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Emerging topic detection algorithms have the potential to assist researchers in maintaining awareness of current trends in biomedical fields--a feat not easily achieved with existing methods. Though topic detection algorithms for news-cycles exist, several aspects of this particular area make applying them directly to scientific literature problematic. This dissertation offers a framework for emerging topic detection in biomedicine. The framework includes a novel set of weightings based on the historical importance of each topic identified. Features such as journal impact factor and funding data are used to develop a fitness score to identify which topics are likely to burst in the future. Characterization of bursts over an extended planning horizon by discipline was performed to understand what a typical burst trend looks like in this space to better understand how to identify important or emerging trends. Cluster analysis was used to create an overlapping hierarchical structure of scientific literature at the discipline level. This allows for granularity adjustment (e.g. discipline level or research area level) in emerging topic detection for different users. Using cluster analysis allows for the identification of terms that may not be included in annotated taxonomies, as they are new or not considered as relevant at the time the taxonomy was last updated. Weighting topics by historical frequency allows for better identification of bursts that are associated with less well-known areas, and therefore more surprising. The fitness score allows for the early identification of bursty terms. This framework will benefit policy makers, clinicians and researchers.

The new social media sites - blogs, micro-blogs, and social networking sites, among others - are gaining considerable momentum to facilitate collaboration and social interactions in general. These sites provide a tremendous asset for understanding social phenomena by providing a wide availability of novel data sources. Recent estimates suggest that social media sites are responsible for as much as one third of new Web content, in the forms of social networks, comments, trackbacks, advertisements, tags, etc. One critical and immediate challenge facing the MIS researchers then becomes - how to effectively utilize this huge wealth of social media data, to facilitate business knowledge discovery and decision making.Among these available data sources, social networks constitute the backbone of almost all social media sites. These network structures provide a rich description of the social scenes and contexts, which is helpful for us to address the above challenge. In this dissertation, I have primarily employed the probabilistic network models, to study various social network related problems arose from the use of social media services. In Chapter 2 and Chapter 3, I studied how information overload can affect the efficiency of information diffusion in online social networks (Delicious.com and Digg.com). Novel diffusion model were proposed to model the observed information overload. The models and their extensions are thoroughly evaluated by solving the Influence Maximization problem related to information diffusion and viral marketing applications. In Chapter 4, I studied the information overload in a micro-blogging application (Twitter.com) using a design science methodology. A content recommendation framework was proposed to help micro-blogging users to efficiently identify quality emergency news feeds. Chapter 5 presents a novel burst detection algorithm concerning identifying and analyzing correlated burst patterns by considering multiple inputs (data streams) that co-evolve over time. The algorithm was later used for discovering burst keywords/tag pairs from online social communities, which are strong indicators of emerging or changing user interests.Chapter 6 concludes this dissertation by highlighting major research contributions and future directions.

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This thesis presents a research work on the development of new methodology for near-real-time detection and localisation of pipe bursts in a Water Distribution System (WDS) at the District Meters Area (DMA) level. The methodology makes use of online hydraulic model coupled with a demand forecasting methodology and several statistical techniques to process the hydraulic meters data (i.e., flows and pressures) coming from the field at regular time intervals (i.e. every 15 minutes). Once the detection part of the methodology identifies a potential burst occurrence in a system it raises an alarm. This is followed by the application of the burst localisation methodology to approximately locate the event within the District Metered Area (DMA). The online hydraulic model is based on data assimilation methodology coupled with a short-term Water Demand Forecasting Model (WDFM) based on Multi-Linear Regression. Three data assimilation methods were tested in the thesis, namely the iterative Kalman Filter method, the Ensemble Kalman Filter method and the Particle Filter method. The iterative Kalman Filter (i-KF) method was eventually chosen for the online hydraulic model based on the best overall trade-off between water system state prediction accuracy and computational efficiency. The online hydraulic model created this way was coupled with the Statistical Process Control (SPC) technique and a newly developed burst detection metric based on the moving average residuals between the predicted and observed hydraulic states (flows/pressures). Two new SPC-based charts with associated generic set of control rules for analysing burst detection metric values over consecutive time steps were introduced to raise burst alarms in a reliable and timely fashion. The SPC rules and relevant thresholds were determined offline by performing appropriate statistical analysis of residuals. The above was followed by the development of the new methodology for online burst localisation. The methodology integrates the information on burst detection metric values obtained during the detection stage with the new sensitivity matrix developed offline and hydraulic model runs used to simulate potential bursts to identify the most likely burst location in the pipe network. A new data algorithm for estimating the ‘normal’ DMA demand and burst flow during the burst period is developed and used for localisation. A new data algorithm for statistical analysis of flow and pressure data was also developed and used to determine the approximate burst area by producing a list of top ten suspected burst location nodes. The above novel methodologies for burst detection and localisation were applied to two real-life District Metred Areas in the United Kingdom (UK) with artificially generated flow and pressure observations and assumed bursts. The results obtained this way show that the developed methodology detects pipe bursts in a reliable and timely fashion, provides good estimate of a burst flow and accurately approximately locates the burst within a DMA. In addition, the results obtained show the potential of the methodology described here for online burst detection and localisation in assisting Water Companies (WCs) to conserve water, save energy and money. It can also enhance the UK WCs’ profile customer satisfaction, improve operational efficiency and improve the OFWAT’s Service Incentive Mechanism (SIM) scores.