In this thesis, X-ray and optical observations of accretion powered pulsars are presented. By using archival RXTE observations we work on the X-ray spectral and pulse timing analysis of 4U 1538-52, 4U 1907+09, SMC X-1 to have more detailed information about their orbital and spin parameters. For 4U 1538-52 and SMC X-1, we determined new orbital epochs. By using long term pulse history of 4U 1907+09, we were able to work spin-down trend of the system and also calculate the change in the spin-down rate. Using Fermi/GBM observations we can monitor bright accreting pulsar systems. We are producing long term histories of pulse frequency and flux of 20 continuosly monitoring systems. Adding Swift/BAT observations to GBM observations, for 4U 1626-67, we did reveal the characteristics belong to spin-down trend before and spin-up behaviour after torque reversal seen in 2008 February. Two newly discovered IGRJ06074+2205 and IGRJ01583+6713 sources are identified as X-ray binary systems and we found parameters of them like distance, magnitudes, by using both optical photometric and spectroscopic observations.