This thesis used geographic information systems and remote sensing to measure expansion of aquaculture Northwest Mississippi. A feature extraction technique was used to identify aquaculture from satellite imagery. Variations in well water depth were examined in relation to the changes in aquaculture to explore its affects on the Mississippi River Valley Alluvial Aquifer (MRVA) aquifer. A soil moisture index was used to investigate preferential expansion of aquaculture onto soil moisture types. This study found that aquaculture expanded from 66,000 acres in 1984 to 142,000 acres in 2001. Total acreage of individual counties from the Feature Extraction is higher than estimates provided by the Mississippi Agriculture Statistics Service. It was found that aquaculture expansion covered more acres of wet soil classes than dry soil classes and the volumes of expansion onto moist soils depth time series were highly variable across the study area and showed no conclusive relationship to aquaculture expansion.