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Lernspezifische Sicherheitsmechanismen in Lernumgebungen mit modularem LernmaterialGraf, Frank. January 2002 (has links) (PDF)
Darmstadt, Techn. Universiẗat, Diss., 2002.
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Localization, disorder, and polarization fields in wide-gap semiconductor quantum wellsMayrock, Oliver. January 2001 (has links) (PDF)
Berlin, Humboldt-University, Diss., 2001.
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Ontology and the Semantic WebZhang, Jane January 2007 (has links)
This paper discusses the development of a new information representation system embodied in ontology and the Semantic Web. The new system differs from other representation systems in that it is based on a more sophisticated semantic representation of information, aims to go well beyond the document level, and designed to be understood and processed by machine. A common theme underlying these three features, i.e., turning documents into meaningful interchangeable data, reflects a rising use expectation nurtured by modern technology and, at the same time, presents a unique challenge for its enabling technologies.
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Persistent links, one solution to a common problemBigwood, David 06 1900 (has links)
Discusses persistent links or PURLs as a tool for linking.
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A visual metaphor-based tool for a search-engine user interfaceGrewal, Ratvinder Singh January 2001 (has links)
No description available.
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Wide baseline matching with applications to visual servoingTell, Dennis January 2002 (has links)
No description available.
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An Analysis of Genome-Wide Association Studies to Produce Evidence Useful in Guiding Their Reporting and SynthesisYurkiewich, Alexander John 08 February 2012 (has links)
Introduction The present study evaluated reported methodological characteristics of GWAS, investigating relationships between reported methodological characteristics and outcomes observed.
Methods GWAS were identified from NHGRI’s catalogue of GWAS (2005 to 2009). Multivariate meta-regression models (random effects) were produced to identify the impact of reported study characteristics and the strength of relationships between the variables and outcomes.
Results The summary odds ratios for replication components of GWAS in cancer was 1.34 (95% CI 1.25, 1.43) and neuropsychiatric disorders was 1.43 (95% CI 1.30, 1.57). Heterogeneity was accounted for by nature of the control group, relationship between case/control groups, whether cases/controls were drawn from the same population, if data was a primary collection or a build on pre-existing data, if quality assurance was reported, and if the study reported power/sample size.
Conclusion Evidence supports the existence of variability in reporting, with index components demonstrating less variability than replication components in the GWAS.
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An Analysis of Genome-Wide Association Studies to Produce Evidence Useful in Guiding Their Reporting and SynthesisYurkiewich, Alexander John 08 February 2012 (has links)
Introduction The present study evaluated reported methodological characteristics of GWAS, investigating relationships between reported methodological characteristics and outcomes observed.
Methods GWAS were identified from NHGRI’s catalogue of GWAS (2005 to 2009). Multivariate meta-regression models (random effects) were produced to identify the impact of reported study characteristics and the strength of relationships between the variables and outcomes.
Results The summary odds ratios for replication components of GWAS in cancer was 1.34 (95% CI 1.25, 1.43) and neuropsychiatric disorders was 1.43 (95% CI 1.30, 1.57). Heterogeneity was accounted for by nature of the control group, relationship between case/control groups, whether cases/controls were drawn from the same population, if data was a primary collection or a build on pre-existing data, if quality assurance was reported, and if the study reported power/sample size.
Conclusion Evidence supports the existence of variability in reporting, with index components demonstrating less variability than replication components in the GWAS.
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An updated object oriented bovine QTL viewer and genome-wide bovine meta-analysisSalih, Hanni 15 May 2009 (has links)
Waves of bovine genomic data have been produced as a result of the bovine
genome sequencing projects. In addition to the massive amounts of genomic sequence,
significant annotation including single nucleotide polymorphisms, sequence tagged sites
and haplotype blocks have been produced by the Bovine HapMap Project. Furthermore,
many agriculturally significant traits in cattle such as milk yield and carcass weight are
measured on a quantitative scale and have been genetically mapped as quantitative trait
loci (QTL). QTL data can be used to generate another form of bovine annotation linking
phenotype to genotype. However, it is impossible for humans to be able to analyze
genomic scale data without computer based tools. Bioinformatic tools have been shown
to greatly increase productivity and improve efficiency when dealing with large data
sets.
My dissertation presents an integrated, extensible database that houses SNPs,
STSs, haplotypes, and QTL. The database is presented to researchers through a
restructured, object oriented Bovine QTL Viewer that displays multiple levels of bovine annotation synergistically. Evaluation of use of the viewer was performed using a
survey based approach and measured quantitatively.
In addition, the QTL data from the database was used to analyze the frequency of
gene ontology (GO) annotations within QTL regions. QTL regions were divided into 8
trait based groups. GO terms were counted within each category of QTL and in non-
QTL regions of the genome. Top level GO term frequencies were generated from the
counts and these frequencies were compared between QTL and non-QTL portions of the
genome. Furthermore, specific sets of GO terms believed to be related to QTL
categories were also used to determine if QTL regions were enriched for genes annotated
with such GO terms. As a result, we determined that gene density varied significantly
across QTL regions and that many QTL categories showed GO term frequency
differences that could be related to the trait’s biology. Furthermore, our selected GO
term sets were shown to be significantly enriched in some QTL categories.
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Wide baseline matching with applications to visual servoingTell, Dennis January 2002 (has links)
No description available.
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