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Identification and characterization of a peptide toxin inhibitor of ClC-2 chloride channelsThompson, Christopher Hal. January 2008 (has links)
Thesis (Ph.D)--Biology, Georgia Institute of Technology, 2009. / Committee Chair: McCarty, Nael; Committee Co-Chair: Harvey, Stephen; Committee Member: Hartzell, Criss; Committee Member: Kubanek, Julia; Committee Member: Lee, Robert. Part of the SMARTech Electronic Thesis and Dissertation Collection.
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Chloride channel in glioma cell invasionSin, Sai-lung, Steven., 冼世隆. January 2008 (has links)
published_or_final_version / Surgery / Master / Master of Philosophy
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Alternate channel therapy for the pancreatic disease of Cystic FibrosisAdair, Jeanette January 2001 (has links)
No description available.
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Structure function analysis of glutamate gated chloride channelsStarc, Tanja January 2003 (has links)
Glutamate-gated chloride channels (GluCl) belong to then icotinic ligand-gated ion channel family and are thus assumed to be heteropentamers. Each subunit contains a large extracellular N-terminal domain, four transmembrane domains (TM1--TM4), and an extracellular C terminal. Caenorhabditis elegans expresses various GluCl channels formed by alpha1, alpha2, alpha3, alpha4 and beta subunits. The best understood GluCl channel is expressed in pharyngeal muscle cells where it mediates response to the M3 motor neuron. alpha2 forms this channel, probably in association with beta. The alpha2 mutant lacks M3 neurotransmission which can be rescued by pharynx-specific alpha2 expression. My results show that alpha1 and alpha3 subunits cannot substitute for alpha2. Formation of chimeric constructs of alpha1, alpha2 and alpha3 pinpoints the M1--M3 transmembrane region of alpha2 as the minimal rescuing domain. This region may therefore be important for localization or, in association with another subunit, in the formation of the active channel.
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A study of the function and structure relationship of the voltage gated skeletal muscle chloride channel, CLC-1 /Wu, Wei-Ping. Unknown Date (has links)
In the skeletal muscle cell membrane, the voltage gated chloride channel, CIC-1, maintains as unusually high resting membrane conductance and thereby prevents myotonic skeletal muscle disease. Protein crystallization experiments with bacterial CIC proteins, provide the information for the three dimensional (3D) structure of CIC chloride channels. / Thesis (PhDBiomedicalScience)--University of South Australia, 2003.
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Characteristics of baculovirus - expressed in CIC-1 / by David St.John Astill.Astill, David St. John January 1996 (has links)
Bibliography: p. 159-171. / xviii, 171 p., [61] leaves of plates : ill. ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (Ph.D.)--University of Adelaide, Dept. of Physiology, 1996?
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Using alpha-aminoxy acids as building blocks to construct anion receptors and synthetic chloride channelsLi, Xiang, January 2008 (has links)
Thesis (Ph. D.)--University of Hong Kong, 2008. / Also available in print.
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Chloride channel in glioma cell invasionSin, Sai-lung, Steven. January 2008 (has links)
Thesis (M. Phil.)--University of Hong Kong, 2009. / Includes bibliographical references (leaves 82-97) Also available in print.
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Modulation and gating of the GABA[subscript A] receptor : the role of the alpha subunit /O"Shea, Sean Michael. January 2000 (has links)
Thesis (Ph. D.)--University of Chicago, Dept. of Neurobiology, Pharmacology and Physiology, June 2000. / Includes bibliographical references. Also available on the Internet.
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CFTR chloride channels novel targets for cardioprotection against ischemia and perfusion injury /Xiang, Yang Sunny. January 2008 (has links)
Thesis (Ph. D.)--University of Nevada, Reno, 2008. / "December 2008." Includes bibliographical references. Online version available on the World Wide Web.
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