INTRODUÇÃO: O esôfago de Barrett (EB) é uma patologia que aumenta substancialmente o risco de adenocarcinoma esofágico. Os pacientes portadores de EB devem ser seguidos ao longo de toda a vida na tentativa da detecção de neoplasia em estágio precoce. A endoscopia digestiva alta (EDA) é, atualmente, o método de eleição. OBJETIVO: Avaliar a eficácia da cápsula endoscópica do esôfago (CEE) comparada à EDA com cromoscopia com azul de metileno para detecção de lesões suspeitas de neoplasia esofágica, avaliação da extensão e padrão do EB, e identificação da presença de hérnia de hiato; além de comparar a segurança e grau de desconforto dos dois métodos. MÉTODOS: Estudo de casos transversal, realizado em 22 pacientes sabidamente portadores de EB que foram submetidos à fundoplicatura à Nissen há mais de 5 anos. Os pacientes realizaram os exames de CEE e EDA com cromoscopia esofágica por médicos diferentes e desconhecedores dos achados do outro exame. Após a realização dos exames, foi aplicado um questionário onde foi anotado o grau de desconforto do paciente em cada exame e eventuais complicações. Foi avaliado o índice de concordância (kappa) entre os dois métodos para pesquisa de lesões suspeitas de neoplasia esofágica, características do EB e detecção de hérnia hiatal. RESULTADOS: Dezenove pacientes completaram o estudo. A CEE apresentou sensibilidade e valor preditivo negativo de 100% e acurácia de 79% para detecção de lesão suspeita de neoplasia esofágica e concordância razoável com EDA (kappa = 0,27). A acurácia da CEE para avaliação da extensão do EB foi de 89% e concordância moderada (kappa = 0,60) com EDA. A acurácia da CEE para avaliação de EB digitiforme, circunferencial e misto foram, respectivamente, 74%, 79% e 74% com concordância moderada nos casos de EB circunferencial e misto e não significante no EB digitiforme. Quanto à detecção de hérnia de hiato a CEE apresentou sensibilidade de 43% e acurácia de 74%, com concordância razoável (kappa = 0,38) com EDA. Não houve diferença estatística de desconforto entre os exames e não houve complicação em ambos os métodos endoscópicos. CONCLUSÕES: A CEE mostrou-se um bom método de detecção de lesões suspeitas de neoplasia esofágica. Quanto a avaliação da extensão e padrão do EB, a CEE apresentou resultados razoáveis, quando comparada à EDA com cromoscopia esofágica. A CEE apresentou resultados insatisfatórios quanto à detecção de hérnia hiatal. Não houve diferença significativa de desconforto entre CEE e EDA. Os dois métodos mostraram-se seguros / INTRODUCTION: Barrett\'s esophagus (BE) is a condition that substantially increases the risk of esophageal adenocarcinoma. Patients with BE should be followed throughout life in an attempt to detect cancer at an early stage. Upper gastrointestinal endoscopy (GIE) is currently the method of choice. OBJECTIVE: To evaluate the efficacy of esophageal capsule endoscopy (ECE) compared to methylene blue (MB) chromoendoscopy for detection of suspicious lesions of esophageal cancer, evaluation of extent and pattern of BE, and identifying the presence of hiatal hernia, in addition to compare the safety and patients discomfort of the two methods. METHODS: Transverse study, conducted on 22 Barretts patients submitted to Nissen fundoplication with more than five years follow-up. Patients underwent examinations of ECE and MB chromoendoscopy by different physicians blinds to each procedures. After the exams, patients discomfort and possible complications that occurred in each method were recorded. It was evaluated the concordance index between the two methods for detection of suspicious lesions of esophageal cancer, extent and pattern of BE and hiatal hernia detection. RESULTS: Nineteen patients completed the study. The ECE sensitivity, negative predictive value and accuracy were, respectively, 100%, 100% and 79% for detecting suspicious lesion of esophageal cancer and had reasonable agreement with MB chromoendoscopy (kappa = 0.27). The ECE accuracy for assessing the extent of BE was 89% and had moderate agreement (kappa = 0.60) with MB chromoendoscopy. The accuracy of the ECE for evaluation of finger-like, circumferential, and mixed BE were respectively 74%, 79% and 74%, and moderate agreement in cases of circumferencial and mixed BE and not significant agreement for finger-like BE. ECE sensitivity and accuracy for detecting hiatal hernia were, respectively, 43 % and 74%, and fair agreement (kappa = 0.38) with MB chromoendoscopy. There was no statistical difference between the discomfort of examinations and there was no complication in both endoscopic methods. CONCLUSIONS: The ECE has proved to be a good method for detecting suspicious lesions of esophageal cancer. As the evaluation of the extent and pattern of BE, the ECE had reasonable results, when compared to MB chromoendoscopy. The ECE had unsatisfactory results regarding the detection of hiatal hernia. There was no significant difference in discomfort between the ECE and GIE. Both methods proved to be safe

Thesis (Ph. D.)--University of Washington, 2006. / Vita. Includes bibliographical references (leaves 44-53).

Thesis (M.P.H.)--University of Texas Health Science Center at Houston, School of Public Health, 2008. / Source: Masters Abstracts International, Volume: 46-06, page: 3259. Adviser: Charles E. Ford. Includes bibliographical references.

INTRODUÇÃO: O esôfago de Barrett (EB) é uma patologia que aumenta substancialmente o risco de adenocarcinoma esofágico. Os pacientes portadores de EB devem ser seguidos ao longo de toda a vida na tentativa da detecção de neoplasia em estágio precoce. A endoscopia digestiva alta (EDA) é, atualmente, o método de eleição. OBJETIVO: Avaliar a eficácia da cápsula endoscópica do esôfago (CEE) comparada à EDA com cromoscopia com azul de metileno para detecção de lesões suspeitas de neoplasia esofágica, avaliação da extensão e padrão do EB, e identificação da presença de hérnia de hiato; além de comparar a segurança e grau de desconforto dos dois métodos. MÉTODOS: Estudo de casos transversal, realizado em 22 pacientes sabidamente portadores de EB que foram submetidos à fundoplicatura à Nissen há mais de 5 anos. Os pacientes realizaram os exames de CEE e EDA com cromoscopia esofágica por médicos diferentes e desconhecedores dos achados do outro exame. Após a realização dos exames, foi aplicado um questionário onde foi anotado o grau de desconforto do paciente em cada exame e eventuais complicações. Foi avaliado o índice de concordância (kappa) entre os dois métodos para pesquisa de lesões suspeitas de neoplasia esofágica, características do EB e detecção de hérnia hiatal. RESULTADOS: Dezenove pacientes completaram o estudo. A CEE apresentou sensibilidade e valor preditivo negativo de 100% e acurácia de 79% para detecção de lesão suspeita de neoplasia esofágica e concordância razoável com EDA (kappa = 0,27). A acurácia da CEE para avaliação da extensão do EB foi de 89% e concordância moderada (kappa = 0,60) com EDA. A acurácia da CEE para avaliação de EB digitiforme, circunferencial e misto foram, respectivamente, 74%, 79% e 74% com concordância moderada nos casos de EB circunferencial e misto e não significante no EB digitiforme. Quanto à detecção de hérnia de hiato a CEE apresentou sensibilidade de 43% e acurácia de 74%, com concordância razoável (kappa = 0,38) com EDA. Não houve diferença estatística de desconforto entre os exames e não houve complicação em ambos os métodos endoscópicos. CONCLUSÕES: A CEE mostrou-se um bom método de detecção de lesões suspeitas de neoplasia esofágica. Quanto a avaliação da extensão e padrão do EB, a CEE apresentou resultados razoáveis, quando comparada à EDA com cromoscopia esofágica. A CEE apresentou resultados insatisfatórios quanto à detecção de hérnia hiatal. Não houve diferença significativa de desconforto entre CEE e EDA. Os dois métodos mostraram-se seguros / INTRODUCTION: Barrett\'s esophagus (BE) is a condition that substantially increases the risk of esophageal adenocarcinoma. Patients with BE should be followed throughout life in an attempt to detect cancer at an early stage. Upper gastrointestinal endoscopy (GIE) is currently the method of choice. OBJECTIVE: To evaluate the efficacy of esophageal capsule endoscopy (ECE) compared to methylene blue (MB) chromoendoscopy for detection of suspicious lesions of esophageal cancer, evaluation of extent and pattern of BE, and identifying the presence of hiatal hernia, in addition to compare the safety and patients discomfort of the two methods. METHODS: Transverse study, conducted on 22 Barretts patients submitted to Nissen fundoplication with more than five years follow-up. Patients underwent examinations of ECE and MB chromoendoscopy by different physicians blinds to each procedures. After the exams, patients discomfort and possible complications that occurred in each method were recorded. It was evaluated the concordance index between the two methods for detection of suspicious lesions of esophageal cancer, extent and pattern of BE and hiatal hernia detection. RESULTS: Nineteen patients completed the study. The ECE sensitivity, negative predictive value and accuracy were, respectively, 100%, 100% and 79% for detecting suspicious lesion of esophageal cancer and had reasonable agreement with MB chromoendoscopy (kappa = 0.27). The ECE accuracy for assessing the extent of BE was 89% and had moderate agreement (kappa = 0.60) with MB chromoendoscopy. The accuracy of the ECE for evaluation of finger-like, circumferential, and mixed BE were respectively 74%, 79% and 74%, and moderate agreement in cases of circumferencial and mixed BE and not significant agreement for finger-like BE. ECE sensitivity and accuracy for detecting hiatal hernia were, respectively, 43 % and 74%, and fair agreement (kappa = 0.38) with MB chromoendoscopy. There was no statistical difference between the discomfort of examinations and there was no complication in both endoscopic methods. CONCLUSIONS: The ECE has proved to be a good method for detecting suspicious lesions of esophageal cancer. As the evaluation of the extent and pattern of BE, the ECE had reasonable results, when compared to MB chromoendoscopy. The ECE had unsatisfactory results regarding the detection of hiatal hernia. There was no significant difference in discomfort between the ECE and GIE. Both methods proved to be safe

No description available.

Because of its importance in the history of the verse novel and the history of women’s writing, Elizabeth Barrett Browning’s Aurora Leigh (1856) has overshadowed the works of other female verse novelists in Victorian studies scholarship. By focusing on non-canonical works by four understudied women poets writing in the late nineteenth century— Augusta Webster’s “Lota” (1867), Violet Fane’s Denzil Place: A Story in Verse (1875), Emily Pfeiffer’s The Rhyme of the Lady of the Rock, and How It Grew (1884), and Emily Hickey’s “Michael Villiers, Idealist” (1891)—this dissertation expands our understanding of both women’s poetry and the verse novel in the Victorian period. It demonstrates that the genre was taken up in multiple ways after Aurora Leigh by women poets who, like EBB, addressed urgent and controversial social and political issues—such as parliamentary enfranchisement, adultery, marital rape, political sovereignty and land use in the Scottish Highlands, as well as socialism and the Irish Question— through inventive and complex generic combinations. This dissertation does not outline a teleological development of genre but, rather, recovers works through case studies that offer microhistories of verse novels at particular historical moments in order to expand the canon and definition of the Victorian verse novel. / Graduate / 2020-04-25

Background: Research today highlights the importance of values alignment, but all of the research has been conducted on manufacturing companies. We found it interesting to investigate if the same theories are applicable to the knowledge-intense service sector, such as consultancy firms. Furthermore, research has identified a set of key attributes of successful teamwork, which we find closely related to values alignment. Despite this, we found no previous research within this area. Purpose: This study investigates the connections between values alignment and teamwork at a consultancy firm. Method: Our research was conducted as a case study at the department of Management at a consultancy firm. A survey, based on Barrett’s (2008) Seven Level Consciousness, and Cultural Values Assessment models, was carried out. However, we have modified the model to fit Swedish work-related values. We conducted pre-survey, and follow-up survey interviews with employees at the consultancy firm, as well as an interview with a former employee. This triangulation of information gathering techniques allowed us to ensure the validity of our study. Conclusion: We found a set of four clear relations between values alignment and, what previous research has identified as, key success factors of successful teamwork. Commitment, guidance in decision making, quality of outcome and reduced interpersonal conflicts are all outcomes of values alignment, and they are in different ways connected to one or several of commitment to success and shared goals, commitment to team processes and accountability, interpersonal skills, open communication and feedback or interdependencies. / Bakgrund: Dagens forskning belyser vikten av att ha en gemensam värdegrund, men så vitt vi kan se sträcker sig forskningen till att enbart involvera tillverkningsföretag. Vi tyckte att bristen på forskning inom kunskapsintensiva serviceföretag, så som konsultföretag, var intrigerande och bestämde oss för att undersöka huruvida befintliga teorier är applicerbara även på den här sektorn. Forskning har även identifierat ett antal faktorer som kännetecknar framgångsrikt teamwork, vi anser att dessa faktorer är kopplade till att ha en gemensam värdegrund. Trots detta har vi inte hittat någon tidigare forskning inom det här området. Syfte: Den här uppsatsen undersöker sambandet mellan att ha en gemensam värdegrund och teamwork på ett konsultföretag. Metod: Den här undersökningen är genomförd som en fall studie på Mana-gementavdelningen på ett konsultföretag. Vi sände ut en enkät till de anställda, som byggde på Barretts (2008) Seven Level Consciousness och Cultural Values Assessment modeller. Vi har dock anpassat enkäten till att stämma överens med svenska arbetsrelaterade värderingar. Förutom detta genomförde vi intervjuer innan enkäten skickades ut, samt uppföljningsintervjuer. Utöver de intervjuerna, gjorde vi även en intervju med en före detta anställd på företaget. Den här trianguleringen gjorde det möjligt för oss att försäkra validiteten för vår undersökning. Slutsats: Vi fann fyra tydliga kopplingar mellan fördelarna med att ha gemensam värdegrund, och vad som genom tidigare forskning har identifierats som framgångsfaktorer för teamwork. Engagemang, stöd för beslutsfattande, kvalitet samt en minskning av sociala konflikter är alla effekter av att ha en gemensam värdegrund. Dessa är på olika sätt relaterade till en eller flera av följande; engagemang i framgång och delade mål, engagemang till team processer och ansvarsskyl-dighet, social kompetens, öppen kommunikation och feedback eller ömsesidigt beroende.

<p><strong>Background: </strong>Research today highlights the importance of values alignment, but all of the research has been conducted on manufacturing companies. We found it interesting to investigate if the same theories are applicable to the knowledge-intense service sector, such as consultancy firms. Furthermore, research has identified a set of key attributes of successful teamwork, which we find closely related to values alignment. Despite this, we found no previous research within this area.</p><p><strong>Purpose:</strong> This study investigates the connections between values alignment and teamwork at a consultancy firm.</p><p><strong>Method:</strong> Our research was conducted as a case study at the department of Management at a consultancy firm. A survey, based on Barrett’s (2008) Seven Level Consciousness, and Cultural Values Assessment models, was carried out. However, we have modified the model to fit Swedish work-related values. We conducted pre-survey, and follow-up survey interviews with employees at the consultancy firm, as well as an interview with a former employee. This triangulation of information gathering techniques allowed us to ensure the validity of our study.</p><p><strong>Conclusion:</strong> We found a set of four clear relations between values alignment and, what previous research has identified as, key success factors of successful teamwork. Commitment, guidance in decision making, quality of outcome and reduced interpersonal conflicts are all outcomes of values alignment, and they are in different ways connected to one or several of <em>commitment to success and shared goals, commitment to team processes and accountability, interpersonal skills, open communication and feedback or <em>interdependencies. </em></em></p><p> </p><p> </p><p> </p> / <p><strong>Bakgrund</strong><strong>:</strong> Dagens forskning belyser vikten av att ha en gemensam värdegrund, men så vitt vi kan se sträcker sig forskningen till att enbart involvera tillverkningsföretag. Vi tyckte att bristen på forskning inom kunskapsintensiva serviceföretag, så som konsultföretag, var intrigerande och bestämde oss för att undersöka huruvida befintliga teorier är applicerbara även på den här sektorn. Forskning har även identifierat ett antal faktorer som kännetecknar framgångsrikt teamwork, vi anser att dessa faktorer är kopplade till att ha en gemensam värdegrund. Trots detta har vi inte hittat någon tidigare forskning inom det här området.</p><p><strong>Syfte</strong><strong>:</strong> Den här uppsatsen undersöker sambandet mellan att ha en gemensam värdegrund och teamwork på ett konsultföretag.</p><p><strong>Metod:</strong> Den här undersökningen är genomförd som en fall studie på Mana-gementavdelningen på ett konsultföretag. Vi sände ut en enkät till de anställda, som byggde på Barretts (2008) Seven Level Consciousness och Cultural Values Assessment modeller. Vi har dock anpassat enkäten till att stämma överens med svenska arbetsrelaterade värderingar. Förutom detta genomförde vi intervjuer innan enkäten skickades ut, samt uppföljningsintervjuer. Utöver de intervjuerna, gjorde vi även en intervju med en före detta anställd på företaget. Den här trianguleringen gjorde det möjligt för oss att försäkra validiteten för vår undersökning.</p><p><strong>Slutsats:</strong> Vi fann fyra tydliga kopplingar mellan fördelarna med att ha gemensam värdegrund, och vad som genom tidigare forskning har identifierats som framgångsfaktorer för teamwork. Engagemang, stöd för beslutsfattande, kvalitet samt en minskning av sociala konflikter är alla effekter av att ha en gemensam värdegrund. Dessa är på olika sätt relaterade till en eller flera av följande; <em>engagemang i framgång och delade mål, engagemang till team processer och ansvarsskyl-dighet, social kompetens, öppen kommunikation och feedback eller <em>ömsesidigt beroende. </em></em></p><p> </p>

This dissertation critically examines why mid-Victorian fiction often dismisses or complicates monetary transactions and monetary charity, even as it negatively portrays differences in social status and wealth. I argue that the novel uses representations of failed charity to reconstruct, however briefly, a non- monetary and non-economic source of value. Further, I examine how the novel uses techniques of both genre and style to predict, form, and critique alternate, non-economic, social models. While tension surrounding the practice of charity arises in the late eighteenth century, the increasing dominance of political economy in public discourse forced Victorian literature to take a strong stance, for reasons of both ethics and genre. This stance is complicated by the eighteenth-century legacy that sees charity as a kind of luxury. If giving to the poor makes us feel good, this logic suggests, surely it isn’t moral. Thus, while much eighteenth- and nineteenth-century literature remains dedicated to the ethics of charity, the practice becomes immensely complex. By discussing the works of Tobias Smollett, Charles Dickens, Elizabeth Barrett Browning, and George Eliot, this project exposes a wide variety of responses to this deep cultural anxiety. These authors are, ultimately, strongly invested in redefining the meaning of benevolence as a valid form of social action by moving that benevolence away from monetary gifts and toward abstractly correct moral feelings, though their individual solutions vary widely. / text

Thesis (Ph. D.)--State University of New York at Binghamton, Department of English, 2007. / Includes bibliographical references.