by Ricky, Lap Kei Chan. / Thesis submitted in: December 1997. / Thesis (M.Phil.)--Chinese University of Hong Kong, 1998. / Includes bibliographical references (leaves [123-129]). / Abstract also in Chinese. / Table of Contents --- p.i / Abstract --- p.v / Chinese Abstract --- p.vii / Acknowledgements --- p.ix / Statement of Originality --- p.x / List of Figures --- p.xi / List of Tables --- p.xiv / INTRODUCTION / Chapter Chapter 1 --- Introduction --- p.2 / Chapter 1.1. --- Urinary Bladder Wall Thickness --- p.2 / Chapter 1.2. --- Urinary Bladder Shape --- p.3 / BACKGROUND / Chapter Chapter 2 --- Embryology --- p.6 / Chapter 2.1. --- Embryology of the Urinary Bladder --- p.6 / Chapter Chapter 3 --- Anatomy --- p.9 / Chapter 3.1. --- Basic Anatomy of Urinary Bladder --- p.9 / Chapter 3.2. --- "Artery, Vein, Lymphatic and Nervous Supply of Urinary Bladder" --- p.18 / Chapter Chapter 4 --- Pathology --- p.20 / Chapter 4.1. --- Cystitis --- p.20 / Chapter 4.2. --- Parasitic Infestation --- p.21 / Chapter 4.3. --- Catheter Induced Cystitis --- p.21 / Chapter 4.4. --- Chemotherapy Induced Cystitis --- p.22 / Chapter 4.5. --- "Calculus, Clot and other Debris" --- p.23 / Chapter 4.6. --- Bladder Outlet Obstruction --- p.23 / Chapter 4.7. --- Neurogenic Bladder --- p.24 / Chapter 4.8. --- Bladder Neoplasm --- p.24 / Chapter 4.9. --- Metastasis from Neighboring Malignancy --- p.26 / Chapter Chapter 5 --- Pathophysiology --- p.27 / Chapter 5.1. --- Mechanism causing Urothelial Edema during Cystitis --- p.27 / Chapter 5.2. --- Muscular Hypertrophy and associated Cystitis during Bladder Outlet Obstruction --- p.29 / Chapter 5.3. --- Neoplastic Disease --- p.30 / Chapter Chapter 6 --- Previous Works in Urinary Bladder Wall Thickness --- p.31 / Chapter 6.1 --- Previous Findings --- p.31 / MATERIALS AND METHODS / Chapter Chapter 7 --- Aims of the Study --- p.34 / Chapter 7.1. --- Bladder Wall Thickness --- p.34 / Chapter 7.2. --- Bladder Configuration --- p.34 / Chapter Chapter 8 --- Methodology --- p.35 / Chapter 8.1. --- Choice of Imaging Modality for Bladder Wall Thickness Measurement --- p.35 / Chapter 8.2. --- Study Group Selection Criteria --- p.38 / Chapter a) --- Criteria for the selection of normal subject --- p.38 / Chapter b) --- Criteria for the selection of subject with bladder disorder --- p.40 / Chapter 8.3. --- Equipment --- p.41 / Chapter 8.4. --- Bladder Volume Estimation --- p.43 / Chapter 8.5. --- Measuring Method --- p.45 / Chapter a) --- Bladder volume estimation --- p.45 / Chapter b) --- Bladder wall thickness measurement --- p.47 / Chapter c) --- Bladder configuration observation --- p.50 / Chapter 8.6. --- Technical Consideration --- p.54 / Chapter a) --- Bladder wall thickness measurement and bladder volume estimation in normal subject --- p.54 / Chapter b) --- Bladder wall thickness measurement in subject with bladder disorder --- p.57 / Chapter c) --- Bladder shape observation --- p.59 / RESULTS AND DISCUSSION / Chapter Chapter 9 --- Results and Discussion --- p.61 / Chapter 9.1. --- Pilot Studies --- p.61 / Chapter 9.2. --- Data Grouping for Bladder Wall Thickness in Normal Subjects --- p.68 / Chapter 9.3. --- Bladder Wall Thickness --- p.70 / Chapter 9.4. --- Bladder Wall Thickness Variation within Individual Age Group --- p.74 / Chapter 9.5. --- Bladder Wall Thickness Variation between Different Age Groups --- p.81 / Chapter 9.6. --- Relationship of Bladder Wall Thickness against Bladder Volumein Different Genders --- p.84 / Chapter 9.7. --- Comparison with Publication --- p.87 / Chapter 9.8. --- Nomograms of Bladder Wall Thickness in Different Age Groups --- p.89 / Chapter 9.9. --- Establishment of the Normal Upper Limit of Bladder Wall Thickness in Different Age Groups --- p.92 / Chapter 9.10. --- Data Grouping for Bladder Wall Thickness in Subjects with Bladder Disorder --- p.93 / Chapter 9.11. --- Measuring Method for Bladder Wall Thickness in Potentially Abnormal Subjects --- p.94 / Chapter 9.12. --- Distribution of Bladder Wall Thickness of Diseased Subjectsin Nomograms --- p.95 / Chapter 9.13. --- Data Grouping in Bladder Configurations Observation --- p.108 / Chapter 9.14. --- Distribution of Bladder Configurations in Transverse Section of Ultrasound Images --- p.110 / Chapter 9.15. --- Distribution of Bladder Configurations in Longitudinal Section of Ultrasound Images --- p.114 / CONCLUSIONS / Chapter Chapter 10 --- Conclusions --- p.120 / Chapter 10.1. --- Urinary Bladder Wall Thickness --- p.120 / Chapter 10.2. --- Urinary Bladder Configuration --- p.122 / References --- p.R1-R7 / Appendix / Appendix A Graphs of bladder wall thickness against bladder volume of all individual sub-age groups --- p.A1-A23 / Appendix B Graphs of bladder wall thickness against bladder volume of all individual sub-age groups (between male and female) --- p.B1-B23 / Appendix C Nomograms of bladder wall thickness in different age groups --- p.C1-C8 / Appendix D Distribution of bladder configurations in transverse ultrasound images of different age groups --- p.D1-D4 / Appendix E Distribution of bladder configurations in longitudinal ultrasound images of different age groups --- p.E1-E4

Issued also as thesis, Univ. de Lyon. / "Bibliographie": p. [207]-219.

No description available.

Diss. (sammanfattning) Göteborg : Göteborgs universitet, 2007. / Härtill 4 uppsatser.

Issued also as thesis, Paris.

Afhandling--Copenhagen. / "Also published as a supplement to volume 16, 1969 of Danish Medical Bulletin." Summary in Danish. Bibliography: p. 139-150.

Afhandling--Copenhagen. / "Also published as a supplement to volume 16, 1969 of Danish Medical Bulletin." Summary in Danish. Bibliography: p. 139-150.

Made available in DSpace on 2014-06-11T19:23:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-02-29Bitstream added on 2014-06-13T19:30:19Z : No. of bitstreams: 1 vasconcellos_al_me_jabo.pdf: 364796 bytes, checksum: faa48323c2af56deebee2125936ba7e6 (MD5) / Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) / Os cães podem ser acometidos por diversos tipos de doenças vesicais incluindo cistites, neoplasias e urolitíases, dentre outras. A variedade da etiopatogenia e das formas de apresentação clínica das cistites constitui um fator complicante para o diagnóstico. O presente estudo teve por objetivo evidenciar a importância da inclusão de alguns exames complementares com vistas ao diagnóstico correto das afecções vesicais. Foi realizado um estudo prospectivo para o diagnóstico da condição vesical de 46 animais, machos e fêmeas, selecionados ao acaso dentre os encaminhados para check-up de rotina e os pacientes com algum tipo de sinal ou achado sugestivo de doença vesical. A avaliação consistiu de exame clínico completo e exame específico do trato urinário incluindo urinálise, exame microbiológico da urina por meio de cultura em lâmina e cultura tradicional, e avaliação vesical por meio do exame ultrassonográfico. Os dados foram submetidos à analise estatística descritiva e ao Teste Exato de Fisher para associações. Os resultados evidenciaram que os sinais clínicos e os achados de sedimentoscopia da urina não são específicos, dada a semelhança das manifestações das diversas doenças vesicais. A urocultura e a ultrassonografia vesical foram exames complementares decisivos que possibilitaram o diagnóstico dos casos de cistite bacteriana (n=32) bem como das doenças vesicais coexistentes (n=3) e das doenças vesicais não infecciosas (n=2). Concluiu-se que o exame clínico de rotina, mesmo que a urinálise seja incluída, não é apropriado para diagnosticar doenças vesicais e que a urocultura e o exame ultrassonográfico contribuem de modo decisivo para o diagnóstico correto dos cães com ou sem sinais clínicos de cistite / Dogs can be affected by several types of bladder diseases including cystitis, neoplasia, and urolithiasis, among others. The variety of etiopathology and clinical presentation forms of cystitis is a complicating factor for the diagnosis. The aim of this study was to show the importance of some additional exams inclusion in order to achieve the correct diagnosis for bladder diseases. A prospective study was conducted for bladder condition diagnosis in 46 animals, males and females, taken for random among dogs referred for routine checkup and the patients with some type of signs or finding suggestive of bladder disease. The evaluation included complete clinical exam and specific examination of the urinary tract including urinalysis, urine microbiologic examination by commercially manufactured screening urine culture kit and traditional culture, and ultrasound bladder evaluation. The data were analyzed by descriptive statistic and Fisher’s Exact Text. The results showed that clinical signs and urine sediment findings are nonspecific, given the similarity of the bladder diseases manifestations. The urine culture and bladder ultrasound were decisive additional exams that enable the diagnosis of bacterial cystitis (n=32), as well as of the coexisting bladders diseases (n=3) and non infectious bladder diseases (n=2). It was concluded that the routine clinical examination, even when the urinalysis is included, isn`t appropriated for bladder diseases diagnosis, moreover the urine culture and the ultrasonographyc exam contribute in a decisive way for the correct diagnosis of dogs showing or not clinical signs of cystitis

Thesis--Rigshospitalet, University of Copenhagen. / Summary in English and Danish. Bibliography: p. 219-[225]

Made available in DSpace on 2014-06-11T19:33:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-08-27Bitstream added on 2014-06-13T20:05:14Z : No. of bitstreams: 1 nascimentoepontes_mg_dr_botfm.pdf: 553102 bytes, checksum: 6f4ebc00fc0583f012e1a99ab95ffefe (MD5) / Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) / Toxicam / Urinary bladder carcinomas (UBC) frequently recur. During the intervals “free‐ofneoplasia”, between the initially diagnosed tumor and its recurrences, there are not undisputable histological alterations in the mucosa, although some studies have reported DNA damage in urothelial cells. In order to understand developmental characteristics of UBC, primary tumors and their recurrences were cytogenetically evaluated for their genomic expression by High Resolution Comparative Genomic Hybridization (HR‐CGH). Tumors and their respective recurrences, six low‐grade (LG) and five high‐grade (HG) cases, provided 20 tissue samples that were submitted to laser microdissection capture followed by HR‐CGH. HR‐CGH profiles had two different analyses – all tumors altogether or classified according to their respective histological grades. Both comparisons showed high frequency (80%) of gains in 11p12 and losses in 16p12, in agreement with the literature that indicate alterations of 11p and 16p in UBC recurrences. These findings suggest that those chromosome regions contain putative oncogenes and tumor suppressor genes critical for urinary bladder carcinogenesis. Within a same patient genomic profile showed high agreement between tumors and their respective recurrences, i.e., tumors from the same patient showed a large number of common losses and gains. The high similarities of genomic alterations in successive tumors from the same patient suggest that a stable genomic profile was established in UBCs and their recurrences. Besides, during the “free‐of‐neoplasia” intervals, negative urinary bladder washes were submitted to Fluorescent in situ Hybridization (FISH) to detect quantitative alterations in centromeres 7 (n=21 samples), 17 (n= 21) and 9p21 (n=36). No numerical alterations... (Complete abstract click electronic access below)