Thesis (Ph.D.)--University of Delaware, 2007. / Principal faculty advisor: Robert Gilbert, Dept. of Mathematical Sciences. Includes bibliographical references.

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Chow, Dick Ho Kiu. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2010. / Includes bibliographical references (leaves 93-103). / Abstracts in English and Chinese. / Abstract --- p.ii / Publications --- p.vii / Acknowledgement --- p.viii / Table of Contents --- p.x / List of Figures --- p.xiv / List of Tables --- p.xv / List of Abbreviations --- p.xvii / Chapter 1 --- Introduction --- p.1 / Chapter 1.1 --- Bone and its Cellular Components --- p.1 / Chapter 1.1.1 --- Cellular Components of Bone --- p.1 / Chapter 1.1.2 --- Macroscopic Structure --- p.4 / Chapter 1.1.3 --- Microscopic Structure --- p.4 / Chapter 1.2 --- Fracture Healing --- p.5 / Chapter 1.2.1 --- Inflammation --- p.6 / Chapter 1.2.2 --- Soft Callus Formation --- p.6 / Chapter 1.2.3 --- Hard Callus Formation --- p.7 / Chapter 1.2.4 --- Bone Remodeling --- p.7 / Chapter 1.3 --- Low Magnitude High Frequency Vibration (LMHFV) Stimulation --- p.7 / Chapter 1.3.1 --- Mechanical Stimulation --- p.10 / Chapter 1.3.2 --- Effect of LMHFV on Bone --- p.12 / Chapter 1.4 --- Osteoporosis and Osteoporotic Fractures --- p.16 / Chapter 1.4.1 --- Epidemiology of Osteoporotic Fracture --- p.17 / Chapter 1.4.2 --- Pathophysiology --- p.17 / Chapter 1.4.3 --- Osteoporotic Fracture Healing --- p.20 / Chapter 1.5 --- Bisphosphonate --- p.23 / Chapter 1.5.1 --- Background --- p.23 / Chapter 1.5.2 --- Mechanism of Action --- p.24 / Chapter 1.5.3 --- U sage of Bisphosphonate --- p.25 / Chapter 1.5.4 --- Bisphosphonate Effects on Fracture Healing --- p.27 / Chapter 1.6 --- Hypothesis --- p.27 / Chapter 1.7 --- Study Plan --- p.28 / Chapter 1.7.1 --- Objectives --- p.28 / Chapter 2 --- Method --- p.29 / Chapter 2.1 --- Ovariectomized Rat Femoral Fracture Model --- p.29 / Chapter 2.1.1 --- Ovariectomized Rat Model. --- p.29 / Chapter 2.1.2 --- Closed Femoral Fracture --- p.31 / Chapter 2.2 --- Study Design --- p.32 / Chapter 2.3 --- LMHFV Treatment Protocol --- p.32 / Chapter 2.4 --- Bisphosphonate Treatment Protocol --- p.35 / Chapter 2.4.1 --- Pharmacological Parameters --- p.35 / Chapter 2.4.2 --- Ibandronate Injection Solution Preparation --- p.37 / Chapter 2.4.3 --- Injection --- p.37 / Chapter 2.5 --- Fluorochrome Labeling --- p.38 / Chapter 2.5.1 --- Fluorochrome Preparation --- p.38 / Chapter 2.5.2 --- Injection --- p.38 / Chapter 2.6 --- Assessments --- p.39 / Chapter 2.6.1 --- Radiographic Analysis --- p.39 / Chapter 2.6.2 --- uCT Analysis --- p.40 / Chapter 2.6.3 --- Undecalcified Histology --- p.43 / Chapter 2.6.4 --- ELISA Analysis on Bone Markers --- p.47 / Chapter 2.7 --- Statistical Analysis --- p.50 / Chapter 3 --- Results --- p.51 / Chapter 3.1 --- Radiographic Analysis --- p.52 / Chapter 3.1.1 --- Callus Bridging Rate --- p.52 / Chapter 3.1.2 --- Callus Width and Area --- p.52 / Chapter 3.2 --- uCT Analysis --- p.55 / Chapter 3.3 --- Histomorphometric Analysis --- p.61 / Chapter 3.3.1 --- Bone Mineralization Rate --- p.61 / Chapter 3.4 --- Bone Markers Analysis --- p.64 / Chapter 3.4.1 --- Osteocalcin --- p.64 / Chapter 3.4.2 --- TRAP5b --- p.64 / Chapter 3.4.3 --- Summary --- p.67 / Chapter 4 --- Discussion --- p.69 / Chapter 4.1 --- LMHFV Enhanced Bone Remodeling --- p.69 / Chapter 4.1.1 --- LMHFV Reversed Bis Inhibition on Bone Remodeling --- p.70 / Chapter 4.1.2 --- LMHFV Effect on Osteoclastic Resorption During Bone Re-modeling --- p.71 / Chapter 4.2 --- Enhanced Fracture Healing by LMHFV --- p.72 / Chapter 4.2.1 --- Acceleration of Fracture Healing by LMHFV --- p.72 / Chapter 4.2.2 --- LMHFV Inhibits Osteoclast Activity in the Early Phase of Healing --- p.73 / Chapter 4.2.3 --- LMHFV Stimulates Osteoblast Activity in the Early Phase of Healing --- p.74 / Chapter 4.3 --- Bis Delays Fracture Healing --- p.75 / Chapter 4.4 --- Experimental Design --- p.78 / Chapter 4.4.1 --- Inhibition Study --- p.78 / Chapter 4.4.2 --- Bisphosphonate Injection Protocol --- p.79 / Chapter 4.4.3 --- Individual Analysis of Bone Formation and Resorption . --- p.81 / Chapter 4.5 --- Clinical Implications --- p.84 / Chapter 4.5.1 --- LMHFV Enhanced Remodeling --- p.84 / Chapter 4.5.2 --- Bisphosphonate Delayed Remodeling --- p.85 / Chapter 4.6 --- Limitations --- p.85 / Chapter 4.6.1 --- Measurement of Bone Resorption --- p.85 / Chapter 4.6.2 --- Osteoporotic Fracture Model --- p.86 / Chapter 4.6.3 --- Inhibition of Bone Remodeling --- p.87 / Chapter 4.7 --- Future Studies --- p.88 / Chapter 4.7.1 --- LMHFV Effect on Osteoclast in vitro --- p.88 / Chapter 4.7.2 --- Biomechanics of Fracture Callus --- p.89 / Chapter 4.7.3 --- LMHFV Effect on Leptin- Adrenergic Pathway --- p.89 / Chapter 5 --- Conclusion --- p.91 / Bibliography --- p.93

Thesis (Ph. D.)--School of Dentistry. University of Missouri--Kansas City, 2003. / "A dissertation in oral biology and molecular biology and biochemistry." Advisor: Jian Q. Feng. Typescript. Vita. Title from "catalog record" of the print edition Description based on contents viewed July 16, 2008. Includes bibliographical references (leaves 109-121). Online version of the print edition.

Thesis (Ph. D.)--Rensselaer Polytechnic Institute, Troy, New York, 1992. / eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (p. 184-200).

Thesis (Ph. D.)--Rensselaer Polytechnic Institute, Troy, New York, 1992. / Includes bibliographical references (p. 184-200).

Thesis (M.S.)--West Virginia University, 2005. / Title from document title page. Document formatted into pages; contains vii, 82 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 60-82).

Thesis (M.S.)--California Polytechnic State University, 2010. / Title from PDF title page; viewed on May 15, 2010. Major professor: Scott Hazelwood, Ph.D. "Presented to the faculty of California Polytechnic State University, San Luis Obispo." "In partial fulfillment of the requirements for the degree [of] Master of Science in Engineering, with a Specialization in Biomedical Engineering." "April 2010." Includes bibliographical references (p. 73-78).

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Thesis (Ph. D.)--University of Missouri-Columbia, 1998. / Typescript. Vita. Includes bibliographical references (leaves 158-182). Also available on the Internet.