This thesis addresses the problem of building a Cognitive Radio that has the ability to interact with human users in a better way by making use of Quality of Experience (QoE) as its basis and marshalling its resources optimally around the user. Salient activities of this thesis include: Analysis of CR leads to the definition of its basic functional blocks such as cognition, learning and adaptation of radio behaviour in a multi-disciplinary manner. CR tracts signal processing for radio and sensors, cognitive and behavioural psychology for user intelligence, machine learning and AI for decision systems and optimization etc. Therefore it provides a rich, fertile area to make lateral connections across diverse helds. This thesis proposes a broad definition for CR (called as Unifed Cognitive Radio) inspired by key foundation works described in literature. Besides, it also describes its functionality and its ecosystem. Taking cue from the definition of UCR, this thesis proposes architectural frame-works for various sub-systems. Also their design and implementation is achieved with the aid of a comprehensive tested setup and is tested using realistic scenarios. Builds a set of intelligent decision systems that help to achieve the set goal. This involves various design decisions with a set of diverse algorithms from the world of signal processing, machine learning and articial intelligence. Transitioning disparate small functional entities (mostly built around experiments) into an integrated system that works in real-world environment is the key aspect of this thesis. It is definitely a challenging task. Therefore, starting from deterring the architectural reference frameworks for realizing various sub-systems of UCR to an evaluation based on integrated scenario, this being an important final step constitutes a sign cant amount of work. Analysis and implementation of the integrated system to meet the desired end functionality - QoE centricity of the CR system to satisfy the needs of the end user better is the contribution of this thesis