Thesis (Ph. D.)--University of Washington, 1999. / Vita. Includes bibliographical references (leaves 61-70).

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Thesis (M.S.)--State University of New York at Binghamton, Department of Biological Sciences, 2008. / Includes bibliographical references.

Thesis (M.Sc.) -- Memorial University of Newfoundland. 1974. / Typescript. Bibliography : leaves 60-67. Also available online.

A study of the vocalizations and syringeal anatomy of the common crow was conducted between 1964 and 1966. Intensive documentation of the sounds produced by the common crow, related to the appropriate behavioral context in which each sound occurs in the wild, was the primary objective of this research. Wild crows were tested with recordings of captive and wild crow vocalizations to determine the nature of the important calls and signals of this species. Common crows were also tested with "distress calls" of three sympatric species. The objectives of the syringeal research was to 1) determine how sound is produced by the common crow and 2) work out the anatomy and probable function of the syringeal components in this species. Fifteen "primary vocalizations" were documented in the common crow. They were defined as sounds which caused responses among crows. Twelve “other vocalizations” were documented in this species. They were defined as sounds which caused no responses among crows. All of the vocalizations of the common crow were not documented in this study. Careful dissections of 55 common crows collected in the field revealed that four pairs of bronchial rings, five tracheal rings, one pair of external tympaniform membranes, one pair of auxiliary membranes, and six pairs of muscles are the components of sound production in the syrinx. Probable functions of these and other syringeal parts are discussed. / Master of Science

This thesis uses the short story form to examine the influence of myth, magick, and the supernatural on the interstitial areas of the United States. The power of words as a force for change figures prominently in these stories. This thesis looks at the monstrous as it moves in the darkness and in the minds of humans, but also at the tremendous depths of compassion and courage we find in ourselves when faced with monstrous situations.

Diclofenac has previously been shown to be toxic in three species of Gyps vultures (G. bengalensis, G. tenuirostris, and G. indicus) on the Indian subcontinent. Due to the devastating effect on the population of vultures (>99.9% species mortality), numerous efforts were initiated in order to protect the species. One such effort involved the removal of further threats to the species. At present the major threat identified has been the other non-steroidal drugs (NSAIDs) available for veterinary use. From research on ketoprofen and meloxicam (the former toxic and the latter safe), it was evident that toxicity was not general for the class of NSAIDs and that other factors played a role in toxicity. This unfortunately meant that each drug had to be tested individually in the vulture. While possible, the endangered status of vulture globally makes this approach unethical. As a result an alternate method of testing needed to be validated or sought. It was believed that a surrogate model could be the answer. The aim of this study was to establish if the crow could serve as such a surrogate model. The toxic effect of diclofenac in crows (n=6) was evaluated in a two cross over studies at doses of 0.8 and 10 mg/kg. No signs of toxicity were evident during the period of clinical monitoring, or necropsy or clinical pathology. In addition the drug was barely detectable in the birds and was described by a half-life of elimination of approximately 2.5 hours. To better explain the absence of observable toxicity, a follow-up study was initiated using freshly harvested renal tubular epithelial (RTE) cells and hepatocytes in a cell culture assay previously validated for cytotoxicity and reactive-oxidative generation. In general, the in vitro study results showed the hepatocytes and RTE cells to be tolerant to the presence of diclofenac, with cell viability remaining in the region of 80%. In contrast meloxicam appeared to be more toxic as previously seen with chicken primary RTE cells. Based on the in vivo and in vitro culture results, it was speculated that the absence of toxicity in the crow was due to a combination of rapid half-life of metabolism in combination with low susceptibility of the cells to toxicity. To further explain the role of metabolism in toxicity, meta-analysis of pharmacokinetic data for the domestic chicken (Gallus gallus</i.), African White-backed (Gyps africanus), Cape Griffon (Gyps coprotheres) and Turkey vultures (<i<Cathartes aura) were evaluated for trends in toxicity. The data clearly showed a trend toward toxicity when the half-life of elimination increased. It was therefore concluded that toxicity in Gyps species is probably related to zero-order metabolism, and therefore cannot be predicted by a surrogate model due to inter-species differences in metabolism. The crow is therefore not a surrogate model for toxicity testing in the place of the vulture. Copyright / Dissertation (MSc)--University of Pretoria, 2011. / Paraclinical Sciences / unrestricted