Made available in DSpace on 2014-12-17T14:13:58Z (GMT). No. of bitstreams: 1 DaniloLFM.pdf: 299799 bytes, checksum: 873a8a95a8ec000d4923f4b906406ecb (MD5) Previous issue date: 2007-03-09 / Objective- Convinced that periodontium, many times, can show alterations in human health, the aim of these studies was to investigate the periodontal situation in patients with endocrine-metabolic disorders such as, Berardinelli-Seip Syndrome, hyperthyroidism, hypothyroidism and acromegaly. Methods- Eight patients with Berardinelli-Seip Syndrome, 16 acromegalics, 30 hypothyroids, 30 hyperthyroids, and a control group with 35 patients were evaluated. Clinical attachment loss, probing depth, gingival bleeding index, gingival overgrowth and Index of Decayed, Missing and Filled Teeth were measured in each patient. All ethical aspects were rigidly observed, being the study conducted after its approval by the University of Fortaleza Research Ethics Committee. Results- The presence of periodontitis was marked in hyperthyroids and in patients with Berardinelli-Seip Syndrome. Hypothyroids showed not much presence of periodontitis, while all acromegalics presented absence of periodontitis. Conclusions- The protective effect of periodontitis in acromegalic patients is a new finding, whose mechanisms are not yet clear, but may be related to the anabolic effects of growth hormone. The presence of periodontitis in Berardinelli-Seip Syndrome may occur due the early onset of diabetes. In hyperthyroids, the high prevalence of periodontitis could be linked to thyroid hormones effects on bone, explaining also the minor prevalence in hypothyroids / Objetivo- Com a convic??o de que o periodonto, muitas vezes, pode ser um sinalizador de desequil?brios da sa?de humana, os presentes estudos tiveram como objetivo investigar a situa??o periodontal de pacientes com dist?rbios end?crino-metab?licos, destacando-se a S?ndrome de Berardinelli-Seip, hipertireoidismo, hipotireoidismo e acromegalia. M?todos- Foram avaliados 8 pacientes com S?ndrome de Berardinelli-Seip, 30 hipertire?ideos, 30 hipotire?ideos e 16 acromeg?licos, al?m de 35 pacientes que fizeram parte do grupo controle. Perda de inser??o cl?nica, profundidade de sondagem, ?ndice de sangramento gengival, aumento gengival e ?ndice de dentes cariados, perdidos e obturados foram os par?metros investigados em cada paciente. Todos os aspectos ?ticos foram rigidamente observados, sendo o estudo conduzido ap?s a aprova??o pelo Comit? de ?tica em Pesquisa da Universidade de Fortaleza. Resultados- A presen?a de periodontite foi marcante nos pacientes hipertire?ideos e naqueles com S?ndrome de Berardinelli-Seip. Os pacientes hipotire?ideos mostrarm pouca presen?a de periodontite, enquanto todos os acromeg?licos apresentaram aus?ncia de periodontite. Conclus?o- O efeito protetor dos acromeg?licos em rela??o ? periodontite ? um novo achado cujos mecanismos ainda n?o est?o claros, mas podem estar relacionados com os efeitos anab?licos do horm?nio de crescimento. A presen?a de periodontite na S?ndrome de Berardinelli-Seip pode ocorrer devido ? precoce presen?a de diabetes. Nos hipertire?ideos, a alta preval?ncia de periodontite pode estar ligada aos efeitos dos horm?nios tireoideanos no osso, explicando a menor preval?ncia nos hipotire?ideos