Thesis (Ph. D.)--Ohio State University, 2009. / Title from first page of PDF file. Includes bibliographical references (p. 91-100).

Includes bibliographical references (p. 64-71).

The performance of optical imaging systems relies on control of aberrations that can arise from limitations in the design, manufacture, or alignment. This dissertation addresses the form of aberrations that occur for misaligned reflective systems, such as telescopes. The relationship between a characteristic set of field-dependent aberrations and the misalignments that cause them is systematically explored. A comprehensive technique that quantifies field performance for a 5-mirror system is given, using Monte Carlo analysis to provide confidence levels of image quality as functions of manufacturing and alignment errors. This analysis is an example of the "forward problem"— determining optical performance of a system if the errors are assumed. The inverse problem — determining the state of alignment based on measurements of performance — is more difficult. The solution to the inverse problem for a multiple mirror system requires an understanding of the complex coupling between many degrees of freedom (tilt, decenter, despace, shape error) of the optical elements and field-dependent aberrations.This work builds on previous treatment of field dependent optical aberrations from Tessieres, Thompson, Shack, Buchroeder and others. A basis set of field-dependent aberrations orthogonal over both field and pupil are developed here and used to describe systems with misaligned and misshapen optics. This description allows complete representation of high order and non-linear effects. The functional form of aberrations that are characteristic of mirror tilt, shift, and deformation show some useful patterns that provide insight to the fundamental effects of misalignment.The use of singular value decomposition to create orthogonal combinations of the field dependent aberrations provides a powerful tool for evaluating a system and for estimating the state of alignment using wavefront measurements. The following optical systems are evaluated to investigate the linear coupling between misalignment and the resulting field dependent aberrations:* 2-mirror telescopes, evaluating well-understood effects for an axisymmetric system and developing the relationships for an unobscured system.* 4-mirror correctors for a spherical primary telescope.The tools and methods are applied to reflective optical systems for astronomical telescopes, but the methods are general and can be useful for any optical imaging system.

A low-clay version of fine translucent china was designed to have desired properties and acceptable behaviour during manufacture. Low-clay contents of 10 to ISw/o were employed to reduce the deterious effects of preferential clay particle alignment and its adverse effect on colour. For example, alignment of clay particles in cast wares causes anisotropic drying and firing shrinkages and these cause distortion. Replacing clay with a pre fired body with low Fe and Ti contents, as in the present case, allowed a very white material to be produced. The prefired body was made with calcium carbonate, aluminium trihydroxide, quartz and a small fluxing addition of an hydrated magnesIUm carbonate. Desification of a whiteware is enhanced by increasing volume fraction of the viscous liquid and reducing by its viscosity. Both of these also enhance sagging. Consequently, compositional change cannot on its own lead to the favourable combination of high density, required to give translucency, with little sagging, that will allow wares to be fired without significant distortion. It was found by trail and error that use of finer particles reduced the sagging occurring in the densification heat treatment and enhanced densification. This finding allowed the body to be designed so that it densified without sagging excessively. After establishing this important result, an iterative approach was employed to produce a ware that was very white, translucent, had the required thermal expansion coefficient for glaze fitting, shrank acceptably during the first firing and did not sag during the second firing that stimulated glost firing. The finding on sagging was applied to an anorthite/mullite porcelain body that was under development. This body was also made with a low-clay content and the same prefired body. This whitware has potential to replace bone china and hard porcelain for use in the servere service conditions of hotels and restaurants. It has a higher fracture toughness than hard porcelain but has the same scratch resistant glaze and is more resistant to thermal shock. The sagging of the anorthite/mullite porcelain was substantially reduced while the body was densified. This was achieved by using a combination of finer particles and a reduction in the liquid-phase content that developed during firing.

No description available.

The ability of the human eye to change its overall refractive power so that people can focus on objects both far and near is termed accommodation. Research into how the eye automatically changes its accommodation, demands an instrument capable of tracking the accommodation with fine resolution and adequate corner frequency. An instrument capable of tracking the ocular accommodation is called an optometer. Reports of earlier optometers show that optometers using the older Scheiner principlecan have the required precision and dynamics required to track the micro fluctuations accommodation. However optometers using the Scheiner principle require precise alignment to the patient’s pupil to be maintained throughout the measurement time. Previous optometers have used the radiation reflected from the patient’s cornea (calledthe corneal reflection) to initially align the optical axis of the optometer to the centre of the patient’s pupil. Since the Scheiner principle optometer uses radiant energy reflected from the patient’s retina to make a refractive measurement, the idea of using this same radiant energy for patient alignment is investigated. Earlier optometers have blocked the corneal reflection from reaching the photodetectors for the retinal reflection using a small fixed light stop. Since it is not possible to use a fixed light stop if the retinal reflection is used for alignment, the feasibility of using crossed linear polarizers is experimentally evaluated. The results showed that about78% of the radiant energy reflected from the front lens of an artificial eye could be eliminated using crossed linear polarizers. Whether the Scheiner principle measurement of refraction of an artificial eye could be done with 78% of the front lens (corneal) reflection removed was investigated. The results were not conclusive. There was not a measureable indication of when the refraction of the experimental optometer matched that of the artificial eye. The experimental optometer system attempts to use a servo controlled mirror system to move the optical axis of the optometer so that it coincides with the optical axis of an artificial eye. The design, development and testing of the mirror system is described. The mirror system enables the optometer to perform a two dimensional scan over the pupil plane of the patient’s eye or an artificial eye. During the scanning, the total radiant power reflected can be measured. For the optometer to be aligned using radiation reflected from the retina, a scan of the pupil plane of should reveal the pupil boundaries. This was experimentally demonstrated to work. Unfortunately time limitations did not permit further development of an automatic eye alignment and tracking system.

The ability of the human eye to change its overall refractive power so that people can focus on objects both far and near is termed accommodation. Research into how the eye automatically changes its accommodation, demands an instrument capable of tracking the accommodation with fine resolution and adequate corner frequency. An instrument capable of tracking the ocular accommodation is called an optometer. Reports of earlier optometers show that optometers using the older Scheiner principlecan have the required precision and dynamics required to track the micro fluctuations accommodation. However optometers using the Scheiner principle require precise alignment to the patient’s pupil to be maintained throughout the measurement time. Previous optometers have used the radiation reflected from the patient’s cornea (calledthe corneal reflection) to initially align the optical axis of the optometer to the centre of the patient’s pupil. Since the Scheiner principle optometer uses radiant energy reflected from the patient’s retina to make a refractive measurement, the idea of using this same radiant energy for patient alignment is investigated. Earlier optometers have blocked the corneal reflection from reaching the photodetectors for the retinal reflection using a small fixed light stop. Since it is not possible to use a fixed light stop if the retinal reflection is used for alignment, the feasibility of using crossed linear polarizers is experimentally evaluated. The results showed that about78% of the radiant energy reflected from the front lens of an artificial eye could be eliminated using crossed linear polarizers. Whether the Scheiner principle measurement of refraction of an artificial eye could be done with 78% of the front lens (corneal) reflection removed was investigated. The results were not conclusive. There was not a measureable indication of when the refraction of the experimental optometer matched that of the artificial eye. The experimental optometer system attempts to use a servo controlled mirror system to move the optical axis of the optometer so that it coincides with the optical axis of an artificial eye. The design, development and testing of the mirror system is described. The mirror system enables the optometer to perform a two dimensional scan over the pupil plane of the patient’s eye or an artificial eye. During the scanning, the total radiant power reflected can be measured. For the optometer to be aligned using radiation reflected from the retina, a scan of the pupil plane of should reveal the pupil boundaries. This was experimentally demonstrated to work. Unfortunately time limitations did not permit further development of an automatic eye alignment and tracking system.

Thesis (Ph. D., Bioinformatics and Computational Biology)--University of Idaho, August 2008. / Major professor: James A. Foster. Includes bibliographical references (leaves 90-94). Also available online (PDF file) by subscription or by purchasing the individual file.

Thesis (Ph. D.)--Virginia Commonwealth University, 2009. / Prepared for: Dept. of Medicinal Chemistry. Title from title-page of electronic thesis. Bibliography: leaves 126-138.

The field of medical image analysis has been rapidly growing for the past two decades. Besides a significant growth in computational power, scanner performance, and storage facilities, this acceleration is partially due to an unprecedented increase in the amount of data sets accessible for researchers. Medical experts traditionally rely on manual comparisons of images, but the abundance of information now available makes this task increasingly difficult. Such a challenge prompts for more automation in processing the images.In order to carry out any sort of comparison among multiple medical images, onefrequently needs to identify the proper correspondence between them. This step allows us to follow the changes that happen to anatomy throughout a time interval, to identify differences between individuals, or to acquire complementary information from different data modalities. Registration achieves such a correspondence. In this dissertation we focus on the unified analysis and characterization of statistical registration approaches.We formulate and interpret a select group of pair-wise registration methods in the context of a unified statistical and information theoretic framework. This clarifies the implicit assumptions of each method and yields a better understanding of their relative strengths and weaknesses. This guides us to a new registration algorithm that incorporates the advantages of the previously described methods. Next we extend the unified formulation with analysis of the group-wise registration algorithms that align a population as opposed to pairs of data sets. Finally, we present our group-wise registration framework, stochastic congealing. The algorithm runs in a simultaneous fashion, with every member of the population approaching the central tendency of the collection at the same time. It eliminates the need for selecting a particular referenceframe a priori, resulting in a non-biased estimate of a digital template. Our algorithm adopts an information theoretic objective function which is optimized via a gradientbased stochastic approximation process embedded in a multi-resolution setting. We demonstrate the accuracy and performance characteristics of stochastic congealing via experiments on both synthetic and real images. / PhD thesis