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Rapid stereoselective access to the tetracyclic core of puupehenone and related sponge metabolites using metal-free radical cyclisations of cyclohexenyl-substituted 3-bromochroman-4-ones.Pritchard, R.P., Sheldrake, Helen M., Taylor, I.Z., Wallace, T.W. 23 June 2008 (has links)
No / The tetracyclic nucleus of puupehenone, 15-oxopuupehenol and other sesquiterpene¿phenol natural
products can be assembled stereoselectively in three steps, the last of these being the 6-endo-trig cyclisation
of an alpha-keto radical generated from a substituted 2-(2-cyclohexenyl)ethyl 3-bromo-4-chromanone under metal-free conditions. / EPSRC
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