This study used an archival data set of 26 healthy adult immigrants from a sub-Saharan African country to the United States (Mage 39.0, SD = 11.36; Meducation 16.33, SD = 2.88; 40.7% male). Additional archival data was used for 32 healthy African American adults (Mage 34.06, SD = 11.18; Meducation 16.16, SD = 2.49; 53.1% male). A bivariate correlation indicated that acculturation to African culture, as measured by the mBIQ (M 49.29, SD = 8.66), was significantly positively correlated with ethnicity, r = .632, p = .000, ηp2 = 0.399. Two-way ANOVAs revealed that African Americans were able to name more animals than African immigrants (F(1, 54) = 4.82, p = 0.32, ηp2 = 0.82) and exhibited greater organizational skills during a task of cognitive set shifting and problem solving than African immigrants, regardless of level of acculturation (F(1, 54) = 4.47, p =.039, ηp2 = 0.078). In contrast, African immigrants scored higher than African Americans on indigenous fruit (F(1, 54) = 7.60, p =.008, ηp2 = 0.123) and object naming (F(1, 54) = 5.59, p =.022, ηp2 = 0.094). Results of the study concluded that there are small variance effects in language tasks as well as strategy-based approaches to tasks of novel problem solving. Implications of these findings are discussed relative to future research as well as clinical practice in the assessment of culturally dissimilar people across a racially homogenous population by pushing the field forward with diversified approaches to neuropsychological testing.