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xii, 197 leaves : ill. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (Ph.D.1972) from the Dept. of Entomology, University of Adelaide

Thesis (Ph.D. 1972) from the Dept. of Entomology, University of Adelaide.

Thesis (MMedVet. (Chir.))--University of Pretoria, 2007. / Includes bibliographical references.

Some of the factors that influence the blood reducing sugar level in the black-tailed deer Odeeoileus hemionus columbianus (Richardson) (Vancouver Island genotype), have been investigated. The distribution of reducing sugar in the blood of these animals was also examined. It was found that: feed intake during the hour preceeding blood letting, short periods of fast, nature of the feed, and sex of the animal apparently have no effect on the level of blood reducing sugar in deer. Blood samples taken in the evening generally had a higher reducing sugar level than those taken earlier in the day. The means used to restrain the animals during the blood letting procedure was also found to have a marked influence on the level of blood reducing sugar. Deer restrained by physical force exhibited significantly higher and more variable blood sugar levels than those immobilized with succinylcholine. The length of time required to draw a blood sample from an animal also influenced the blood sugar level. The longer the time to let a sample, the higher the blood sugar level in the sample. The results indicate that the degree of excitement, fear, and pain experienced by the animals preceeding and during the blood letting procedure was the principal cause of variability found in the level of blood reducing sugar. No reducing sugar could be detected in the erythrocytes of these deer. / Science, Faculty of / Zoology, Department of / Graduate

In an attempt to find out whether decreased blood sugar level is associated with impaired cognitive function, adverse emotional changes, or somatic symptoms, 36 subjects who believed or suspected that they had hypoglycemia were given 5-hour glucose tolerance tests (GTTs). After each of the nine blood samples taken during the GTT, the subject's mood, performance on the Serial Sevens Test (SST), and somatic symptom reports were recorded. The subjects reported significantly more negative affect after glucose nadir (the lowest level of blood sugar reached) than before nadir, and endorsed more somatic symptoms after nadir than before nadir. SST performance deteriorated at glucose nadir. All of these effects were more pronounced for subjects with high hypoglycemic index scores than for subjects with low index scores. The index is calculated from the speed and magnitude of the decrease in blood sugar, and the absolute value of the nadir. The impairment in SST performance was greater for subjects who showed rapid decreases in blood sugar than for subjects who showed slow decreases. Dividing subjects by high and low nadirs, large and small magnitudes of decrease, and by large and small decreases below fasting level, did not reveal any differences in symptomatology. It is concluded that changes in mood, reports of somatic symptoms, and inferior performance on a mental arithmetic task are associated with lowered blood sugar levels, especially in subjects with high hypoglycemic index scores. / Arts, Faculty of / Psychology, Department of / Graduate

In May 1992, Banting and Best, working in the Physiology Department of the University of Toronto, obtained the first active extracts from pancreas. The credit for the preparation of such extracts capable of effecting a lowering of the blood and urinary sugar, and serviceable in mitigating the symptoms of experimental diabetes in animals, and o human diabetes, therefore, belongs to these two workers, to Waoleod and Collip. Improvements in the methods of extraction and purification of insulin followed quickly. Accompanying this were the investigations of the physiological, chemical and physical properties of the hormone. Since that time a mass of evidence relating to the above and produce by a host of workers has accumulated.

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published_or_final_version / abstract / Electrical and Electronic Engineering / Master / Master of Philosophy

published_or_final_version / abstract / toc / Zoology / Master / Master of Philosophy