Spelling suggestions: "subject:"antagonist""
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On the autonomic control of blood flow and secretion in salivary glands : functional and morphological aspects of muscarinic receptor subtypes in different species /Ryberg, Anders T., January 2007 (has links)
Diss. (sammanfattning) Göteborg : Göteborgs universitet, 2007. / Härtill 4 uppsatser.
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Synthesis of dehydroperloline and of lactam antagonists of (Sd (B-aminobutyric acid (GABA) : a thesis presented for the degree of Doctor of Philosophy in the University of Adelaide /Thach, Duong. January 1976 (has links) (PDF)
Thesis (Ph.D.)--University of Adelaide, Department of Organic Chemistry, 1977. / Includes bibliographical references.
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Molecular basis of estrogen receptor antagonism /Heldring, Nina, January 2006 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2006. / Härtill 4 uppsatser.
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Effects of neuroactive steroids on the recombinant GABAA receptor in Xenopus oocyte /Rahman, Mozibur, January 2007 (has links)
Diss. (sammanfattning) Umeå : Univ., 2007. / Härtill 4 uppsatser.
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High dose rate brachytherapy boost for localized prostate cancer : clinical and patient-reported outcomes/Wahlgren, Thomas, January 2006 (has links)
Diss. (sammanfattning) Stockholm : Karolinska institutet, 2006. / Härtill 4 uppsatser.
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Alterations in responsiveness and mRNA expression of alpha-1 adrenergic receptors in neonatal ventral hippocampus lesioned ratsKamath, Aarthi. January 1900 (has links)
Thesis (M.Sc.). / Written for the Dept. of Neurology and Neurosurgery. Title from title page of PDF (viewed 2008/05/14). Includes bibliographical references.
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Temporal trends in the medical treatment of unstable angina, 1990-1995, and health outcomes associated with beta-blocker and diltiazem treatment of unstable angina /Smith, Nicholas Lannon. January 1997 (has links)
Thesis (Ph. D.)--University of Washington, 1997. / Vita. Includes bibliographical references (leaves [65]-76).
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Beta1-selective adrenoceptor antagonists in chronic non-specific lung diseaseGreefhorst, Aloysius Paulus Maria, January 1900 (has links)
Thesis (doctoral)--Katholieke Universiteit te Nijmegen.
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Synthèse et évaluation de nouveaux squelettes de molécules potentiellement antagonistes du récepteur au CGRP : application à la douleur chronique / Synthesis and biological evaluation of potential CGRP antagonists : application to chronic painKandepedu Hemachandra, Nishanth 27 November 2015 (has links)
Analgésiques opiacés et les antidépresseurs tricycliques (ATC) sont deux grandes classes d'agents thérapeutiques qui sont utilisés pour soulager les symptômes dus au nociception chronique. Mais ces agents chimio thérapeutiques présentent des effets secondaires comme la constipation, dépendance physique plus soulagement de la douleur insuffisante. D'où des complications aggravent la nécessité de concevoir une molécule qui agit sur nouvelle cible en vue de surmonter les effets secondaires causés par la classe dit ci-dessus de médicaments. Pendant ce temps, la distribution du peptide lié au gène de la calcitonine (CGRP), un neuropeptide de 37 acides aminés deux dans le système nerveux central et périphérique et son rôle dans la douleur viscérale a ouvert une nouvelle porte d'entrée pour le traitement de la douleur nociceptive viscérale. Ainsi, l'objectif principal du projet de fusionner propriété antagoniste de CGRP ainsi que la propriété antidépresseur dans une seule molécule, pour fournir un effet de synergie et de traiter les maladies chroniques, inflammatoires et négligées comme le syndrome du côlon irritable (IBS) et la maladie de Crohn. / Opiate analgesics and tricyclic antidepressants (TCAs) are two major classes of therapeutic agents which are used to alleviate symptoms due to chronic nociception. But these chemotherapeutic agents pose side effects like constipation, physical dependence along with insufficient pain relief. Hence these complications aggravate the necessity of designing a molecule which acts on new target in order to overcome the side effects caused by the above said class of drugs. Meanwhile, the distribution of Calcitonin Gene Related Peptide (CGRP), a 37 amino acid neuropeptide both in central and peripheral nervous system and its role in visceral pain has opened up a new gateway for treating visceral nociceptive pain. Thus, the main aim of the project was to merge CGRP antagonist property as well as Antidepressant property in a single molecule, to provide a synergistic effect and to treat Chronic, inflammatory and neglected diseases like Irritable bowel syndrome (IBS) and Crohn’s disease.
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Anticholinergic toxicity in a one-year-old male following ingestion of Lupinus mutabilis seeds: case reportFlores-Pamo, Adrian Ernesto, Pisano, Elinor, Carreazo, Nilton Yhuri 06 November 2017 (has links)
CONTEXT:
The seeds from Lupinus mutabilis Sweet, also called “chocho”, are an important part of the diet in several countries in South America. Prior to consumption, processing is required to remove toxic alkaloids. These alkaloids are known to have pharmacological properties as antiarrhythmics, antimuscarinics and hypoglycemics.
CASE REPORT:
We report a case in which a one-year-old male initially presented with altered mental status and respiratory distress and subsequently developed symptoms of anticholinergic toxicity, after ingesting a large amount of chocho seeds.
CONCLUSION:
In spite of going through a difficult clinical condition, the subject evolved favorably through receiving supportive treatment. The seeds from Lupinus mutabilis provide nutritional benefits when consumed, but people need to know their risks when these seeds are consumed without proper preparation.
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