured as WHtR in stunted children. This warrants further investigation on this relationship among children older than 13 years in the African context where many children are stunted. The differences observed between the different data sets and between SA and A–A children suggest that nationally representative data should be used to develop age, sex and ethnic specific WC percentiles for this population. The results indicate clearly that the median WC of children from SA studies is smaller than those of A–A children, with a medium to large effect size for the difference. Results also suggest concern with respect to high WC values (> 80 cm) among some children. The recommended universal WHtR cut–off value of 0.5 for assessment of cardiovascular risk is not suitable for black SA children because it had low sensitivity in predicting high blood pressure. The absence of locally developed cut–off values for WC and WHtR for children warrants research due to the associations between being overweight and obese and disease outcomes. It is fundamental to detect risk at an early stage so that appropriate intervention can be initiated timeously. / Thesis (Ph.D. (Nutrition))--North-West University, Potchefstroom Campus, 2011.
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Validation of a coping self–efficacy scale in an African context / Mabet M. van WykVan Wyk, Mabet Marie January 2010 (has links)
Various scales have previously been developed to measure coping strategies (Taylor & Stanton, 2007; Devonport & Lane, 2006; Stapelberg, 1999) or self–efficacy (Carroll et al., 2005; Chen et al., 2001; Tipton & Worthington, 1984); and some of them have been validated in a South African context, but the validation of a coping self–efficacy scale as a single measurement has not been conducted in an African context. Therefore, the aim of this study was to validate Chesney et al.’s 2006 Coping Self–Efficacy Scale (CSE) in an African context.
A multicultural convenience sample of 2 214 South African adolescents and adults, including both male and female participants, participated in this study. Measuring instruments such as the Coping Self–Efficacy Scale (CSE) (Chesney, Neilands, Chambers, Taylor & Folkman, 2006), the Mental Health Continuum - Short Form for adults (MHC–SF) (Keyes et al., 2008), the New General Self–Efficacy Scale (NGSE) (Chen, Gully & Eden, 2001; 2004), the Fortitude Questionnaire (FORQ) (Pretorius, 1998), the Patient Health Questionnaire: Depression Symptoms (PHQ–9) (Kroenke, Spitzer & Williams, 2001) and the General Health Questionnaire (GHQ) (Goldberg & Hillier, 1979) were used in this study. Criterion–related validity of the CSE was established. Construct validity was determined by conducting confirmatory and exploratory factor analyses as well as SEM on the CSE.
Results indicated a Cronbach alpha reliability coefficient of 0.87 and satisfactory inter–item correlations ranging from 0.19–0.21. Criterion–related validity was satisfactory. Confirmatory analysis indicated a good fit and exploratory factor analysis confirmed the three major factors similar to Chesney et al.’s (2006) findings. Construct validity was further supported by SEM analysis, which confirmed the three–factor structure.
The CSE can be viewed as reliable and valid for use in further research in the African context. Future studies should validate this scale in various population groups, with translated versions of the scale and with randomly selected groups. / Thesis (M.A. (Research Psychology))--North-West University, Potchefstroom Campus, 2011.
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Consumers' preferences for private and national brand food products / L. WymaWyma, Louise January 2010 (has links)
Introduction: The importance of brands and the competition between private and national brands in different food categories increased in recent years. According to literature, except for packaging and price, there is virtually no difference between the contents of food products in the majority of private and national brands. Private brands are usually cheaper than national brands. Previous research indicated consumers’ preferences for private and national brand food products to differ between various products and in different regions. Objective: The aim of this study was thus to determine the relationship between consumers’ brand preferences for different food products, in relation to their demographics and psychographics in a South African context. Setting: A mall intercept, interviewer administered questionnaire was used as a quantitative method in this study in Potchefstroom in a South African context. Consumers’ preferences for private and national brand food products in different product categories were explored, using preference, psychographics and demographical questions simultaneously. Results: Respondents in this study preferred to purchase national brands in all products categories except for cooking oil. Considering eight psychographic factors that were extracted by exploratory factor analysis, two factors could be associated with positive reactions, while neutral reactions were evident for six factors. Respondents being indecisive on the majority of factors could be due to the fact that national brands were preferred for most products by respondents in the present study. Conclusions: Although brand preference depended on demographics and psychographics in previous research, the present study did not find significant relationships with psychographics when different products were used. Although a combination of demographic factors (mainly gender, education level, home language and employment status) could be useful in determining brand preference when used with specific products, home language and education level seem to be the most important factors. Therefore, brand preference depended on specific demographics for each product, while psychographic factors did not play a significant role. This implied that brand preference research should be product and region specific using specific demographic variables. / Thesis (M. Consumer Science)--North-West University, Potchefstroom Campus, 2011.
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A comparative study of arthropod diversity on conventional and Bt–maize at two irrigation schemes in South Africa / Truter J.M.Truter, Jean-Maré January 2011 (has links)
The purpose of the research was to explore the experiences of educators regarding the
training for the implementation of inclusive education in a Full Service school. A qualitative
research design was chosen, using a case study. Three methods of gathering data were
used, namely individual interviews, focus group interviews and observations. The study was
conducted in a primary schools in the North West province that was converted into a fullservice
school in 2008. The findings indicated that educators demonstrated
misunderstanding of the Screening, Identification, Assessment and Support strategy. The
misunderstanding can be ascribed to the kind of training educators received. The training
lacked in–depth content and practical demonstration. Recommendations on the content and
the dynamics of the training process are made. The overarching recommendation on the
dynamics of the training indicated that the training should be revisited for improved methods
of training. / Thesis (M.Sc. (Environmental Science))--North-West University, Potchefstroom Campus, 2011.
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The cardiovascular profile of HIV–infected South Africans of African descent : a 5–year prospective study / Botha S.Botha, Shani January 2011 (has links)
With great appreciation, I would like to accentuate the substantial contributions of the following
people who made this project possible:
To Dr. CMT Fourie (my supervisor), Prof. JM van Rooyen (my co–supervisor) and Prof. AE
Schutte (my co–supervisor) whose gracious advise, patient guidance, commitment and support
have enabled me to plan, analyse, interpret and write this project in a scientific manner. It has
been an educational experience for me, thank you.
To Mr. LS Wyldbore for the language editing of this dissertation.
I thank all the participants, researchers, field workers and supporting staff of the PURE study.
The financial assistance of the National Research Foundation (DAAD–NRF) towards this
research is hereby acknowledged.
A special thanks to my parents, sister, Albert, family and friends, thank you for the never–ending
love, support, patience and understanding that you gave me throughout this project.
Last, but not the least, a special thank to God for giving me the opportunity, talent,
determination and endurance to complete this project. / Thesis (M.Sc. (Physiology))--North-West University, Potchefstroom Campus, 2012.
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A comparison of the characteristics of internationalising SMEs in South Africa and the BRIC countries / Lamprecht J.L.D.Lamprecht, Jacobus Lodewicus du Plessis January 2011 (has links)
SMEs are important for a country's economy, since they provide benefits such as entrepreneurship, employment, exports and productivity to an economy. An economy that shows substantial growth is usually characterised by a strong and growing SME sector. South African SMEs need to grow to create jobs and benefit the South African economy. One way that SMEs can become strong and grow is through internationalisation. Firms are internationalising faster than ever before (because of advances in telecommunications and transportation) and internationalisation theories that can provide practical guidance to firms are more important today than in the past.
The motivation of the study was to identify the areas that the South African government can develop in order to transform the economy into an emerging economy that can be on par with the BRIC countries. SMEs make up a large part of the BRICS economies and they grow through exports. In order to be on par with the BRIC countries, it is necessary to compare South African exporting and non–exporting SMEs with those in the BRIC countries. This will help to identify areas where South African SMEs' competitiveness can improve, especially in South–South trade. The competitiveness of SMEs involved in exporting also tends to improve. Therefore, if SMEs' competitiveness improves, it may be less risky for them to internationalise, which can lead to them being able to export more successfully, grow as a result of exporting and so contribute to employment.
The primary objective of the study was to make a comparison between the characteristics of internationalising SMEs in South Africa and the BRICS countries. Data was obtained from the World Bank Enterprise surveys to conduct an empirical analysis on firms in the BRICS countries. The empirical analysis provided descriptive statistics on internationalising firms and SMEs in the BRICS countries. The descriptive statistics was used to make a comparison between the characteristics of internationalising SMEs in the BRICS countries (primary objective). South Africa has the highest percentage of
exporting SMEs, followed by India, Brazil, Russia and China. China had the most exporting SMEs with an internationally recognised certification. The top managers of Chinese exporting SMEs are higher educated than those in India and South Africa. SMEs in Russia internationalise at by far the youngest age and thus are likely to follow the rapid international theories. South African SMEs had the highest average age, meaning that SMEs first are established in the domestic market before they internationalise through exports.
Internationalisation has become an important strategy for firms that want to achieve further growth, but it is also very tough to survive in the international market. An interesting finding of this study was that the two obstacles South Africa had in the top 5 namely, crime, theft and disorder, and electricity were not a top 5 obstacle for any of the other BRIC countries.
Another objective of the study was to empirically determine the characteristics of internationalising SMEs in South Africa. SMEs in South Africa are more likely to internationalise through exports if they are, amongst others, older (longer established in the domestic market), have a larger market share in the South African domestic market, have a top manager with experience and a higher education level (some university training minimum) and have less competitors in the South African domestic market.
The comparison between the characteristics of internationalising SMEs of the BRICS countries provided several lessons for the South African government and exporting SMEs. The areas or aspects that the South African government need to develop in order to transform the economy into an emerging economy that can compete with the BRIC countries, include assisting SMEs in exporting at an earlier age, improving the education levels of top managers in SMEs, increasing the national market share of SMEs and lessening, or even eliminating, obstacles like crime, theft and disorder as well as electricity. These aspects, together with the characteristics of internationalising SMEs in South Africa, are vital to improve SME competitiveness. Therefore, if SMEs' competitiveness improves, then it may be less risky for them to internationalise, which
can lead to them being able to export more successfully, grow as a result of exporting and so contribute to employment. / Thesis (M.Com. (International Trade))--North-West University, Potchefstroom Campus, 2012.
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The role of securitisation and credit default swaps in the credit crisis : a South African perspective / White W.White, Johannes Petrus Lodewikus January 2011 (has links)
The financial crisis that struck financial markets in 2008 was devastating for the global
economy. The impact continues to be felt in the market - most recently in sovereign defaults.
1 There are many questions as to the origin of the crisis and how the same events
may be prevented in the future. This dissertation explores two financial instruments: securitisation
and credit default swaps (CDSs) and attempts to establish the role they played
in the financial crisis. To fully understand the events that unfolded before and during the
crisis, a sound theoretical understanding of these instruments is required. This understanding
is important to discern the future of stable financial markets and to gain insight
into some of the potential risks faced by financial markets.
The South African perspective regarding securitisation, CDSs and the global financial crisis
is an important field of study. The impact of the crisis on South Africa will be explored in
this dissertation, as well as, the effect of the crisis on South Africa's securitisation market
(which has proved healthy and robust over the first part of the new millennium despite
the global slowdown of these instruments) and the CDS market. A key goal of this work is
to establish whether or not CDSs have been used in South Africa to hedge the credit risk
component of bonds linked to asset–backed securities (ABSs). This will provide an indication
of the maturity of the South African credit risk transfer (CRT) market and how South
Africa compares to more developed financial markets regarding complexity, regulation,
sophistication and market sentiment. Through the exploration and understanding of these
concepts, the efficacy of emerging economies to adapt to globalisation, and how welcome
financial innovation has proved to be in emerging markets will be addressed. / Thesis (M.Com. (Risk management))--North-West University, Potchefstroom Campus, 2012.
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An analysis of business–related factors on small businesses / Irma KotzéKotzé, Irma January 2010 (has links)
The study was based on the evaluation of specific business–related factors concerning small
businesses in the formal sector.
The purpose of this study was to gain a clear understanding of the current education level of
employees in the small business industry. Income and business related costs applicable to
small businesses and formal business support was also evaluated in terms of its availability
to small businesses. By means of investigation it was possible to conclude to what extent
small businesses contribute towards economic growth in South Africa. The South African
government is definitely aware of the important role which small businesses play in economic
growth and poverty reduction.
Small businesses were analysed to determine the education level of both employees and
business owners. The contribution which business owners made to training and development
of their employees was also investigated. The income over a period of five years were
analysed to determine the financial sustainability of the businesses. The impact of business
related costs and the global economic recession were also investigated to determine the
future sustainability of small businesses. The empirical research was conducted at a financial
institution in Klerksdorp to assess the contribution which small businesses made towards
economic growth and development.
Small businesses' contribution towards education and training must be reconsidered as
limited opportunities exist within small business for training. Small business owners cannot
afford to send their employees away to obtain training and mainly make use of on–the–job
training. SETAS must focus more on small businesses when it comes to training and
alternative training methods must be reconsidered. The implementation of complex labour
legislation and the minimum wages law make unskilled labour very expensive for small
business owners. This must be reconsidered as small businesses cannot afford to employ
additional employees. Formal business support available to small business owners were
perceived not to be marketed very well although the lack of internet access may contribute to
the limited knowledge in this regard. The South African government must reconsider its
strategy to utilize small businesses to create jobs and to develop skills. / Thesis (M.B.A.)--North-West University, Potchefstroom Campus, 2011.
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The treatment of paediatric asthma in the private health care sector of South Africa : a retrospective drug utilisation review / J. MoutonMouton, Jeanine January 2010 (has links)
Asthma is the most common chronic disease among children worldwide. The prescribing
patterns of the medication used to treat asthma in South Africa, as well as the prevalence of
paediatric asthma are of interest and need to be investigated.
A drug utilisation review was performed to determine the prevalence of asthma, and in
particular paediatric asthma in a section of the private health care sector of South Africa. The
prescribing patterns of asthma medication were investigated according to different
demographic factors, such as gender, geographical area and prescriber type. Data from a
medical claims database were extracted and processed to reveal the different prescribing
patterns from 1 January 2005 to 31 December 2008. Medication from the MIMS®
pharmacological groups 10.2 and 10.4 were used as a basis for asthma medication. Patients
had to use at least one medicine item from one of these groups to be included in the study.
The prevalence of asthma in the general population showed an increase from 2005 to 2008.
The prevalence of asthma as a part of the total database according to the number of patients
increased from 23.01% in 2005 (n=347342) to 24.72% in 2008 (n=240854), although the
number of patients on the total database decreased from 2005 to 2008. When investigating
the number of prescriptions that were dispensed during 2008, asthma prescriptions
comprised 7.16% (n=484983) of all prescriptions and the number of asthma medicine items
that were dispensed made up 3.72% (n=611139) of the total number of medicine items
dispensed in 2008.
Paediatric asthma was divided into two age groups for the purpose of this study namely, 0 -
4 years of age and older than 4 years, but younger or equal to 11 years of age ( >4 - 11
years), according to a previous study done by the National Heart Lung and Blood Institute
(NHLBI). The results from the data confirmed that the prevalence of asthma was higher in
the younger age group. The number of patients using asthma medication in the 0 - 4 years
age group comprised 44.40% (n=11306) of the total number of patients in this age group on
the database in 2008, compared to 32.84% (n=28347) in the >4 - 11 years age group.
Asthma was more common among male patients, whether they were included in the
paediatric groups or not. The geographical distribution of paediatric asthma seemed to be
connected to the provinces without coastlines and different mining facilities. The combination of asthma medication with antibiotics and systemic corticosteroids were investigated and it
was concluded that antibiotics that were used for respiratory tract infections were prescribed
the most frequently to asthma patients.
The refill–adherence rates of patients with asthma were not satisfactory when considering
that asthma is a chronic disease. The average adherence rate for all the asthma products
that were brought into account when calculating the refill–adherence rate was 60.95%. A rate
above 90% indicates optimal patient adherence.
In conclusion this study determined that asthma has a significant prevalence among children
in South Africa. The prescribing patterns for the different medication used in the treatment of
asthma were investigated and recommendations for further research in this field of study
were made. / Thesis (M.Pharm. (Pharmacy Practice))--North-West University, Potchefstroom Campus, 2011.
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