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PROGRAM EVALUATION OF A MOBILE DECENTRALIZED PHARMACY PILOT PROGRAM.Banner, Elizabeth Gleeson. January 1983 (has links)
No description available.
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Advanced modelling and simulation of water distribution systems with discontinuous control elementsPaluszczyszyn, Daniel January 2015 (has links)
Water distribution systems are large and complex structures. Hence, their construction, management and improvements are time consuming and expensive. But nearly all the optimisation methods, whether aimed at design or operation, suffer from the need for simulation models necessary to evaluate the performance of solutions to the problem. These simulation models, however, are increasing in size and complexity, and especially for operational control purposes, where there is a need to regularly update the control strategy to account for the fluctuations in demands, the combination of a hydraulic simulation model and optimisation is likely to be computationally excessive for all but the simplest of networks. The work presented in this thesis has been motivated by the need for reduced, whilst at the same time appropriately accurate, models to replicate the complex and nonlinear nature of water distribution systems in order to optimise their operation. This thesis attempts to establish the ground rules to form an underpinning basis for the formulation and subsequent evaluation of such models. Part I of this thesis introduces some of the modelling, simulation and optimisation problems currently faced by water industry. A case study is given to emphasise one particular subject, namely reduction of water distribution system models. A systematic research resulted in development of a new methodology which encapsulate not only the system mass balance but also the system energy distribution within the model reduction process. The methodology incorporates the energy audits concepts into the model reduction algorithm allowing the preservation of the original model energy distribution by imposing new pressure constraints in the reduced model. The appropriateness of the new methodology is illustrated on the theoretical and industrial case studies. Outcomes from these studies demonstrate that the new extension to the model reduction technique can simplify the inherent complexity of water networks while preserving the completeness of original information. An underlying premise which forms a common thread running through the thesis, linking Parts I and II, is in recognition of the need for the more efficient paradigm to model and simulate water networks; effectively accounting for the discontinuous behaviour exhibited by water network components. Motivated largely by the potential of contemplating a new paradigm to water distribution system modelling and simulation, a further major research area, which forms the basis of Part II, leads to a study of the discrete event specification formalism and quantised state systems to formulate a framework within which water distribution systems can be modelled and simulated. In contrast to the classic time-slicing simulators, depending on the numerical integration algorithms, the quantisation of system states would allow accounting for the discontinuities exhibited by control elements in a more efficient manner, and thereby, offer a significant increase in speed of the simulation of water network models. The proposed approach is evaluated on a number of case studies and compared with results obtained from the Epanet2 simulator and OpenModelica. Although the current state-of-art of the simulation tools utilising the quantised state systems do not allow to fully exploit their potential, the results from comparison demonstrate that, if the second or third order quantised-based integrations are used, the quantised state systems approach can outperform the conventional water network simulation methods in terms of simulation accuracy and run-time.
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Simple Newsvendor Bounds for Inventory Distribution SystemsLystad, Erik D. 19 December 2006 (has links)
To date, closed form optimal solutions for stocking levels in arborescent multiechelon inventory systems have not been obtained. These problems exhibit the joint difficulties of requiring an allocation policy as well as a stocking policy, and the multidimensional nature of their state space makes dynamic programming formulations impractical. In this dissertation, we introduce procedures that approximate multiechelon networks with sets of single installation problems. We first use this technique to solve for base-stock levels in a distribution network with asymmetric retailers. Second, we use this technique to analyze delayed differentiation production processes and provide guidance as to when the strategy is most warranted. Third, we modify the technique to account for inventory that exhibits perishability and solve for stocking policies for distribution systems when the inventory has a fixed shelf life.
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An evaluation of a pharmacy scheduled I.V. program based on scheduling accuracy, cost, and acceptabilityKopp, Daniel Lee January 1978 (has links)
No description available.
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Incorporating Environmental Impacts into Multi-Objective Optimization of Water Distribution SystemsHERSTEIN, LESLEY 25 August 2009 (has links)
Municipal water distribution system (WDS) expansion is often focused on increasing system capacity with designs that best meet hydraulic requirements at the least cost. Increasing public awareness regarding global warming and environmental degradation is making environmental impact an important factor in decision-making for municipalities. There is thus a growing need to consider environmental impacts alongside cost and hydraulic requirements in the expansion and design of WDSs. As a result, the multiplicity of environmental impacts to consider in WDS expansion can complicate the decisions faced by water utilities. For example, a water utility may wish to consider environmental policy issues such as greenhouse gas emissions, non-renewable resource use, and releases to land, water, and air in WDS expansion planning.
This thesis outlines a multi-objective optimization approach for WDS design and expansion that balances the objectives of capital cost, annual pumping energy use, and environmental impact minimization, while meeting hydraulic constraints. An environmental impact index that aggregates multiple environmental measures was incorporated as an environmental impact objective function in the multi-objective non-dominated sorting genetic algorithm-II (NSGA-II) optimization algorithm. The environmental impact index was developed to reflect stakeholder prioritization of specific environmental policy issues. The evaluation of the environmental impact index and its application to the WDS expansion problem was demonstrated with a water transmission system example. The environmental impact index and multi-objective non-dominated sorting genetic algorithm-II (NSGA-II) optimization algorithm were applied to the “Anytown” network expansion problem. Preliminary results suggest that solutions obtained with the triple-objective capital cost/energy/EI index optimization minimize a number of environmental impact measures while producing results that are comparable in pumping energy use and, in some instances, slightly higher in capital cost when compared to solutions obtained with a double cost/energy optimization in which environmental impact was not considered. / Thesis (Master, Civil Engineering) -- Queen's University, 2009-08-25 16:08:33.636
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Evaluating the Impact of Climate Change Mitigation Strategies on Water Distribution System Design and OptimizationMacLeod, Stephanie Patricia 27 August 2010 (has links)
In response to growing environmental concerns, policy makers in Canada have been developing climate change mitigation strategies that will enable Canada to meet medium and long-term greenhouse gas (GHG) emission reduction targets. The water industry is energy- and carbon-intensive, thus the magnitude and long-term uncertainty of proposed carbon mitigation policies could have implications for water distribution system capital planning decisions that are made today.
The intent of this thesis was to examine the implications of discount rate and carbon price uncertainty on cost, energy use and GHG emissions in the design/optimization of the Amherstview water distribution system in Loyalist Township, Ontario, Canada. A non-dominated sorting genetic algorithm is coupled with the hydraulic solver EPANET2 in a single-objective optimization approach to identify network expansion designs that minimize total cost as the sum of: i) capital cost of installing new and parallel pipes and of cleaning and lining existing pipes; ii) operation cost of electricity for pumping water; and iii) carbon cost levied on electricity used for pumping water. The Amherstview system was optimized for a range of discount rates and carbon prices reflective of possible climate change mitigation strategies in Canada over the next 50 years. The problem formulation framework was developed according to a “real-world” municipal approach to water distribution system design and expansion. Decision variables such as pipe sizes are restricted to “real-world” commercially-available pipe diameters and parameter values are chosen according to engineering judgment and best-estimates. Parameter uncertainty is characterized by sensitivity analysis rather than the more computationally-demanding and data-intensive Monte Carlo simulation method. The impact of pipe material selection on energy use and GHG emissions was investigated for polyvinyl chloride and cement-mortar lined ductile iron pipes. Results from this first-ever study indicate that the discount rate and carbon prices investigated had no significant influence on energy use and GHG emissions in the Amherstview system. Pipe material selection was also found to minimally affect the amount of GHG emitted in the Amherstview system. / Thesis (Master, Civil Engineering) -- Queen's University, 2010-08-26 15:01:27.174
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Optimal Energy Management of Distribution Systems and Industrial Energy Hubs in Smart GridsPaudyal, Sumit January 2012 (has links)
Electric power distribution systems are gradually adopting new advancements in communication, control, measurement, and metering technologies to help realize the evolving concept of Smart Grids. Future distribution systems will facilitate increased and active participation of customers in Demand Side Management activities, with customer load profiles being primarily governed by real-time information such as energy price, emission, and incentive signals from utilities. In such an environment, new mathematical modeling approaches would allow Local Distribution Companies (LDCs) and customers the optimal operation of distribution systems and customer's loads, considering various relevant objectives and constraints.
This thesis presents a mathematical model for optimal and real-time operation of distribution systems. Thus, a three-phase Distribution Optimal Power Flow (DOPF) model is proposed, which incorporates comprehensive and realistic models of relevant distribution system components. A novel optimization objective, which minimizes the energy purchased from the external grid while limiting the number of switching operations of control equipment, is considered. A heuristic method is proposed to solve the DOPF model, which is based on a quadratic penalty approach to reduce the computational burden so as to make the solution process suitable for real-time applications. A Genetic Algorithm based solution method is also implemented to compare and benchmark the performance of the proposed heuristic solution method. The results of applying the DOPF model and the solution methods to two distribution systems, i.e., the IEEE 13-node test feeder and a Hydro One distribution feeder, are discussed. The results demonstrate that the proposed three-phase DOPF model and the heuristic solution method may yield some benefits to the LDCs in real-time optimal operation of distribution systems in the context of Smart Grids.
This work also presents a mathematical model for optimal and real-time control of customer electricity usage, which can be readily integrated by industrial customers into their Energy Hub Management Systems (EHMSs). An Optimal Industrial Load Management (OILM) model is proposed, which minimizes energy costs and/or demand charges, considering comprehensive models of industrial processes, process interdependencies, storage units, process operating constraints, production requirements, and other relevant constraints. The OILM is integrated with the DOPF model to incorporate operating constraints required by the LDC system operator, thus combining voltage optimization with load control for additional benefits. The OILM model is applied to two industrial customers, i.e., a flour mill and a water pumping facility, and the results demonstrate the benefits to the industrial customers and LDCs that can be obtained by deploying the proposed OILM and three-phase DOPF models in EHMSs, in conjunction with Smart Grid technologies.
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Risk Analysis and Adaptive Response Planning for Water Distribution Systems Contamination Emergency ManagementRasekh, Amin 2012 August 1900 (has links)
Drinking water distribution systems (WDSs) hold a particularly critical and strategic position in preserving public health and industrial growth. Despite the ubiquity of this infrastructure, its importance for public health, and increased risk of terrorism, several aspects of emergency management for WDSs remain at an undeveloped stage. A set of methods is developed to analyze the risk and consequences of WDS contamination events and develop emergency response support tools.
Monte Carlo and optimization schemes are developed to evaluate contamination risk of WDSs for generation of critical contamination scenarios. A multicriteria optimization approach is proposed that treats likelihood and consequences as independent risk measures to find an ensemble of uniformly-distributed critical scenarios. This approach provides insight into system risk and potential mitigation options not available under maximum risk or maximum consequences analyses.
Static multiobjective simulation-optimization schemes are developed for generation of optimal response mechanisms for contamination incidents with twoconflicting objectives of minimization of health consequences and impacts on non-consumptive water uses. Performance of contaminant flushing and containment are investigated. Pressure-driven hydraulic analysis is performed to simulate the complicated system hydraulics under pressure-deficit conditions.
Performance of a novel preventive response action ? injection of food-grade dye directly into drinking water ? for mitigation of health impacts as a contamination threat unfolds is explored. The emergency response is formulated as a multiobjective optimization problem for the minimization of risks to life with minimum false warning and cost. A multiobjective optimization scheme is used for the management of contamination events for diverse contaminant agents without interruption of firefighting.
A dynamic modeling scheme is developed that accounts for the time-varying behavior of the system during an emergency. Effects of actions taken by the managers and consumers as well as the changing perceived contaminant source attributes are included in the simulation model to provide a realistic picture of the dynamic environment. A dynamic optimization scheme is coupled with the simulation model to identify and update the optimal response recommendations during the emergency.
Machine learning approaches are employed for real-time characterization of contaminant sources and identification of effective response strategies for a timely and effective response to contamination incidents and threats. In contrast to traditional approaches that perform whole analysis after a contamination event occurs, proposed machine learning methods gain system knowledge in advance and use this extracted information to identify contamination attributes after an incident occurs.
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OPTIMAL LOCATIONS OF BOOSTER STATIONS IN WATER DISTRIBUTION SYSTEMSSUBRAMANIAM, PRATHIBA 03 December 2001 (has links)
No description available.
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DISSOLVED ARSENIC RELEASE FROM DRINKING WATER DISTRIBUTION SYSTEM SOLIDSCOPELAND, RACHEL C. January 2005 (has links)
No description available.
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