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Studies of balance in older peopleHill, Keith David Unknown Date (has links) (PDF)
Balance dysfunction and the resultant falls and injuries, loss of confidence, alternations lifestyle and the overall costs are a major problem to older people in Australia. The studies in this thesis investigate discrete but inter-linked aspects of the problems of falls among community dwelling older people, including measurement issues, prediction of fallers, types of dysfunction related to clinical diagnoses, and the effect of multidisciplinary intervention. Preliminary studies of older people from both healthy and clinical samples identified high retest reliability for the dynamic balance tests on the Chattecx Balance System, high retest reliability and concurrent validity for a new clinical test of dynamic standing balance, and high retest reliability and predictive validity for an expanded scale to measure fear of falling. (For complete abstract open document)
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Vnější ekonomická rovnováha České republiky se zaměřením na roli PZI / External Economic Balance of Czech Republic with a Focus on a Role of Foreign Direct InvestmentsKoubková, Marie January 2010 (has links)
The work deals with the structure of the balance of payments, including its compensation process. It also includes an analysis of this statement in the Czech Republic. Given the importance of foreign direct investment in today's economy, which is based on the international division of labor, the work also focuses on the role of FDI in the country.
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Synthèse de dérivés tensioactifs de virginiamycine et étude de leurs propriétés.Nott, Katherine 05 December 2007 (has links)
Nott Katherine (2007). Synthèse de dérivés tensioactifs de virginiamycine et étude de leurs propriétés (Thèse de doctorat). Gembloux, Académie universitaire Wallonie-Europe, Faculté Universitaire des Sciences Agronomiques, 317 p., 66 tabl., 79 fig.
Résumé : Suite à la purification du facteur M1 de la virginiamycine, des dérivés ont été synthétisés et purifiés. Deux types de mono-dérivés ont été obtenus : des esters avec des acides gras (modification de M1 au niveau de lhydroxyle en C-14) et des oximes (liaison chimiosélective) dérivées dacides aminés (réaction avec le carbonyle cétonique en C-16). Des di-dérivés ont également été produits en modifiant simultanément ces deux sites réactionnels avec un acide gras dune part et un aminooxy acétyle acide aminé dautre part. Lidentité des dérivés a été confirmée par un ensemble de techniques spectrales (infrarouge, masse et résonance magnétique nucléaire). Leurs propriétés tensioactives fondamentales ont été étudiées et un criblage de leurs activités antimicrobiennes a été réalisé.
Laugmentation simultanée des caractères hydrophobe et hydrophile de M1 (cas des di-dérivés) est nécessaire pour lui conférer un caractère tensioactif marqué. Les di-dérivés présentent des caractéristiques tensioactives (cinétique dadsorption et formation de micelles) similaires voire supérieures à celles dautres tensioactifs classiques de la littérature et de certains biosurfactants tels que les lipopeptides de Bacillus subtilis. La synthèse de di-dérivés a augmenté la capacité de M1 à pénétrer dans un modèle membranaire. Le rôle favorable de M1 sur certaines propriétés de surface a été mis en évidence par comparaison des propriétés des di-dérivés avec celles de molécules témoins de type amide formées entre un acide gras et un acide aminé.
La gamme de di-dérivés synthétisés a permis de contribuer aux études des relations structure fonction dans le domaine des tensioactifs.
Le criblage des activités antibactériennes des dérivés a montré limportance des fonctions hydroxyle et cétone pour lactivité antibiotique initiale de M1. Les di-dérivés ainsi que les molécules témoins synthétisées présentent une activité vis-à-vis de certaines bactéries et moisissures. Cela pourrait être attribué à la capacité de ces molécules à déstabiliser les membranes de ces microorganismes.
Nott Katherine (2007). Synthesis of surface active derivatives of virginiamycin and study of their properties (PhD thesis in french). Gembloux, Belgium, University Academy Walloon Region-Europe, Gembloux Agricultural University, 317 p., 66 tabl., 79 fig.
Summary : Following the purification of the M1 factor of virginiamycin, derivatives have been synthesised and purified. Two types of mono-derivatives have been obtained : esters with fatty acids (modification of M1 at its C-14 hydroxyl) and oximes (chemoselective ligation) with aminooxylated amino acids (reaction with the ketone carbonyl at C-16). Bis-derivatives have also been produced by simultaneously modifying the two reactive sites with a fatty acid on one side and an aminooxylated amino acid on the other. The identity of each derivative has been confirmed by a combination of spectral techniques (infrared, mass and nuclear magnetic resonance). Their fundamental tensioactive properties have been studied and screening of their activity against microorganisms has been undertaken.
The simultaneous increase of M1s hydrophobic and hydrophilic character (the case of the bis-derivatives) was necessary to render M1 surface active. The bis-derivatives have surface active characteristics (adsorption kinetics and micelle formation) similar or even superior to those of classical surfactants of the literature and of some biosurfactants such as Bacillus subtiliss lipopeptides. The synthesis of the bis-derivatives has enhanced M1s capacity to penetrate a biological membrane model. M1s positive impact on some surface properties has been shown by comparison with amide type molecules obtained by reacting a fatty acid with an amino acid.
The range of the synthesised bis-derivatives has allowed this work to contribute to the studies of the relationships between surfactants structures and their properties.
The screening of the derivatives antibacterial activities has shown the importance of the hydroxyl and ketone groups for M1s initial antibiotic activity. The bis-derivatives and the reference molecules show an activity against some bacteria and fungi. This may be due to their capacity to destabilise the microorganisms membranes.
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Vnější ekonomická rovnováha České republiky / The external economic equilibrium of the Czech republicŠedivý, Ctibor January 2011 (has links)
This thesis focuses on the theoretical conception of the Balance of Payment, its method of adjustment and stress the development of the Czech republic's Balance of Payment in period 2000 -- 2010 via analytical-descriptive approach. It defines its basic terms practical relations within framework of the horizontal and vertical outlook. Thesis's Attention is spread out between status and flow quantity. Thesis is also consist of three boxes that contain a short profile of intertemporal approach to the Common Account, sustainability of investment position and excursion to the essential theories of foreign currency exchange rate that is related to the Balance of payment tight. The end is dedicated to the "traditional" indicators of external equilibrium of the Czech republic in pre-monetary crisis era and in the present.
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