In laboratory work and working with Biotage’s Selekt Enkel chromatography system, it is common that operators are exposed to harmful and bad-smelling solvents gases. These are common issues that Biotage wants the students to solve. For this thesis work, the mission and task is to propose the best possible design of a Fume Cover that can remove or at least reduce those certain issues. To understand and gain the necessary knowledge, different data-gathering methods like workshops with staff and an extensive literature study of solvents and materials helped to establish a good design framework. Three concepts were built as 3D – models. The concept of Pugh’s iterative improvement method was used to produce an even better concept than the previous three. The chosen concept was iteratively improved for manufacturing and tested in an airflow experiment with carbon dioxide ice determining the optimal design. The conclusion is that it is possible to design a fume cover to reduce the solvent gas exposure, but further testing with light solvent gases and redesign will be required.