Laotian American students attending universities across the U.S. are first-, second-, and third-generation American. This generation status, along with their families' unique immigration experiences, likely impacts their adjustment to college. Data from the 2000 U.S. Census indicates a very low representation of Laotian Americans (7.6%) in the cluster of Asian Americans who have attained at least a Bachelor?s degree (42.7%). This low representation calls for further research on the Laotian American population to discover ways to increase these numbers. This study examines the mediating effect of campus connectedness on ethnic identity and college persistence attitudes and on other-group orientation and college persistence attitudes. It also examines mean group differences on campus connectedness by cultural orientation, among 82 low-land Laotian American college students. Results reveal that campus connectedness does not mediate the relationship between ethnic identity and college persistence attitudes. A mediation effect exists for campus connectedness on: 1) ethnic identity cognitive clarity (EI-clarity) and persistence and 2) other-group orientation and persistence. Mean group differences on campus connectedness by cultural orientation appear in the results.