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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
41

Colorectal cancer screening in Latin America: Are we still in the Stone Age?

Aedo,m, Karla P, Conde, Leslye F, Pereyra Elías, Reneé 06 1900 (has links)
Cartas al editor
42

Jaundice Secondary to Isolated Porta Hepatis Metastasis in Colorectal Cancer: Case Report and Review of the Literature

Youssef, Souad S., Kumar, Pullatikurthi Pradeep 01 March 2004 (has links)
Colorectal cancer occurs mainly after the age of 50. The liver is the most frequent site of metastases, although isolated metastases to the porta hepatis are rarely reported in the literature. From 1924 to 1993, only 16 cases of periportal lymph nodes metastases were reported. We report a case of jaundice secondary to porta hepatis metastases from primary colorectal cancer. The appearance of symptoms was concurrent with the elevation of carcinoembryonic antigen in our case. This emphasizes the importance of polymerase chain reaction to detect the small amount of carcinoembryonic antigen transcript in blood or in peritoneal fluid before the appearance of symptoms. Polymerase chain reaction allows the prediction of high risk of recurrence and the presence of micrometastases. More trials are needed to assess the outcome after treatment by adjuvant chemotherapy for micrometastases.
43

Fungal inflammatory masses masquerading as colorectal cancer: a case report

Ilyas, Mohammed I. Mohammed, Jordan, Sean A., Nfonsam, Valentine January 2015 (has links)
BACKGROUND: Non malignant invasive tumors of the colon and rectum are very rare. Gastrointestinal Basidiobolomycosis can present as a mass lesion mimicking colorectal cancer. CASE PRESENTATION: A 56 year old Caucasian male was evaluated for abdominal and pelvic pain for 4 weeks complicated by acute urinary retention. Radiological evaluation showed him to have recto-sigmoid and cecal mass. Endoscopic examination and biopsies did not reveal a definite diagnosis. Computerized tomography guided biopsy of the mass showed fungal elements consistent with gastrointestinal basidiobolomycosis. He was treated with Itraconazole for 12 months with very good clinical and radiological response. CONCLUSION: Basidiobolomycosis of the gastrointestinal tract should be considered during evaluation of colorectal masses with atypical presentation. It is a rare entity seen more in endemic regions of the world for basidiobolomycosis including southwestern United States.
44

A meta-analysis of MSI frequency and race in colorectal cancer

Ashktorab, Hassan, Ahuja, Sadhna, Kannan, Lakshmi, Llor, Xavier, Nathan, Ellis, Xicola, Rosa M., Adeyinka, Laiyemo O., Carethers, John M., Brim, Hassan, Nouraie, Mehdi 09 November 2014 (has links)
PURPOSE: African Americans (AA) are at a higher risk of colorectal cancer (CRC) and some studies report a higher frequency of microsatellite instability (MSI) in this population while others report lower frequency compared to Caucasians. AIM: To determine and evaluate the association of race and clinical factors with MSI frequency through meta-analysis. METHODS: Twenty-two studies out of 15,105 (1997-2015) were evaluated after a search in different literature databases, using keywords "colorectal cancer, microsatellite instability, African Americans, Caucasians and Hispanics". We used random effect meta-analysis to calculate the MSI frequency in all studies as well as in African American and Caucasian samples. Meta-regression analysis was used to assess the univariate effect of race, gender, age, tumor location and stage on MSI frequency. RESULTS: The overall MSI frequency among CRCs was 17% (95% CI: 15%-19%, I-2 = 91%). In studies with available race data, The MSI rate among AAs, Hispanics and Caucasians were 12%, 12% and 14% respectively and was not significantly different. Sub-group analysis of studies with racial information indicates MSI OR of 0.78 for AAs compared to Caucasians. CONCLUSION: CRCs demonstrate an overall MSI frequency of 17%. MSI frequency differences between AAs and Caucasians were not pronounced, suggesting that other factors contribute to the racial disparity. The methodological approaches and biological sources of the variation seen in MSI frequency between different studies need to be further investigated.
45

The contribution of cyclooxygenase-1 and -2 in murine colorectal adenocarcinoma growth

Brown, Joanne Rosalie January 2001 (has links)
No description available.
46

Effects of N-3 polyunsaturated fatty acids on proliferation and apoptosis of colonic epithelial cells

Latham, Peter January 1999 (has links)
No description available.
47

The role of the adenomatous polyposis coli gene product in growth control, diffrentiation and apoptosis in colonic epithelial cells

Browne, Sara J. January 1997 (has links)
No description available.
48

Mathematical modelling for early detection and treatment of cancer

Jones, Simon Keith January 1997 (has links)
No description available.
49

Genotoxicity studies with potential large bowel carcinogens

Blakeborough, M. H. January 1987 (has links)
No description available.
50

The thymidylate synthase inhibitor ZD 1694 (TOMUDEX) : pharmacological studies in mouse and man

Farrugia, David Carmel January 1998 (has links)
No description available.

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